M. Docteur PATRICK GEPNER
Diplômes
🎓 DES & spécialité ordinale
- Rhumatologie (SM)
📚 CES (Certificat d'Études Spéciales)
- CES Rhumatologie
🎓 Diplômes
- DE Docteur en médecine
Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.
Livres & ouvrages
La Médecine pour les Nuls, grand format, 2e éd
2023 · Pour les nuls · 884 p.
La Médecine Vite et bien pour les Nuls
2023 · Pour les nuls · 448 p.
Je découvre le corps humain Pour les Nuls
2021 · Pour les nuls · 486 p.
El cuerpo humano para Dummies
2020 · Para Dummies · 517 p.
Le corps humain pour les Nuls - Vite et bien
2019 · Pour les nuls · 494 p.
La médecine pour les nuls
2011 · Pour les nuls · 679 p.
Source : Google Books — filtre catégories médicales/santé/sciences.
Localisation
Adresses géocodées via la Base Adresse Nationale (api-adresse.data.gouv.fr). Précision indicative.
Lieu de consultation
SOCIETE D'EXERCICE LIBERAL DU DR GEPNER
20 RUE PARMENTIER, 92200 Neuilly-sur-Seine
Libéral
Tarifs & secteur de conventionnement
Prendre rendez-vous & contact
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Vidéos & interventions (1)
Source YouTube · recherche par nom (homonymes possibles).
Top publications · les plus citées
- 11,25-dihydroxyvitamin D3 potentiates the in vitro inhibitory effects of cyclosporin A on T cells from rheumatoid arthritis patients
Arthritis and rheumatism · 1989
📚 35 citations🎯 RCR 1.26Lire l'abstract Crossref ↓
AbstractTreatment of rheumatoid arthritis (RA) with cyclosporin A (CsA) has been successful, but the adverse effects of the drug have limited its use. We investigated the capacity of another immunosuppressive agent, 1,25‐dihydroxyvitamin D3 [1,25(OH)2D3], to augment the effect of CsA on in vitro T cell functions. Exposure of CD4+ cells from RA patients or from normal subjects to either molecule alone resulted in a dose‐dependent inhibition of phytohemagglutinin stimulation and interleukin‐2 (IL‐2) production that was more pronounced in cells from RA patients than in cells from normal subjects. Moreover, the action of CsA and 1, 25(OH)2D3 on RA patient T cell functions in vitro was synergistic. Thus, in the presence of the vitamin D3 metabolite, only one‐hundredth the concentration of CsA was required to produce the same effect on IL‐2 production as that produced by CsA alone. IL‐2 receptor expression was also reduced by the addition of both drugs. In contrast, IL‐1 production by RA monocytes was not affected by CsA and 1,25(OH)2D3, either together or alone, and addition of IL‐1 did not restore the ability of CD4+ cells from RA patients to secrete IL‐2. Exogenous IL‐2 reversed a large part of the inhibitory effect induced by both CsA and 1, 25(OH)2D3, indicating that the immunosuppressive properties of these agents are mediated by the inhibition of IL‐2 secretion. This synergy between 2 molecules that are biochemically very different suggests the existence of one or several sites of interaction that take place during the early stages of T cell activation.
- 2[Systemic reaction induced my minocycline treatment: a report of four patients and a review of the literature]
La Revue de medecine interne · 1999
📚 14 citations - 3["Primary" pulmonary arterial hypertension associated with HIV infection. Two cases]
Presse medicale (Paris, France : 1983) · 1992
📚 14 citations
Publications scientifiques (7) — classées par pathologie
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Transversal5
▼
Transversal5
▼- [Crowned dens syndrome: three new cases]
La Revue de medecine interne · 2003 · Case Reports
Aouba A, Lidove O, Gepner P, Brousse C, et al.
📚 9 cit. - [Does arthritis due to varicella zoster virus exist?]
Revue du rhumatisme et des maladies osteo-articulaires · 1992 · Case Reports
Gepner P, Piette AM, Patrat JF, Graveleau P, et al.
📚 2 cit. - ["Primary" pulmonary arterial hypertension associated with HIV infection. Two cases]
Presse medicale (Paris, France : 1983) · 1992 · Case Reports
Piette AM, Legoux B, Gepner P, Chapman A
📚 14 cit. - 1,25-dihydroxyvitamin D3 potentiates the in vitro inhibitory effects of cyclosporin A on T cells from rheumatoid arthritis patients
Arthritis and rheumatism · 1989 · Journal Article
Gepner P, Amor B, Fournier C
📚 35 cit.🎯 RCR 1.26🔬→🩺 Translationnel - [Immunotolerance of RU 41740]
Presse medicale (Paris, France : 1983) · 1988 · Clinical Trial
Gepner P
📚 2 cit.🩺 Clinique
Revue générale1
▼
Revue générale1
▼- [Systemic reaction induced my minocycline treatment: a report of four patients and a review of the literature]
La Revue de medecine interne · 1999 · Case Reports
Piette AM, Ramanoelina J, Gepner P, Larroche C, et al.
📚 14 cit.
SAPL1
▼
SAPL1
▼- [Antiphospholipid syndrome. 20 cases]
Presse medicale (Paris, France : 1983) · 1994 · English Abstract
Piette AM, Mourad JJ, Karmochkine M, Didon D, et al.
📚 6 cit.

