Docteur ELISABETH GERVAIS

Bibliographie

• Impact of postpartum on patients with rheumatoid arthritis and spondyloarthritis: an ancillary analysis of the GR2 prospective cohort

  2026

  ArticleRMD Open

• Comment on: Hydroxychloroquine levels in pregnancy and materno–fetal outcomes in Systemic Lupus Erythematosus patients: Reply

  2025

  ArticleRheumatology

• NSAID exposure delays time-to-pregnancy in patients with spondyloarthritis: an analysis of the GR2 prospective cohort

  2024

  ArticleRMD Open

• Retention rate of subcutaneous TNF inhibitors in axial spondyloarthritis in a multicentre study from the RIC-FRANCE network

  2024

  ArticleScientific Reports

• Baricitinib in juvenile idiopathic arthritis: an international, phase 3, randomised, double-blind, placebo-controlled, withdrawal, efficacy, and safety trial

  2023

  ArticleThe Lancet

• Pregnancy outcomes in women with primary Sjögren's syndrome: an analysis of data from the multicentre, prospective, GR2 study

  2023

  ArticleThe Lancet Rheumatology

• Pseudopolyarthrite rhizomélique associée au syndrome de Gougerot-Sjögren primitif : étude multicentrique rétrospective française

  2022

  ArticleRevue du Rhumatisme

• Characterisation of a high-risk profile for maternal thrombotic and severe haemorrhagic complications in pregnant women with antiphospholipid syndrome in France (GR2): a multicentre, prospective, observational study

  2022

  ArticleThe Lancet Rheumatology

Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).

Lieu de consultation

• CHU LA MILETRIE

  2 Rue DE LA MILETRIE, 86021 Poitiers

  ☎ 0549444444Hospitalier🏥 Centre CHU ↗🏥 Voir cet établissement

Tarifs & secteur de conventionnement

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Prendre rendez-vous & contact

Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Articles de presse (2)

Source : Google News (recherche par nom complet — homonymes possibles, vérifier le contenu).

• Rhumatologie : expertise et recherche au CHU de Poitiers - Site du CHU de Poitiers

  📰 Site du CHU de Poitiers · 20/05/2022

  <a href="https://news.google.com/rss/articles/CBMiiwFBVV95cUxOQk5EdzVTWEswaTVLXzdpYTFCQ2s0U0lZdDJZX3lVeXR1elBoQXhEWlp2WERkY05ob2lEMVBsV1JQRmZubl9wRngyWHlJMFJJLWY1bVB5dUdWVDJYbjlVSS14Y0tzTlQwdDFyc3FiNU5vbTE3MGhQdmItaWt0UlJiSXhBTGtOTzFmbUxF?oc=5" target="_blank">Rhumatologie : expertise et recherche a

• gervais-elisabeth - Site du CHU de Poitiers

  📰 Site du CHU de Poitiers · 20/05/2022

  <a href="https://news.google.com/rss/articles/CBMiowFBVV95cUxNeEhscUJ3aWlSaVlFcGQ5Y3BRLURuQ21sRUJzYW9hZGp6VHJQOUZqRnlsV2ZSajdITUlYUS1XN1dxdlRQU3V3VzJOemV3aHk3VU5FWW9icnpJXzlKbF9QSFpWSldUdm1HdHJ4VXpPNjJlaHl1MlllczU0ZlN4SzA4RE8za3pIQ2drQV9FVVdzRkhUTDJkd2UzWHpVbHotckpjajJz?oc=5" target="_blank">gervais

Top publications · les plus citées

• 1

  Methotrexate effect on immunogenicity and long-term maintenance of adalimumab in axial spondyloarthritis: a multicentric randomised trial

