Docteur Karima BOUSSOUALIM
4 publis sur 5 ans↘
✨ Profil synthétique
IA · 30/04/2026Le Docteur Karima BOUSSOUALIM est une rhumatologue hospitalière à Besançon, titulaire d'un DIU EA-PR/MAI. Ses recherches portent principalement sur les maladies rhumatismales, notamment la polyarthrite rhumatoïde, la santé osseuse et l'ostéoporose, ainsi que les spondylarthropathies. Elle a publié 20 articles et possède un h-index de 5.
Expertises présumées
- Polyarthrite rhumatoïde
- Ostéoporose
- Spondylarthropathie
- Thérapies ciblées pour les maladies osseuses
- Essais cliniques
- Recherche sur les csDMARDs
- Études de vie réelle (RWE)
Synthèse automatique à partir des sources publiques (HAL, OpenAlex, theses.fr, ClinicalTrials.gov, FAI²R, ANS). Pas une évaluation clinique. Le médecin peut corriger via son compte.
Diplômes
🎓 DES & spécialité ordinale
- DES Rhumatologie
- Rhumatologie (SM)
🏅 DU / DIU
- DIU Etudes approfondies polyarthrites-maladies
🎓 Diplômes
- DE Docteur en médecine
📝 Autres formations
- Cancérologie, option Traitements médicaux des cancers
- Cancérologie, option Traitements médicaux des cancers (DNQ)
Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.
🏆 Diplômes complémentaires reconnus
DIU EA-PR/MAIDIU
Le DIU rhumato généraliste de référence : polyarthrite rhumatoïde, spondyloarthrite, lupus, Sjögren, vascularites. Coordonné par la SFR.
Plusieurs universités, coordination Société Française de Rhumatologie (SFR)
Page d'information générale →
Activité de recherche & publications
Source : bases de données publiques (OpenAlex, PubMed).
h-index
5
h articles cités ≥ h fois chacun. Un h de 5 = 5 publications avec 5+ citations.
Citations
349
Publications
20
i10-index
3
Thématiques principales
- Rheumatoid Arthritis Research and Therapies ×6
- Bone health and osteoporosis research ×4
- Multiple Myeloma Research and Treatments ×4
- Spondyloarthritis Studies and Treatments ×3
- Bone and Joint Diseases ×3
Affiliations FR : Centre Hospitalier Universitaire de Saint-Étienne
Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.
Bibliographie
Proteomics analyses of human plasma reveal triosephosphate isomerase as a potential blood marker of methotrexate resistance in rheumatoid arthritis
2024ArticleRheumatology
Advanced practice nurse management in multiple myeloma treated with oral therapy
2023ArticleBulletin du Cancer
COVID-19 outcomes in patients with inflammatory rheumatic and musculoskeletal diseases treated with rituximab: a cohort study
2021ArticleThe Lancet Rheumatology
Severity of COVID-19 and survival in patients with rheumatic and inflammatory diseases: data from the French RMD COVID-19 cohort of 694 patients
2020ArticleAnnals of the Rheumatic Diseases
Infection cutanée à Mycobacterium chelonae chez un patient atteint de polyarthrite rhumatoïde sous glucocorticoïdes
2019ArticleRevue du Rhumatisme
Effect of heparin thromboprophylaxis on thrombin generation in multiple myeloma patients
2019ArticleBritish Journal of Haematology
Cutaneous Mycobacterium chelonae infection in a patient with rheumatoid arthritis treated with glucocorticoids
2019ArticleJoint Bone Spine
A 3-year back and forth between Modic type 1 and 2 on MRI in chronic low back pain
2019ArticleJoint Bone Spine
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
Lieu de consultation
MDPH DOUBS
13 Rue DE LA PREFECTURE, 25043 Besançon
☎ 0381259000Hospitalier
Tarifs & secteur de conventionnement
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Prendre rendez-vous & contact
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Top publications · les plus citées
- 1Evaluation of bone quality with trabecular bone score in active spondyloarthritis
Joint bone spine · 2018
📚 19 citations🎯 RCR 1.09 - 2Effectiveness of a nurse-led telephone follow-up in the therapeutic management of patients receiving oral antineoplastic agents: a randomized, multicenter controlled trial (ETICCO study)
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021
