Docteur EVE DAVID-VAUDEY

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• HOPITAL JOSEPH DUCUING TOULOUSE

  15 Rue DE VARSOVIE, 31076 Toulouse

  ☎ 0561773400Hospitalier🏥 Voir cet établissement

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Top publications · les plus citées

• 1

  T2 relaxation time measurements in osteoarthritis

  Magnetic resonance imaging · 2004

  📚 180 citations🎯 RCR 6.67Top 5% NIH
• 2

  Particular HLA-DRB1 shared epitope genotypes are strongly associated with rheumatoid vasculitis

  Arthritis and rheumatism · 2004

  📚 54 citations🎯 RCR 1.47

  Lire l'abstract Crossref ↓

  AbstractObjectiveTo examine the relationship of the HLA–DRB1 shared epitope (SE) to rheumatoid vasculitis, using individual patient data (IPD) meta‐analytic methods.MethodsPublished studies that enrolled adult patients with rheumatoid arthritis (RA) were identified by searches of Medline and Embase, and by manual searches of medical journals. All authors were contacted for IPD. Meta‐analyses were performed to assess the association of SE presence, dose, and genotype with rheumatoid vasculitis.ResultsA total of 14 studies and 1,568 patients (129 with vasculitis) were included in the analysis. RA patients with vasculitis were significantly more likely to have rheumatoid nodules (odds ratio [OR] 2.5, 95% confidence interval [95% CI] 1.5–3.9], but there was no significant association with male sex, rheumatoid factor positivity, or erosive disease. No significant association was observed between the presence of the SE (i.e., 1 or 2 alleles versus 0 alleles) and rheumatoid vasculitis (summary OR 1.4, 95% CI 0.7–2.7). Analysis by SE genotype, however, demonstrated a striking relationship of vasculitis to 3 genotypes containing a double dose of the SE, specifically HLA–DRB1*0401/*0401 (OR 6.2, 95% CI 1.01–37.9), *0401/*0404 (OR 4.1, 95% CI 1.1–16.2), and *0101/*0401 (OR 4.0, 95% CI 1.4–11.6).ConclusionThe HLA–DRB1 SE genotypes *0401/*0401, *0401/*0404, and *0101/*0401 may be of particular importance to rheumatoid vasculitis. It is hoped that additional investigation of these and other SE genotypes will lead to improved insight into the mechanisms influencing the clinical expression of RA.

• 3

  Fourier Transform Infrared Imaging of focal lesions in human osteoarthritic cartilage

  European cells & materials · 2005

  📚 50 citations🎯 RCR 1.71🔓 Open Access

Publications scientifiques (5) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

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