Docteur SYLVAIN MATHIEU
✨ Profil synthétique
IA · 06/05/2026Le Docteur Sylvain Mathieu est un rhumatologue hospitalier à Clermont-Ferrand, avec une activité de recherche significative dans le domaine de la rhumatologie. Ses travaux de recherche portent principalement sur les maladies rhumatismales, notamment la polyarthrite rhumatoïde, la spondylarthrite et le lupus érythémateux systémique. Avec un h-index de 32 et plus de 200 publications, il démontre une expertise reconnue dans ce domaine.
Expertises présumées
- Polyarthrite rhumatoïde
- Spondylarthrite
- Lupus érythémateux systémique
- Goutte
- Hyperuricémie
- Ostéoarthrose
- Thérapies anti-TNF
- Corticothérapie
Synthèse automatique à partir des sources publiques (HAL, OpenAlex, theses.fr, ClinicalTrials.gov, FAI²R, ANS). Pas une évaluation clinique. Le médecin peut corriger via son compte.
Diplômes
🎓 DES & spécialité ordinale
- DES Rhumatologie
- Rhumatologie (SM)
🎓 Diplômes
- DE Docteur en médecine
Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.
Activité de recherche & publications
Source : bases de données publiques (OpenAlex, PubMed).
h-index
32
h articles cités ≥ h fois chacun. Un h de 32 = 32 publications avec 32+ citations.
Citations
3 882
Publications
205
i10-index
61
Thématiques principales
- Rheumatoid Arthritis Research and Therapies ×76
- Spondyloarthritis Studies and Treatments ×38
- Systemic Lupus Erythematosus Research ×28
- Osteoarthritis Treatment and Mechanisms ×17
- Gout, Hyperuricemia, Uric Acid ×15
Affiliations FR : Centre Hospitalier Universitaire de Clermont-Ferrand
Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.
Bibliographie
Smartphone-related pain and discomfort in hand osteoarthritis, rheumatoid arthritis, and psoriatic arthritis: results from the monocentric cross-sectional PHONERIC study
2025ArticleRheumatology International
[99mTc]Tc-NTP 15 − 5, a new proteoglycan tracer for functional imaging of joint cartilage: phase I (CARSPECT)
2025ArticleEJNMMI Research
Efficacy and safety of capsaicin 8% patches: The experience of a rheumatology department
2025ArticleSAGE Open Medicine
CADOR (Capsaicin in neuropathic-like pain in digital osteoarthritis) study protocol: a multicentre randomised parallel-group trial
2025ArticleBMJ Open
Protocol publication rate and comparison between article, registry and protocol in RCTs
2025ArticleBMC Medical Research Methodology
L'arthrose et la douleur arthrosique du point de vue des patients : une revue systématique de la littérature des études qualitatives
2024CongrèsCongrès Français de Rhumatologie
La publication des protocoles d'essais contrôlés randomisés est-elle vraiment un bon moyen d'améliorer la transparence et l'intégrité de la recherche et d'éviter les conclusions inadéquates?
2024CongrèsCongrès Français de Rhumatologie
Do SMS/e-mail reminders increase influenza vaccination of rheumatoid arthritis patients under anti-TNF: a nested randomized controlled trial in the ART e-cohort
2024ArticleRheumatology
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
Lieu de consultation
HOPITAL GABRIEL MONTPIED - CHU63
58 Rue MONTALEMBERT, 63003 Clermont-Ferrand
☎ 0473750750Hospitalier
Tarifs & secteur de conventionnement
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Prendre rendez-vous & contact
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Top publications · les plus citées
- 1Osteoarthritis year in review 2024: Epidemiology and therapy
Osteoarthritis and cartilage · 2024
- 2A Meta-Analysis of the Impact of Nutritional Supplementation on Osteoarthritis Symptoms
Nutrients · 2022
Lire l'abstract Crossref ↓
Conflicting evidence exists concerning the effects of nutrient intake in osteoarthritis (OA). A systematic literature review and meta-analysis were performed using PubMed, EMBASE, and Cochrane Library up to November 2021 to assess the effects of nutrients on pain, stiffness, function, quality of life, and inflammation markers. We obtained 52 references including 50 on knee OA. Twelve studies compared 724 curcumin patients and 714 controls. Using the standardized mean difference, improvement was significant with regard to pain and function in the curcumin group compared to placebo, but not with active treatment (i.e., nonsteroidal anti-inflammatory drugs, chondroitin, or paracetamol). Three studies assessed the effects of ginger on OA symptoms in 166 patients compared to 164 placebo controls. Pain was the only clinical parameter that significantly decreased. Vitamin D supplementation caused a significant decrease in pain and function. Omega-3 and vitamin E caused no changes in OA parameters. Herbal formulations effects were significant only for stiffness compared to placebo, but not with active treatment. A significant decrease in inflammatory markers was found, especially with ginger. Thus, curcumin and ginger supplementation can have a favorable impact on knee OA symptoms. Other studies are needed to better assess the effects of omega-3 and vitamin D.
