M. Docteur Stéphane ALLOUCHE
28ans d'exercice (thèse 1998)
✨ Profil synthétique
IA · 08/05/2026Le Dr Stéphane ALLOUCHE est un rhumatologue libéral à Solliès-Pont avec une activité de recherche significative, comme en témoignent son h-index de 25 et ses 130 publications. Ses domaines de recherche couvrent notamment les mécanismes récepteurs et la signalisation, ainsi que la fonction et la pathologie mitochondriale. Il a également dirigé plusieurs thèses dans le domaine des sciences de la vie et de la santé.
Expertises présumées
- Maladies auto-immunes
- Thérapies anti-TNF
- Biomarqueurs en rhumatologie
- Épidémiologie des maladies rhumatismales
- Génétique des maladies rhumatismales
- Recherche clinique en rhumatologie
- Pathologies mitochondriales
Synthèse automatique à partir des sources publiques (HAL, OpenAlex, theses.fr, ClinicalTrials.gov, FAI²R, ANS). Pas une évaluation clinique. Le médecin peut corriger via son compte.
Diplômes
🎓 DES & spécialité ordinale
- DES Rhumatologie
- Rhumatologie (SM)
🎓 Diplômes
- DE Docteur en médecine
Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.
Thèses universitaires
Source : catalogue national des thèses theses.fr (ABES). Ne couvre que les doctorats / HDR — les thèses d'exercice (DES) sont archivées dans les SCD universitaires.
Direction de thèses
🎓 6 thèses dirigéesImplication neurοdévelοppementale de l’activateur tissulaire du plasminοgène dans les trοubles du spectre autistique
2025Doctorant·e : Cheun Pelleter
Sciences de la vie et de la santé🎓 NormandieCoeur, mitochondries, lésions d'ischémie-reperfusion : impact du diabète et du post-conditionnement par les ligands opiacés
2018Doctorant·e : Romain Richer
Aspects moleculaires et cellulaires de la biologie🎓 NormandieHyperalgésie induite par les opioïdes : intérêt du monitorage du tonus parasympathique chez l'homme et étude des mécanismes moléculaires de désensibilisation et de tolérance in vitro et chez la souris
2018Doctorant·e : Georges Daccache
Recherche clinique, innovation technologique, sante publique🎓 NormandieVariabilité glycémique : exploration in vitro des fonctions cellulaires et mitochondriales sur la lignée de cardiomyocyte HL-1
2017Doctorant·e : Patrick Mordel
Aspects moleculaires et cellulaires de la biologie🎓 NormandieConditionnement par les récepteurs couplés aux protéines G : mise au point d'un modèle in vitro
2015Doctorant·e : Marie Nowoczyn
Aspects moléculaires et cellulaires de la biologie🎓 CaenIdentification des sites potentiels de phosphorylation impliqués dans la régulation des récepteurs opioïdes delta humains induite par les arrestines
2013Doctorant·e : Elise Camacho
Aspects moléculaires et cellulaires de la biologie🎓 Caen
Source theses.fr — signal de direction d'équipe / statut PU-PH (à confirmer via le site universitaire).
Activité de recherche & publications
Source : bases de données publiques (OpenAlex, PubMed).
h-index
25
h articles cités ≥ h fois chacun. Un h de 25 = 25 publications avec 25+ citations.
Citations
2 130
Publications
130
i10-index
54
Thématiques principales
- Neuropeptides and Animal Physiology ×28
- Receptor Mechanisms and Signaling ×24
- Mitochondrial Function and Pathology ×23
- Pharmacological Receptor Mechanisms and Effects ×20
- Metabolism and Genetic Disorders ×9
Affiliations FR : Centre Hospitalier Universitaire de Caen Normandie · Université de Caen Normandie
Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.
Bibliographie
Citrate-mediated control of chromatin and mitosis
2026ArticleTrends in Endocrinology and Metabolism = Trends in Endocrinology & Metabolism
Acute leukemia in children: evaluating the necessity of routine biochemical analysis of cerebrospinal fluid
2025ArticleEuropean Journal of Pediatrics
Approches clinico-biologiques de la recherche spectrophotométrique d’oxyhémoglobine et de bilirubine dans le LCS pour la prise en charge de l’hémorragie méningée
2024ArticleAnnales de Biologie Clinique
Primary mitochondrial disorders and mimics: Insights from a large French cohort
2024ArticleAnnals of Clinical and Translational Neurology
Micropipette-guided Drug Administration (MDA) as a non-invasive chronic oral administration method in male rats
2023ArticleJournal of Neuroscience Methods
Glucose fluctuation promotes mitochondrial dysfunctions in the cardiomyocyte cell line HL-1
2023ArticlePLoS ONE
Relationship between lifestyle factors and hypertension: a cross-sectional analysis from the Gubbio study
2023ArticleActa Cardiologica
Comparison of spinal magnetic resonance imaging and classical clinical factors in predicting motor capacity in amyotrophic lateral sclerosis
2023ArticleJournal of Neurology
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
Livres & ouvrages
- 📕
Biochimie : cours & QCM
UE 1
2011 · 278 p.
avec Isabelle Denis, Pascal Gauduchon et al.
