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Rhumatologue

Docteur ANNE-JOELLE WEBER

📍 Évreux (27)HospitalierRPPS 10001463503

3 publis sur 5 ans

📊 Reconnaissance scientifique : 2/100📝 5 articles publiés📚 HAL (2)📕 1 livre

✨ Profil synthétique

IA · 29/04/2026

Le Docteur Anne-Joelle Weber est un rhumatologue hospitalier à Évreux, avec des intérêts de recherche dans le domaine de la rhumatologie, notamment les biosimilaires et les thérapies contre l'arthrite rhumatoïde. Ses publications sur PubMed couvrent des sujets tels que les traitements anti-TNF, la qualité de vie et les méta-analyses. Avec un h-index de 2 et 5 publications, elle contribue à la littérature scientifique dans son domaine.

Expertises présumées

  • Arthrite rhumatoïde
  • Thérapies anti-TNF
  • Biosimilaires
  • Évaluation de la qualité de vie
  • Méta-analyses en rhumatologie
  • Traitements anti-IL-23

Synthèse automatique à partir des sources publiques (HAL, OpenAlex, theses.fr, ClinicalTrials.gov, FAI²R, ANS). Pas une évaluation clinique. Le médecin peut corriger via son compte.

Diplômes

🎓 DES & spécialité ordinale

  • DES Rhumatologie
  • Rhumatologie (SM)

🎓 Diplômes

  • DE Docteur en médecine

Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.

Activité de recherche & publications

Source : bases de données publiques (OpenAlex, PubMed).

h-index

2

h articles cités ≥ h fois chacun. Un h de 2 = 2 publications avec 2+ citations.

Citations

80

Publications

5

i10-index

1

Thématiques principales

  • Biosimilars and Bioanalytical Methods ×3
  • Rheumatoid Arthritis Research and Therapies ×2
  • Angiogenesis and VEGF in Cancer ×1
  • Platelet Disorders and Treatments ×1
  • Health Systems, Economic Evaluations, Quality of Life ×1

Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.

Bibliographie

Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).

Livres & ouvrages

Source : Google Books — filtre catégories médicales/santé/sciences.

Lieu de consultation

Tarifs & secteur de conventionnement

Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).

Prendre rendez-vous & contact

Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Top publications · les plus citées

  • 1
    Association between osteoarthritis and increased risk of dementia: A systemic review and meta-analysis

    Medicine · 2019

    📚 75 citations🎯 RCR 4.09Top 10% NIH🔓 Open Access
    Lire l'abstract Crossref ↓

    Abstract Objective: To investigate the possible association between osteoarthritis (OA) and the risk of dementia. Methods: Cohort, case-control, and cross-sectional studies were obtained from wide literature search up to 20 April 2018 from following electronic databases: PubMed, Embase, Cochrane, using the MeSH terms: “osteoarthritis” AND “dementia”. The literature search was then expanded to congress abstracts. After screening and selection of relevant studies by two investigators, data was extracted. Estimates were then calculated using a random-effect size model. Sensitivity-analysis was conducted for gender and age adjusted studies and pooled for studies with STROBE quality assessment score ≥75%. Publication bias was assessed by Funnel plot. Analyses were performed using Data Analysis and Statistical Software Version 14.2. Results: Nearly 1549 publication references were initially retrieved. Twenty-six publications were checked with full-text. Six observational studies with 388,252 individuals were included. OA was associated with a significantly increased risk for dementia (OR = 1.20; 95% confidence interval (CI), 1.03–1.39, I 2 = 95.6%, P < .05). After pooling the studies with adjustment of age and gender, the risk increased (OR 1.36; 95% CI, 1.22–1.51, I 2 = 75.6%, P < .0001). After pooling the study with a STROBE Quality score ≥75% the risk for dementia was slightly increased (OR 1.33; 95% CI, 1.17–1.5, I 2 = 93.5%, p < 0.0001). Conclusions: There is an association between osteoarthritis and the risk of dementia. This meta-analysis does not provide causality. Further prospective cohort studies are needed to clarify, if knee-, hip-, or hand-OA are independent risk factors for Alzheimer's disease and vascular dementia.

  • 3
    Recent insights into the regulatory networks of NLRP3 inflammasome activation

    Journal of cell science · 2020

    📚 68 citations🎯 RCR 3.45Top 13% NIH🔓 Open Access📄 PDF gratuit ↗
    Lire l'abstract Crossref ↓

    ABSTRACT The NACHT, LRR and PYD domains-containing protein 3 (NLRP3) inflammasome is a fascinating cellular machinery endowed with the capacity for rapid proteolytic processing of the pro-inflammatory cytokine IL-1β and the cell death effector gasdermin D (GSDMD). Although its activity is essential to fight infection and support tissue homeostasis, the inflammasome complex, which consists of the danger sensor NLRP3, the adaptor apoptosis-associated speck-like protein containing a CARD (ASC; also known as PYCARD), caspase-1 and probably other regulatory proteins, also bears considerable potential for detrimental inflammation, as observed in human conditions such as gout, heart attack, stroke and Alzheimer's disease. Thus, multi-layered regulatory networks are required to ensure the fine balance between rapid responsiveness versus erroneous activation (sufficient and temporally restricted versus excessive and chronic activity) of the inflammasome. These involve multiple activation, secretion and cell death pathways, as well as modulation of the subcellular localization of NLRP3, and its structure and activity, owing to post-translational modification by other cellular proteins. Here, we discuss the exciting progress that has recently been made in deciphering the regulation of the NLRP3 inflammasome. Additionally, we highlight open questions and describe areas of research that warrant further exploration to obtain a more comprehensive molecular and cellular understanding of the NLRP3 inflammasome.

Publications scientifiques (50) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

Transversal33

Anti-TNF3

Qualité de vie / PROMs3

Revue / méta-analyse3

Revue générale3

Épidémiologie & registres2

Anti-IL-231

Biothérapies non-anti-TNF1

csDMARDs1

Économie santé1

Essai clinique1

Génétique1

Lupus1

Santé mentale / fatigue1

Tendinopathies & SCC1

Vraie vie / RWE1

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