Professeur Alain CANTAGREL
✨ Profil synthétique
IA · 06/05/2026Le Professeur Alain CANTAGREL est un rhumatologue libéral à Castelnaudary avec une activité de recherche significative, comme en témoignent son h-index de 54 et ses 363 publications. Ses travaux de recherche portent principalement sur les maladies auto-immunes et inflammatoires, notamment la polyarthrite rhumatoïde, la spondyloarthrite et le lupus érythémateux systémique. Il a également dirigé des thèses sur l'immunopathologie et l'immunogénétique humaines.
Expertises présumées
- Rheumatoid Arthritis
- Spondyloarthritis
- Systemic Lupus Erythematosus
- Psoriasis
- Biothérapies non-anti-TNF
- Thérapies anti-TNF
- Essais cliniques
Synthèse automatique à partir des sources publiques (HAL, OpenAlex, theses.fr, ClinicalTrials.gov, FAI²R, ANS). Pas une évaluation clinique. Le médecin peut corriger via son compte.
Diplômes
🎓 DES & spécialité ordinale
- Rhumatologie (SM)
🎓 Diplômes
- DE Docteur en médecine
Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.
Direction de thèses
🎓 1 thèse dirigéeSource theses.fr — signal de direction d'équipe / statut PU-PH (à confirmer via le site universitaire).
Activité de recherche & publications
Source : bases de données publiques (OpenAlex, PubMed).
h-index
54
h articles cités ≥ h fois chacun. Un h de 54 = 54 publications avec 54+ citations.
Citations
10 930
Publications
363
i10-index
147
Thématiques principales
- Rheumatoid Arthritis Research and Therapies ×219
- Spondyloarthritis Studies and Treatments ×96
- Systemic Lupus Erythematosus Research ×59
- Autoimmune and Inflammatory Disorders Research ×48
- Psoriasis: Treatment and Pathogenesis ×31
Affiliations FR : Université Toulouse III - Paul Sabatier · Inserm · Université Fédérale de Toulouse Midi-Pyrénées
Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.
Bibliographie
Evidence for Pro-Inflammatory Activity of LTα3 on Macrophages: Significance for Experimental Arthritis and for Therapeutic Switching in Rheumatoid Arthritis Patients
2025ArticleInternational Journal of Molecular Sciences
Predicting Clinical Response to Monoclonal TNF Inhibitors in Rheumatoid Arthritis: A Transcriptomic Approach Based on Transmembrane TNF Reverse Signaling and Nrf2 Activation
2025ArticleDiagnostics
Do SMS/e-mail reminders increase influenza vaccination of rheumatoid arthritis patients under anti-TNF: a nested randomized controlled trial in the ART e-cohort
2024ArticleRheumatology
Changes in etanercept and adalimumab biosimilar prescriptions for the initial treatment of rheumatoid arthritis in France: Data from the ART-SFR Registry
2022ArticleJoint Bone Spine
Association Between Tumor Necrosis Factor Inhibitors and the Risk of Hospitalization or Death Among Patients With Immune-Mediated Inflammatory Disease and COVID-19
2021ArticleJAMA Network Open
Evidence for tmTNF reverse signaling in vivo
2021ArticleiScience
Prise en charge des patients atteints de maladies rhumatismales pendant la pandémie de COVID-19 : la Société française de rhumatologie répond aux questions fréquentes posées jusqu’en mai 2020
2021ArticleRevue du Rhumatisme
Current Favourable 10-Year Outcome of Patients with Early Rheumatoid Arthritis: Data from the ESPOIR Cohort
2021ArticleRheumatology
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
Lieu de consultation
CH JP CASSABEL CASTELNAUDARY
19 Avenue MONSEIGNEUR DE LANGLE, 11400 Castelnaudary
Tarifs & secteur de conventionnement
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Prendre rendez-vous & contact
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Top publications · les plus citées
- 2Effectiveness of Exercise Programs in Ankylosing Spondylitis: A Meta-Analysis of Randomized Controlled Trials
Archives of physical medicine and rehabilitation · 2018
📚 76 citations🎯 RCR 4.74Top 8% NIH - 3Update of French society for rheumatology recommendations for managing rheumatoid arthritis
Joint bone spine · 2019
Publications scientifiques (50) — classées par pathologie
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Transversal24
▼
Transversal24
▼- Predicting Clinical Response to Monoclonal TNF Inhibitors in Rheumatoid Arthritis: A Transcriptomic Approach Based on Transmembrane TNF Reverse Signaling and Nrf2 Activation
Diagnostics (Basel, Switzerland) · 2025 · Journal Article
Diallo K, Degboé Y, Baron M, Bellin-Robert A, et al.
