Mme Docteur LAETITIA SPARSA

Bibliographie

• Individual and environmental determinants associated with longer times to access pediatric rheumatology centers for patients with juvenile idiopathic arthritis, a JIR cohort study

  2023

  ArticlePediatric Rheumatology

• Criteria Associated with Treatment Decisions in Juvenile Idiopathic Arthritis with a Focus on Ultrasonography: Results from the JIRECHO Cohort

  2022

  ArticleRheumatology and Therapy

• Gait and Axial Spondyloarthritis: Comparative Gait Analysis Study Using Foot-Worn Inertial Sensors

  2021

  ArticleAnnals of the Rheumatic Diseases

• L’alliance thérapeutique est associée à l’adhésion au traitement chez les enfants atteints d’arthrite juvénile idiopathique

  2021

  ArticleRevue du Rhumatisme

• Application of the OMERACT synovitis ultrasound scoring system in juvenile idiopathic arthritis: a multicenter reliability exercise

  2021

  ArticleRheumatology

• Therapeutic alliance is associated to treatment adherence in children with juvenile idiopathic arthritis

  2021

  ArticleJoint Bone Spine

• COVID-19 outcomes in patients with inflammatory rheumatic and musculoskeletal diseases treated with rituximab: a cohort study

  2021

  ArticleThe Lancet Rheumatology

• Efficacy of a tight-control and treat-to-target strategy in axial spondyloarthritis: results of the open-label, pragmatic, cluster-randomised TICOSPA trial

  2021

  ArticleAnnals of the Rheumatic Diseases

Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).

Localisation des cabinets

Adresses géocodées via la Base Adresse Nationale (api-adresse.data.gouv.fr). Précision indicative.

Lieux de consultation

• CABINET DU DOCTEUR LAETITIA SPARSA

  47 BOULEVARD ALFRED WALLACH, 68100 Mulhouse

  Libéral
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  📷 Street View ↗🗺️ Maps ↗OSM ↗

• INSTITUT MEDICO SPORTIF SUD ALSACE

  INSTITUT MEDICO SPORTIF SUD ALSACE — 5 RUE DES FRERES LUMIERE, 68200 Mulhouse

  Libéral
  © OpenStreetMap

  📷 Street View ↗🗺️ Maps ↗OSM ↗

• 48030125800020

  INSTITUT MEDICO SPORTIF SUD ALSACE 5 RUE DES FRERES LUMIERE, 68200 MULHOUSE

  Activité de soin et de pharmacie

Tarifs & secteur de conventionnement

Prendre rendez-vous & contact

Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Articles de presse (1)

Source : Google News (recherche par nom complet — homonymes possibles, vérifier le contenu).

• Santé. Une nouvelle spécialité au service pédiatrie du Hasenrain - L'Alsace

  📰 L'Alsace · 12/07/2012

  <a href="https://news.google.com/rss/articles/CBMiowFBVV95cUxQd1JfYlN2X1I1T1NqdmVMWFhLaVE5NXo0cVJ3Wk83VVdWclBfX0NLOVFIY0dIN0h6Q1pSVU1MMnZ2RHIteEtVaTg5RlY5cGZtQjBrdFNlOFVDaEpKT1FrSFBYVE5TUWNHcmdHUU82N29BX29NOGZGMUJIOTY5RldDN2hJSUV3ektIMU9vaHBzWFBvZ1U1Vi1LUDllbERkLWxsVG5F?oc=5" target="_blank">Santé.

Top publications · les plus citées

• 1

  Efficacy of a tight-control and treat-to-target strategy in axial spondyloarthritis: results of the open-label, pragmatic, cluster-randomised TICOSPA trial

  Annals of the rheumatic diseases · 2021

  📚 93 citations🎯 RCR 7.65Top 4% NIH🩺 Clinique🔓 Open Access📄 PDF gratuit ↗
• 2

  Evaluation of the impact of concomitant fibromyalgia on TNF alpha blockers' effectiveness in axial spondyloarthritis: results of a prospective, multicentre study

  Annals of the rheumatic diseases · 2018

  📚 82 citations🎯 RCR 4.61Top 9% NIH🩺 Clinique
• 3

  Innate immunity triggers IL-32 expression by fibroblast-like synoviocytes in rheumatoid arthritis

  Arthritis research & therapy · 2010

  📚 61 citations🎯 RCR 1.56🔓 Open Access📄 PDF gratuit ↗

  Lire l'abstract Crossref ↓

  Abstract Introduction Interleukin-32 (IL-32) is a recently described cytokine that is a strong inducer of pro-inflammatory cytokines such as tumor necrosis factor (TNF)-α, IL-1β, IL-6, and IL-8. The expression of this cytokine is highly increased in the rheumatoid synovium and correlated with the severity of joint inflammation. Little is known regarding the innate immune-related regulation of IL-32 by fibroblast-like synoviocytes (FLSs). We therefore investigated the effect of innate immune stimulation by ligands of Toll-like receptor (TLR)2, TLR3, and TLR4, and cytokines such as TNF-α and interferon (IFN)-γ, on IL-32 expression by FLSs. Methods FLSs were isolated from patients with rheumatoid arthritis (RA) according to the ACR criteria. Quantitative RT-PCR, confocal analysis, and ELISA were performed to evaluate IL-32 mRNA induction and IL-32 release by FLSs stimulated with TLR2 (BLP), TLR3 (poly I:C), and TLR4 (lipopolysaccharide) ligands, TNF-α and IFN-γ. Results TLR2, -3, and -4 ligands as well as IFN-γ and TNF-α induced IL-32 β, γ and δ mRNA expression by RA FLSs. Mature IL-32 was expressed intracellularly and released by cells stimulated with the various activators. The IL-32α isoform was expressed intracellularly in response to TNF-α and poly I:C and not released in culture supernatants. Stimulation of FLS with TNF-α, BLP, lipopolysaccharide, or poly I:C concomitant with IFN-γ increased IL-32 expression compared with stimulation with IFN-γ alone. Conclusions IL-32 synthesis by FLSs is tightly regulated by innate immunity in rheumatoid arthritis. Thus TNF-α, IFN-γ, double-strand RNA, hyaluronic acid, or other damage-associated molecular patterns (DAMPs), highly secreted in synovial tissues of RA patients, might trigger IL-32 secretion by FLSs. IL-32 might therefore represent a relevant therapeutic target in RA.

Publications scientifiques (19) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

Datasets & protocoles partagés

• Individual and environmental determinants associated with longer times to access pediatric rheumatology centers for patients with juvenile idiopathic arthritis, a JIR cohort study

  Collection2023figshare

  Abstract Background Despite guidelines, poor access to appropriate care for juvenile idiopathic arthritis (JIA) patients remains a global issue. Prompt referral to a pediatric rheumatology (PR) center and effective care

• Individual and environmental determinants associated with longer times to access pediatric rheumatology centers for patients with juvenile idiopathic arthritis, a JIR cohort study

  Collection2023figshare

  Abstract Background Despite guidelines, poor access to appropriate care for juvenile idiopathic arthritis (JIA) patients remains a global issue. Prompt referral to a pediatric rheumatology (PR) center and effective care

Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).

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