Docteur HELENE BRAUN

Bibliographie

• Prevalence of inflammatory posterior arch abnormalities on lumbar spine MRI in spondyloarthritis patients compared with low back pain patients

  2019

  ArticleEuropean Radiology

Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).

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• HOPITAL LA GRAVE CHU TOULOUSE

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Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Articles de presse (1)

Source : Google News (recherche par nom complet — homonymes possibles, vérifier le contenu).

• Toulouse. Une équipe mobile du CHU au chevet des EHPAD - ladepeche.fr

  📰 ladepeche.fr · 31/03/2020

  <a href="https://news.google.com/rss/articles/CBMilwFBVV95cUxNUUVIWTh0ZkJCRmFiaE4tWERXLUxFajZxSVlRbk1lZkJsRTVBVGtydThjOWxPQW91NWhYZHRQYTNYenhPcmNkb2U4OGJhZldKYmZGTFF6R2VqeHM5WkdHR0ZwZzhDME12bTdtQWIwYjdBRHhHTjdCZ2F4RElTUk93NVd5Nkl3ODM0elc5TXVUWVJqOUgzeHNj?oc=5" target="_blank">Toulouse. Une équipe mo

Top publications · les plus citées

• 1

  Diagnosis of osteoarthritis: imaging

  Bone · 2012

  📚 250 citations🎯 RCR 10.68Top 2% NIH🔓 Open Access
• 2

  The effect of platelet-rich plasma formulations and blood products on human synoviocytes: implications for intra-articular injury and therapy

  The American journal of sports medicine · 2014

  📚 220 citations🎯 RCR 10.57Top 2% NIH🔓 Open Access

  Lire l'abstract Crossref ↓

  Background: The effect of platelet-rich plasma (PRP) on chondrocytes has been studied in cell and tissue culture, but considerably less attention has been given to the effect of PRP on synoviocytes. Fibroblast-like synoviocytes (FLS) compose 80% of the normal human synovium and produce cytokines and matrix metalloproteinases that can mediate cartilage catabolism. Purpose: To compare the effects of leukocyte-rich PRP (LR-PRP), leukocyte-poor PRP (LP-PRP), red blood cell (RBC) concentrate, and platelet-poor plasma (PPP) on human FLS to determine whether leukocyte and erythrocyte concentrations of PRP formulations differentially affect the production of inflammatory mediators. Study Design: Controlled laboratory study. Methods: Peripheral blood was obtained from 4 donors and processed to create LR-PRP, LP-PRP, RBCs, and PPP. Human synoviocytes were cultured for 96 hours with the respective experimental conditions using standard laboratory conditions. Cell viability and inflammatory mediator production were then evaluated. Results: Treatment with LR-PRP resulted in significantly greater synoviocyte death (4.9% ± 3.1%) compared with LP-PRP (0.72% ± 0.70%; P = .035), phosphate-buffered saline (PBS) (0.39% ± 0.27%; P = .018), and PPP (0.26% ± 0.30%; P = .013). Synoviocytes treated with RBC concentrate demonstrated significantly greater cell death (12.5% ± 6.9%) compared with PBS ( P &lt; .001), PPP ( P &lt; .001), LP-PRP ( P &lt; .001), and LR-PRP (4.9% ± 3.1%; P &lt; .001). Interleukin (IL)–1β content was significantly higher in cultures treated with LR-PRP (1.53 ± 0.86 pg/mL) compared with those treated with PBS (0.22 ± 0.295 pg/mL; P &lt; .001), PPP (0.11 ± 0.179 pg/mL; P &lt; .001), and RBCs (0.64 ± 0.58 pg/mL; P = .001). IL-6 content was also higher with LR-PRP (32,097.82 ± 22,844.300 pg/mL) treatment in all other groups ( P &lt; .001). Tumor necrosis factor–α levels were greatest in LP-PRP (9.97 ± 3.110 pg/mL), and this was significantly greater compared with all other culture conditions ( P &lt; .001). Interferon-γ levels were greatest in RBCs (64.34 ± 22.987 pg/mL) and significantly greater than all other culture conditions ( P &lt; .001). Conclusion: Treatment of synovial cells with LR-PRP and RBCs resulted in significant cell death and proinflammatory mediator production. Clinical Relevance: Clinicians should consider using leukocyte-poor, RBC-free formulations of PRP when administering intra-articularly.

• 3

  EGFL7 ligates αvβ3 integrin to enhance vessel formation

  Blood · 2013

  📚 62 citations🎯 RCR 1.60

  Lire l'abstract Crossref ↓

  Key PointsEGFL7 promotes angiogenesis via its interaction with integrin αvβ3. EGFL7 is involved in physiological and pathological angiogenesis.

Publications scientifiques (18) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

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