📚 3 cit. - Evidence for Pro-Inflammatory Activity of LTα3 on Macrophages: Significance for Experimental Arthritis and for Therapeutic Switching in Rheumatoid Arthritis Patients
International journal of molecular sciences · 2025 · Journal Article
Benezech A, Gottenberg JE, Degboé Y, Kruglov A, et al.
- Serum Fatty Acid Profiles Are Associated with Disease Activity in Early Rheumatoid Arthritis: Results from the ESPOIR Cohort
Nutrients · 2022 · Journal Article
Sigaux J, Bellicha A, Buscail C, Julia C, et al.
📚 6 cit. - [JAK inhibitors in rheumatology]
La Revue du praticien · 2022 · Journal Article
Cantagrel A
- Evidence for tmTNF reverse signaling in vivo: Implications for an arginase-1-mediated therapeutic effect of TNF inhibitors during inflammation
iScience · 2021 · Journal Article
Diallo K, Simons N, Sayegh S, Baron M, et al.
📚 10 cit. - Prise en charge des patients atteints de maladies rhumatismales pendant la pandémie de COVID-19 : la Société française de rhumatologie répond aux questions fréquentes posées jusqu’en mai 2020
Revue du rhumatisme (Ed. francaise : 1993) · 2021 · Journal Article
Richez C, Flipo RM, Berenbaum F, Cantagrel A, et al.
- Cytomegalovirus infection: friend or foe in rheumatoid arthritis?
Arthritis research & therapy · 2021 · Journal Article
Davignon JL, Combe B, Cantagrel A
📚 11 cit. - Current favourable 10-year outcome of patients with early rheumatoid arthritis: data from the ESPOIR cohort
Rheumatology (Oxford, England) · 2021 · Journal Article
Combe B, Rincheval N, Berenbaum F, Boumier P, et al.
📚 20 cit.🎯 RCR 1.70🔬→🩺 Translationnel - Association Between Tumor Necrosis Factor Inhibitors and the Risk of Hospitalization or Death Among Patients With Immune-Mediated Inflammatory Disease and COVID-19
JAMA network open · 2021 · Journal Article
Izadi Z, Brenner EJ, Mahil SK, Dand N, et al.
📚 98 cit.🎯 RCR 5.12🔬→🩺 Translationnel - [Management of toxicities of BRAF inhibitors and MEK inhibitors in advanced melanoma]
Bulletin du cancer · 2021 · Journal Article
Sibaud V, Baric L, Cantagrel A, Di Palma M, et al.
📚 4 cit. - Early-onset granulomatous arthritis, uveitis and skin rash: characterization of skin involvement in Blau syndrome
Journal of the European Academy of Dermatology and Venereology : JEADV · 2020 · Journal Article
Poline J, Fogel O, Pajot C, Miceli-Richard C, et al.
📚 27 cit.🎯 RCR 2.10 - Managing patients with rheumatic diseases during the COVID-19 pandemic: The French Society of Rheumatology answers to most frequently asked questions up to May 2020
Joint bone spine · 2020 · Journal Article
Richez C, Flipo RM, Berenbaum F, Cantagrel A, et al.
📚 16 cit. - Part of pain labelled neuropathic in rheumatic disease might be rather nociplastic
RMD open · 2020 · Journal Article
Bailly F, Cantagrel A, Bertin P, Perrot S, et al.