- 3Development of Orally Efficacious Allosteric Inhibitors of TNFα via Fragment-Based Drug Design
Journal of medicinal chemistry · 2021
📚 36 citations🎯 RCR 2.33Top 22% NIH🔓 Open Access
Publications scientifiques (50) — classées par pathologie
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Transversal23
▼
Transversal23
▼- French Societies of Rheumatology and of Physical and Rehabilitation Medicine recommendations for the management of people living with hand osteoarthritis
Joint bone spine · 2026 · Journal Article
Courties A, Daste C, Homs AF, Kouki I, et al.
🩺 Clinique - Grip Strength Impairment and Neuropathic-Like Pain as Predictors of Functional Decline in Hand Osteoarthritis
Open access rheumatology : research and reviews · 2025 · Journal Article
Mathieu S, Fayet F, Salembien MH, Rodere M, et al.
📚 2 cit. - Small molecule interleukin (IL) 17A/A antagonists and antibodies blocking both IL17A/A and IL17A/F demonstrate equivalent degrees of efficacy in preclinical models of skin and joint inflammation
The Journal of pharmacology and experimental therapeutics · 2025 · Journal Article
Goedken ER, Su Z, Lipovsky A, Kannan A, et al.
📚 1 cit. - Comment on: "Paraneoplastic arthritis: a series of 92 cases"
Rheumatology (Oxford, England) · 2025 · Journal Article
Fan A, Soubrier M, Quilliot J, Tournadre A, et al.
- Use of Synofast® in routine rheumatology practice: diagnostic performance and impact on management of an acute arthritis
Advances in rheumatology (London, England) · 2025 · Journal Article
Badaire F, Lambert C, Wa CC, Oyouba Y, et al.
- Smartphone-related pain and discomfort in hand osteoarthritis, rheumatoid arthritis, and psoriatic arthritis: results from the monocentric cross-sectional PHONERIC study
Rheumatology international · 2025 · Journal Article
Mathieu S, Riou C, Couderc M, Beauger M, et al.
- [(99m)Tc]Tc-NTP 15 - 5, a new proteoglycan tracer for functional imaging of joint cartilage: phase I (CARSPECT)
EJNMMI research · 2025 · Journal Article
Chanchou M, Thivat E, Mathieu S, Levesque S, et al.
📚 1 cit. - Therapeutic JAK1 Inhibition Reverses Lupus Nephritis in a Mouse Model and Demonstrates Transcriptional Changes Consistent With Human Disease
ACR open rheumatology · 2024 · Journal Article
Twomey RE, Perper SJ, Westmoreland SV, Srinivasan S, et al.
📚 2 cit. - Soy Protein Containing Diet Attenuates Murine Drug Exposure and Activity via Hepatic and Intestinal Cytochrome P450 Induction
Drug metabolism and disposition: the biological fate of chemicals · 2023 · Journal Article
Wetter JM, Ciurlionis R, Krause CJ, Liguori MJ, et al.
📚 1 cit. - Transdermal capsaicin in hand osteoarthritis: A preliminary study
Joint bone spine · 2023 · Letter
Mathieu S, Couderc M, Glace B, Malochet-Guinamand S, et al.
📚 5 cit.🎯 RCR 1.17🔬→🩺 Translationnel - Post-traumatic stress disorder prior to diagnosis is as rare in spondyloarthritis as in non-inflammatory rheumatic conditions and rheumatoid arthritis
Joint bone spine · 2023 · Observational Study
Fan A, Glace B, Pereira B, Malochet-Guinamand S, et al.
📚 1 cit.🩺 Clinique - Frequency of cannabis use in patients with rheumatoid arthritis or spondyloarthropathies: a single-centre study
Clinical and experimental rheumatology · 2023 · Letter
Ouatah H, Authier N, Tournadre A, Fan A, et al.
📚 2 cit. - Assessment of (99m)Tc-NTP 15-5 uptake on cartilage, a new proteoglycan tracer: Study protocol for a phase I trial (CARSPECT)
Frontiers in medicine · 2022 · Journal Article
Thivat E, Chanchou M, Mathieu S, Levesque S, et al.
