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Rhumatologue

Docteur ADELINA CONSTANTIN

📍 Mulhouse (68)HospitalierRPPS 10002461944

Diplômes

🎓 DES & spécialité ordinale

  • Rhumatologie (SM)

🎓 Diplômes

  • Diplôme éq d'un pays de l'EEE profession Médecin

Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.

Lieu de consultation

  • CENTRE DE READAPTATION DE MULHOUSE

    57 Rue ALBERT CAMUS, 68093 Mulhouse

    ☎ 0389324646Hospitalier

Tarifs & secteur de conventionnement

Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).

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Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Top publications · les plus citées

  • 1
    A Risk Score to Detect Subclinical Rheumatoid Arthritis-Associated Interstitial Lung Disease

    Arthritis & rheumatology (Hoboken, N.J.) · 2022

    📚 83 citations🎯 RCR 9.25Top 3% NIH🔓 Open Access📄 PDF gratuit ↗
    Lire l'abstract Crossref ↓

    ObjectivePatients at high risk of rheumatoid arthritis–associated interstitial lung disease (RA‐ILD) would benefit from being identified before the onset of respiratory symptoms; this can be done by screening patients with the use of chest high‐resolution computed tomography (HRCT). Our objective was to develop and validate a risk score for patients who have subclinical RA‐ILD.MethodsOur study included a discovery population and a replication population from 2 prospective RA cohorts (ESPOIR and TRANSLATE2, respectively) without pulmonary symptoms who had received chest HRCT scans. All patients were genotyped for MUC5B rs35705950. After multiple logistic regression, a risk score based on independent risk factors for subclinical RA‐ILD was developed in the discovery population and tested for validation in the replication population.ResultsThe discovery population included 163 patients with RA, and the replication population included 89 patients with RA. The prevalence of subclinical RA‐ILD was 19.0% and 16.9%, respectively. In the discovery population, independent risk factors for subclinical RA‐ILD were presence of the MUC5B rs35705950 T allele (odds ratio [OR] 3.74 [95% confidence interval (95% CI) 1.37, 10.39]), male sex (OR 3.93 [95% CI 1.40, 11.39]), older age at RA onset (for each year, OR 1.10 [95% CI 1.04, 1.16]), and increased mean Disease Activity Score in 28 joints using the erythrocyte sedimentation rate (for each unit, OR 2.03 [95% CI 1.24, 3.42]). We developed and validated a derived risk score with receiver operating characteristic areas under the curve of 0.82 (95% CI 0.70–0.94) for the discovery population and 0.78 (95% CI 0.65–0.92) for the replication population. Excluding MUC5B rs35705950 from the model provided a lower goodness of fit (likelihood ratio test, P = 0.01).ConclusionWe developed and validated a risk score that could help identify patients at high risk of subclinical RA‐ILD. Our findings support an important contribution of MUC5B rs35705950 to subclinical RA‐ILD risk.

  • 2
    VEXAS syndrome in a patient with previous spondyloarthritis with a favourable response to intravenous immunoglobulin and anti-IL17 therapy

    Rheumatology (Oxford, England) · 2021

    📚 47 citations🎯 RCR 2.99Top 16% NIH
  • 3
    Effect of risedronate on bone loss at discontinuation of denosumab

    Bone reports · 2020

    📚 22 citations🎯 RCR 1.62🔓 Open Access

Publications scientifiques (50) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

Transversal19

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Biothérapies non-anti-TNF6

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Recommandations4

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Anti-TNF3

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Épidémiologie & registres3

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Anti-IL-172

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csDMARDs2

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Essai clinique2

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Lupus2

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Activité physique / Rééducation1

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Case report / série1

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Corticothérapie1

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Ostéoporose1

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Revue / méta-analyse1

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Revue générale1

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Rhumatisme psoriasique1

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Risque cardio-vasculaire1

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Sjögren1

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Spondyloarthrite1

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Vascularites1

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