Rhumatologue

Professeur JACQUES SANY

RPPS 10003888616

📊 Reconnaissance scientifique : 3/100📝 5 articles publiés📚 HAL (3)🎓 6 thèses dirigées

Diplômes

🎓 DES & spécialité ordinale

Rhumatologie (SM)

📚 CES (Certificat d'Études Spéciales)

CES Rhumatologie

🎓 Diplômes

DE Docteur en médecine

Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.

Direction de thèses

🎓 6 thèses dirigées

Traitement de la polyarthrite rhumatoi͏̈de par des anticorps monoclonaux anti-CD4
1999
Doctorant·e : Roser Areny Micas
Médecine🎓 Montpellier 1
Approche socio-économique de la polyarthite rhumatoi͏̈de en milieu hospitalier
1997
Doctorant·e : Milka Maravic
Médecine🎓 Montpellier 1
Implication du systéme lymphoi͏̈de associé aux muqueuses dans l'immuno-pathologie de la polyarthrite rhumatoi͏̈de
1996
Doctorant·e : Christian Jorgensen
Médecine🎓 Montpellier 1
Typage génétique HLA de classe II et facteurs pronostiques de la polyarthrite rhumatoi͏̈de
1996
Doctorant·e : Jean-Pierre Hellier
Médecine🎓 Montpellier 1
Rhumatismes et cryoglobulinémies
1996
Doctorant·e : Benoît Guerin
Médecine🎓 Montpellier 1
Efficacité et tolérance du méthotrexate au cours de la polyarthrite rhumatoi͏̈de : à propos de quatre cent soixante-euf cas personnels
1995
Doctorant·e : Philippe Viu
Médecine🎓 Montpellier 1

Source theses.fr — signal de direction d'équipe / statut PU-PH (à confirmer via le site universitaire).

Activité de recherche & publications

Source : bases de données publiques (OpenAlex, PubMed).

h-index

h articles cités ≥ h fois chacun. Un h de 3 = 3 publications avec 3+ citations.

Citations

Publications

i10-index

Thématiques principales

T-cell and B-cell Immunology ×3
Systemic Lupus Erythematosus Research ×2
Monoclonal and Polyclonal Antibodies Research ×2
Immune Cell Function and Interaction ×2
Lymphoma Diagnosis and Treatment ×1

Voir sur OpenAlex ↗

Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.

Bibliographie

Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).

Lieu de consultation

Tarifs & secteur de conventionnement

Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).

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Prendre rendez-vous & contact

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Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Top publications · les plus citées

1
Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: double-blind randomised controlled trial
Lancet (London, England) · 2004
📚 1413 citations🎯 RCR 35.64Top 0% NIH🩺 Clinique
2
Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals
Blood · 2003
📚 883 citations🎯 RCR 18.93Top 1% NIH
Lire l'abstract Crossref ↓
AbstractMesenchymal stem cells (MSCs) are largely studied for their potential clinical use. Recently, they have gained further interest after demonstration of an immunosuppressive role. In this study, we investigated whether in vivo injection of MSCs could display side effects related to systemic immunosuppression favoring tumor growth. We first showed in vitro that the murine C3H10T1/2 (C3) MSC line and primary MSCs exhibit immunosuppressive properties in mixed lymphocyte reaction. We demonstrated that this effect is mediated by soluble factors, secreted only on “activation” of MSCs in the presence of splenocytes. Moreover, the immunosuppression is mediated by CD8+ regulatory cells responsible for the inhibition of allogeneic lymphocyte proliferation. We then demonstrated that the C3 MSCs expressing the human bone morphogenetic protein 2 (hBMP-2) differentiation factor were not rejected when implanted in various allogeneic immunocompetent mice and were still able to differentiate into bone. Importantly, using a murine melanoma tumor model, we showed that the subcutaneous injection of B16 melanoma cells led to tumor growth in allogeneic recipients only when MSCs were coinjected. Although the potential side effects of immunosuppression induced by MSCs have to be considered in further clinical studies, the usefulness of MSCs for various therapeutic applications still remains of great interest. (Blood. 2003;102:3837-3844)
3
Efficacy and safety of adalimumab as monotherapy in patients with rheumatoid arthritis for whom previous disease modifying antirheumatic drug treatment has failed
Annals of the rheumatic diseases · 2004
📚 487 citations🎯 RCR 12.50Top 2% NIH🩺 Clinique🔓 Open Access📄 PDF gratuit ↗

