Docteur ANGELA-RAMONA FEKETE-POPOVICI
Diplômes
🎓 DES & spécialité ordinale
- Rhumatologie (SM)
🎓 Diplômes
- Diplôme éq d'un pays de l'EEE profession Médecin
📝 Autres formations
- DEES Rhumatologie
Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.
Localisation
Adresses géocodées via la Base Adresse Nationale (api-adresse.data.gouv.fr). Précision indicative.
Lieux de consultation
HOPITAL LOUIS PASTEUR
39 Avenue DE LA LIBERTE, 68024 Colmar
☎ 0389124000HospitalierCABINET DU DR ANGELA-RAMONA FEKETE-POPOVICI
30 RUE DE THANN, 68000 Colmar
Libéral
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Tarifs & secteur de conventionnement
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Prendre rendez-vous & contact
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Top publications · les plus citées
- 1miR-125b is downregulated in systemic lupus erythematosus patients and inhibits autophagy by targeting UVRAG
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2018
📚 36 citations🎯 RCR 1.54 - 2Irisin ameliorates bone loss in ovariectomized mice
Climacteric : the journal of the International Menopause Society · 2020
📚 34 citations🎯 RCR 2.29Top 23% NIH - 3Role and Therapeutic Potential for Targeting Fibroblast Growth Factor 10/FGFR1 in Relapsed Rheumatoid Arthritis
Arthritis & rheumatology (Hoboken, N.J.) · 2024
Lire l'abstract Crossref ↓
ObjectiveFibroblast‐like synoviocytes (FLSs) contribute to inflammation and joint damage in rheumatoid arthritis (RA). However, the regulatory mechanisms of FLSs in relapse and remission of RA remain unknown. Identifying FLS heterogeneity and their underlying pathogenic roles may lead to discovering novel disease‐modifying antirheumatic drugs.MethodsCombining single‐cell RNA sequencing (scRNA‐seq) and spatial transcriptomics, we sequenced six matched synovial tissue samples from three patients with relapse RA and three patients in remission. We analyzed the differences in the transcriptomes of the FLS subsets between the relapse and remitted phases. We validated several key signaling pathways using quantitative real‐time PCR (qPCR) and multiplex immunohistochemistry (mIHC). We further targeted the critical signals in vitro and in vivo using the collagen‐induced arthritis (CIA) model in rats.ResultsLining and sublining FLS subsets were identified using scRNA‐seq. Differential analyses indicated that the fibroblast growth factor (FGF) pathway was highly activated in the lining FLSs from patients with relapse RA for which mIHC confirmed the increased expression of FGF10. Although the type I interferon pathway was also activated in the lining FLSs, in vitro stimulation experiment suggested that it was independent of the FGF10 pathway. FGF10 knockdown by small interfering RNA in FLSs significantly reduced the expression of receptor activator of NF‐κB ligand. Moreover, recombinant FGF10 protein enhanced bone erosion in the primary human‐derived pannus cell culture, whereas the FGF receptor (FGFR) 1 inhibitor attenuated this process. Finally, administering an FGFR1 inhibitor displayed a therapeutic effect in a CIA rat model.ConclusionThe FGF pathway is a critical signaling pathway in relapse RA. Targeted tissue‐specific inhibition of FGF10/FGFR1 may provide new opportunities to treat patients with relapse RA.
Publications scientifiques (45) — classées par pathologie
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Transversal33
▼
Transversal33
▼- Correction: Targeting lactate metabolism to restore immune homeostasis: a precision therapeutic paradigm for rheumatoid arthritis
Frontiers in immunology · 2026 · Published Erratum
Zheng L, A X, Ma S, Xu B, et al.
- Correction: Targeting lactate metabolism to restore immune homeostasis: a precision therapeutic paradigm for rheumatoid arthritis
Frontiers in immunology · 2026 · Published Erratum
Zheng L, A X, Ma S, Xu B, et al.
