Mme Docteur EMILIE DELATTRE

Bibliographie

• Endocavitary right ventricular cardiac metastasis of a Lung adenocarcinoma treated by surgery: a case report about a novel multimodal therapeutic approach

  2023

  ArticleCase Reports in Oncology

Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).

Localisation

Adresses géocodées via la Base Adresse Nationale (api-adresse.data.gouv.fr). Précision indicative.

Lieux de consultation

• CH LOUIS PASTEUR DOLE

  Avenue LEON JOUHAUX, 39108 Dole

  ☎ 0384798080Libéral🏥 Centre CH ↗🏥 Voir cet établissement

• CABINET DU DR EMILIE DELATTRE

  7BIS ROUTE DE LYON, 25440 Quingey

  Libéral
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  📷 Street View ↗🗺️ Maps ↗OSM ↗

Tarifs & secteur de conventionnement

Prendre rendez-vous & contact

Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Top publications · les plus citées

• 1

  SAPHO syndrome treatment with intravenous pamidronate. Retrospective study of 22 patients

  Joint bone spine · 2014

  📚 22 citations🎯 RCR 1.19
• 2

  Association of Primary Sjögren's Syndrome and Vitamin B12 Deficiency: A Cross-Sectional Case-Control Study

  Journal of clinical medicine · 2020

  📚 6 citations🔓 Open Access📄 PDF gratuit ↗

  Lire l'abstract Crossref ↓

  Descriptive and retrospective studies without control groups have suggested a possible association between primary Sjögren’s syndrome (pSS) and vitamin B12 (B12) deficiency. This is of importance because several mucosal and neurological features are common to these two conditions and could be prevented or reversed in case of B12 deficiency. We aimed to evaluate the association between pSS and B12 deficiency. We prospectively assessed the B12 status of 490 patients hospitalized in an internal medicine department over a 15-week period. Patients with pernicious anemia were excluded. We extracted patients with pSS and paired them with controls according to age and sex, with a 1:5 ratio. Twenty-one pSS patients were paired with 105 control patients. The median age was 70 years old (51–75) and 95.2% of patients were women. The plasma B12 level was lower in pSS patients (329 (293–521) ng/L vs. 456 (341–587) ng/L, p < 0.0001). B12 deficiency was associated with pSS (42.9% among pSS patients vs. 11.4% among controls), even after adjustment for other causes of B12 deficiency (OR 6.45 (95%CI: 2.08–20.0)). In conclusion, pSS appeared to be associated with B12 deficiency, even after the exclusion of pernicious anemia. This justifies screening and treating B12 deficiency in pSS patients.

• 3

  An immuno-lipidomic signature revealed by metabolomic and machine-learning approaches in labial salivary gland to diagnose primary Sjögren's syndrome

  Frontiers in immunology · 2023

  📚 5 citations🔓 Open Access📄 PDF gratuit ↗

  Lire l'abstract Crossref ↓

  IntroductionAssessing labial salivary gland exocrinopathy is a cornerstone in primary Sjögren’s syndrome. Currently this relies on the histopathologic diagnosis of focal lymphocytic sialadenitis and computing a focus score by counting lym=phocyte foci. However, those lesions represent advanced stages of primary Sjögren’s syndrome, although earlier recognition of primary Sjögren’s syndrome and its effective treatment could prevent irreversible damage to labial salivary gland. This study aimed at finding early biomarkers of primary Sjögren’s syndrome in labial salivary gland combining metabolomics and machine-learning approaches.MethodsWe used a standardized targeted metabolomic approach involving high performance liquid chromatography coupled with mass spectrometry among newly diagnosed primary Sjögren’s syndrome (n=40) and non- primary Sjögren’s syndrome sicca (n=40) participants in a prospective cohort. A metabolic signature predictive of primary Sjögren’s syndrome status was explored using linear (logistic regression with elastic-net regularization) and non-linear (random forests) machine learning architectures, after splitting the data set into training, validation, and test sets.ResultsAmong 126 metabolites accurately measured, we identified a discriminant signature composed of six metabolites with robust performances (ROC-AUC = 0.86) for predicting primary Sjögren’s syndrome status. This signature included the well-known immune-metabolite kynurenine and five phospholipids (LysoPC C28:0; PCaa C26:0; PCaaC30:2; PCae C30:1, and PCaeC30:2). It was split into two main components: the first including the phospholipids was related to the intensity of lymphocytic infiltrates in salivary glands, while the second represented by kynurenine was independently associated with the presence of anti-SSA antibodies in participant serum.ConclusionOur results reveal an immuno-lipidomic signature in labial salivary gland that accurately distinguishes early primary Sjögren’s syndrome from other causes of sicca symptoms.

Publications scientifiques (6) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

Datasets & protocoles partagés

• Example Data and Models for "Atlas Alignment" Project

  Dataset2021Zenodo

  <strong>Overview</strong> This zip folder contains example data and models for "Atlas Alignment". "Atlas Alignment" is the Blue Brain toolbox to perform multimodal image registration. It includes both traditional and sup

• BlueBrain/Atlas-Download-Tools: v0.3.0

  Software2021Zenodo

  Search, download, and prepare brain atlas data.

• Blue Brain Search

  Software2021Zenodo

  <strong>Blue Brain Search</strong> is a text mining toolbox to perform semantic literature search and structured information extraction from text sources. This project originated from the Blue Brain Project efforts on ex

• Example Data and Models for "Atlas Alignment" Project

  Dataset2021Zenodo

  <strong>Overview</strong> This zip folder contains example data and models for "Atlas Alignment". "Atlas Alignment" is the Blue Brain toolbox to perform multimodal image registration. It includes both traditional and sup

• Data and models for Blue Brain Search

  Dataset2021Zenodo

  This archive contains the data and models for Blue Brain Search. They are in the format of a DVC remote. Indeed, Blue Brain Search uses DVC to track machine learning models and datasets and to make them shareable and rep

• Data and models for Blue Brain Search

  Dataset2021Zenodo

  This archive contains the data and models for Blue Brain Search. They are in the format of a DVC remote. Indeed, Blue Brain Search uses DVC to track machine learning models and datasets and to make them shareable and rep

Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).

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