Publications scientifiques (50) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

Transversal30

▼

[Monoclonal antibodies in the treatment of rheumatoid arthritis: toward a therapeutic revolution]
Comptes rendus biologies · 2006 · English Abstract
Sany J
📚 3 cit.
Influence of sex on disease severity in patients with rheumatoid arthritis
The Journal of rheumatology · 2005 · Journal Article
Gossec L, Baro-Riba J, Bozonnat MC, Daurès JP, et al.
📚 22 cit.
Reversal of the immunosuppressive properties of mesenchymal stem cells by tumor necrosis factor alpha in collagen-induced arthritis
Arthritis and rheumatism · 2005 · Journal Article
Djouad F, Fritz V, Apparailly F, Louis-Plence P, et al.
📚 281 cit.🎯 RCR 6.51🔬→🩺 Translationnel
Structural evaluation in the management of patients with rheumatoid arthritis: development of recommendations for clinical practice based on published evidence and expert opinion
Joint bone spine · 2005 · Journal Article
Gossec L, Fautrel B, Pham T, Combe B, et al.
📚 20 cit.🔬→🩺 Translationnel
Physical examination and laboratory tests in the management of patients with rheumatoid arthritis: development of recommendations for clinical practice based on published evidence and expert opinion
Joint bone spine · 2005 · Journal Article
Pham T, Gossec L, Fautrel B, Combe B, et al.
📚 29 cit.🔬→🩺 Translationnel
Role and modalities of information and education in the management of patients with rheumatoid arthritis: development of recommendations for clinical practice based on published evidence and expert opinion
Joint bone spine · 2005 · Journal Article
Fautrel B, Pham T, Gossec L, Combe B, et al.
📚 26 cit.🔬→🩺 Translationnel
Transcriptional profiles discriminate bone marrow-derived and synovium-derived mesenchymal stem cells
Arthritis research & therapy · 2005 · Comparative Study
Djouad F, Bony C, Häupl T, Uzé G, et al.
📚 160 cit.🎯 RCR 4.08🔬→🩺 Translationnel
HLA-DMA*0103 and HLA-DMB*0104 alleles as novel prognostic factors in rheumatoid arthritis
Annals of the rheumatic diseases · 2004 · Journal Article
Morel J, Roch-Bras F, Molinari N, Sany J, et al.
📚 22 cit.
Characteristics of patients with rheumatoid arthritis in France: a study of 1109 patients managed by hospital based rheumatologists
Annals of the rheumatic diseases · 2004 · Journal Article
Sany J, Bourgeois P, Saraux A, Durieux S, et al.
📚 25 cit.🔬→🩺 Translationnel
Costs of rheumatoid arthritis in France: a multicenter study of 1109 patients managed by hospital-based rheumatologists
The Journal of rheumatology · 2004 · Journal Article
Guillemin F, Durieux S, Daurès JP, Lafuma A, et al.
📚 46 cit.🎯 RCR 1.70🔬→🩺 Translationnel
Prognostic factors for remission in early rheumatoid arthritis: a multiparameter prospective study
Annals of the rheumatic diseases · 2004 · Journal Article
Gossec L, Dougados M, Goupille P, Cantagrel A, et al.
📚 99 cit.🎯 RCR 2.62🔬→🩺 Translationnel
Agreement between rheumatologist visit and lay interviewer telephone survey for screening for rheumatoid arthritis and spondyloarthropathy
Joint bone spine · 2004 · Comparative Study
Saraux A, Guillemin F, Fardellone P, Guggenbuhl P, et al.
📚 15 cit.🔬→🩺 Translationnel
Short-term BMP-2 expression is sufficient for in vivo osteochondral differentiation of mesenchymal stem cells
Stem cells (Dayton, Ohio) · 2004 · Journal Article
Noël D, Gazit D, Bouquet C, Apparailly F, et al.
📚 184 cit.🎯 RCR 4.62
