M. Docteur JEAN-LOUIS FRANCK

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Adresses géocodées via la Base Adresse Nationale (api-adresse.data.gouv.fr). Précision indicative.

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• CABINET DU DR JEAN-LOUIS FRANCK

  CL MUTUALISTE DE PESSAC — 46 AVENUE DU DR SCHWEITZER, 33600 Pessac

  ☎ 0556465627Libéral
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Tarifs & secteur de conventionnement

Prendre rendez-vous & contact

Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Vidéos & interventions (7)

Source YouTube · recherche par nom (homonymes possibles).

• 1h30

  Faites entrer l’accusé : Romain Dupuy, les infirmières de Pau

  Faites entrer l’accusé - Officielle · 803 k vues

• 0:42

  UBU ROI ・Le Grenier de Toulouse

  Le Grenier de Toulouse · 739 vues

• 1h29

  Faites entrer l'accusé - Le mystère de Hassel - L'affaire Kolber - S16

  Faites entrer l’accusé - Officielle · 1.4 M vues

• 1:00

  Reins Spondylarthrite ankylosante Naturablue Naturagold Témoignage

  Témoignages Bien Etre Particulier & Animaux · 140 vues

• 17:09

  Frédéric Ricolfi, JFR 2019 Symposium imagerie augmentée

  Canon Medical Systems Europe · 496 vues

• 58:11

  Kèk move manje ki bay maladi, Dr Dieudonne Jean-Baptiste,specialiste en medecine fonctionnelle

  Roldan Celestin · 2 k vues

• 0:53

  Campagne Ne Lui Tournez Pas Le Dos

  Association AFLAR · 611 vues

Top publications · les plus citées

• 1

  Transforming growth factor-β increases interleukin-13 synthesis via GATA-3 transcription factor in T-lymphocytes from patients with systemic sclerosis

  Arthritis research & therapy · 2015

  📚 23 citations🔓 Open Access

  Lire l'abstract Crossref ↓

  Abstract Introduction Transforming growth factor (TGF)-β and interleukin (IL)-13 play a crucial role in the pathogenesis of systemic sclerosis (SSc), partly through activation of collagen production that leads to fibrosis. The aim of the present study was to determine whether TFG-β alters IL-13 production in T lymphocytes from patients with SSc from that seen in those of healthy donors. Methods IL-13 mRNA and protein synthesis under TFG-β exposure was measured in circulating T lymphocytes from healthy donors and patients with SSc and also in the Jurkat Th2 T-cell line, using quantitative real-time PCR and fluorescence-activated cell sorting analysis, respectively. The involvement of Smad and GATA-3 transcription factors was assessed by using specific inhibitors and small interfering RNA, and the binding capacity of GATA-3 to the IL-13 gene promoter was evaluated by chromatin immunoprecipitation assay. Results TGF-β induced a significant decrease in IL-13 mRNA and protein levels in lymphocytes from healthy donors (mean [±SD] inhibition of 30 % ± 10 % and 20 % ± 7 %, respectively; p < 0.05). In contrast, TGF-β promoted a significant increase in IL-13 mRNA levels and IL-13 synthesis by CD4+ and CD8+ T-cell subtypes from patients with SSc, with respective increases of 2.4 ± 0.3-fold, 1.6 ± 0.05-fold and 2.7 ± 0.02-fold. The involvement of the Smad signaling pathway and upregulation of GATA-3 binding capacity on the IL-13 promoter in lymphocytes from patients with SSc contributed to the effect of TGF-β on IL-13 production. Conclusions These results demonstrate that TGF-β upregulates IL-13 synthesis through GATA-3 expression in the T lymphocytes of patients with SSc, confirming that the GATA-3 transcription factor can be regarded as a novel therapeutic target in patients with SSc.

• 2

  Recurrent congenital toxoplasmosis in a woman with lupus erythematosus

  Prenatal diagnosis · 1995

  📚 14 citations

  Lire l'abstract Crossref ↓

  AbstractWe describe the case of a patient with systemic lupus erythematosus, treated by corticosteroids, who presented during two successive pregnancies with serological reactivation of toxoplasmosis associated with fetal lesions. The first infected fetus died in utero with signs of hydrops. The second fetus was treated in utero with a combination of sulfadoxine and pyrimethamine, administered to the mother, and is now well. The increasing number of immunocompromised pregnant patients with immunity to Toxoplasma gondii may lead to a higher risk of reactivation of maternal toxoplasmosis and congenital infection.

• 3

  [Seropositive palindromic rheumatism and pulmonary rheumatoid nodule: apropos of a case]

  Revue du rhumatisme et des maladies osteo-articulaires · 1982

  📚 3 citations

Publications scientifiques (5) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

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