Docteur ROMAIN GASTALDI

Bibliographie

• Reliability of ultrasound assessment of elementary lesions in psoriatic arthritis and development of a reference dactylitis Atlas

  2026

  ArticleRheumatology

• Gender influences adhesion to recommendations for optimal comorbidity screening and management of patients with chronic inflammatory rheumatic diseases starting a biological disease-modifying antirheumatic drug

  2024

  ArticleRMD Open

• Retropulsion with tilted postural vertical causing backward falls in an individual with Parkinson's disease: Improvement by specific rehabilitation

  2023

  ArticleAnnals of Physical and Rehabilitation Medicine

• Gout and Levodopa: An unknown adverse effect?

  2021

  ArticleFundamental & Clinical Pharmacology

• COVID-19 outcomes in patients with inflammatory rheumatic and musculoskeletal diseases treated with rituximab: a cohort study

  2021

  ArticleThe Lancet Rheumatology

• Severity of COVID-19 and survival in patients with rheumatic and inflammatory diseases: data from the French RMD COVID-19 cohort of 694 patients

  2020

  ArticleAnnals of the Rheumatic Diseases

• Implementation of comorbidities’ systematic screening program in daily practice in France

  2020

  ArticleJoint Bone Spine

• Rhumatologie interventionnelle : gestes écho-guidés

  2020

  ArticleRevue du Rhumatisme monographies

Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).

Localisation

Adresses géocodées via la Base Adresse Nationale (api-adresse.data.gouv.fr). Précision indicative.

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• HOPITAL SUD - CHU38

  Avenue DE KIMBERLEY, 38130 Échirolles

  ☎ 0476767575Hospitalier🏥 Voir cet établissement
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Prendre rendez-vous & contact

Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Top publications · les plus citées

• 1

  A proposal for a pediatric version of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index based on the analysis of 1,015 patients with juvenile-onset systemic lupus erythematosus

  Arthritis and rheumatism · 2006

  📚 108 citations🎯 RCR 3.55Top 13% NIH

  Lire l'abstract Crossref ↓

  AbstractObjectiveTo devise a modified version of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index (SDI) for use in children and adolescents with systemic lupus erythematosus (SLE), based on the frequency and distribution of damage in patients with juvenile‐onset SLE and the sources of damage that are most suitable for inclusion in a pediatric damage index.MethodsIn this cross‐sectional study, damage was assessed through the SDI. Clinical assessments included evaluation of growth failure and delayed puberty, which were believed to be important sources of damage that are not incorporated in the SDI but should be included in a pediatric version of the instrument.ResultsA total of 1,015 patients with juvenile‐onset SLE in 39 countries were enrolled in the study. Of these, 405 patients (39.9%) had an SDI score of ≥1 (mean ± SD score 0.8 ± 1.4). Renal damage (13%), neuropsychiatric damage (10.7%), and musculoskeletal damage (10.7%) were observed most frequently, followed by ocular damage (8.2%) and skin damage (7.6%). Growth failure and delayed puberty were recorded in 15.3% and 11.3% of patients, respectively. A pediatric version of the SDI was devised, with inclusion of growth failure and delayed puberty as new domains.ConclusionWe propose a modified version of the SDI for use in patients with juvenile‐onset SLE. This new instrument warrants prospective validation in other populations of patients seen in different clinical or research settings.

• 2

  Clinical patterns of Fusarium infections in immunocompromised patients

  The Journal of infection · 1994

  📚 76 citations🎯 RCR 3.59Top 13% NIH
• 3

  Phenotypic and functional characterization of switch memory B cells from patients with oligoarticular juvenile idiopathic arthritis

  Arthritis research & therapy · 2009

  📚 38 citations🔓 Open Access📄 PDF gratuit ↗

  Lire l'abstract Crossref ↓

  Abstract Introduction In chronic inflammatory disorders, B cells can contribute to tissue damage by autoantibody production and antigen presentation to T cells. Here, we have characterized synovial fluid and tissue B-cell subsets in patients with oligoarticular juvenile idiopathic arthritis (JIA), an issue not addressed before in detail. Methods B cells from synovial fluid (SF) and peripheral blood (PB) of 25 JIA patients, as well as from PB of 20 controls of comparable age, were characterized by multicolor flow cytometry. Immunoglobulin-secreting cells were detected by ELISPOT. Immunohistochemical analyses of synovial tissue from three JIA patients were performed. Results JIA SF B cells were enriched in CD27+ and CD27- switch memory B cells, but not in CD27+ IgM memory B cells, compared with patient and control PB. Plasma blasts were more abundant in SF and secreted higher amounts of IgG. Lymphoid aggregates not organized in follicle-like structures were detected in synovial tissue sections and were surrounded by CD138+ plasma cells. Finally, transitional B cells were significantly increased in JIA PB versus SF or control PB. CCR5, CCR8, CXCR2, and CXCR3 were upregulated, whereas CCR6, CCR7, and CXCR5 were downregulated on SF CD27+ and CD27- switch memory B cells compared with their circulating counterparts. SF CD27+ and CD27- switch memory B cells expressed at high levels the costimulatory molecule CD86 and the activation marker CD69. Conclusions This study demonstrates for the first time an expansion of activated switch memory B cells and of IgG-secreting plasma blasts in the SF from oligoarticular JIA patients. Memory B cells belonged to either the CD27+or the CD27- subsets and expressed CD86, suggesting their involvement in antigen presentation to T cells. Patterns of chemokines-receptor expression on CD27+ and CD27- switch memory B cells delineated potential mechanisms for their recruitment to the inflamed joints.

Publications scientifiques (21) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

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