📚 2 cit. - Cutaneous Leukocytoclastic Vasculitis Induction Following ChAdOx1 nCoV-19 Vaccine
Cureus · 2021 · Case Reports
Shahrigharahkoshan S, Gagnon LP, Mathieu S
📚 9 cit. - Response to: 'Diabetes mellitus in ankylosing spondylitis' by Liao et al
Annals of the rheumatic diseases · 2021 · Letter
Mathieu S, Soubrier M
- Disease-modifying drug retention rate according to patient age in patients with early rheumatoid arthritis: analysis of the ESPOIR cohort
Rheumatology international · 2021 · Journal Article
Mathieu S, Pereira B, Saraux A, Richez C, et al.
📚 4 cit. - Decision Tree With Only Two Musculoskeletal Sites to Diagnose Polymyalgia Rheumatica Using [(18)F]FDG PET-CT
Frontiers in medicine · 2021 · Journal Article
Flaus A, Amat J, Prevot N, Olagne L, et al.
📚 17 cit.🎯 RCR 1.71🔬→🩺 Translationnel - The Effect of TNF and Non-TNF-Targeted Biologics on Body Composition in Rheumatoid Arthritis
Journal of clinical medicine · 2021 · Journal Article
Vial G, Lambert C, Pereira B, Couderc M, et al.
📚 9 cit.🔬→🩺 Translationnel - Development of Orally Efficacious Allosteric Inhibitors of TNFα via Fragment-Based Drug Design
Journal of medicinal chemistry · 2021 · Journal Article
Dietrich JD, Longenecker KL, Wilson NS, Goess C, et al.
📚 36 cit.🎯 RCR 2.33 - NRF2 activator A-1396076 ameliorates inflammation in autoimmune disease models by inhibiting antigen dependent T cell activation
Journal of translational autoimmunity · 2021 · Journal Article
Goess C, Terrillon S, Mayo M, Bousquet P, et al.
📚 10 cit. - Answer to Grzelecki et al., Joint Bone Spine 2020, doi:10.1016/j.jbspin.2020.04.022
Joint bone spine · 2020 · Letter
Couderc M, Peyrode C, Pereira B, Miot-Noirault E, et al.
📚 1 cit. - Chronic bursitis and tenosynovitis revealing Whipple's disease
Joint bone spine · 2020 · Case Reports
Dubost JJ, Couderc M, Mathieu S, Tournadre A, et al.
📚 3 cit. - Utility of (18)F-Fluorodeoxyglucose Positron Emission Tomography in Inflammatory Rheumatism, Particularly Polymyalgia Rheumatica: A Retrospective Study of 222 PET/CT
Frontiers in medicine · 2020 · Journal Article
Amat J, Chanchou M, Olagne L, Descamps L, et al.
📚 8 cit.
Revue / méta-analyse10
▼
Revue / méta-analyse10
▼- Prevalence of neuropathic-like pain phenotype in people with hand osteoarthritis: A systematic literature review and meta-analysis
Joint bone spine · 2026 · Journal Article
Mathieu S, Fauchon C, Courties A, Sellam J
- Prevalence and impact of sleep disorders in osteoarthritis: A systematic review and meta-analysis
Osteoarthritis and cartilage open · 2026 · Journal Article
Mathieu S, Rat AC, Sellam J
📚 1 cit. - Features and management of osteoarthritis from the perspective of individuals with osteoarthritis: A systematic review of qualitative studies
Osteoarthritis and cartilage open · 2025 · Journal Article
Mathieu S, Courties A, Mathy C, Perrot S, et al.
📚 5 cit.🎯 RCR 2.48🔬→🩺 Translationnel - Frequency of irritable bowel syndrome in spondyloarthritis: a multicentric cross-sectional study and meta-analysis
RMD open · 2024 · Systematic Review
Bernard J, Barnetche T, Amory C, Despres J, et al.
📚 5 cit.🎯 RCR 1.23 - Omega 3 Fatty Acids Intake Does Not Decrease the Risk of Rheumatoid Arthritis Occurrence: A Meta-Analysis. Comment on Tański et al. The Relationship between Fatty Acids and the Development, Course and Treatment of Rheumatoid Arthritis. Nutrients 2022, 14, 1030
Nutrients · 2023 · Journal Article
Mathieu S, Pereira B, Daïen C, Tournadre A, et al.
📚 3 cit. - A Meta-Analysis of the Impact of Nutritional Supplementation on Osteoarthritis Symptoms
Nutrients · 2022 · Journal Article
Mathieu S, Soubrier M, Peirs C, Monfoulet LE, et al.