📚 55 cit.🎯 RCR 4.03🔬→🩺 Translationnel - Outcomes and Findings of the International Rheumatoid Arthritis (RA) BIODAM Cohort for Validation of Soluble Biomarkers in RA
The Journal of rheumatology · 2020 · Journal Article
Maksymowych WP, FitzGerald O, Østergaard M, Homik J, et al.
📚 3 cit. - Inhibition of Osteoclastogenesis by the RNA-Binding Protein QKI5: a Novel Approach to Protect from Bone Resorption
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2020 · Journal Article
Rauwel B, Degboé Y, Diallo K, Sayegh S, et al.
📚 13 cit. - Reduced progression of bone erosion in cytomegalovirus seropositive rheumatoid arthritis patients
Arthritis research & therapy · 2020 · Journal Article
Rauwel B, Degboé Y, Nigon D, Boyer JF, et al.
📚 5 cit. - Characteristics and clinical outcomes after treatment of a national cohort of PCR-positive Lyme arthritis
Seminars in arthritis and rheumatism · 2019 · Journal Article
Grillon A, Scherlinger M, Boyer PH, De Martino S, et al.
📚 28 cit.🎯 RCR 1.83🔬→🩺 Translationnel - Corrigendum: Rheumatoid Synovial Fluids Regulate the Immunomodulatory Potential of Adipose-Derived Mesenchymal Stem Cells Through a TNF/NF-κB-Dependent Mechanism
Frontiers in immunology · 2019 · Published Erratum
Sayegh S, El Atat O, Diallo K, Rauwel B, et al.
📚 2 cit. - Predictors of good response to conventional synthetic DMARDs in early seronegative rheumatoid arthritis: data from the ESPOIR cohort
Arthritis research & therapy · 2019 · Journal Article
Lukas C, Mary J, Debandt M, Daïen C, et al.
📚 17 cit.🩺 Clinique - Rheumatoid Synovial Fluids Regulate the Immunomodulatory Potential of Adipose-Derived Mesenchymal Stem Cells Through a TNF/NF-κB-Dependent Mechanism
Frontiers in immunology · 2019 · Journal Article
Sayegh S, El Atat O, Diallo K, Rauwel B, et al.
📚 43 cit.🎯 RCR 2.33 - Update of French society for rheumatology recommendations for managing rheumatoid arthritis
Joint bone spine · 2019 · Journal Article
Daien C, Hua C, Gaujoux-Viala C, Cantagrel A, et al.
📚 75 cit.🎯 RCR 4.76🔬→🩺 Translationnel - Association between IL23R and ERAP1 polymorphisms and sacroiliac or spinal MRI inflammation in spondyloarthritis: DESIR cohort data
Arthritis research & therapy · 2019 · Clinical Trial
Ruyssen-Witrand A, Luxembourger C, Cantagrel A, Nigon D, et al.
📚 14 cit.🩺 Clinique - Psoriatic arthritis screening by the dermatologist: development and first validation of the 'PURE-4 scale'
Journal of the European Academy of Dermatology and Venereology : JEADV · 2018 · Journal Article
Audureau E, Roux F, Lons Danic D, Bagot M, et al.
📚 30 cit.🎯 RCR 1.83🔬→🩺 Translationnel - Infectious risk associated to orthopaedic surgery for rheumatoid arthritis patients treated by anti-TNFalpha
Joint bone spine · 2017 · Journal Article
Mabille C, Degboe Y, Constantin A, Barnetche T, et al.
📚 24 cit.🎯 RCR 1.36🔬→🩺 Translationnel
Biothérapies non-anti-TNF8
▼
Biothérapies non-anti-TNF8
▼- Two-year abatacept retention rate in clinical practice in the French ACTION cohort
Joint bone spine · 2019 · Journal Article
Mariette X, Schaeverbeke T, Gaudin P, Chartier M, et al.