- Correction: Integrative multi-omics analyses identify PKD1 and SLC2A4 as genetically supported glycolysis-related candidate genes for rheumatoid arthritis
Frontiers in immunology · 2026 · Journal Article
A X, Xin P, Zheng L, Xu B, et al.
- Integrative multi-omics analyses identify PKD1 and SLC2A4 as genetically supported glycolysis-related candidate genes for rheumatoid arthritis
Frontiers in immunology · 2025 · Journal Article
A X, Xin P, Zheng L, Xu B, et al.
📚 1 cit. - Targeting lactate metabolism to restore immune homeostasis: a precision therapeutic paradigm for rheumatoid arthritis
Frontiers in immunology · 2025 · Journal Article
Zheng L, A X, Ma S, Xu B, et al.
📚 1 cit. - Juanbi Qianggu Formula inhibits fibroblast-like synovicytes activation via repressing LncRNA ITSN1-2 to promote RIP2 K48 ubiquitination
Chinese medicine · 2025 · Journal Article
Bian Y, Li F, A X, Xiang Z, et al.
📚 1 cit. - Computational insights and study of drugs for dry eye disease through QSPR and MCDM approaches using topological indices
Scientific reports · 2025 · Journal Article
M C S, B K, A U, K C S
- Hands-free radiographic canine hip distraction view with applied force monitoring
BMC veterinary research · 2025 · Journal Article
A S, S AP, J M, P C, et al.
- Evaluation and Analysis of Outcomes of Unicondylar Knee Arthroplasty in Unicompartmental Knee Osteoarthritis
Cureus · 2025 · Journal Article
N M, A NT, Muruganandan R, Vellingiri K
📚 1 cit. - Modulation of morphine antinociceptive and rewarding effect by mirtazapine in an animal model of osteoarthritic pain
European journal of pharmacology · 2025 · Journal Article
N P, M M G, C RR, D P, et al.
📚 2 cit. - Protein Nano Coop Complexes Promote Fracture Healing and Bone Regeneration in a Zebrafish Osteoporosis Model
Biomacromolecules · 2024 · Journal Article
Kabir A, B M, A N, Selvaraj V, et al.
📚 2 cit. - Inflammation dynamically regulates steroid hormone metabolism and action within macrophages in rheumatoid arthritis
Journal of autoimmunity · 2024 · Journal Article
Martin CS, Crastin A, Sagmeister MS, Kalirai MS, et al.
📚 14 cit.🎯 RCR 3.73 - Hemisphere lateralization of graph theoretical network in end-stage knee osteoarthritis patients
Brain research bulletin · 2024 · Journal Article
Kang B, Ma J, Shen J, Zhao C, et al.
📚 1 cit. - Unravelling the Relacatib activity against the CTSK proteins causing pycnodysostosis: a molecular docking and dynamics approach
Journal of biomolecular structure & dynamics · 2024 · Journal Article
Kannan P, A HB, N MP, D TK, et al.
📚 2 cit. - An Unusual Case of Peripheral Nerve Vasculitis
Case reports in rheumatology · 2024 · Case Reports
Wang S, A A, Feinstein D, Traisak P, et al.
- Role and Therapeutic Potential for Targeting Fibroblast Growth Factor 10/FGFR1 in Relapsed Rheumatoid Arthritis
Arthritis & rheumatology (Hoboken, N.J.) · 2024 · Journal Article
Meng X, Chen Z, Li T, Nie Z, et al.
📚 31 cit.🎯 RCR 5.26 - [Diagnostic value of anti-Sa antibody and anti-carbamylated protein antibody for rheumatoid arthritis]
Zhonghua yi xue za zhi · 2023 · English Abstract
Lyu YK, Li ZA, A XR, Ma JD, et al.
📚 1 cit. - Study on the clinical efficacy of Mongolian medicine in the treatment of osteoarthritis
American journal of translational research · 2023 · Journal Article
A R, Mu R, Wu Q, Ga L, et al.
- Effect of Multimorbidity on Fragility Fractures in Community-Dwelling Older Adults: Shimane CoHRE Study
Journal of clinical medicine · 2021 · Journal Article
A G, Yano S, Sheik AM, Yu A, et al.
