Mme Docteur AMELIE FLORENT
✨ Profil synthétique
IA · 29/04/2026Le Docteur Amélie Florent est une rhumatologue libérale à Nice, titulaire d'un DIU EA-PR/MAI. Ses recherches portent principalement sur les maladies rhumatismales, notamment la spondylarthrite et l'arthrite rhumatoïde. Elle a publié 8 articles et possède un h-index de 4.
Expertises présumées
- Spondyloarthritis
- Arthrite rhumatoïde
- Psoriasis
- Biothérapies non-anti-TNF
- Recherche sur le COVID-19
- Thérapies pour les maladies rhumatismales
- Méta-analyses en rhumatologie
Synthèse automatique à partir des sources publiques (HAL, OpenAlex, theses.fr, ClinicalTrials.gov, FAI²R, ANS). Pas une évaluation clinique. Le médecin peut corriger via son compte.
Diplômes
🎓 DES & spécialité ordinale
- DES Rhumatologie
- Rhumatologie (SM)
🏅 DU / DIU
- DIU Etudes approfondies polyarthrites-maladies
🎓 Diplômes
- DE Docteur en médecine
Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.
Activité de recherche & publications
Source : bases de données publiques (OpenAlex, PubMed).
h-index
4
h articles cités ≥ h fois chacun. Un h de 4 = 4 publications avec 4+ citations.
Citations
177
Publications
8
i10-index
3
Thématiques principales
- Spondyloarthritis Studies and Treatments ×5
- Rheumatoid Arthritis Research and Therapies ×4
- Psoriasis: Treatment and Pathogenesis ×4
- COVID-19 Clinical Research Studies ×1
- SARS-CoV-2 and COVID-19 Research ×1
Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.
Bibliographie
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
Localisation
Adresses géocodées via la Base Adresse Nationale (api-adresse.data.gouv.fr). Précision indicative.
Lieu de consultation
SELARL DOCTEUR AMELIE FLORENT
35 AVENUE GEORGES CLEMENCEAU, 06000 Nice
Libéral© OpenStreetMap
Tarifs & secteur de conventionnement
Prendre rendez-vous & contact
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Top publications · les plus citées
- 1Influenza and pneumococcal vaccine coverage in 584 patients taking biological therapy for chronic inflammatory joint: A retrospective study
Joint bone spine · 2016
📚 40 citations🎯 RCR 1.88 - 2Farnesyltransferase inhibition overcomes oncogene-addicted non-small cell lung cancer adaptive resistance to targeted therapies
Nature communications · 2024
📚 14 citations🎯 RCR 1.80🔓 Open AccessLire l'abstract Crossref ↓
AbstractDrug-tolerance has emerged as one of the major non-genetic adaptive processes driving resistance to targeted therapy (TT) in non-small cell lung cancer (NSCLC). However, the kinetics and sequence of molecular events governing this adaptive response remain poorly understood. Here, we combine real-time monitoring of the cell-cycle dynamics and single-cell RNA sequencing in a broad panel of oncogenic addiction such as EGFR-, ALK-, BRAF- and KRAS-mutant NSCLC, treated with their corresponding TT. We identify a common path of drug adaptation, which invariably involves alveolar type 1 (AT1) differentiation and Rho-associated protein kinase (ROCK)-mediated cytoskeletal remodeling. We also isolate and characterize a rare population of early escapers, which represent the earliest resistance-initiating cells that emerge in the first hours of treatment from the AT1-like population. A phenotypic drug screen identify farnesyltransferase inhibitors (FTI) such as tipifarnib as the most effective drugs in preventing relapse to TT in vitro and in vivo in several models of oncogenic addiction, which is confirmed by genetic depletion of the farnesyltransferase. These findings pave the way for the development of treatments combining TT and FTI to effectively prevent tumor relapse in oncogene-addicted NSCLC patients.
- 3Reactivation of cutaneous psoriasis during abatacept therapy for spondyloarthropathy
Joint bone spine · 2010
📚 14 citations
Publications scientifiques (4) — classées par pathologie
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Transversal2
▼
Transversal2
▼- Farnesyltransferase inhibition overcomes oncogene-addicted non-small cell lung cancer adaptive resistance to targeted therapies
Nature communications · 2024 · Journal Article
Figarol S, Delahaye C, Gence R, Doussine A, et al.
📚 14 cit.🎯 RCR 1.80🔬→🩺 Translationnel - Influenza and pneumococcal vaccine coverage in 584 patients taking biological therapy for chronic inflammatory joint: A retrospective study
Joint bone spine · 2016 · Journal Article
Brocq O, Acquacalda E, Berthier F, Albert C, et al.
📚 40 cit.🎯 RCR 1.88🔬→🩺 Translationnel
Biothérapies non-anti-TNF1
▼
Biothérapies non-anti-TNF1
▼- Reactivation of cutaneous psoriasis during abatacept therapy for spondyloarthropathy
Joint bone spine · 2010 · Case Reports
Florent A, Albert C, Giacchero D, Roux C, et al.
📚 14 cit.
Revue / méta-analyse1
▼
Revue / méta-analyse1
▼- Patients with Spondyloarthritis and obesity who fail TNF antagonist therapy: Change the subcutaneous injection site before the biologic? Comment on: "Impact of obesity on the efficacy of different biologic agents in inflammatory diseases: A systematic review and meta-analysis" by Shan et al. Joint Bone Spine, 2019, 86, 173-183
Joint bone spine · 2020 · Letter
Brocq O, Acquacalda E, Florent A, Lascar T
📚 1 cit.
Revue générale1
▼
Revue générale1
▼- Patients with Spondyloarthritis and obesity who fail TNF antagonist therapy: Change the subcutaneous injection site before the biologic? Comment on: "Impact of obesity on the efficacy of different biologic agents in inflammatory diseases: A systematic review and meta-analysis" by Shan et al. Joint Bone Spine, 2019, 86, 173-183
Joint bone spine · 2020 · Letter
Brocq O, Acquacalda E, Florent A, Lascar T
📚 1 cit.