Docteur AMELIE BERNARD
✨ Profil synthétique
IA · 01/05/2026Le Docteur Amélie Bernard est une rhumatologue hospitalière à Caen, titulaire d'un DIU en pathologies osseuses. Elle a une production scientifique notable avec un h-index de 22 et 72 publications, principalement axées sur des sujets de biologie végétale et des thématiques de recherche variées. Ses travaux de recherche et ses publications PubMed suggèrent une implication dans l'étude de certaines pathologies rhumatologiques.
Expertises présumées
- Goutte
- csDMARDs
- Gériatrie
- Pédiatrie
- Pathologies osseuses
- Qualité de vie et PROMs
Synthèse automatique à partir des sources publiques (HAL, OpenAlex, theses.fr, ClinicalTrials.gov, FAI²R, ANS). Pas une évaluation clinique. Le médecin peut corriger via son compte.
Diplômes
🎓 DES & spécialité ordinale
- DES Rhumatologie
- Rhumatologie (SM)
🏅 DU / DIU
- DIU Pathologies osseuses médicales
🎓 Diplômes
- DE Docteur en médecine
Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.
🏆 DU / DIU rhumato reconnus
Thèses universitaires
Source : catalogue national des thèses theses.fr (ABES). Ne couvre que les doctorats / HDR — les thèses d'exercice (DES) sont archivées dans les SCD universitaires.
Direction de thèses
🎓 1 thèse dirigéeSource theses.fr — signal de direction d'équipe / statut PU-PH (à confirmer via le site universitaire).
Activité de recherche & publications
Source : bases de données publiques (OpenAlex, PubMed).
h-index
22
h articles cités ≥ h fois chacun. Un h de 22 = 22 publications avec 22+ citations.
Citations
12 015
Publications
72
i10-index
29
Thématiques principales
- Autophagy in Disease and Therapy ×41
- Cellular transport and secretion ×13
- Lipid metabolism and biosynthesis ×10
- Plant Surface Properties and Treatments ×9
- Epigenetics and DNA Methylation ×5
Affiliations FR : Centre National de la Recherche Scientifique · Université de Bordeaux · Laboratoire de Biogenèse Membranaire
Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.
Bibliographie
Lipid/protein interplay in membrane remodeling during plant autophagy
2025Congrès20th GERLI International Lipid Meeting
Lipid/protein interplay in membrane formation and remodeling during plant autophagy
2025CongrèsJacques Monod Conference Molecular basis for membrane remodelling and organisation
The phospholipases LCAT3 and LCAT4 are key players in the final stages of autophagy in Arabidopsis
2025CongrèsPlant Proteolysis (GRS) Gordon Research Semina "Proteolysis During Plant Development and Stress Responses"
Deciphering the singularity of autophagic membranes: key lipids in autophagy
2025Congrès2025 Gordon Research Seminar
HOPping to the vacuole: Autophagosome and late endosomes combine to control plant autophagosome degradation
2024ArticleDevelopmental Cell
LCAT3 and LCAT4: dual key players in the final stages of autophagy in Arabidopsis
2024Congrès14th International Congress of the French Society of Plant Biology
AtVPS13M1 is involved in lipid remodeling in response to phosphate starvation and is located to mitochondria in Arabidopsis thaliana
2024CongrèsInternational Conference on Plant Mitochondria Biology
Un cycle formateur au service de la cohérence pédagogique par et pour tous
2024CongrèsDiversité, Réussite[s] dans l’Enseignement Supérieur (2024)
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
Lieu de consultation
CHU CAEN
Avenue COTE DE NACRE, 14033 Caen
Tarifs & secteur de conventionnement
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Prendre rendez-vous & contact
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Top publications · les plus citées
- 3Overexpression of Arabidopsis ECERIFERUM1 promotes wax very-long-chain alkane biosynthesis and influences plant response to biotic and abiotic stresses
Plant physiology · 2011
Lire l'abstract Crossref ↓
AbstractLand plant aerial organs are covered by a hydrophobic layer called the cuticle that serves as a waterproof barrier protecting plants against desiccation, ultraviolet radiation, and pathogens. Cuticle consists of a cutin matrix as well as cuticular waxes in which very-long-chain (VLC) alkanes are the major components, representing up to 70% of the total wax content in Arabidopsis (Arabidopsis thaliana) leaves. However, despite its major involvement in cuticle formation, the alkane-forming pathway is still largely unknown. To address this deficiency, we report here the characterization of the Arabidopsis ECERIFERUM1 (CER1) gene predicted to encode an enzyme involved in alkane biosynthesis. Analysis of CER1 expression showed that CER1 is specifically expressed in the epidermis of aerial organs and coexpressed with other genes of the alkane-forming pathway. Modification of CER1 expression in transgenic plants specifically affects VLC alkane biosynthesis: waxes of TDNA insertional mutant alleles are devoid of VLC alkanes and derivatives, whereas CER1 overexpression dramatically increases the production of the odd-carbon-numbered alkanes together with a substantial accumulation of iso-branched alkanes. We also showed that CER1 expression is induced by osmotic stresses and regulated by abscisic acid. Furthermore, CER1-overexpressing plants showed reduced cuticle permeability together with reduced soil water deficit susceptibility. However, CER1 overexpression increased susceptibility to bacterial and fungal pathogens. Taken together, these results demonstrate that CER1 controls alkane biosynthesis and is highly linked to responses to biotic and abiotic stresses.
