Docteur Anne DUPONT

Thèses universitaires

• Analyse de l’entraînement et des conséquences fonctionnelles du remodelage cardio-vasculaire étudié en IRM chez le triathlète amateur longue distance

  2021

  Analysis of training and functional consequences of cardiovascular remodeling studied by MRI in amateur long-distance triathletes

  Sciences de la vie et de la santé🎓 Université de Lorraine

  Direction : Damien Mandry, Mathias Poussel

• Influence de la concentration du glutamate sur la liaison du 18F-FPEB au récepteur métabotropique du glutamate de sous-type 5 : une étude translationnelle

  2021

  Influence of glutamate concentration on 18F-FPEB binding to subtype 5 metabotropic glutamate receptor : a translational study

  Sciences de la vie et de la santé🎓 Tours

  Direction : Maria Joao Santiago-Ribeiro, Nicolas Arlicot

Source : catalogue national des thèses theses.fr (ABES). Ne couvre que les doctorats / HDR — les thèses d'exercice (DES) sont archivées dans les SCD universitaires.

Lieu de consultation

• GHU APHP NUP SITE LARIBOISIERE

  2 Rue AMBROISE PARE, 75475 Paris 10e Arrondissement

  ☎ 0149956565Hospitalier🏥 Voir cet établissement

Tarifs & secteur de conventionnement

Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).

Prendre rendez-vous & contact

Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Top publications · les plus citées

• 1

  Long-Term Outcome and Prognostic Factors of Complications in Thromboangiitis Obliterans (Buerger's Disease): A Multicenter Study of 224 Patients

  Journal of the American Heart Association · 2018

  📚 44 citations🎯 RCR 2.97Top 16% NIH🔓 Open Access📄 PDF gratuit ↗

  Lire l'abstract Crossref ↓

  Background Data regarding long‐term outcome of patients with thromboangiitis obliterans are lacking and most series come from India and Japan. In this study, we assess long‐term outcome and prognostic factors in a large cohort of thromboangiitis obliterans. Methods and Results Retrospective multicenter study of characteristics and outcomes of 224 thromboangiitis obliterans patients fulfilling Papa's criteria were analyzed. Factors associated with vascular events and amputations were identified. The median age at diagnosis was 38.5 (32–46) years, 51 (23.8%) patients were female, and 81.7% were whites. After a mean follow‐up of 5.7 years, vascular events were observed in 58.9%, amputations in 21.4%, and death in 1.4%. The 5‐, 10‐, and 15‐year vascular event‐free survival and amputation‐free survival were 41% and 85%, 23% and 74%, and 19% and 66%, respectively. Ethnic group (nonwhite) (hazard ratio 2.35 [1.30–4.27] P =0.005) and limb infection at diagnosis (hazard ratio 3.29 [1.02–10.6] P =0.045) were independent factors of vascular event‐free survival. Factor associated with amputation was limb infection (hazard ratio 12.1 [3.5–42.1], P <0.001). Patients who stopped their tobacco consumption had lower risk of amputation ( P =0.001) than those who continued. Conclusions This nationwide study shows that 34% of thromboangiitis obliterans patients will experience an amputation within 15 years from diagnosis. We identified high‐risk patients for vascular complications and amputations.