- 📕
Efficacité et tolérance de l'abatacept dans la polyarthrite rhumatoïde
expérience des services de Rhumatologie de l'AP-HM
2011 · 74 p.
Source : Google Books — filtre catégories médicales/santé/sciences.
Localisation
Adresses géocodées via la Base Adresse Nationale (api-adresse.data.gouv.fr). Précision indicative.
Lieu de consultation
CABINET DU DR StEphane ALLOUCHE
MSP LA VALLEE DU GAPEAU — 80 CHEMIN DE L'ENCLOS, 83210 Solliès-Pont
Libéral
Tarifs & secteur de conventionnement
Prendre rendez-vous & contact
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Top publications · les plus citées
- 1Opioid receptor desensitization: mechanisms and its link to tolerance
Frontiers in pharmacology · 2014
- 2Nicotinamide Deficiency in Primary Open-Angle Glaucoma
Investigative ophthalmology & visual science · 2019
📚 80 citations🎯 RCR 4.78Top 8% NIH🔓 Open Access - 3Late cardiac adverse events in patients with cancer treated with immune checkpoint inhibitors
Journal for immunotherapy of cancer · 2020
Lire l'abstract Crossref ↓
Background Immune checkpoint inhibitor (ICI)-associated early cardiac adverse events (CAEs), mostly acute and fulminant myocarditis, have been well characterized and mainly occur during the first 90 days after ICI therapy initiation. ICI-associated late CAEs (occurring after the first 90 days of treatment) have not yet been described. Methods First, we compared characteristics of a cohort involving early (defined as a CAE time to onset (TTO) of <90 days after ICI therapy initiation) and late (defined as a CAE TTO of ≥90 days after ICI therapy initiation) ICI-associated CAE consecutive cases who were referred to three French cardio-oncology units. Second, ICI-associated CAE cases were searched in VigiBase, the WHO global individual case safety report database, and early and late ICI-associated CAEs were compared. Results In the cohort study, compared with early CAE cases (n=19, median TTO of 14 days), late ICI-associated CAE cases (n=19, median TTO of 304 days) exhibited significantly more left ventricular systolic dysfunction (LVSD) and heart failure (HF) and less frequent supraventricular arrhythmias. In VigiBase, compared with early cases (n=437, 73.3%, median TTO 21 days), the late ICI-associated CAE reports (n=159, 26.7%, median TTO 178 days) had significantly more frequent HF (21.1% vs 31.4%, respectively, p=0.01). Early and late ICI-associated CAE cases had similarly high mortality rates (40.0% vs 44.4% in the cohort and 30.0% vs 27.0% in VigiBase, respectively). Conclusions Late CAEs could occur with ICI therapy and were mainly revealed to be HF with LVSD. Trial registration numbers NCT03678337, NCT03882580, and NCT03492528.
Publications scientifiques (50) — classées par pathologie
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Transversal40
▼
Transversal40
▼- Citrate-mediated control of chromatin and mitosis
Trends in endocrinology and metabolism: TEM · 2026 · Journal Article
Icard P, Plard L, Allouche S, Simula L
- Longitudinal multi-omics profiling of spinal muscular atrophy
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2026 · Journal Article
Dabaj I, Nguyen THY, Lagrue E, Ducatez F, et al.
- Mitochondrial Dysfunctions in Human Primary Coenzyme Q(10) Deficiencies
Biomolecules · 2026 · Journal Article
Fontaine F, Pénicaud R, Allouche S
- Balancing innovation and accessibility in infection imaging: lessons from the [(99m)Tc]Tc-besilesomab paradox
EJNMMI radiopharmacy and chemistry · 2026 · Journal Article
Mesnilgrante O, Ladrière T, Allouche N, Aussage L, et al.
- Accumulation of complex I assembly intermediates in a novel presentation of RTN4IP1-related disorder with developmental delay, ataxia and dyskinesia
Molecular genetics and metabolism · 2025 · Journal Article
Thys L, Beysen D, Janssens K, Jansen AC, et al.