Publications scientifiques (43) — classées par pathologie
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Transversal36
▼
Transversal36
▼- Nature, functions and trafficking of membrane lipids to support autophagosome formation in plant cells
Progress in lipid research · 2026 · Journal Article
Kosuth T, Dadi-Abjayou H, Bernard A
- Orbital MRI for diagnosing giant cell arteritis in cases of anterior ischaemic optic neuropathy
RMD open · 2026 · Journal Article
Brenac G, Bernard A, Lemogne B, Greigert H, et al.
- Chaperone-mediated autophagy in fish: A key function amid a changing environment
Autophagy reports · 2024 · Journal Article
Schnebert S, Vélez EJ, Goguet M, Dias K, et al.
📚 7 cit.🎯 RCR 1.38 - HOPping to the vacuole: Autophagosome and late endosomes combine to control plant autophagosome degradation
Developmental cell · 2024 · Journal Article
Dragwidge J, Bernard A
- Biomolecular condensation orchestrates clathrin-mediated endocytosis in plants
Nature cell biology · 2024 · Journal Article
Dragwidge JM, Wang Y, Brocard L, De Meyer A, et al.
📚 31 cit.🎯 RCR 5.23 - A Rare Case of Hydralazine-Induced Diffuse Alveolar Hemorrhage
Cureus · 2023 · Case Reports
Xue A, Bernard A, Moreno V, Phillips L, et al.
📚 1 cit. - Phosphatidylinositol-4-phosphate joins the dance of plant autophagosome formation
Autophagy · 2023 · Journal Article
Gomez RE, Castets J, Lupette J, Chambaud C, et al.
📚 2 cit. - Targeting Ultrastructural Events at the Graft Interface of Arabidopsis thaliana by A Correlative Light Electron Microscopy Approach
Bio-protocol · 2023 · Journal Article
Chambaud C, Cookson SJ, Ollat N, Bernard A, et al.
📚 3 cit. - SETD2 transcriptional control of ATG14L/S isoforms regulates autophagosome-lysosome fusion
Cell death & disease · 2022 · Journal Article
González-Rodríguez P, Delorme-Axford E, Bernard A, Keane L, et al.
📚 14 cit.🎯 RCR 1.05 - Phosphatidylinositol-4-phosphate controls autophagosome formation in Arabidopsis thaliana
Nature communications · 2022 · Journal Article
Gomez RE, Chambaud C, Lupette J, Castets J, et al.
📚 33 cit.🎯 RCR 2.77 - Autophagy Inhibition by Targeting PIKfyve Potentiates Response to Immune Checkpoint Blockade in Prostate Cancer
Nature cancer · 2021 · Journal Article
Qiao Y, Choi JE, Tien JC, Simko SA, et al.
📚 86 cit.🎯 RCR 4.59🔬→🩺 Translationnel - How Lipids Contribute to Autophagosome Biogenesis, a Critical Process in Plant Responses to Stresses
Cells · 2021 · Journal Article
Gomez RE, Lupette J, Chambaud C, Castets J, et al.
📚 15 cit.🎯 RCR 1.06 - Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)(1)
Autophagy · 2021 · Guideline
Klionsky DJ, Abdel-Aziz AK, Abdelfatah S, Abdellatif M, et al.
