Docteur LAURENCE LEQUEN

Thèses universitaires

• Recherche systématique de mycoplasmes dans les sites extra-articulaires au cours de la polyarthrite rhumatoi͏̈de

  1995
  Médecine🎓 Bordeaux 2

  Direction : Thierry Schaeverbeke

Source : catalogue national des thèses theses.fr (ABES). Ne couvre que les doctorats / HDR — les thèses d'exercice (DES) sont archivées dans les SCD universitaires.

Publications académiques en France

Articles déposés en accès libre sur l'archive ouverte des universités françaises (HAL) — gage d'activité de recherche en France.

• Role of stress in the development of rheumatoid arthritis: a case–control study

  2021

  ArticleRheumatology

Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).

Lieu de consultation

• CENTRE HOSPITALIER DE PAU

  4 Boulevard HAUTERIVE, 64046 Pau

  ☎ 0559924848Hospitalier🏥 Centre CH ↗🏥 Voir cet établissement

Tarifs & secteur de conventionnement

Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).

Prendre rendez-vous & contact

Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Articles de presse (2)

Source : Google News (recherche par nom complet — homonymes possibles, vérifier le contenu).

• Hôpital solidaire fait son concert - Sud Ouest

  📰 Sud Ouest · 07/01/2013

  <a href="https://news.google.com/rss/articles/CBMihAFBVV95cUxQb1ZSV1NSY09INW05Y0VCRGxaMnJyYmpaN19lRTUyRDhEc0lLNXpkZXVBWnRLZVFjSzRZREVqVUZ1bHJucklkN29oSTcwVnZLaENlRnI4WlhqSEN2dy1QeUEzRENPSDladElZQWVZUlVTZTNIUkJfV1NPc2hsOTRwN3BDaFM?oc=5" target="_blank">Hôpital solidaire fait son concert</a> <font col

• Pau : l'hôpital solidaire se lance à la rescousse des associations humanitaires - La République des Pyrénées

  📰 La République des Pyrénées · 04/01/2013

  <a href="https://news.google.com/rss/articles/CBMi3AFBVV95cUxOY18yMnZTdjlsSk1HYU1iMFNfWHh5WHd4R1pGS2pncW1BRGNyRnI4V2t1NWlaWTh5TmFMSlhNTmFZUHJnRGFpeTNCYThIVzlpNzZ2NmZLVHdib1pCVVZ4WlVZNXhnaFBFaVMyUDRnUkRpRUdqMEtiNDRJQzhfdlRoejZBZWxRS1RXZmlVekRpbUphdzFnS2RHSk1CUnFJTG5Ldllwa3pKeDB0WTJwcEI0ZnRtN0psbkdPTz

Top publications · les plus citées

• 1

  Tocilizumab in refractory adult Still's disease

  Arthritis care & research · 2011

  📚 119 citations🎯 RCR 4.06Top 11% NIH

  Lire l'abstract Crossref ↓

  AbstractObjectiveThere is an unmet need for the treatment of adult Still's disease (ASD), the pathogenesis of which may involve interleukin‐6 (IL‐6). We report the first series of patients with ASD treated with tocilizumab (TCZ), a humanized anti–IL‐6 receptor antibody.MethodsAll ASD patients treated with TCZ in France between July 2006 and July 2009 after failure to all available therapies were included in this cohort study. The main outcome measures were the European League Against Rheumatism (EULAR) improvement criteria and resolution of systemic symptoms at the 3‐ and 6‐month followup periods.ResultsFourteen patients with refractory ASD were included. At the start of TCZ treatment, despite a mean prednisone dosage of 23.3 mg/day, based on a 28‐joint count, mean tender joints were 10.5, mean swollen joints were 7.9, and the mean Disease Activity Score in 28 joints was 5.61. Recurrent systemic involvement, including fever and rash, was present in 7 patients. TCZ was administered at 5–8 mg/kg every 2 or 4 weeks (8 mg/kg/month, n = 9). Eleven patients successfully completed the 6‐month study; 1 withdrew due to necrotizing angiodermatitis, another due to chest pain at each TCZ infusion, and a third due to systemic flare. A good EULAR response was observed in 64% of patients (9 of 14) at 3 months and EULAR remission was observed in 57% (8 of 14) at 6 months. Systemic symptoms were resolved in 86% of patients (6 of 7). Moreover, corticosteroid dose was reduced by 56%. No other severe adverse effects occurred.ConclusionTCZ is a promising new treatment for ASD.

• 2

  Remitting seronegative symmetrical synovitis with pitting oedema: disease or syndrome?

  Annals of the rheumatic diseases · 1995

  📚 79 citations🎯 RCR 3.15Top 15% NIH🔓 Open Access📄 PDF gratuit ↗
• 3

  Propionibacterium acnes isolated from synovial tissue and fluid in a patient with oligoarthritis associated with acne and pustulosis

  Arthritis and rheumatism · 1998

  📚 65 citations🎯 RCR 2.45Top 21% NIH

Publications scientifiques (16) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

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