📚 41 cit.🎯 RCR 5.46🔬→🩺 Translationnel - Effect of disease-modifying anti-rheumatic drugs in osteoarthritis: A meta-analysis
Joint bone spine · 2022 · Meta-Analysis
Mathieu S, Tournadre A, Soubrier M, Sellam J
📚 17 cit.🎯 RCR 2.02 - Impact of type and dose of oral polyunsaturated fatty acid supplementation on disease activity in inflammatory rheumatic diseases: a systematic literature review and meta-analysis
Arthritis research & therapy · 2022 · Journal Article
Sigaux J, Mathieu S, Nguyen Y, Sanchez P, et al.
📚 33 cit.🎯 RCR 3.51 - Cannabis use assessment and its impact on pain in rheumatologic diseases: a systematic review and meta-analysis
Rheumatology (Oxford, England) · 2021 · Journal Article
Guillouard M, Authier N, Pereira B, Soubrier M, et al.
📚 17 cit.🎯 RCR 1.77🔬→🩺 Translationnel - Dupuytren's Disease and exposure to vibration: Systematic review and Meta-analysis
Joint bone spine · 2020 · Journal Article
Mathieu S, Naughton G, Descatha A, Soubrier M, et al.
📚 16 cit.🎯 RCR 1.91🔬→🩺 Translationnel
Revue générale8
▼
Revue générale8
▼- Prevalence of neuropathic-like pain phenotype in people with hand osteoarthritis: A systematic literature review and meta-analysis
Joint bone spine · 2026 · Journal Article
Mathieu S, Fauchon C, Courties A, Sellam J
- Prevalence and impact of sleep disorders in osteoarthritis: A systematic review and meta-analysis
Osteoarthritis and cartilage open · 2026 · Journal Article
Mathieu S, Rat AC, Sellam J
📚 1 cit. - Features and management of osteoarthritis from the perspective of individuals with osteoarthritis: A systematic review of qualitative studies
Osteoarthritis and cartilage open · 2025 · Journal Article
Mathieu S, Courties A, Mathy C, Perrot S, et al.
📚 5 cit.🎯 RCR 2.48🔬→🩺 Translationnel - The relationship between circulating and tissue biomarkers and OA-related pain: A systematic literature review
Osteoarthritis and cartilage open · 2025 · Journal Article
Mathieu S, Kuhi L, Binvignat M, Conaghan PG, et al.
📚 1 cit. - Osteoarthritis year in review 2024: Epidemiology and therapy
Osteoarthritis and cartilage · 2024 · Journal Article
Courties A, Kouki I, Soliman N, Mathieu S, et al.
📚 199 cit.🎯 RCR 56.13🔬→🩺 Translationnel - Impact of type and dose of oral polyunsaturated fatty acid supplementation on disease activity in inflammatory rheumatic diseases: a systematic literature review and meta-analysis
Arthritis research & therapy · 2022 · Journal Article
Sigaux J, Mathieu S, Nguyen Y, Sanchez P, et al.
📚 33 cit.🎯 RCR 3.51 - Cannabis use assessment and its impact on pain in rheumatologic diseases: a systematic review and meta-analysis
Rheumatology (Oxford, England) · 2021 · Journal Article
Guillouard M, Authier N, Pereira B, Soubrier M, et al.
📚 17 cit.🎯 RCR 1.77🔬→🩺 Translationnel - Dupuytren's Disease and exposure to vibration: Systematic review and Meta-analysis
Joint bone spine · 2020 · Journal Article
Mathieu S, Naughton G, Descatha A, Soubrier M, et al.
📚 16 cit.🎯 RCR 1.91🔬→🩺 Translationnel
Épidémiologie & registres5
▼
Épidémiologie & registres5
▼- Longitudinal incidence of native septic arthritis in France: a 13-year analysis of the National Health Data System Database
Rheumatology (Oxford, England) · 2026 · Journal Article
Couderc M, Gomez S, Mathieu S, Chouki C, et al.
- Prevalence of neuropathic-like pain phenotype in people with hand osteoarthritis: A systematic literature review and meta-analysis
Joint bone spine · 2026 · Journal Article
Mathieu S, Fauchon C, Courties A, Sellam J
- Prevalence and impact of sleep disorders in osteoarthritis: A systematic review and meta-analysis
Osteoarthritis and cartilage open · 2026 · Journal Article
Mathieu S, Rat AC, Sellam J
📚 1 cit. - Protocol publication rate and comparison between article, registry and protocol in RCTs
BMC medical research methodology · 2025 · Journal Article
Mathieu S, Bouillon-Minois JB, Renard Triché L, Coudeyre E, et al.
