Docteur Maxime AUROUX

Bibliographie

• PFMG2025–integrating genomic medicine into the national healthcare system in France

  2025

  ArticleThe Lancet Regional Health - Europe

• Evaluation of circulating microRNA signature in patients with erosive hand osteoarthritis: The HOAmiR study

  2024

  ArticleOsteoarthritis and Cartilage

• Association of circulating hsa-miRNAs with sarcopenia: the SarcoPhAge study

  2024

  ArticleAging Clinical and Experimental Research

• Réponse sérologique après vaccination contre le coronavirus chez les patients atteints de rhumatisme inflammatoire chronique traités par DMARDs : étude de cohorte et revue systématique avec méta-analyse

  2022

  ArticleRevue du Rhumatisme

Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).

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Prendre rendez-vous & contact

Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Vidéos & interventions (1)

Source YouTube · recherche par nom (homonymes possibles).

• 0:42

  Disussion de 10h20 avec Maxime AUROUX

  Semaine Rhumatologie Aix · 57 vues

Top publications · les plus citées

• 1

  Serological response to SARS-CoV-2 vaccination in patients with inflammatory rheumatic disease treated with disease modifying anti-rheumatic drugs: A cohort study and a meta-analysis

  Joint bone spine · 2022

  📚 11 citations🔓 Open Access
• 2

  Association of circulating hsa-miRNAs with sarcopenia: the SarcoPhAge study

  Aging clinical and experimental research · 2024

  📚 8 citations🎯 RCR 2.24Top 23% NIH🔓 Open Access📄 PDF gratuit ↗

  Lire l'abstract Crossref ↓

  Abstract Objective To identify a microRNA signature associated to sarcopenia in community-dwelling older adults form the SarcoPhAge cohort. Methods In a screening phase by next generation sequencing (NGS), we compared the hsa-miRome expression of 18 subjects with sarcopenia (79.6 ± 6.8 years, 9 men) and 19 healthy subjects without sarcopenia (77.1 ± 6 years, 9 men) at baseline. Thereafter, we have selected eight candidate hsa-miRNAs according to the NGS results and after a critical assessment of previous literature. In a validation phase and by real-time qPCR, we then analyzed the expression levels of these 8 hsa-miRNAs at baseline selecting 92 healthy subjects (74.2 ± 10 years) and 92 subjects with sarcopenia (75.3 ± 6.8 years). For both steps, the groups were matched for age and sex. Results In the validation phase, serum has-miRNA-133a-3p and has-miRNA-200a-3p were significantly decreased in the group with sarcopenia vs controls [RQ: relative quantification; median (interquartile range)]: −0.16 (−1.26/+0.90) vs +0.34 (−0.73/+1.33) (p < 0.01) and −0.26 (−1.07/+0.68) vs +0.27 (−0.55/+1.10) (p < 0.01) respectively. Has-miRNA-744-5p was decreased and has-miRNA-151a-3p was increased in the group with sarcopenia vs controls, but this barely reached significance: +0.16 (−1.34/+0.79) vs +0.44 (−0.31/+1.00) (p = 0.050) and +0.35 (−0.22/+0.90) vs +0.03 (−0.68/+0.75) (p = 0.054). Conclusion In subjects with sarcopenia, serum hsa-miRNA-133a-3p and hsa-miRNA-200a-3p expression were downregulated, consistent with their potential targets inhibiting muscle cells proliferation and differentiation.

• 3

  The disability associated with hand osteoarthritis is substantial in a cohort of post-menopausal women: the QUALYOR study

  Osteoarthritis and cartilage · 2022

  📚 7 citations

Publications scientifiques (11) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

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