Immunosuppressive effect of mesenchymal stem cells favors tumor growth in allogeneic animals
Blood · 2003 · Journal Article
Djouad F, Plence P, Bony C, Tropel P, et al.
📚 883 cit.🎯 RCR 18.93🔬→🩺 Translationnel
Predictive factors of 5-year health assessment questionnaire disability in early rheumatoid arthritis
The Journal of rheumatology · 2003 · Journal Article
Combe B, Cantagrel A, Goupille P, Bozonnat MC, et al.
📚 83 cit.🎯 RCR 2.54🔬→🩺 Translationnel
[Treatment of rheumatoid polyarthritis. The revolution of biotherapies]
La Revue du praticien · 2003 · Journal Article
Sany J
📚 1 cit.
[Current conception of rheumatoid polyarthritis treatment: towards a therapeutic revolution?]
Bulletin de l'Academie nationale de medecine · 2003 · Journal Article
Sany J
📚 1 cit.
Medicoeconomic evaluations in rheumatology--the example of rheumatoid arthritis
Joint bone spine · 2002 · Editorial
Maravic M, Daurès JP, Sany J
Tetracycline-inducible interleukin-10 gene transfer mediated by an adeno-associated virus: application to experimental arthritis
Human gene therapy · 2002 · Journal Article
Apparailly F, Millet V, Noël D, Jacquet C, et al.
📚 63 cit.🎯 RCR 1.34
Treatment of chronic knee synovitis with arthroscopic synovectomy: longterm results
The Journal of rheumatology · 2002 · Comparative Study
Roch-Bras F, Daurès JP, Legouffe MC, Sany J, et al.
📚 33 cit.🎯 RCR 1.32🔬→🩺 Translationnel
[TNFalpha inhibitors for the treatment of rheumatoid arthritis]
Annales de medecine interne · 2002 · English Abstract
Sany J, Kaiser MJ
Adenovirus-mediated gene transfer of urokinase plasminogen inhibitor inhibits angiogenesis in experimental arthritis
Gene therapy · 2002 · Journal Article
Apparailly F, Bouquet C, Millet V, Noel D, et al.
📚 23 cit.🔬→🩺 Translationnel
Prognostic factors for radiographic damage in early rheumatoid arthritis: a multiparameter prospective study
Arthritis and rheumatism · 2001 · Journal Article
Combe B, Dougados M, Goupille P, Cantagrel A, et al.
📚 204 cit.🎯 RCR 5.87🔬→🩺 Translationnel
Paradoxical effects of tissue inhibitor of metalloproteinases 1 gene transfer in collagen-induced arthritis
Arthritis and rheumatism · 2001 · Journal Article
Apparailly F, Noël D, Millet V, Baker AH, et al.
📚 42 cit.🔬→🩺 Translationnel
HLA-DRB1 genes and patients with late onset rheumatoid arthritis
Annals of the rheumatic diseases · 2001 · Journal Article
Hellier JP, Eliaou JF, Daurès JP, Sany J, et al.
📚 24 cit.🔬→🩺 Translationnel
Stem cells for repair of cartilage and bone: the next challenge in osteoarthritis and rheumatoid arthritis
Annals of the rheumatic diseases · 2001 · Journal Article
Jorgensen C, Noel D, Apparailly F, Sany J
📚 51 cit.🎯 RCR 1.23
Outcomes in patients with incipient undifferentiated arthritis
Joint bone spine · 2000 · Journal Article
Morel J, Legouffe MC, Bozonat MC, Sany J, et al.
📚 22 cit.🔬→🩺 Translationnel
Intracytoplasmic Th1 and Th2 cytokines in rheumatoid arthritis blood and synovial tissue
Journal of autoimmunity · 1999 · Journal Article
Bourg V, Portalès P, Fiorito S, Combe B, et al.
📚 7 cit.
Novel biologic approaches to the treatment of rheumatoid arthritis
Revue du rhumatisme (English ed.) · 1999 · Journal Article
Sany J
Anti-heat shock protein 70 kDa and 90 kDa antibodies in serum of patients with rheumatoid arthritis
Annals of the rheumatic diseases · 1999 · Journal Article
Hayem G, De Bandt M, Palazzo E, Roux S, et al.
📚 74 cit.🎯 RCR 1.84

