Docteur Victor LAURENT
✨ Profil synthétique
IA · 06/05/2026Le Docteur Victor LAURENT est un rhumatologue hospitalier à Lille, avec une production scientifique notable dans le domaine de la recherche médicale. Ses travaux de recherche, comme en témoignent ses publications, portent sur divers sujets allant de la goutte à l'imagerie ostéo-articulaire par résonance magnétique (IRM). Il a également publié des études sur la lombalgie.
Expertises présumées
- Goutte
- IRM ostéo-articulaire
- Lombalgie
- Pathologies métaboliques
- Cancérologie
- Imagerie médicale
- Rhumatologie ostéo-articulaire
Synthèse automatique à partir des sources publiques (HAL, OpenAlex, theses.fr, ClinicalTrials.gov, FAI²R, ANS). Pas une évaluation clinique. Le médecin peut corriger via son compte.
Diplômes
🎓 DES & spécialité ordinale
- DES Rhumatologie
- Rhumatologie (SM)
🎓 Diplômes
- DE Docteur en médecine
Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.
Activité de recherche & publications
Source : bases de données publiques (OpenAlex, PubMed).
h-index
11
h articles cités ≥ h fois chacun. Un h de 11 = 11 publications avec 11+ citations.
Citations
2 167
Publications
50
i10-index
12
Thématiques principales
- Cancer, Hypoxia, and Metabolism ×18
- Cancer Cells and Metastasis ×13
- Cancer, Stress, Anesthesia, and Immune Response ×12
- Adipose Tissue and Metabolism ×8
- Cancer, Lipids, and Metabolism ×8
Affiliations FR : Université Catholique de Lille · Hôpital Saint-Philibert
Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.
Bibliographie
Time-course of tophus resolution on Dual-energy CT and ultrasound after 24 months of a treat-to-target strategy: Results from GOUT-DECTUS study
2025ArticleJoint Bone Spine
L'influence persistante des fausses informations malgré leur correction : étude de validité et de nouveaux déterminants
2024Thèse
Combating false information in military situations: Striking the right balance between continued influence effect and overcorrection
2024ArticleApplied Cognitive Psychology
Insights on DHAP Aldolases ability to convert Dioxygen or a Ketone as Electrophile: use of a Strain Depleted in Triose Phosphate Isomerase
2024ArticleChemCatChem
I know It’s false, but I keep thinking as if it were true: A replication study of Johnson and Seifert’s (1994) continued influence effect
2023ArticleActa Psychologica
One Step Forward in Exploration of Class II Pyruvate Aldolases Nucleophile and Electrophile Substrate Specificity
2021ArticleChemCatChem
The Chemokine Receptor CCR3 Is Potentially Involved in the Homing of Prostate Cancer Cells to Bone: Implication of Bone-Marrow Adipocytes
2021ArticleInternational Journal of Molecular Sciences
tertiary Alcohol Formation Catalysed by a Rhamnulose-1-PhosphateAldolase : Dendroketose-1-Phosphate Synthesis
2020Chapitre
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
Localisation
Adresses géocodées via la Base Adresse Nationale (api-adresse.data.gouv.fr). Précision indicative.
Lieu de consultation
GCS GHICL HÔPITAL ST PHILIBERT
115 Rue DU GRAND BUT, 59160 Lille
☎ 0320225050Hospitalier© OpenStreetMap
Tarifs & secteur de conventionnement
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Prendre rendez-vous & contact
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Top publications · les plus citées
- 1Adipocyte-derived fibroblasts promote tumor progression and contribute to the desmoplastic reaction in breast cancer
Cancer research · 2013
Lire l'abstract Crossref ↓
Abstract Cancer-associated fibroblasts (CAF) comprise the majority of stromal cells in breast cancers, yet their precise origins and relative functional contributions to malignant progression remain uncertain. Local invasion leads to the proximity of cancer cells and adipocytes, which respond by phenotypical changes to generate fibroblast-like cells termed as adipocyte-derived fibroblasts (ADF) here. These cells exhibit enhanced secretion of fibronectin and collagen I, increased migratory/invasive abilities, and increased expression of the CAF marker FSP-1 but not α-SMA. Generation of the ADF phenotype depends on reactivation of the Wnt/β-catenin pathway in response to Wnt3a secreted by tumor cells. Tumor cells cocultivated with ADFs in two-dimensional or spheroid culture display increased invasive capabilities. In clinical specimens of breast cancer, we confirmed the presence of this new stromal subpopulation. By defining a new stromal cell population, our results offer new opportunities for stroma-targeted therapies in breast cancer. Cancer Res; 73(18); 5657–68. ©2013 AACR.