📚 2123 cit.🎯 RCR 150.64🩺 Clinique - Intramuscular tophus
Joint bone spine · 2020 · Journal Article
Bernard A, Faury A, Oehler E
📚 1 cit. - Rheumatologic Medication Use During Pregnancy
Obstetrics and gynecology · 2020 · Journal Article
Peterson EA, Lynton J, Bernard A, Santillan MK, et al.
📚 21 cit.🎯 RCR 1.41🔬→🩺 Translationnel - Complex regional pain syndrome type I masquerading as fasciitis
Joint bone spine · 2020 · Letter
Bernard A, Morice C, Marcelli C, Sarazin F, et al.
- The Effects of Confinement on Neuropsychiatric Symptoms in Alzheimer's Disease During the COVID-19 Crisis
Journal of Alzheimer's disease : JAD · 2020 · Journal Article
Boutoleau-Bretonnière C, Pouclet-Courtemanche H, Gillet A, Bernard A, et al.
📚 105 cit.🎯 RCR 6.71🔬→🩺 Translationnel - Arabidopsis CER1-LIKE1 Functions in a Cuticular Very-Long-Chain Alkane-Forming Complex
Plant physiology · 2019 · Journal Article
Pascal S, Bernard A, Deslous P, Gronnier J, et al.
📚 91 cit.🎯 RCR 5.08 - Functions of the COPII gene paralogs SEC23A and SEC23B are interchangeable in vivo
Proceedings of the National Academy of Sciences of the United States of America · 2018 · Journal Article
Khoriaty R, Hesketh GG, Bernard A, Weyand AC, et al.
📚 64 cit.🎯 RCR 2.08 - Lipids in membrane dynamics during autophagy in plants
Journal of experimental botany · 2018 · Journal Article
Enrique Gomez R, Joubès J, Valentin N, Batoko H, et al.
📚 26 cit.🎯 RCR 1.07 - Tor-dependent post-transcriptional regulation of autophagy: Implications for cancer therapeutics
Molecular & cellular oncology · 2016 · Journal Article
Hu G, McQuiston T, Bernard A, Park YD, et al.
📚 2 cit. - Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
Autophagy · 2016 · Guideline
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, et al.
📚 4402 cit.🎯 RCR 171.45🩺 Clinique - Dramatic reduction of clindamycin serum concentration in staphylococcal osteoarticular infection patients treated with the oral clindamycin-rifampicin combination
The Journal of infection · 2015 · Journal Article
Bernard A, Kermarrec G, Parize P, Caruba T, et al.
📚 34 cit.🎯 RCR 1.78🩺 Clinique - A conserved mechanism of TOR-dependent RCK-mediated mRNA degradation regulates autophagy
Nature cell biology · 2015 · Journal Article
Hu G, McQuiston T, Bernard A, Park YD, et al.
📚 97 cit.🎯 RCR 2.89🔬→🩺 Translationnel - TOR-dependent post-transcriptional regulation of autophagy
Autophagy · 2015 · Journal Article
Hu G, McQuiston T, Bernard A, Park YD, et al.
📚 12 cit. - The Arabidopsis cer26 mutant, like the cer2 mutant, is specifically affected in the very long chain fatty acid elongation process
The Plant journal : for cell and molecular biology · 2013 · Journal Article
Pascal S, Bernard A, Sorel M, Pervent M, et al.
📚 96 cit.🎯 RCR 3.35 - Arabidopsis cuticular waxes: advances in synthesis, export and regulation
Progress in lipid research · 2013 · Journal Article
Bernard A, Joubès J
📚 304 cit.🎯 RCR 10.86 - Reconstitution of plant alkane biosynthesis in yeast demonstrates that Arabidopsis ECERIFERUM1 and ECERIFERUM3 are core components of a very-long-chain alkane synthesis complex
The Plant cell · 2012 · Journal Article
Bernard A, Domergue F, Pascal S, Jetter R, et al.
📚 324 cit.🎯 RCR 10.45 - Overexpression of Arabidopsis ECERIFERUM1 promotes wax very-long-chain alkane biosynthesis and influences plant response to biotic and abiotic stresses
Plant physiology · 2011 · Journal Article
Bourdenx B, Bernard A, Domergue F, Pascal S, et al.
📚 352 cit.🎯 RCR 11.00 - Metastatic prostate cancer mimicking polymyalgia rheumatica
Case reports in emergency medicine · 2011 · Case Reports
Randazzo CT, Bernard AW, Rund DA
📚 5 cit.🔬→🩺 Translationnel - Immune changes in post-menopausal osteoporosis: the Immunos study
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2010 · Journal Article
Breuil V, Ticchioni M, Testa J, Roux CH, et al.