  RMD open · 2020

  📚 46 citations🎯 RCR 3.11Top 15% NIH🩺 Clinique🔓 Open Access📄 PDF gratuit ↗

  Lire l'abstract Crossref ↓

  Objectives Anti-drug antibodies (ADA) are responsible for decreased adalimumab efficacy in axial spondyloarthritis (SpA). We aimed to evaluate the ability of methotrexate (MTX) to decrease adalimumab immunisation. Methods A total of 110 patients eligible to receive adalimumab 40 mg subcutaneously (s.c.) every other week were randomised (1:1 ratio) to receive, 2 weeks before adalimumab (W-2) and weekly, MTX 10 mg s.c. (MTX+) or not (MTX−). ADA detection and adalimumab serum concentration were assessed at weeks 4 (W4), 8 (W8), 12 (W12) and 26 (W26) after starting adalimumab (W0). The primary outcome was the proportion of patients with ADA at W26. Four years after the study completion, we retrospectively analysed adalimumab maintenance in relation with MTX co-treatment duration. Results We analysed data for 107 patients (MTX+; n=52; MTX-; n=55). ADA were detected at W26 in 39/107 (36.4%) patients: 13/52 (25%) in the MTX+ group and 26/55 (47.3%) in the MTX− group (p=0.03). Adalimumab concentration was significantly higher in the MTX+ than MTX− group at W4, W8, W12 and W26. The two groups did not differ in adverse events or efficacy. In the follow-up study, MTX co-treatment &gt;W26 versus no MTX or ≤W26 was significantly associated with adalimumab long-term maintenance (p=0.04). Conclusion MTX reduces the immunogenicity and ameliorate the pharmacokinetics of adalimumab in axial SpA. A prolonged co-treatment of MTX&gt;W26 seems to increase adalimumab long-term maintenance.

• 2

  Colour Doppler ultrasound of temporal arteries for the diagnosis of giant cell arteritis: a multicentre deep learning study

  Clinical and experimental rheumatology · 2020

  📚 24 citations🎯 RCR 1.81
• 3

  Rheumatological features of Whipple disease

  Scientific reports · 2021

  📚 19 citations🎯 RCR 1.65🔓 Open Access📄 PDF gratuit ↗

  Lire l'abstract Crossref ↓

  AbstractWhipple disease (WD) is a rare infectious systemic disease. Rheumatologists are at the frontline of WD diagnosis due to the early rheumatological manifestations. An early diagnosis is crucial, as usual anti-rheumatic drugs, especially TNF inhibitors, may worsen the disease course. We conducted a retrospective multicentre national study from January 2010 to April 2020 to better characterize the rheumatological features of WD. Classic WD (CWD) was defined by positive periodic acid-Schiff (PAS) staining of a small-bowel biopsy sample, and non-CWD (NCWD) was defined by negative PAS staining of a small-bowel biopsy sample but at least one positive Tropheryma whipplei (TW) polymerase chain reaction (PCR) for a digestive or extradigestive specimen. Sixty-eight patients were enrolled, including 11 CWD patients. Twenty patients (30%) received TNF inhibitors during the WD course, with inefficacy or symptom worsening. More digestive symptoms and systemic biological features were observed in CWD patients than in NCWD patients, but both patient groups had similar outcomes, especially concerning the response to antibiotics and relapse rate. Stool and saliva TW PCR sensitivity were both 100% for CWD and 75% for NCWD and 89% and 60% for small-bowel biopsy sample PCR, respectively. WD encountered in rheumatology units has many presentations, which might result from different pathophysiologies that are dependent on host immunity. Given the heterogeneous presentations and the presence of chronic carriage, multiple TW PCR tests on samples from specific rheumatological sites when possible should be performed, but samples from nonspecific digestive and extradigestive sites also have great value.

Publications scientifiques (26) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

Datasets & protocoles partagés

• (Table 2) The presence and absence of whole and/or fragmented planktonic and benthic foraminifers at DSDP Hole 93-603

  Dataset1987PANGAEA

  P = present; R = rare, 0.1-&lt;3.0; C = common, 3.0-&lt;10.0; A = abundant, 10.0-40.0; D = dominant, 40.0-100.0; X: only in fraction &lt; 125 µm.

• (Table 11) Distribution of planktonic foraminifera in the early Miocene section of ODP Hole 149-900A

  Dataset1996PANGAEA

  Species abundance: R = rare, F = few, C = common, A = abundant, ? = questionable, RW = reworked, - = not present.

• (Table 15) Distribution of planktonic foraminifera in the early to early late Oligocene section of ODP Hole 149-900A

  Dataset1996PANGAEA

  Species abundance: R = rare, F = few, C = common, A = abundant, ? = questionable, RW = reworked, - = not present.

• Benthic foraminifera abundance of Hole 93-603

  Dataset2005PANGAEA

  Relative abundance: D = dominant, A = abundant, C = common, F = few, R = rare, T = trace, P = present (numerical values are abundance in percent)

• (Table 15) Distribution of planktonic foraminifera in the early to early late Oligocene section of ODP Hole 149-900A

  Dataset1996PANGAEA - Publishing Network for Geoscientific and Environmental Data

• (Table 3) Distribution of planktonic foraminifera in the early Cretaceous and early Eocene to late Oligocene sections of ODP Hole 149-897C

  Dataset1996PANGAEA - Publishing Network for Geoscientific and Environmental Data

Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).

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