- 3Increased tolerance to artemisinin in Plasmodium falciparum is mediated by a quiescence mechanism
Antimicrobial agents and chemotherapy · 2010
Lire l'abstract Crossref ↓
ABSTRACT Artemisinin (ART)-based combination therapies (ACTs) are the first-line drugs—and often the last treatments—that can effectively cure Plasmodium falciparum infections. Unfortunately, the decreased clinical efficacy of artesunate, one of the major ART derivatives, was recently reported along the Thailand-Cambodia border. Through long-term artemisinin pressure in vitro , we have obtained an ART-tolerant strain that can survive extremely high doses of ART. We showed that drug pressure could induce a subpopulation of ring stages into developmental arrest, which can explain the ART tolerance in P. falciparum . We also observed interesting transcriptomic modifications possibly associated with the acquisition of ART tolerance. These modifications include the overexpression of heat shock and erythrocyte surface proteins and the downexpression of a cell cycle regulator and a DNA biosynthesis protein. This study highlights a new phenomenon in the Plasmodium response to ART that may explain the delayed clearance of parasites after artesunate treatment observed on the Thailand-Cambodia border and that provides important information for achieving a better understanding of the mechanisms of antimalarial resistance.
Publications scientifiques (22) — classées par pathologie
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Transversal17
▼
Transversal17
▼- The role of renal dual-energy computed tomography in exploring the gouty kidney: the RENODECT study
Annals of medicine · 2025 · Journal Article
Pascart T, Dauphin E, Yokose C, Jauffret C, et al.
📚 1 cit. - Advanced imaging techniques in crystal arthritis
Therapeutic advances in musculoskeletal disease · 2025 · Journal Article
Laurent V, Filippou G, Sirotti S, Pascart T
📚 4 cit. - I know It's false, but I keep thinking as if it were true: A replication study of Johnson and Seifert's (1994) continued influence effect
Acta psychologica · 2023 · Journal Article
Laurent V, Kosinski T, Rusinek S
📚 1 cit. - A highly selective humanized DDR1 mAb reverses immune exclusion by disrupting collagen fiber alignment in breast cancer
Journal for immunotherapy of cancer · 2023 · Journal Article
Liu J, Chiang HC, Xiong W, Laurent V, et al.
📚 44 cit.🎯 RCR 4.73 - Association of circulating PLA2G7 levels with cancer cachexia and assessment of darapladib as a therapy
Journal of cachexia, sarcopenia and muscle · 2021 · Journal Article
Morigny P, Kaltenecker D, Zuber J, Machado J, et al.
📚 27 cit.🎯 RCR 1.55 - The Chemokine Receptor CCR3 Is Potentially Involved in the Homing of Prostate Cancer Cells to Bone: Implication of Bone-Marrow Adipocytes
International journal of molecular sciences · 2021 · Journal Article
Guérard A, Laurent V, Fromont G, Estève D, et al.
📚 20 cit.🎯 RCR 1.44 - Periprostatic Adipose Tissue Favors Prostate Cancer Cell Invasion in an Obesity-Dependent Manner: Role of Oxidative Stress
Molecular cancer research : MCR · 2019 · Journal Article
Laurent V, Toulet A, Attané C, Milhas D, et al.
📚 96 cit.🎯 RCR 4.36🔬→🩺 Translationnel - Synthesis of Branched-Chain Sugars with a DHAP-Dependent Aldolase: Ketones are Electrophile Substrates of Rhamnulose-1-phosphate Aldolases
Angewandte Chemie (International ed. in English) · 2018 · Journal Article
Laurent V, Darii E, Aujon A, Debacker M, et al.
📚 22 cit.🎯 RCR 1.14 - Mammary adipocytes stimulate breast cancer invasion through metabolic remodeling of tumor cells
JCI insight · 2017 · Journal Article
Wang YY, Attané C, Milhas D, Dirat B, et al.