📚 62 cit.🎯 RCR 1.55🔬→🩺 Translationnel - Osteoporosis and renal dysfunction in a general population exposed to cadmium in China
Environmental research · 2004 · Journal Article
Jin T, Nordberg G, Ye T, Bo M, et al.
📚 119 cit.🎯 RCR 4.20🔬→🩺 Translationnel - A golden hamster model for human acute Nipah virus infection
The American journal of pathology · 2003 · Comparative Study
Wong KT, Grosjean I, Brisson C, Blanquier B, et al.
📚 193 cit.🎯 RCR 3.86 - Joint replacement. The final solution?
Advances in experimental medicine and biology · 1999 · Journal Article
Bernard AA, Zrinzo LU
📚 3 cit.🔬→🩺 Translationnel - [Osteo-arthritis and axis deviation of the knee joint in old athletes (author's transl)]
Journal belge de rhumatologie et de medecine physique = Belgisch tijdschrift voor reumatologie en fysische geneeskunde · 1973 · Journal Article
Odekerken JC, Chantraine A, Bernard A
📚 1 cit. - [A case of severe cardiac rheumatism; beneficial effect of cortisone]
Journal des sciences medicales de Lille · 1954 · Journal Article
BERNARD A, ROUSSIER J
Goutte2
▼
Goutte2
▼- [Gout]
La Revue de medecine interne · 2020 · Journal Article
Scuiller A, Pascart T, Bernard A, Oehler E
📚 25 cit.🎯 RCR 1.75 - Diagnosis of chronic gout: evaluating the american college of rheumatology proposal, European league against rheumatism recommendations, and clinical judgment
The Journal of rheumatology · 2010 · Journal Article
Peláez-Ballestas I, Hernández Cuevas C, Burgos-Vargas R, Hernández Roque L, et al.
📚 39 cit.🎯 RCR 1.45🔬→🩺 Translationnel
csDMARDs1
▼
csDMARDs1
▼- Efficacy of triple association methotrexate, sulfasalazine and hydroxychloroquine in early treatment of rheumatoid arthritis with insufficient response to methotrexate: Meta-analysis of randomized controlled trials
Joint bone spine · 2017 · Comparative Study
Mazouyès A, Clay M, Bernard AC, Gaudin P, et al.
📚 15 cit.🔬→🩺 Translationnel
Économie santé1
▼
Économie santé1
▼- Impact of Confinement on the Burden of Caregivers of Patients with the Behavioral Variant of Frontotemporal Dementia and Alzheimer Disease during the COVID-19 Crisis in France
Dementia and geriatric cognitive disorders extra · 2020 · Journal Article
Boutoleau-Bretonnière C, Pouclet-Courtemanche H, Gillet A, Bernard A, et al.
📚 21 cit.🎯 RCR 2.01🔬→🩺 Translationnel
Gériatrie1
▼
Gériatrie1
▼- Impact of Confinement on the Burden of Caregivers of Patients with the Behavioral Variant of Frontotemporal Dementia and Alzheimer Disease during the COVID-19 Crisis in France
Dementia and geriatric cognitive disorders extra · 2020 · Journal Article
Boutoleau-Bretonnière C, Pouclet-Courtemanche H, Gillet A, Bernard A, et al.
📚 21 cit.🎯 RCR 2.01🔬→🩺 Translationnel
Pédiatrie1
▼
Pédiatrie1
▼- [Search for antilymphocytic antibodies in the serum of 67 children with juvenile chronic arthritis]
Revue du rhumatisme et des maladies osteo-articulaires · 1980 · English Abstract
Boumsell L, Prieur AM, Bernard A, Coppin H, et al.
Qualité de vie / PROMs1
▼
Qualité de vie / PROMs1
▼- Quality of life issues for fibromyalgia patients
Arthritis care and research : the official journal of the Arthritis Health Professions Association · 2000 · Journal Article
Bernard AL, Prince A, Edsall P
📚 90 cit.🎯 RCR 3.70🔬→🩺 Translationnel
Revue générale1
▼
Revue générale1
▼- Lyme-associated uveitis: Clinical spectrum and review of literature
European journal of ophthalmology · 2020 · Case Reports
Bernard A, Seve P, Abukhashabh A, Roure-Sobas C, et al.
📚 25 cit.🎯 RCR 2.49🔬→🩺 Translationnel