📚 2 cit. - Prevalence of Migraine and Neuropathic Pain in Rheumatic Diseases
Journal of clinical medicine · 2020 · Journal Article
Mathieu S, Couderc M, Pereira B, Dubost JJ, et al.
📚 25 cit.🎯 RCR 1.60
Anti-TNF3
▼
Anti-TNF3
▼- An anti-TNF-glucocorticoid receptor modulator antibody-drug conjugate is efficacious against immune-mediated inflammatory diseases
Science translational medicine · 2024 · Journal Article
McPherson MJ, Hobson AD, Hernandez A Jr, Marvin CC, et al.
📚 18 cit.🎯 RCR 3.39 - Anti-TNF Thioester Glucocorticoid Antibody-Drug Conjugate Fully Inhibits Inflammation with Minimal Effect on Systemic Corticosterone Levels in a Mouse Arthritis Model
Journal of medicinal chemistry · 2024 · Journal Article
Marvin CC, Hobson AD, McPherson MJ, Hayes ME, et al.
📚 3 cit. - Discovery of ABBV-3373, an Anti-TNF Glucocorticoid Receptor Modulator Immunology Antibody Drug Conjugate
Journal of medicinal chemistry · 2022 · Journal Article
Hobson AD, McPherson MJ, Hayes ME, Goess C, et al.
📚 30 cit.🎯 RCR 2.48🔬→🩺 Translationnel
Corticothérapie2
▼
Corticothérapie2
▼- Glucocorticoid trajectories over 2 years in patients with rheumatoid arthritis in a real-life setting
RMD open · 2023 · Journal Article
Delteil A, Lambert C, Pereira B, Couderc M, et al.
📚 5 cit. - Design and Development of Glucocorticoid Receptor Modulators as Immunology Antibody-Drug Conjugate Payloads
Journal of medicinal chemistry · 2022 · Journal Article
Hobson AD, McPherson MJ, Waegell W, Goess CA, et al.
📚 35 cit.🎯 RCR 3.12🔬→🩺 Translationnel
Essai clinique2
▼
Essai clinique2
▼- Transcutaneous auricular vagus nerve stimulation versus sham stimulation in patients with erosive hand osteoarthritis (ESTIVAL): a randomised, multicentre, double-blind, sham-controlled trial
The Lancet. Rheumatology · 2026 · Journal Article
Courties A, Tuffet S, Cormier G, Roux CH, et al.
🩺 Clinique - CADOR (Capsaicin in neuropathic-like pain in digital osteoarthritis) study protocol: a multicentre randomised parallel-group trial
BMJ open · 2025 · Clinical Trial Protocol
Fan A, Lambert C, Sellam J, Chapurlat R, et al.
📚 2 cit.🩺 Clinique
Risque cardio-vasculaire2
▼
Risque cardio-vasculaire2
▼- Prevalence of comorbidities and cardiovascular risk factor management in hand osteoarthritis: a cross-sectional study
Rheumatology international · 2024 · Journal Article
Mathieu S, Fayet F, Salembien MH, Rodere M, et al.
📚 4 cit.🎯 RCR 1.30 - Comparison of the cardiovascular risk profile of rheumatoid arthritis versus hand osteoarthritis patients
Rheumatology international · 2023 · Journal Article
Mathieu S, Lambert C, Fayet F, Couderc M, et al.
📚 6 cit.🎯 RCR 1.25
Biothérapies non-anti-TNF1
▼
Biothérapies non-anti-TNF1
▼- Haptoglobin blood assay to assess treatment compliance in rheumatoid arthitis patients treated with tocilizumab
Clinical and experimental rheumatology · 2024 · Letter
Montagnon PY, Beauger M, Couderc M, Tournadre A, et al.
Pharmacovigilance1
▼
Pharmacovigilance1
▼- Efficacy and safety of capsaicin 8% patches: The experience of a rheumatology department
SAGE open medicine · 2025 · Journal Article
Mathieu S, Couderc M, Beauger M, Malochet-Guinamand S, et al.
Santé mentale / fatigue1
▼
Santé mentale / fatigue1
▼- Prevalence and impact of sleep disorders in osteoarthritis: A systematic review and meta-analysis
Osteoarthritis and cartilage open · 2026 · Journal Article
Mathieu S, Rat AC, Sellam J
📚 1 cit.
Sjögren1
▼
Sjögren1
▼- Do the salivary glands of patients with systemic sclerosis show ultrasonographic modifications suggestive of Sjögren's syndrome?
Annals of the rheumatic diseases · 2020 · Letter
Couderc M, Tournadre A, Mathieu S, Pereira B, et al.
📚 14 cit.🎯 RCR 1.08