Anti-TNF14

▼

Medico-economic evaluation of infliximab in rheumatoid arthritis--prospective French study of a cohort of 635 patients monitored for two years
Rheumatology (Oxford, England) · 2009 · Journal Article
Sany J, Cohen JD, Combescure C, Bozonnat MC, et al.
📚 3 cit.
Long-term effects of infliximab on bone and cartilage turnover markers in patients with rheumatoid arthritis
Annals of the rheumatic diseases · 2008 · Clinical Trial
Chopin F, Garnero P, le Henanff A, Debiais F, et al.
📚 98 cit.🎯 RCR 2.86🩺 Clinique
Maintenance and tolerability of infliximab in a cohort of 152 patients with rheumatoid arthritis
Clinical and experimental rheumatology · 2008 · Journal Article
Figueiredo IT, Morel J, Sany J, Combe B
📚 17 cit.🔬→🩺 Translationnel
Efficacy and safety of combination etanercept and methotrexate versus etanercept alone in patients with rheumatoid arthritis with an inadequate response to methotrexate: the ADORE study
Annals of the rheumatic diseases · 2006 · Journal Article
van Riel PL, Taggart AJ, Sany J, Gaubitz M, et al.
📚 111 cit.🎯 RCR 3.12🩺 Clinique
Primary cutaneous Nocardia otitidiscaviarum infection in a patient with rheumatoid arthritis treated with infliximab
The Journal of rheumatology · 2005 · Case Reports
Fabre S, Gibert C, Lechiche C, Jorgensen C, et al.
📚 26 cit.🔬→🩺 Translationnel
Visceral leishmaniasis infection in a rheumatoid arthritis patient treated with infliximab
Clinical and experimental rheumatology · 2005 · Case Reports
Fabre S, Gibert C, Lechiche C, Dereure J, et al.
📚 41 cit.🎯 RCR 1.11🔬→🩺 Translationnel
The efficiency of switching from infliximab to etanercept and vice-versa in patients with rheumatoid arthritis
Clinical and experimental rheumatology · 2005 · Journal Article
Cohen G, Courvoisier N, Cohen JD, Zaltni S, et al.
📚 74 cit.🎯 RCR 2.12🔬→🩺 Translationnel
Study of the tolerance of infliximab infusions with or without betamethasone premedication in patients with active rheumatoid arthritis
Annals of the rheumatic diseases · 2005 · Journal Article
Sany J, Kaiser MJ, Jorgensen C, Trape G
📚 42 cit.🎯 RCR 1.30🩺 Clinique
Outcomes of a multicentre randomised clinical trial of etanercept to treat ankylosing spondylitis
Annals of the rheumatic diseases · 2004 · Clinical Trial
Calin A, Dijkmans BA, Emery P, Hakala M, et al.
📚 250 cit.🎯 RCR 6.96🩺 Clinique
Efficacy and safety of adalimumab as monotherapy in patients with rheumatoid arthritis for whom previous disease modifying antirheumatic drug treatment has failed
Annals of the rheumatic diseases · 2004 · Clinical Trial
van de Putte LB, Atkins C, Malaise M, Sany J, et al.
📚 487 cit.🎯 RCR 12.50🩺 Clinique
Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: double-blind randomised controlled trial
Lancet (London, England) · 2004 · Clinical Trial
Klareskog L, van der Heijde D, de Jager JP, Gough A, et al.
📚 1413 cit.🎯 RCR 35.64🩺 Clinique
Secondary addition of methotrexate to partial responders to etanercept alone is effective in severe rheumatoid arthritis
Annals of the rheumatic diseases · 2004 · Letter
Cohen JD, Zaltni S, Kaiser MJ, Bozonnat MC, et al.
📚 9 cit.🔬→🩺 Translationnel
Effect of etanercept on tenosynovitis and nodules in rheumatoid arthritis
Arthritis and rheumatism · 2002 · Clinical Trial
Kaiser M-, Bozonnat M-, Jorgensen C, Daurès J-, et al.
📚 19 cit.🩺 Clinique
Efficacy of infliximab (Remicade) in the treatment of spondyloarthropathies. two case reports
Joint bone spine · 2001 · Case Reports
Kaiser MJ, Sany J
📚 2 cit.

