Docteur Marion POUDRET-FLEURY

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Adresses géocodées via la Base Adresse Nationale (api-adresse.data.gouv.fr). Précision indicative.

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• CABINET DU DR Marion POUDRET

  INFIRMERIE — 1 CHEMIN DU PENTHOD, 69300 Caluire-et-Cuire

  Libéral
  40 m43 m43 m44 m

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Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Top publications · les plus citées

• 1

  In situ measurements of dissolved gases in xylem sap as tracers in plant physiology

  Tree physiology · 2026

  📚 3 citations🔓 Open Access📄 PDF gratuit ↗

  Lire l'abstract Crossref ↓

  Abstract Trees transport gases from the ground into the atmosphere through the process of transpiration. Tracing gases transported through this mechanism continuously and under field conditions remains an experimental challenge. Here we measured gases dissolved in the tree sap in situ and in real time, aiming to simultaneously analyse the transport of several gases (He, Ar, Kr, N2, O2 and CO2) from the soil, through the trees, into the atmosphere. We constructed and inserted custom-made semi-permeable membrane probes in the xylem of a fir tree and measured gas abundances at different heights using a portable gas equilibrium membrane-inlet mass spectrometer (‘miniRUEDI’). With this method, we were able to continuously measure the abundances of He, Ar, Kr, N2, O2 and CO2 in sap over several weeks. We observed diurnal variations of CO2 and O2 concentrations that reflected tree physiological activities. As a proof of the concept that trees do uptake dissolved gases in soil water, we irrigated the tree with He-enriched water in a tracer experiment and were able to determine upward sap flow velocity. Measurements of inert gases together with reactive species, such as CO2 and O2, allowed separation of the physical transport and exchange of gases derived from the soil or atmosphere from biological reactions. We discuss the opportunities that our technique provides for continuous in situ measurements of gases in the tree sap.

• 2

  Personalization Strategies for Increasing Engagement With Digital Mental Health Resources: Sequential Multiple Assignment Randomized Trial

  JMIR mental health · 2025

  📚 2 citations🩺 Clinique🔓 Open Access

  Lire l'abstract Crossref ↓

  Abstract Background Although web-based mental health resources have the potential to assist millions, particularly those who face barriers to treatment, most mental health website visitors disengage before accessing resources that can help improve their mental health. Objective We used a sequential multiple assignment randomized trial to test whether personalized tailoring improved engagement on a self-guided mental health website. Methods Data were collected via voluntary response sampling on the Mental Health America website. Inclusion criteria included residing in the United States and viewing a postscreening survey after completing the Patient Health Questionnaire-9 (PHQ-9). Participants were randomized to 1 of 2 postscreening survey conditions: the demographics survey or the Next Steps survey, which included additional tailoring questions assessing perceived need and participants’ intended next steps. Participants who viewed the following screening results page were subsequently randomized to 1 of 5 conditions that displayed nontailored or tailored messages and featured resources, as well as persistent general resources that did not vary by condition. Data were analyzed using logistic regressions predicting disengagement and clicks on featured resources (versus persistent general resources) by condition. Results Adding questions to inform tailoring significantly increased the odds of disengaging by 14% (demographics survey: 25%; Next Steps survey: 27.5%; odds ratio [OR] 1.14, 95% CI 1.11‐1.16; P <.001). Among participants who viewed a postscreening survey (n=169,647), 87,712 participants were randomized to the demographics survey condition, and 81,935 participants were randomized to the Next Steps survey condition. Among participants who submitted the demographics survey (n=38,490), tailoring resources to demographics reduced the odds of disengaging by 10% (OR 0.90, 95% CI 0.87‐0.94; P <.001) and, among those who engaged, increased the odds of clicking a featured resource versus a persistent general resource by 90% (OR 1.90, 95% CI 1.79‐2.01; P <.001). Among participants who submitted the Next Steps survey (n=34,204), tailoring messages to perceived need ( P =.33), tailoring resources to intended next steps ( P =.51), and a combination of both ( P =.52) did not significantly reduce the odds of disengaging compared with the nontailored condition. However, tailoring resources to intended next steps and combining a tailored message to perceived need with tailored resources to intended next steps increased the odds of clicking a featured resource by 25% (OR 1.25, 95% CI 1.14‐1.37; P <.001) and 34% (OR 1.34, 95% CI 1.23‐1.47; P <.001), respectively. Tailoring resources to demographics was significantly more effective in improving engagement than tailoring to perceived need or intended next steps ( P ≤.004). Conclusions There was a small but statistically significant cost to engagement from adding tailoring questions assessing perceived need and intended next steps. Among the strategies tested in this study, tailoring resources to demographics was the most effective strategy for increasing engagement among visitors who viewed their screening results. This study demonstrates how personalization may increase engagement with mental health websites and provides design implications for future research.

• 3

  Two decades of hepatitis E in solid organ transplantation: A retrospective monocentric analysis

  Hepatology (Baltimore, Md.) · 2026

  📚 1 citations

  Lire l'abstract Crossref ↓

  Background and aims: The awareness regarding hepatitis E virus (HEV) infection in solid organ transplant (SOT) had increased within the last decades after the reports of chronicity and associated complications. The aim of this study was to describe HEV outcome over a long period in a large cohort of SOT patients. Approach & Results: This retrospective, single-center study analyzed 6452 SOT patients followed between 2001 and 2024 and systematically screened for HEV in cases of elevated liver enzymes. Since 2016, SOT patients were also screened for HEV at 3- and 12-months post-transplantation. We assessed the incidence, natural history, treatment, and extrahepatic manifestations. HEV infection was diagnosed in 228 patients (3.53%). The incidence was significantly higher in liver-transplant patients compared to others. At 3 months post-HEV documentation, 65.1% developed chronic hepatitis, while 34.9% achieved spontaneous viral clearance. Tacrolimus use was independently associated with chronicity, while mycophenolic acid use was protective. Ribavirin was the main antiviral therapy, achieving a 91.5% sustained virological response rate when treatment was extended until complete serum and stool HEV RNA clearance. A minority of patients required multiple treatment courses or failed therapy, with some developing cirrhosis or dying viremic. Three patients died from decompensate HEV-related cirrhosis. HEV-associated neurological manifestations (2.2%) and glomerular diseases (3.9%) were observed, often resolving with viral clearance. Conclusion: HEV infection is frequent in SOT recipients, with significant risks of chronicity and extrahepatic complications. Ribavirin remains the cornerstone of treatment, and individualized duration improves outcomes. Screening for HEV is mandatory in SOT patients with elevated liver enzymes.

Publications scientifiques (50) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

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