📚 18 cit.🎯 RCR 1.57 - The role of pain and walking difficulties in shaping willingness to undergo joint surgery for osteoarthritis: Data from the Swedish BOA register
Osteoarthritis and cartilage open · 2021 · Journal Article
A D, A T, T J, O R, et al.
📚 8 cit. - Comparative Evaluation of Carbon Reinforced Polyetherketone Acetabular Cup using Finite Element Analysis
Journal of biomedical physics & engineering · 2020 · Journal Article
A A, R N, G C
- Irisin ameliorates bone loss in ovariectomized mice
Climacteric : the journal of the International Menopause Society · 2020 · Journal Article
Luo Y, Ma Y, Qiao X, Zeng R, et al.
📚 34 cit.🎯 RCR 2.29 - Evaluation of anti-arthritic potential of Trigonella foenum graecum L. (Fenugreek) mucilage against rheumatoid arthritis
Prostaglandins & other lipid mediators · 2018 · Journal Article
G S, G L S, Pushpan CK, Nambisan B, et al.
📚 14 cit. - Betulinic acid and fluvastatin exhibits synergistic effect on toll-like receptor-4 mediated anti-atherogenic mechanism in type II collagen induced arthritis
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2017 · Journal Article
Mathew LE, Rajagopal V, A H
📚 11 cit. - A Technical Note for Extracting an Incarcerated Femoral Kuntscher Nail
Journal of orthopaedic case reports · 2016 · Case Reports
R M, D VV, A LG, P G, et al.
📚 10 cit. - Refixation of Osteochondral Fractures by an Ultrasound-Activated Pin System - An Ovine In Vivo Examination Using CT and Scanning Electron Microscope
The open orthopaedics journal · 2015 · Journal Article
H N, A P S, S B, A U, et al.
- A positive association between foot posture index and medial compartment knee osteoarthritis in moroccan people
The open rheumatology journal · 2014 · Journal Article
F E A, N K, H A, F L, et al.
📚 23 cit.🎯 RCR 1.32 - Metabonomic profiling in studying anti-osteoporosis effects of strontium fructose 1,6-diphosphate on estrogen deficiency-induced osteoporosis in rats by GC/TOF-MS
European journal of pharmacology · 2013 · Journal Article
Ma B, Li X, Zhang Q, Wu D, et al.
📚 28 cit.🎯 RCR 1.17 - Metabolomic profiles delineate signature metabolic shifts during estrogen deficiency-induced bone loss in rat by GC-TOF/MS
PloS one · 2013 · Journal Article
Ma B, Liu J, Zhang Q, Ying H, et al.
📚 31 cit.🎯 RCR 1.13 - Pulmonary function test: its correlation with pulmonary high-resolution computed tomography in patients with rheumatoid arthritis
Rheumatology international · 2012 · Journal Article
Leonel D, Lucia C, A M, Martha-Alicia H, et al.
📚 13 cit.🔬→🩺 Translationnel - The future of rheumatoid arthritis and hand surgery - combining evolutionary pharmacology and surgical technique
The open orthopaedics journal · 2012 · Journal Article
M M, H G, S H, A J, et al.
📚 5 cit. - [Early clinical outcomes of fixed-bearing versus mobile-bearing total knee arthroplasty]
Zhonghua yi xue za zhi · 2011 · Comparative Study
Zeng Y, Cao L, Liu Y, Peng GF, et al.
📚 4 cit.🩺 Clinique - Expression of Retinoic Acid Receptor (RAR) α Protein in the Synovial Membrane from Patients with Osteoarthritis and Rheumatoid Arthritis
International journal of biomedical science : IJBS · 2007 · Journal Article
A Z, Cd K, Ad V, T K, et al.
📚 6 cit.
