Mme Docteur MARIE-GAELLE BRAY

Localisation des cabinets

Adresses géocodées via la Base Adresse Nationale (api-adresse.data.gouv.fr). Précision indicative.

Lieux de consultation

• CABINET DU DR MARIE-GAELLE BRAY

  6TER PLACE DU GENERAL DE GAULLE, 92330 Sceaux

  Libéral
  © OpenStreetMap

  📷 Street View ↗🗺️ Maps ↗OSM ↗

• HOPITAL CROIX SAINT SIMON

  125 Rue D AVRON, 75020 Paris 20e Arrondissement

  ☎ 0144643353Hospitalier🏥 Voir cet établissement
  15 m16 m16 m16 m

  © OpenStreetMap · Photos Wikimedia Commons (CC)

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Tarifs & secteur de conventionnement

Prendre rendez-vous & contact

Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Top publications · les plus citées

• 1

  2-Methoxyestradiol inhibits experimental autoimmune encephalomyelitis through suppression of immune cell activation

  Proceedings of the National Academy of Sciences of the United States of America · 2012

  📚 46 citations🎯 RCR 1.41🔓 Open Access📄 PDF gratuit ↗

  Lire l'abstract Crossref ↓

  The endogenous metabolite of estradiol, 2-Methoxyestradiol (2ME2), is an antimitotic and antiangiogenic cancer drug candidate that also exhibits disease-modifying activity in animal models of rheumatoid arthritis (RA). We found that 2ME2 dramatically suppresses development of mouse experimental autoimmune encephalomyelitis (EAE), a rodent model of multiple sclerosis (MS). 2ME2 inhibits in vitro lymphocyte activation, cytokine production, and proliferation in a dose-dependent fashion. 2ME2 treatment of lymphocytes specifically reduced the nuclear translocation and transcriptional activity of nuclear factor of activated T-cells (NFAT) c1, whereas NF-κB and activator protein 1 (AP-1) activation were not adversely affected. We therefore propose that 2ME2 attenuates EAE through disruption of the NFAT pathway and subsequent lymphocyte activation. By extension, our findings provide a molecular rationale for the use of 2ME2 as a tolerable oral immunomodulatory agent for the treatment of autoimmune disorders such as MS in humans.

• 2

  Frequency and tolerance of antituberculosis treatment according to national guidelines for prevention of risk of tuberculosis due to tumor necrosis factor blocker treatment

  Joint bone spine · 2010

  📚 13 citations
• 3

  Reclassifying infusion therapy space at the University of Arizona: a case study

  The health care manager · 2003

  📚 1 citations

Publications scientifiques (4) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

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