📇 Rhumatologue · FORT DE FRANCE CEDEX · (972) · Hospitalier
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2 raisons identifiées
Plateau technique de référence
Centre hospitalier universitaire (CHU) — équipements et expertise pointus pour les cas complexes
Délais de RDV courts dans la région
106.4 rhumatos / 100 000 hab. — département bien doté
✨ Génération du profil synthétique IA en cours…
CHU DE MARTINIQUE SITE P.ZOBDA QUITMAN
QUA LA MEYNARD CS 90632, 97261 FORT DE FRANCE CEDEX
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
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Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
BMC pulmonary medicine · 2022
Abstract Background Thoracic multidetector computed tomography (MDCT) is essential for the detection of interstitial lung disease (ILD) in patients with systemic sclerosis (SSc). Thoracic MDCT assessment can reveal the presence of thoracic lymphadenopathies (LAP) whose signification remains uncertain. The purpose of the study was to describe the characteristics and to assess the significance of thoracic LAP in patients with diffuse SSc. Methods We conducted a monocentric observational study on adult patients with diffuse SSc, and collected general patient and first thoracic MDCT characteristics, PET-CT and outcome data. Comparisons were made between patients with and without thoracic LAP. Results Forty-eight patients were included. There were 30 patients (62.5%) with an ILD and 23 (48%) with at least one thoracic LAP on the first MDCT assessment. Median number per patient of thoracic LAP was 3 [1–8], with a mean size of 11.7 ± 1.7 mm, mainly located in right para-tracheal area (22.8% of the total number of LAP), right hilar area (20.3%), left hilar area (6.5%), and sub-carinal area (15.2%). PET-CT showed lymph node hypermetabolism in 11/15 patients (73.3%) with mean SUVmax at 4 ± 1.3. There were significantly more males (p = 0.002) and more patients exposed to silica (p = 0.001) in patients with thoracic LAP. ILD was significantly more extended according to Goh score (p = 0.03), and using semi-quantitative score for mixed ground-glass reticulation (p = 0.01) and global abnormalities (p = 0.03) in patients with thoracic LAP and ILD. Thirteen patients (27.1%) died during follow-up without significant difference according to the presence or not of thoracic LAP (p = 0.15). There was also no significant difference concerning immunosuppressive treatment initiation (p = 0.17). Conclusions Thoracic LAP are common in diffuse SSc and are generally multiple, not bulky, moderately hypermetabolic, and located at the base of the mediastinum lymph node chains. Their presence correlates with the extent of ILD. In absence of ILD, thoracic LAP presence seems to be often explained by silica exposure. Trial Registration: NA.
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Soins; la revue de reference infirmiere · 1987 · Journal Article
Humbert P, Renaud A, Dupond JL
Soins; la revue de reference infirmiere · 1987 · Journal Article
Dupond JL, Humbert P, Renaud A
Soins; la revue de reference infirmiere · 1987 · Journal Article
Humbert P, Dupond JL, Renaud A
BMC pulmonary medicine · 2022 · Journal Article
Renaud A, Pautre R, Morla O, Achille A, et al.