• 2

  Prognosis of large vessel involvement in large vessel vasculitis

  Journal of autoimmunity · 2020

  📚 19 citations🎯 RCR 1.38🔓 Open Access📄 PDF gratuit ↗
• 3

  Long-term control of acromegaly after pituitary surgery in South-Eastern Norway

  Acta neurochirurgica · 2023

  📚 12 citations🎯 RCR 2.69Top 19% NIH🔓 Open Access📄 PDF gratuit ↗

  Lire l'abstract Crossref ↓

  Abstract Purpose Sustained cure of acromegaly can only be achieved by surgery. Most growth hormone (GH) secreting pituitary adenomas are macroadenomas (≥ 10 mm) at diagnosis, with reported surgical cure rates of approximately 50%. Long-term data on disease control rates after surgery are limited. Our aim was to estimate short- and long-term rates of biochemical control after pituitary surgery in acromegaly and identify predictive factors. Methods Patients operated for GH-secreting pituitary adenomas between 2005–2020 were included from the local pituitary registry (n = 178). Disease activity and treatment data were recorded at one-year (short-term) and five-year (long-term) postoperative follow-up. Biochemical control was defined as insulin-like growth factor 1 (IGF-1) ≤ 1.2 × upper limit of normal value. Multivariate regression models were used to identify factors potentially predicting biochemical control. Results A total of 178 patients with acromegaly (median age at diagnosis 49 (IQR: 38–59) years, 46% women) were operated for a pituitary adenoma. Biochemical control was achieved by surgery in 53% at short-term and 41% at long-term follow-up, without additional treatment for acromegaly. Biochemical control rates by surgery were of same magnitude in paired samples (45% vs. 41%, p = 0.213) for short- and long-term follow-up, respectively. At short-term, 62% of patients with microadenomas and 51% with macroadenomas, achieved biochemical control. At long-term, the biochemical control rate was 58% for microadenomas and 37% for macroadenomas (p = 0.058). With adjunctive treatment, 82% achieved biochemical control at long-term. Baseline IGF-1 levels significantly predicted biochemical control by surgery at short-term (OR: 0.98 (95% CI: 0.96–0.99), p = 0.011), but not at long-term (OR: 0.76 (95% CI: 0.57–1.00), p = 0.053). Conclusion In unselected patients with acromegaly, the long-term biochemical control rate remains modest. Our findings indicate a need to identify patients at an earlier stage and improve therapeutic methods and surgical outcomes.

Publications scientifiques (23) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

Datasets & protocoles partagés

• Figure 3 in The tail tells the tale: taxonomy and biogeography of some Atlantic Chelidonura (Gastropoda: Cephalaspidea: Aglajidae) inferred from nuclear and mitochondrial gene data

  Image2011Zenodo

  Figure 3. Drawings of the penis and prostate of several specimens examined. A–K, Chelidonura berolina: A, specimen from Bahamas (LACM 176428); B, specimen from Bahamas (LACM 176428); C, specimen from Bahamas (LACM 176431

• 10ème Journée de la RECHERCHE HOSPITALO-UNIVERSITAIRE 2015- « Ma recherche en 300 secondes TQC »

  Audiovisual2016Canal-U/Médecine

  « Ma recherche en 300 secondes TQC »

• Figure 1 in The tail tells the tale: taxonomy and biogeography of some Atlantic Chelidonura (Gastropoda: Cephalaspidea: Aglajidae) inferred from nuclear and mitochondrial gene data

  Image2011Zenodo

  Figure 1. External morphology of some specimens of Chelidonura showing the range of colour variation. Specimens are grouped according to the authors' interpretation of species boundary hypotheses proposed in the literatu

• Figure 3 in The tail tells the tale: taxonomy and biogeography of some Atlantic Chelidonura (Gastropoda: Cephalaspidea: Aglajidae) inferred from nuclear and mitochondrial gene data

  Image2011Zenodo

  Figure 3. Drawings of the penis and prostate of several specimens examined. A–K, Chelidonura berolina: A, specimen from Bahamas (LACM 176428); B, specimen from Bahamas (LACM 176428); C, specimen from Bahamas (LACM 176431

• Figure 4 in The tail tells the tale: taxonomy and biogeography of some Atlantic Chelidonura (Gastropoda: Cephalaspidea: Aglajidae) inferred from nuclear and mitochondrial gene data

  Image2011Zenodo

  Figure 4. Scanning electron micrographs of the protoconch morphology or apical shell morphology of some specimens examined. Arrows indicate transitions in growth line pattern. A–D, Chelidonura africana: A, specimen from

• Figure 5 in The tail tells the tale: taxonomy and biogeography of some Atlantic Chelidonura (Gastropoda: Cephalaspidea: Aglajidae) inferred from nuclear and mitochondrial gene data

  Image2011Zenodo

  Figure 5. Mating sequence of two individuals of Chelidonura berolina belonging to two different colour forms. Single digit numbers indicate the sequence of events. Multiple digit numbers indicated the time at which the p

Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).

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