- Bimodal solutions in peritoneal dialysis: what can we expect from different glucose volumes added to the icodextrin bag? Data from a simulation procedure
Journal of nephrology · 2025 · Journal Article
Davy A, Öberg CM, Boyer A, Lanot A, et al.
📚 1 cit. - Homozygous COQ9 mutation: a new cause of potentially treatable hereditary spastic paraplegia
European journal of human genetics : EJHG · 2025 · Journal Article
Fontaine F, Labalme A, Laurencin C, Theuriet J, et al.
📚 3 cit. - [How to promote medical biology to medical students: interest of interactive clinical cases in biological laboratory]
Annales de biologie clinique · 2025 · English Abstract
Maitre E, Fontaine F, Serrier J, Milliez PU, et al.
- [Clinical-biological approaches to the spectrophotometric detection of oxyhemoglobin and bilirubin in CSF in the management of aneurysmal subarachnoid hemorrhage]
Annales de biologie clinique · 2024 · Journal Article
Nowicki N, Allouche S, Bats ML, Bendavid C, et al.
📚 1 cit. - Primary mitochondrial disorders and mimics: Insights from a large French cohort
Annals of clinical and translational neurology · 2024 · Journal Article
Rouzier C, Pion E, Chaussenot A, Bris C, et al.
📚 4 cit.🎯 RCR 1.09 - What could cause a false increase in serum C-reactive protein concentration?
Clinical chemistry and laboratory medicine · 2024 · Letter
Bouillon M, Guénet D, Dargère S, Allouche S
📚 1 cit. - Micropipette-guided Drug Administration (MDA) as a non-invasive chronic oral administration method in male rats
Journal of neuroscience methods · 2023 · Journal Article
Heraudeau M, Roux CM, Lahogue C, Largilliere S, et al.
📚 9 cit.🎯 RCR 1.80 - Glucose fluctuation promotes mitochondrial dysfunctions in the cardiomyocyte cell line HL-1
PloS one · 2023 · Journal Article
Mordel P, Fontaine F, Dupas Q, Joubert M, et al.
📚 4 cit. - Homozygous COQ7 mutation: a new cause of potentially treatable distal hereditary motor neuropathy
Brain : a journal of neurology · 2023 · Journal Article
Jacquier A, Theuriet J, Fontaine F, Mosbach V, et al.
📚 22 cit.🎯 RCR 2.89 - Relationship between lifestyle factors and hypertension: a cross-sectional analysis from the Gubbio study
Acta cardiologica · 2023 · Journal Article
Humbert X, Licaj I, Fedrizzi S, Alexandre J, et al.
📚 8 cit.🎯 RCR 1.56 - Tracking the immune response by MRI using biodegradable and ultrasensitive microprobes
Science advances · 2022 · Journal Article
Martinez de Lizarrondo S, Jacqmarcq C, Naveau M, Navarro-Oviedo M, et al.
📚 23 cit.🎯 RCR 1.86 - Is plasma concentration of coenzyme Q10 a predictive marker for left ventricular remodelling after revascularization for ST-segment elevation myocardial infarction?
Annals of clinical biochemistry · 2021 · Journal Article
Fontaine F, Legallois D, Créveuil C, Chtourou M, et al.
📚 4 cit. - Ability of procalcitonin to distinguish between bacterial and nonbacterial infection in severe acute exacerbation of chronic obstructive pulmonary syndrome in the ICU
Annals of intensive care · 2021 · Journal Article
Daubin C, Fournel F, Thiollière F, Daviaud F, et al.
📚 12 cit.🔬→🩺 Translationnel - Impact of T161, Y318 and S363 alanine mutations on regulation of the human delta-opioid receptor (hDOPr) induced by peptidic and alkaloid agonists
Neuropharmacology · 2020 · Journal Article
Camacho E, Marie N, Dupas Q, Martel C, et al.
📚 1 cit. - Reversal of Cardiac Hypertrophy With a Ketogenic Diet in a Child With Mitochondrial Disease and Hypertrophic Cardiomyopathy
The Canadian journal of cardiology · 2020 · Case Reports
Deberles E, Maragnes P, Penniello-Valette MJ, Allouche S, et al.
📚 9 cit.🔬→🩺 Translationnel - [Measurement of angiotensin-I-converting enzyme in the blood: help for method validation]
Annales de biologie clinique · 2020 · Journal Article
Baudin B, Zendjabil M, Allouche S, Soudan B, et al.