📚 362 cit.🎯 RCR 12.70🔬→🩺 Translationnel - An AMP-activated protein kinase-stabilizing peptide ameliorates adipose tissue wasting in cancer cachexia in mice
Nature medicine · 2016 · Journal Article
Rohm M, Schäfer M, Laurent V, Üstünel BE, et al.
📚 121 cit.🎯 RCR 4.05 - [Dissemination of prostate cancer: a way paved of fat]
Medecine sciences : M/S · 2016 · News
Laurent V, Guérard A, Toulet A, Valet P, et al.
📚 1 cit. - Periprostatic adipocytes act as a driving force for prostate cancer progression in obesity
Nature communications · 2016 · Journal Article
Laurent V, Guérard A, Mazerolles C, Le Gonidec S, et al.
📚 239 cit.🎯 RCR 8.26🔬→🩺 Translationnel - [Adipose tissue and cancer: a high risk tandem]
Medecine sciences : M/S · 2014 · English Abstract
Laurent V, Nieto L, Valet P, Muller C
📚 11 cit. - Adipocyte-derived fibroblasts promote tumor progression and contribute to the desmoplastic reaction in breast cancer
Cancer research · 2013 · Journal Article
Bochet L, Lehuédé C, Dauvillier S, Wang YY, et al.
📚 415 cit.🎯 RCR 11.46🔬→🩺 Translationnel - Adipose tissue and breast epithelial cells: a dangerous dynamic duo in breast cancer
Cancer letters · 2012 · Journal Article
Wang YY, Lehuédé C, Laurent V, Dirat B, et al.
📚 174 cit.🎯 RCR 4.79🔬→🩺 Translationnel - Increased tolerance to artemisinin in Plasmodium falciparum is mediated by a quiescence mechanism
Antimicrobial agents and chemotherapy · 2010 · Journal Article
Witkowski B, Lelièvre J, Barragán MJ, Laurent V, et al.
📚 253 cit.🎯 RCR 7.17🔬→🩺 Translationnel - [Value of bone fluoride determination in osteoporotic patients treated with sodium fluoride]
Presse medicale (Paris, France : 1983) · 1989 · English Abstract
Laurent V, de Vernejoul MC, Brouard A, Terrier JL, et al.
📚 11 cit.🔬→🩺 Translationnel
Goutte3
▼
Goutte3
▼- Time-course of tophus resolution on Dual-energy CT and ultrasound after 24months of a treat-to-target strategy: Results from GOUT-DECTUS study
Joint bone spine · 2025 · Journal Article
Pascart T, Richette P, Bousson V, Ottaviani S, et al.
📚 3 cit. - Are gout patients with negative dual-energy computed tomography for monosodium urate crystal deposition easy to treat?
Rheumatology (Oxford, England) · 2025 · Journal Article
Laurent V, Jauffret C, Ducoulombier V, Pacaud A, et al.
📚 5 cit.🎯 RCR 2.25 - Factors influencing the kinetics of MSU crystal depletion measured with dual-energy CT in patients with gout
RMD open · 2023 · Journal Article
Laurent V, Jauffret C, Pacaud A, Ducoulombier V, et al.
📚 9 cit.🎯 RCR 1.61
IRM ostéo-articulaire1
▼
IRM ostéo-articulaire1
▼- The prevalence of inflammatory sacroiliitis assessed on magnetic resonance imaging of inflammatory bowel disease: a retrospective study performed on 186 patients
Alimentary pharmacology & therapeutics · 2014 · Journal Article
Leclerc-Jacob S, Lux G, Rat AC, Laurent V, et al.
📚 37 cit.🎯 RCR 1.52🔬→🩺 Translationnel
Lombalgie1
▼
Lombalgie1
▼- Low Back Pain and Sacroiliitis on Cross-Sectional Abdominal Imaging for Axial Spondyloarthritis Diagnosis in Inflammatory Bowel Diseases
Inflammatory intestinal diseases · 2020 · Journal Article
Fauny M, Cohen N, Morizot C, Leclerc-Jacob S, et al.
📚 6 cit.🔬→🩺 Translationnel
