Docteur Lara AWAD

Thèses universitaires

• Dynamique des forêts de sapin de Cilicie au Liban et changements globaux : apports des analyses palynologiques et génétiques

  2014

  Dynamics of Cilician fir forests in Lebanon and global changes : contribution of palynological and genetic analyses

  Evolution, Ecologie, Ressources génétiques, Paléontologie🎓 Montpellier 2

  Direction : Rachid Cheddadi, Carla Khater

Source : catalogue national des thèses theses.fr (ABES). Ne couvre que les doctorats / HDR — les thèses d'exercice (DES) sont archivées dans les SCD universitaires.

Bibliographie

• Genetic structure and diversity of the endangered fir tree of Lebanon (Abies cilicica Carr.) : implications for conservation

  2014

  ArticlePLoS ONE

• Impact of past environmental changes on the genetic diversity of the remnant natural populations of Cilician fir in Lebanon

  2012

  CongrèsIPC XIII / IOPC IX 2012 : 13. International Palynological Congress and 9. International Organization of Palaeobotany Conference

Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).

Livres & ouvrages

• 📕

  Efficacité à 1 mois et 6 mois des différents types d'infiltrations dans les coxarthroses (stade I-II-III) dans une étude de soins courants au CHU d'Amiens-Picardie ET-DTICox

  20240

Source : Google Books — filtre catégories médicales/santé/sciences.

Lieu de consultation

• CHU AMIENS SUD

  1 Rond point PROFESSEUR CHRISTIAN CABROL, 80054 Amiens

  ☎ 0322088000Hospitalier🏥 Centre CHU ↗🏥 Voir cet établissement

Tarifs & secteur de conventionnement

Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).

Prendre rendez-vous & contact

Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Top publications · les plus citées

• 1

  Wearable Movement Sensors for Rehabilitation: A Focused Review of Technological and Clinical Advances

  PM & R : the journal of injury, function, and rehabilitation · 2018

  📚 153 citations🎯 RCR 11.43Top 2% NIH🔓 Open Access📄 PDF gratuit ↗

  Lire l'abstract Crossref ↓

  AbstractRecent technologic advancements have enabled the creation of portable, low‐cost, and unobtrusive sensors with tremendous potential to alter the clinical practice of rehabilitation. The application of wearable sensors to track movement has emerged as a promising paradigm to enhance the care provided to patients with neurologic or musculoskeletal conditions. These sensors enable quantification of motor behavior across disparate patient populations and emerging research shows their potential for identifying motor biomarkers, differentiating between restitution and compensation motor recovery mechanisms, remote monitoring, telerehabilitation, and robotics. Moreover, the big data recorded across these applications serve as a pathway to personalized and precision medicine. This article presents state‐of‐the‐art and next‐generation wearable movement sensors, ranging from inertial measurement units to soft sensors. An overview of clinical applications is presented across a wide spectrum of conditions that have potential to benefit from wearable sensors, including stroke, movement disorders, knee osteoarthritis, and running injuries. Complementary applications enabled by next‐generation sensors that will enable point‐of‐care monitoring of neural activity and muscle dynamics during movement also are discussed.

• 2

  Structure-based design and optimization of pyrimidine- and 1,2,4-triazolo[4,3-a]pyrimidine-based matrix metalloproteinase-10/13 inhibitors via Dimroth rearrangement towards targeted polypharmacology

  Bioorganic chemistry · 2020

  📚 23 citations🎯 RCR 1.57
• 3

  Single-Cell Analysis of ADSC Interactions with Fibroblasts and Endothelial Cells in Scleroderma Skin

  Cells · 2023

  📚 12 citations🎯 RCR 1.53🔓 Open Access📄 PDF gratuit ↗

  Lire l'abstract Crossref ↓

  Adipose-derived stem cells (ADSCs) as part of autologous fat grafting have anti-fibrotic and anti-inflammatory effects, but the exact mechanisms of action remain unknown. By simulating the interaction of ADSCs with fibroblasts and endothelial cells (EC) from scleroderma (SSc) skin in silico, we aim to unravel these mechanisms. Publicly available single-cell RNA sequencing data from the stromal vascular fraction of 3 lean patients and biopsies from the skin of 10 control and 12 patients with SSc were obtained from the GEO and analysed using R and Seurat. Differentially expressed genes were used to compare the fibroblast and EC transcriptome between controls and SSc. GO and KEGG functional enrichment was performed. Ligand–receptor interactions of ADSCs with fibroblasts and ECs were explored with LIANA. Pro-inflammatory and extracellular matrix (ECM) interacting fibroblasts were identified in SSc. Arterial, capillary, venous and lymphatic ECs showed a pro-fibrotic and pro-inflammatory transcriptome. Most interactions with both cell types were based on ECM proteins. Differential interactions identified included NTN1, VEGFD, MMP2, FGF2, and FNDC5. The ADSC secretome may disrupt vascular and perivascular inflammation hubs in scleroderma by promoting angiogenesis and especially lymphangiogenesis. Key phenomena observed after fat grafting remain unexplained, including modulation of fibroblast behaviour.

Publications scientifiques (6) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

Datasets & protocoles partagés

• Data from: Genetic structure and diversity of the endangered fir tree of Lebanon (Abies cilicica Carr.): implications for conservation

  Dataset2014Dryad

  The threatened conifer Abies cilicica currently persists in Lebanon in geographically isolated forest patches. The impact of demographic and evolutionary processes on population genetic diversity and structure were as

• Origin, location and sample size of Abies cilicica populations in Lebanon.

  Dataset2014Unpublished

• Genotype dataset for 10 microsatellite markers for 5 Abies species

  Other2014Dryad Digital Repository

  This dataset describes the genotypes detected for 10 nuclear microsatellite markers in 5 Abies species in the Mediterranean basin. Species and populations codes are those of the corresponding article.

• Observed and simulated values of the modified Garza-Williamson index for Abies cilicica populations

  Dataset2014Unpublished

Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).

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