Qualité de vie / PROMs2
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Qualité de vie / PROMs2
▼- Comparison of Improvements in Quality of Life With Disease-Modifying Anti-rheumatic Drugs in Seropositive and Seronegative Rheumatoid Arthritis
Cureus · 2025 · Journal Article
Muraleedharan A, Chaubey S, A S, Yadav A
- [Regaining quality of life despite rheumatoid arthritis]
Revue de l'infirmiere · 2016 · English Abstract
A M
Arthrite juvénile1
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Arthrite juvénile1
▼- Hip denervation: an approach for relieving pain, restoring function, and reducing inflammation in juvenile idiopathic arthritis patients
Clinical rheumatology · 2025 · Journal Article
A K, M EA, M H, H A, et al.
🩺 Clinique
Biomarqueurs / Auto-Ac1
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Biomarqueurs / Auto-Ac1
▼- Plasma Proteomics Identifies Thousand-and-One-Amino Acid Kinase 3 as a Potential Biomarker of Rheumatoid Arthritis Activity and a Novel Therapeutic Target
Arthritis & rheumatology (Hoboken, N.J.) · 2026 · Journal Article
Xin P, Li W, A X, Shen J, et al.
Case report / série1
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Case report / série1
▼- Antibodies in Aseptic Meningitis of Connective Tissue Disorder: A Case Report
Cureus · 2024 · Case Reports
Ravichandran S, Kumar J, Chandrasekaran ND, Irfan S, et al.
csDMARDs1
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csDMARDs1
▼- The effect of JuanBiQiangGu granules in combination with methotrexate on joint inflammation in rheumatoid arthritis: a randomized controlled trial
Frontiers in pharmacology · 2023 · Journal Article
Ran L, Xu B, Han HH, Wang JY, et al.
📚 4 cit.
Épidémiologie & registres1
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Épidémiologie & registres1
▼- Prevalence of Metabolic Syndrome and Noncommunicable Disease Risk Factors in Andaman and Nicobar Islands, India, and Their Association With Ayurvedic Psychosomatic Constitution (Prakriti) and Socioeconomic Status: Protocol for a Cross-Sectional Study
JMIR research protocols · 2025 · Journal Article
M A, Ahmad A, A A, Raj LS, et al.
Essai clinique1
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Essai clinique1
▼- The Effectiveness of Tuina in Relieving Pain, Negative Emotions, and Disability in Knee Osteoarthritis: A Randomized Controlled Trial
Pain medicine (Malden, Mass.) · 2023 · Randomized Controlled Trial
Xu H, Zhao C, Guo G, Li Y, et al.
📚 30 cit.🎯 RCR 6.74🩺 Clinique
IRM ostéo-articulaire1
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IRM ostéo-articulaire1
▼- Altered brain activity in end-stage knee osteoarthritis revealed by resting-state functional magnetic resonance imaging
Brain and behavior · 2022 · Journal Article
Kang BX, Ma J, Shen J, Xu H, et al.
📚 22 cit.🎯 RCR 2.91🔬→🩺 Translationnel
Lupus1
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Lupus1
▼- miR-125b is downregulated in systemic lupus erythematosus patients and inhibits autophagy by targeting UVRAG
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2018 · Journal Article
Cao W, Qian G, Luo W, Liu X, et al.
📚 36 cit.🎯 RCR 1.54
Ostéoporose1
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Ostéoporose1
▼- Evaluation of clinical risk factors for osteoporotic fractures using the FRAX calculator among women in Armenia aged 40 and older
Archives of osteoporosis · 2025 · Journal Article
N BV, A MS, A DR, H SG, et al.
Vascularites des gros vaisseaux1
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Vascularites des gros vaisseaux1
▼- Ocular manifestations of Behcet's disease
Indian pediatrics · 2005 · Case Reports
A SE, Moses PD, George R
📚 3 cit.
Vraie vie / RWE1
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Vraie vie / RWE1
▼- The Effectiveness of Tuina in Relieving Pain, Negative Emotions, and Disability in Knee Osteoarthritis: A Randomized Controlled Trial
Pain medicine (Malden, Mass.) · 2023 · Randomized Controlled Trial
Xu H, Zhao C, Guo G, Li Y, et al.
📚 30 cit.🎯 RCR 6.74🩺 Clinique