- Serum neprilysin levels are associated with myocardial stunning after ST-elevation myocardial infarction
BMC cardiovascular disorders · 2020 · Comparative Study
Legallois D, Macquaire C, Hodzic A, Allouche S, et al.
📚 2 cit.🩺 Clinique - Plasma aldosterone and atrial mitochondrial functions of patients undergoing cardiac surgery
Future cardiology · 2020 · Journal Article
Ollitrault P, Allouche S, Chequel M, Milliez P, et al.
📚 1 cit. - Reevaluating the pathogenicity of the variations c.439 G>A and c.2132 C>T in the PLA2G6 gene
Journal of genetics · 2020 · Case Reports
Allouche S
- Late cardiac adverse events in patients with cancer treated with immune checkpoint inhibitors
Journal for immunotherapy of cancer · 2020 · Journal Article
Dolladille C, Ederhy S, Allouche S, Dupas Q, et al.
📚 69 cit.🎯 RCR 2.97🩺 Clinique - Identification of a novel splice site mutation in the SERAC1 gene responsible for the MEGDHEL syndrome
Molecular genetics & genomic medicine · 2019 · Case Reports
Snanoudj S, Mordel P, Dupas Q, Schanen C, et al.
📚 9 cit. - Spironolactone and perioperative atrial fibrillation occurrence in cardiac surgery patients: Rationale and design of the ALDOCURE trial
American heart journal · 2019 · Clinical Trial Protocol
Alexandre J, Ollitrault P, Fischer MO, Fellahi JL, et al.
📚 12 cit.🩺 Clinique - Nicotinamide Deficiency in Primary Open-Angle Glaucoma
Investigative ophthalmology & visual science · 2019 · Journal Article
Kouassi Nzoughet J, Chao de la Barca JM, Guehlouz K, Leruez S, et al.
📚 80 cit.🎯 RCR 4.78🔬→🩺 Translationnel - [Which are the significance of low level of glycated hemoglobin A1c?]
Annales de biologie clinique · 2018 · Journal Article
Bulke C, Gondolf C, Grandhomme F, Allouche S
📚 2 cit.🔬→🩺 Translationnel - PAR1 contribution in acute electrophysiological properties of oral anticoagulants in rabbit pulmonary vein sleeve preparations
Fundamental & clinical pharmacology · 2018 · Journal Article
Font J, Simeon M, Simard C, Allouche S, et al.
📚 5 cit. - Argon Exposure Induces Postconditioning in Myocardial Ischemia-Reperfusion
Journal of cardiovascular pharmacology and therapeutics · 2017 · Journal Article
Lemoine S, Blanchart K, Souplis M, Lemaitre A, et al.
📚 25 cit.🎯 RCR 1.25 - Aldoscore to predict postoperative atrial fibrillation after cardiac surgery: external validation in a Japanese cohort
Journal of hypertension · 2017 · Journal Article
Alexandre J, Sezai A, Allouche S, Fischer MO, et al.
📚 4 cit.🔬→🩺 Translationnel - Immunoanalytical characteristics of unconjugated estriol: indications and analytical performances
Annales de biologie clinique · 2016 · Journal Article
Lefevre C, Gruchy N, Guénet D, Renom G, et al.
📚 1 cit. - Is it worth to report the presence of a single and additional band in the cerebrospinal fluid detected by isoelectrofocusing?
Annales de biologie clinique · 2016 · Journal Article
Lefèvre C, Derache N, Grandhomme F, Fradin S, et al.
📚 2 cit. - Mitochondrial involvement in propofol-induced cardioprotection: An in vitro study in human myocardium
Experimental biology and medicine (Maywood, N.J.) · 2016 · Journal Article
Lemoine S, Zhu L, Gress S, Gérard JL, et al.
📚 8 cit. - Aldosterone and testosterone: two steroid hormones structurally related but with opposite electrophysiological properties during myocardial ischemia-reperfusion
Fundamental & clinical pharmacology · 2015 · Journal Article
Alexandre J, Milliez P, Rouet R, Manrique A, et al.
📚 13 cit.🔬→🩺 Translationnel - Striatal dopamine D1 and D2 receptors are differentially regulated following buprenorphine or methadone treatment
Psychopharmacology · 2015 · Journal Article
Allouche S, Le Marec T, Coquerel A, Noble F, et al.
📚 8 cit.🔬→🩺 Translationnel - Opioid receptor desensitization: mechanisms and its link to tolerance
Frontiers in pharmacology · 2014 · Journal Article
Allouche S, Noble F, Marie N
📚 116 cit.🎯 RCR 4.50🔬→🩺 Translationnel - Phenotypic diversity associated with the MT-TV gene m.1644G>A mutation, a matter of quantity
Mitochondrion · 2014 · Case Reports
Fraidakis MJ, Jardel C, Allouche S, Nelson I, et al.