📚 5 cit.🩺 Clinique - A single nucleotide polymorphism of IL6-receptor is associated with response to tocilizumab in rheumatoid arthritis patients
The pharmacogenomics journal · 2019 · Journal Article
Luxembourger C, Ruyssen-Witrand A, Ladhari C, Rittore C, et al.
📚 23 cit.🎯 RCR 1.20🔬→🩺 Translationnel - Serious infusion-related reaction after rituximab, abatacept and tocilizumab in rheumatoid arthritis: prospective registry data
Rheumatology (Oxford, England) · 2018 · Journal Article
Salmon JH, Perotin JM, Morel J, Dramé M, et al.
📚 23 cit.🎯 RCR 1.37🔬→🩺 Translationnel - Real-world predictors of 12-month intravenous abatacept retention in patients with rheumatoid arthritis in the ACTION observational study
RMD open · 2017 · Journal Article
Alten R, Mariette X, Lorenz HM, Galeazzi M, et al.
📚 20 cit.🔬→🩺 Translationnel - Impact of gender on the response and tolerance to abatacept in patients with rheumatoid arthritis: results from the 'ORA' registry
RMD open · 2017 · Journal Article
Nourisson C, Soubrier M, Mulliez A, Baillet A, et al.
📚 13 cit.🔬→🩺 Translationnel - The effect of body mass index on clinical response to abatacept as a first-line biologic for rheumatoid arthritis: 6-month results from the 2-year, observational, prospective ACTION study
Joint bone spine · 2017 · Journal Article
Mariette X, Alten R, Nüßlein HG, Galeazzi M, et al.
📚 14 cit.🩺 Clinique - A rare case of rheumatoid pachyleptomeningitis successfully treated with rituximab
Rheumatology (Oxford, England) · 2017 · Case Reports
Degboé Y, Fajadet B, Laurent C, Cantagrel A, et al.
📚 9 cit. - Safety of surgery in patients with rheumatoid arthritis treated by abatacept: data from the French Orencia in Rheumatoid Arthritis Registry
Rheumatology (Oxford, England) · 2017 · Journal Article
Latourte A, Gottenberg JE, Luxembourger C, Pane I, et al.
📚 11 cit.🩺 Clinique
Essai clinique4
▼
Essai clinique4
▼- The effect of periodontal treatment on patients with rheumatoid arthritis: The ESPERA randomised controlled trial
Joint bone spine · 2019 · Journal Article
Monsarrat P, Fernandez de Grado G, Constantin A, Willmann C, et al.
📚 35 cit.🎯 RCR 2.28🩺 Clinique - Short-term risk of major adverse cardiovascular events or congestive heart failure in patients with psoriatic arthritis or psoriasis initiating a biological therapy: a meta-analysis of randomised controlled trials
RMD open · 2019 · Journal Article
Champs B, Degboé Y, Barnetche T, Cantagrel A, et al.
📚 33 cit.🎯 RCR 1.76🔬→🩺 Translationnel - An e-health interactive self-assessment website (Sanoia(®)) in rheumatoid arthritis. A 12-month randomized controlled trial in 320 patients
Joint bone spine · 2018 · Journal Article
Gossec L, Cantagrel A, Soubrier M, Berthelot JM, et al.
📚 40 cit.🎯 RCR 2.72🩺 Clinique - Effectiveness of Exercise Programs in Ankylosing Spondylitis: A Meta-Analysis of Randomized Controlled Trials
Archives of physical medicine and rehabilitation · 2018 · Journal Article
Pécourneau V, Degboé Y, Barnetche T, Cantagrel A, et al.
📚 76 cit.🎯 RCR 4.74🔬→🩺 Translationnel
Revue / méta-analyse4
▼
Revue / méta-analyse4
▼- Short-term risk of major adverse cardiovascular events or congestive heart failure in patients with psoriatic arthritis or psoriasis initiating a biological therapy: a meta-analysis of randomised controlled trials
RMD open · 2019 · Journal Article
Champs B, Degboé Y, Barnetche T, Cantagrel A, et al.
