Mme Docteur Carole DEVY-MOUCHES

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• CABINET DU DR CAROLE DEVY-MOUCHES

  1 AVENUE DE LA DIVISION LECLERC, 92290 Châtenay-Malabry

  ☎ 0146607430Libéral
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Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Top publications · les plus citées

• 1

  Genome-wide identification, evolutionary and expression analysis of the aspartic protease gene superfamily in grape

  BMC genomics · 2013

  📚 71 citations🎯 RCR 2.49Top 21% NIH🔓 Open Access📄 PDF gratuit ↗

  Lire l'abstract Crossref ↓

  Abstract Background Aspartic proteases (APs) are a large family of proteolytic enzymes found in almost all organisms. In plants, they are involved in many biological processes, such as senescence, stress responses, programmed cell death, and reproduction. Prior to the present study, no grape AP gene(s) had been reported, and their research on woody species was very limited. Results In this study, a total of 50 AP genes (VvAP) were identified in the grape genome, among which 30 contained the complete ASP domain. Synteny analysis within grape indicated that segmental and tandem duplication events contributed to the expansion of the grape AP family. Additional analysis between grape and Arabidopsis demonstrated that several grape AP genes were found in the corresponding syntenic blocks of Arabidopsis, suggesting that these genes arose before the divergence of grape and Arabidopsis. Phylogenetic relationships of the 30 VvAPs with the complete ASP domain and their Arabidopsis orthologs, as well as their gene and protein features were analyzed and their cellular localization was predicted. Moreover, expression profiles of VvAP genes in six different tissues were determined, and their transcript abundance under various stresses and hormone treatments were measured. Twenty-seven VvAP genes were expressed in at least one of the six tissues examined; nineteen VvAPs responded to at least one abiotic stress, 12 VvAPs responded to powdery mildew infection, and most of the VvAPs responded to SA and ABA treatments. Furthermore, integrated synteny and phylogenetic analysis identified orthologous AP genes between grape and Arabidopsis, providing a unique starting point for investigating the function of grape AP genes. Conclusions The genome-wide identification, evolutionary and expression analyses of grape AP genes provide a framework for future analysis of AP genes in defining their roles during stress response. Integrated synteny and phylogenetic analyses provide novel insight into the functions of less well-studied genes using information from their better understood orthologs.

• 2

  Pulsed resources and climate-induced variation in the reproductive traits of wild boar under high hunting pressure

  The Journal of animal ecology · 2009

  📚 52 citations🎯 RCR 1.94🔓 Open Access📄 PDF gratuit ↗

  Lire l'abstract Crossref ↓

  Summary 1. Identifying which factors influence age and size at maturity is crucial for a better understanding of the evolution of life‐history strategies. In particular, populations intensively harvested, hunted or fished by humans often respond by displaying earlier age and decreased size at first reproduction. 2. Among ungulates wild boar (Sus scrofa scrofa L.) exhibit uncommon life‐history traits, such as high fertility and early reproduction, which might increase the demographic impact of varying age at first reproduction. We analysed variation in female reproductive output from a 22‐year long study of an intensively hunted population. We assessed how the breeding probability and the onset of oestrus responded to changes of female body mass at different ages under varying conditions of climate and food availability. 3. Wild boar females had to reach a threshold body mass (27–33 kg) before breeding for the first time. This threshold mass was relatively low (33–41% of adult body mass) compared to that reported in most other ungulates (about 80%). 4. Proportions of females breeding peaked when rainfall and temperature were low in spring and high in summer. Climatic conditions might act through the nutritional condition of females. The onset of oestrus varied a lot in relation to resources available at both current and previous years. Between none and up to 90% of females were in oestrus in November depending on the year. 5. Past and current resources accounted for equivalent amount of observed variations in proportions of females breeding. Thus, wild boar rank at an intermediate position along the capital–income continuum rather than close to the capital end where similar‐sized ungulates rank. 6. Juvenile females made a major contribution to the yearly reproductive output. Comparisons among wild boar populations facing contrasted hunting pressures indicate that a high demographic contribution of juveniles is a likely consequence of a high hunting pressure rather than a species‐specific life‐history pattern characterizing wild boar.

• 3

  Complementary alternative medical therapies for heart surgery patients: feasibility, safety, and impact

  The Annals of thoracic surgery · 2006

  📚 50 citations🎯 RCR 1.96🩺 Clinique🔓 Open Access📄 PDF gratuit ↗

Publications scientifiques (44) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

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