📚 9 cit. - Different patterns of administration modulate propensity of methadone and buprenorphine to promote locomotor sensitization in mice
Progress in neuro-psychopharmacology & biological psychiatry · 2013 · Journal Article
Allouche S, Le Marec T, Noble F, Marie N
📚 18 cit.
Génétique2
▼
Génétique2
▼- Improved detection of mitochondrial DNA instability in mitochondrial genome maintenance disorders
Genetics in medicine : official journal of the American College of Medical Genetics · 2021 · Journal Article
Bris C, Goudenège D, Desquiret-Dumas V, Gueguen N, et al.
📚 7 cit. - No evidence for genetic association between glutamate transporter EAAT2 and Devic's neuromyelitis optica in caucasians and afro-caribbeans
Multiple sclerosis and related disorders · 2014 · Journal Article
Hanoux V, Coulbault L, Derache N, Cabre P, et al.
Revue générale2
▼
Revue générale2
▼- Severe bone pain with teriflunomide: Five case reports and review of the French pharmacovigilance database
Therapie · 2020 · Case Reports
Peyro-Saint-Paul L, Derache N, Ficheux M, Allouche S, et al.
📚 3 cit.🔬→🩺 Translationnel - Preoperative Plasma Aldosterone Levels and Postoperative Atrial Fibrillation Occurrence Following Cardiac Surgery: A Review of Literature and Design of the ALDO-POAF Study (ALDOsterone for Prediction of Post-Operative Atrial Fibrillation)
Current clinical pharmacology · 2016 · Journal Article
Chequel M, Ollitrault P, Saloux E, Parienti JJ, et al.
📚 14 cit.🔬→🩺 Translationnel
Anti-TNF1
▼
Anti-TNF1
▼- [Hypercalcemia under etanercept treatment: What to consider?]
Therapie · 2018 · Case Reports
Gondolf C, Baudart P, Fedrizzi S, Marcelli C, et al.
Biomarqueurs / Auto-Ac1
▼
Biomarqueurs / Auto-Ac1
▼- Ferritin as a predictive biomarker of severity in Covid-19
Annales de biologie clinique · 2022 · Journal Article
Perottet J, Gondolf C, Grandhomme F, Creveuil C, et al.
📚 3 cit.
Case report / série1
▼
Case report / série1
▼- Late-Onset Multiple Acyl-CoA Dehydrogenase Deficiency (MADD): A Case Report With a Complex Biochemical Profile
JIMD reports · 2025 · Journal Article
Penicaud R, Ferron JB, Valette X, Bauduin P, et al.
📚 1 cit.
Épidémiologie & registres1
▼
Épidémiologie & registres1
▼- Preoperative plasma aldosterone and the risk of atrial fibrillation after coronary artery bypass surgery: a prospective cohort study
Journal of hypertension · 2016 · Journal Article
Alexandre J, Saloux E, Chequel M, Allouche S, et al.
📚 29 cit.🎯 RCR 1.27🔬→🩺 Translationnel
IRM ostéo-articulaire1
▼
IRM ostéo-articulaire1
▼- Hyperglycemia-Induced Hypovolemia Is Involved in Early Cardiac Magnetic Resonance Alterations in Streptozotocin-Induced Diabetic Mice: A Comparison with Furosemide-Induced Hypovolemia
PloS one · 2016 · Journal Article
Joubert M, Bellevre D, Legallois D, Elie N, et al.
📚 3 cit.
Pédiatrie1
▼
Pédiatrie1
▼- Acute leukemia in children: evaluating the necessity of routine biochemical analysis of cerebrospinal fluid
European journal of pediatrics · 2025 · Journal Article
Miconi C, Maître E, Allouche S, Brunel V, et al.
Datasets & protocoles partagés
New evidence of a mitochondrial genetic background paradox: Impact of the J haplogroup on the A3243G mutation-0
Image2011figshareImpacts on the OXPHOS level, their implications on an individual level, and their impact on the distribution of populations studied within the phylogeny.<b>Copyright information:</b>Taken from "New evidence of a mitochon
New evidence of a mitochondrial genetic background paradox: Impact of the J haplogroup on the A3243G mutation-0
Image2011figshareImpacts on the OXPHOS level, their implications on an individual level, and their impact on the distribution of populations studied within the phylogeny.<b>Copyright information:</b>Taken from "New evidence of a mitochon
Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).