csDMARDs5

▼

Efficacy and safety of combination etanercept and methotrexate versus etanercept alone in patients with rheumatoid arthritis with an inadequate response to methotrexate: the ADORE study
Annals of the rheumatic diseases · 2006 · Journal Article
van Riel PL, Taggart AJ, Sany J, Gaubitz M, et al.
📚 111 cit.🎯 RCR 3.12🩺 Clinique
Leflunomide-induced aseptic meningitis
Joint bone spine · 2004 · Case Reports
Cohen JD, Jorgensen C, Sany J
📚 14 cit.
Therapeutic effect of the combination of etanercept and methotrexate compared with each treatment alone in patients with rheumatoid arthritis: double-blind randomised controlled trial
Lancet (London, England) · 2004 · Clinical Trial
Klareskog L, van der Heijde D, de Jager JP, Gough A, et al.
📚 1413 cit.🎯 RCR 35.64🩺 Clinique
Secondary addition of methotrexate to partial responders to etanercept alone is effective in severe rheumatoid arthritis
Annals of the rheumatic diseases · 2004 · Letter
Cohen JD, Zaltni S, Kaiser MJ, Bozonnat MC, et al.
📚 9 cit.🔬→🩺 Translationnel
Folic acid alters methotrexate availability in patients with rheumatoid arthritis
The Journal of rheumatology · 2000 · Clinical Trial
Bressolle F, Kinowski JM, Morel J, Pouly B, et al.
📚 14 cit.🩺 Clinique

Qualité de vie / PROMs2

▼

Disease status, costs and quality of life of patients with rheumatoid arthritis in France: the ECO-PR Study
Joint bone spine · 2008 · Journal Article
Kobelt G, Woronoff AS, Richard B, Peeters P, et al.
📚 59 cit.🎯 RCR 1.98🔬→🩺 Translationnel
Preliminary evaluation of medical outcomes (including quality of life) and costs in incident RA cases receiving hospital-based multidisciplinary management
Joint bone spine · 2000 · Evaluation Study
Maravic M, Bozonnat MC, Sevezan A, Gasqueres D, et al.
📚 19 cit.🔬→🩺 Translationnel

Lupus1

▼

Polymorphism of HLA-DMA and DMB alleles in patients with systemic lupus erythematosus
The Journal of rheumatology · 2003 · Comparative Study
Morel J, Simoes Cda S, Avinens O, Sany J, et al.
📚 9 cit.

Recommandations1

▼

WHO Collaborating Centre consensus meeting on anti-cytokine therapy in rheumatoid arthritis
Rheumatology (Oxford, England) · 2001 · Journal Article
Emery P, Reginster JY, Appelboom T, Breedveld FC, et al.
📚 39 cit.🎯 RCR 1.06🔬→🩺 Translationnel

Datasets & protocoles partagés

Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).

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