📚 13 citations🩺 Clinique - 3Proteomics analyses of human plasma reveal triosephosphate isomerase as a potential blood marker of methotrexate resistance in rheumatoid arthritis
Rheumatology (Oxford, England) · 2024
📚 4 citationsLire l'abstract Crossref ↓
Abstract Objective The objective of this study was to assess differentially expressed blood proteins between patients with active RA and patients in remission after MTX treatment, with the aim of identifying a biomarker of MTX resistance (MTXR). Methods Two populations of RA patients treated with a stable dose of s.c. MTX for at least 3 months were constituted according to the DAS28: remission (DAS28 < 2.6; n = 24) and active disease (DAS28 > 3.2; n = 32). The two groups of RA patients were homogeneous regarding their epidemiological characteristics, except for the duration of treatment, which was longer in the remission group. After collection of a blood sample, plasma protein digestion was performed, followed by untargeted proteomics analysis. Then, a targeted analysis was performed to confirm the results of the untargeted approach. Results Untargeted proteomics analysis revealed eight plasma proteins that were differentially expressed between the two groups of patients. Among them, triosephosphate isomerase (TPI-1) and glucose-6-phosphate isomerase (GPI), which are main actors in glycolysis, were found down-regulated in the active group. This result was confirmed for TPI-1 in the targeted proteomics analysis. Conclusion A first step was achieved in the search for biomarkers of MTXR, with the identification of two actors in glycolysis (TPI-1 and GPI). The next step will be to confirm these results in a larger cohort, including samples from treatment-naive patients, to assess the predictive potential of these protein markers.
Publications scientifiques (7) — classées par pathologie
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Transversal5
▼
Transversal5
▼- Advanced practice nurse management in multiple myeloma treated with oral therapy
Bulletin du cancer · 2023 · Journal Article
Sapet M, Migala C, Daguenet E, Collet P, et al.
📚 1 cit. - Second-generation hormonotherapy in prostate cancer and bone microenvironment
Endocrine-related cancer · 2021 · Journal Article
Bouleftour W, Boussoualim K, Sotton S, Vassal C, et al.
📚 4 cit.🔬→🩺 Translationnel - Effect of heparin thromboprophylaxis on thrombin generation in multiple myeloma patients
British journal of haematology · 2019 · Letter
Chalayer E, Tardy-Poncet B, Montmartin A, Boussoualim K, et al.
📚 4 cit.🔬→🩺 Translationnel - Cutaneous Mycobacterium chelonae infection in a patient with rheumatoid arthritis treated with glucocorticoids
Joint bone spine · 2019 · Case Reports
Mungroo M, Ojardias E, Amouzougan A, Boussoualim K, et al.
📚 1 cit. - Evaluation of bone quality with trabecular bone score in active spondyloarthritis
Joint bone spine · 2018 · Journal Article
Boussoualim K, Amouzougan A, Pallot-Prades B, Denarié D, et al.
📚 19 cit.🎯 RCR 1.09🔬→🩺 Translationnel
csDMARDs1
▼
csDMARDs1
▼- Proteomics analyses of human plasma reveal triosephosphate isomerase as a potential blood marker of methotrexate resistance in rheumatoid arthritis
Rheumatology (Oxford, England) · 2024 · Journal Article
Escal J, Neel T, Hodin S, Boussoualim K, et al.
📚 4 cit.🔬→🩺 Translationnel
Essai clinique1
▼
Essai clinique1
▼- Effectiveness of a nurse-led telephone follow-up in the therapeutic management of patients receiving oral antineoplastic agents: a randomized, multicenter controlled trial (ETICCO study)
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021 · Journal Article
Bouleftour W, Muron T, Guillot A, Tinquaut F, et al.
📚 13 cit.🩺 Clinique
Vraie vie / RWE1
▼
Vraie vie / RWE1
▼- Effectiveness of a nurse-led telephone follow-up in the therapeutic management of patients receiving oral antineoplastic agents: a randomized, multicenter controlled trial (ETICCO study)
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2021 · Journal Article
Bouleftour W, Muron T, Guillot A, Tinquaut F, et al.
📚 13 cit.🩺 Clinique