📚 33 cit.🎯 RCR 1.76🔬→🩺 Translationnel - Risk of losing remission, low disease activity or radiographic progression in case of bDMARD discontinuation or tapering in rheumatoid arthritis: systematic analysis of the literature and meta-analysis
Annals of the rheumatic diseases · 2018 · Journal Article
Henaux S, Ruyssen-Witrand A, Cantagrel A, Barnetche T, et al.
📚 49 cit.🎯 RCR 2.37🔬→🩺 Translationnel - Anti-citrullinated peptides antibodies in systemic sclerosis: Meta-analysis of frequency and meaning
Joint bone spine · 2018 · Journal Article
Laustriat G, Ruyssen-Witrand A, Constantin A, Barnetche T, et al.
📚 14 cit.🔬→🩺 Translationnel - Effectiveness of Exercise Programs in Ankylosing Spondylitis: A Meta-Analysis of Randomized Controlled Trials
Archives of physical medicine and rehabilitation · 2018 · Journal Article
Pécourneau V, Degboé Y, Barnetche T, Cantagrel A, et al.
📚 76 cit.🎯 RCR 4.74🔬→🩺 Translationnel
Anti-TNF3
▼
Anti-TNF3
▼- Real-World Effectiveness and Safety of Infliximab Biosimilar CT-P13 for Rheumatic Diseases: A National Observational Cohort Study (ReFLECT)
Advances in therapy · 2025 · Journal Article
Marotte H, Cantagrel A, Coury F, Schaeverbeke T, et al.
📚 2 cit.🩺 Clinique - Changes in etanercept and adalimumab biosimilar prescriptions for the initial treatment of rheumatoid arthritis in France: Data from the ART-SFR Registry
Joint bone spine · 2022 · Letter
Ruyssen-Witrand A, Boudali Y, Pane I, Cantagrel A, et al.
📚 2 cit. - BENEFIT: real-world effectiveness of SB4 after transition from reference etanercept in rheumatoid arthritis and axial spondyloarthritis
Clinical and experimental rheumatology · 2021 · Journal Article
Selmi C, Krüger K, Cantagrel A, Abad Hernández MA, et al.
📚 10 cit.🔬→🩺 Translationnel
Stratégie thérapeutique3
▼
Stratégie thérapeutique3
▼- Stricter treat-to-target in RA does not result in less radiographic progression: a longitudinal analysis in RA BIODAM
Rheumatology (Oxford, England) · 2023 · Journal Article
Ramiro S, Landewé R, van der Heijde D, Sepriano A, et al.
📚 10 cit.🎯 RCR 1.82🔬→🩺 Translationnel - Adherence to Treat-to-target Management in Rheumatoid Arthritis and Associated Factors: Data from the International RA BIODAM Cohort
The Journal of rheumatology · 2020 · Clinical Trial
Sepriano A, Ramiro S, FitzGerald O, Østergaard M, et al.
📚 19 cit.🎯 RCR 1.29🩺 Clinique - Is treat-to-target really working in rheumatoid arthritis? a longitudinal analysis of a cohort of patients treated in daily practice (RA BIODAM)
Annals of the rheumatic diseases · 2020 · Journal Article
Ramiro S, Landewé RB, van der Heijde D, Sepriano A, et al.
📚 51 cit.🎯 RCR 3.46🔬→🩺 Translationnel
Spondyloarthrite2
▼
Spondyloarthrite2
▼- Biological DMARD efficacy in psoriatic arthritis: a systematic literature review and meta-analysis on articular, enthesitis, dactylitis, skin and functional outcomes
Clinical and experimental rheumatology · 2020 · Journal Article
Simons N, Degboé Y, Barnetche T, Cantagrel A, et al.
📚 18 cit.🎯 RCR 1.15🔬→🩺 Translationnel - Relationships between ultrasound enthesitis, disease activity and axial radiographic structural changes in patients with early spondyloarthritis: data from DESIR cohort
RMD open · 2017 · Journal Article
Ruyssen-Witrand A, Jamard B, Cantagrel A, Nigon D, et al.
