📇 Rhumatologue · COLOMBES · (92) · Libéral
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Délais de RDV courts dans la région
136 rhumatos / 100 000 hab. — département bien doté
✨ Génération du profil synthétique IA en cours…
CABINET DU DR ANNE-SOPHIE PERRIER
145-147 SISA MSP LA COLOMBE BOULEVARD DE VALMY, 92700 COLOMBES
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Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Bio-medical materials and engineering · 2010
Due to the actual interest for bioengineering in the osteoarthritis (OA) healing context, researchers need accurate qualitative and quantitative methodologies to evaluate in vivo the integration and functionality of their cartilage-like biomaterials. As in clinical diagnostic strategies, advances in Magnetic Resonance Imaging (MRI) seem promising for non-vulnerant assessments of articular cartilage bio-architecture and morphology in small animal models. These experimental models are commonly used to monitor the physiopathology of OA and to evaluate therapeutic responses mediated by chondroprotective drugs or tissue engineering. Nowadays, the application of MR protocols to in vivo small animal cartilage imaging is achievable with the development of high magnetic fields and the adaptation of methodologies to reach the required spatial resolution and contrast. The purpose of this article is to summarize these current MRI strategies used for in vivo small animal articular cartilage assessments.
Journal of scleroderma and related disorders · 2025
Introduction: Systemic sclerosis is a systemic autoimmune disease that can affect the hands leading to a deterioration in function. Unfortunately, current medical treatments are considered insufficient to improve patients’ quality of life. However, innovative surgical and injectable treatments are available. Patients and methods: A systematic review of the literature on surgical and injectable treatments available to hand surgeons was carried out according to the PRISMA criteria. All the articles selected were analysed qualitatively and descriptively, and where possible the extracted data were summarised quantitatively. Results and discussion: Twenty-nine articles were therefore included, comprising 704 patients and 546 procedures. Nine different treatments were identified. Botulinum toxin injections have shown promising clinical results in the treatment of Raynaud’s phenomenon, digital ulcers and pain, but have not been confirmed in randomised placebo-controlled trials. Injections of adipose-derived stromal vascular fraction showed positive results in Raynaud’s phenomenon, digital ulcer, pain and function, but not in randomised placebo-controlled trials. Autologous fat grafting has shown significant results in Raynaud Phenomenon (RP) and digital ulcers (DUs) healing and prevention. Peripheral sympathectomy has shown moderate beneficial effects with frequent adverse events, and should be reserved for severe cases. Transluminal angioplasty has shown encouraging results, but studies with a high level of evidence are needed. Finally, symptomatic calcinosis cutis should be treated by resection or carbon dioxide (CO2) laser. A treatment algorithm is provided in the Supplemental Appendix. Conclusion: Interventional treatments for scleroderma of the hand have shown an overall trend of efficacy, but some of the beneficial effects have not been found in studies with a high level of evidence. Further well-conducted studies are needed.
Quantitative imaging in medicine and surgery · 2021
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Bio-medical materials and engineering · 2010 · Journal Article
Goebel JC, Pinzano A, Grenier D, Perrier AL, et al.
Revue medicale suisse · 2008 · Journal Article
Nendaz M, Perrier A
Quantitative imaging in medicine and surgery · 2021 · Journal Article
Tse Ve Koon K, Grenier D, Taborik F, Perrier AL, et al.
Journal of scleroderma and related disorders · 2025 · Journal Article
Perrier A, Pugnet G, Chaput B, Gandolfi S