📚 22 cit.🎯 RCR 1.30🔬→🩺 Translationnel
Épidémiologie & registres1
▼
Épidémiologie & registres1
▼- Chronic Hepatitis E in Rheumatology and Internal Medicine Patients: A Retrospective Multicenter European Cohort Study
Viruses · 2019 · Journal Article
Pischke S, Peron JM, von Wulffen M, von Felden J, et al.
📚 32 cit.🎯 RCR 2.12🩺 Clinique
Lombalgie1
▼
Lombalgie1
▼- Prevalence of inflammatory posterior arch abnormalities on lumbar spine MRI in spondyloarthritis patients compared with low back pain patients
European radiology · 2019 · Comparative Study
Braun H, Geniez C, Degboe Y, Constantin A, et al.
📚 7 cit.
Pharmacovigilance1
▼
Pharmacovigilance1
▼- Comparative Efficacy and Safety of Anakinra and Canakinumab in Patients With VEXAS Syndrome: An International Multicenter Study
Arthritis & rheumatology (Hoboken, N.J.) · 2026 · Journal Article
Eviatar T, Capelusnik D, Campochiaro C, Lacombe V, et al.
📚 5 cit.🎯 RCR 5.00
Revue générale1
▼
Revue générale1
▼- Modulation of T-cell responses by anti-tumor necrosis factor treatments in rheumatoid arthritis: a review
Arthritis research & therapy · 2018 · Journal Article
Davignon JL, Rauwel B, Degboé Y, Constantin A, et al.
📚 47 cit.🎯 RCR 1.85🔬→🩺 Translationnel
Vraie vie / RWE1
▼
Vraie vie / RWE1
▼- Effectiveness of Exercise Programs in Ankylosing Spondylitis: A Meta-Analysis of Randomized Controlled Trials
Archives of physical medicine and rehabilitation · 2018 · Journal Article
Pécourneau V, Degboé Y, Barnetche T, Cantagrel A, et al.
📚 76 cit.🎯 RCR 4.74🔬→🩺 Translationnel
Datasets & protocoles partagés
Regulation of CD36 membrane expression by tumor necrosis factor (TNF)α and adalimumab (Ada)
Image2011figshare<b>Copyright information:</b>Taken from "Tumor necrosis factor alpha and adalimumab differentially regulate CD36 expression in human monocytes"http://arthritis-research.com/content/9/2/R22Arthritis Research & Therapy
Mechanisms involved in the regulation of CD36 expression by adalimumab
Image2011figshare<b>Copyright information:</b>Taken from "Tumor necrosis factor alpha and adalimumab differentially regulate CD36 expression in human monocytes"http://arthritis-research.com/content/9/2/R22Arthritis Research & Therapy
Regulation of CD36 mRNA expression by tumor necrosis factor (TNF)α and adalimumab
Image2011figshare<b>Copyright information:</b>Taken from "Tumor necrosis factor alpha and adalimumab differentially regulate CD36 expression in human monocytes"http://arthritis-research.com/content/9/2/R22Arthritis Research & Therapy
Mechanisms involved in the regulation of CD36 expression by tumor necrosis factor (TNF)α
Image2011figshare<b>Copyright information:</b>Taken from "Tumor necrosis factor alpha and adalimumab differentially regulate CD36 expression in human monocytes"http://arthritis-research.com/content/9/2/R22Arthritis Research & Therapy
Anti-TNF certolizumab pegol induces antioxidant response in human monocytes via reverse signaling
Collection2016FigshareAbstract Background Anti TNF drugs have been widely used in rheumatoid arthritis (RA) but only 70 to 80 % of patients respond to this therapy. Exploring the mode of action of anti-TNF drugs remains important in order to
Regulation of CD36 membrane expression by tumor necrosis factor (TNF)α and adalimumab (Ada)
Image2011figshare<b>Copyright information:</b>Taken from "Tumor necrosis factor alpha and adalimumab differentially regulate CD36 expression in human monocytes"http://arthritis-research.com/content/9/2/R22Arthritis Research & Therapy
Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).