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2 raisons identifiées
Praticien-chercheur
10 articles scientifiques publiés — formation continue solide
Délais de RDV courts dans la région
107.5 rhumatos / 100 000 hab. — département bien doté
✨ Génération du profil synthétique IA en cours…
Indicateurs publics agrégés sur 250 M+ d'œuvres scientifiques (OpenAlex, PubMed). Traduits ici en langage patient.
Influence scientifique
Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.
9
9 articles ont été cités au moins 9fois par d'autres chercheurs — preuve que ses travaux sont repris par la communauté médicale.
h-index
Total citations reçues
271
Nombre de fois où d'autres équipes ont mentionné ses publications dans leurs propres travaux.
Publications totales
20
Articles, revues et chapitres référencés dans les bases académiques internationales.
Articles influents
9
Publications ayant marqué leur domaine — chacune citée au moins 10 fois par d'autres chercheurs.
i10-index
Thématiques principales
Affiliations FR : Centre Hospitalier Public du Cotentin
Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.
Articles déposés en accès libre sur l'archive ouverte des universités françaises (HAL) — gage d'activité de recherche en France.
Spironolactone in patients on chronic haemodialysis at high risk of adverse cardiovascular outcomes (ALCHEMIST): a multicentre, double-blind, randomised, placebo-controlled trial and updated meta-analysis
2025ArticleThe Lancet
Low incidence of SARS-CoV-2, risk factors of mortality and the course of illness in the French national cohort of dialysis patients
2020ArticleKidney International
Long-term effects of citric acid-based bicarbonate haemodialysis on patient outcomes: a survival propensity score–matched study in western France
2020ArticleNephrology Dialysis Transplantation
Grams ME, Sang Y, Ballew SH, et al, for the Chronic Kidney Disease Prognosis Consortium. Predicting timing of clinical outcomes in patients with chronic kidney disease and severely decreased glomerular filtration rate. Kidney Int. 2018;93:1442–1451
2018ArticleKidney International
An open-label randomized controlled trial of low-dose corticosteroid plus enteric-coated mycophenolate sodium versus standard corticosteroid treatment for minimal change nephrotic syndrome in adults (MSN Study)
2018ArticleKidney International
Acute and chronic nephropathy induced by fluindione must be addressed.
2012ArticleNephrology Dialysis Transplantation
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
CHPC - SITE CHERBOURG
46 R DU VAL DE SAIRE BP 208, 50102 CHERBOURG OCTEVILLE CEDEX
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2002
Journal of cell science · 2002
It has been reported that vimentin, a cytoskeleton filament that is expressed only in mesenchymal cells after birth, is re-expressed in epithelial cells in vivo under pathological conditions and in vitro in primary culture. Whether vimentin re-expression is only a marker of cellular dedifferentiation or is instrumental in the maintenance of cell structure and/or function is a matter of debate. To address this issue, we used renal proximal tubular cells in primary culture from vimentin-null mice (Vim-/-) and from wild-type littermates (Vim+/+). The absence of vimentin did not affect cell morphology, proliferation and activity of hydrolases, but dramatically decreased Na-glucose cotransport activity. This phenotype was associated with a specific reduction of SGLT1 protein in the detergent-resistant membrane microdomains (DRM). In Vim+/+cells, disruption of these microdomains by methyl-β-cyclodextrin decreased SGLT1 protein abundance in DRM, a change that was paralleled by a decrease of Na-glucose transport activity. Importantly, we showed that vimentin is located to DRM, but it disappeared after methyl-β-cyclodextrin treatment. In Vim-/- cells,supplementation of cholesterol with cholesterol-methyl-β-cyclodextrin complexes completely restored Na-glucose transport activity. Interestingly,neither cholesterol content nor cholesterol metabolism changed in Vim-/- cells. Our results are consistent with the view that re-expression of vimentin in epithelial cells could be instrumental to maintain the physical state of rafts and, thus, the function of DRM-associated proteins.
The International journal of artificial organs · 2016
Introduction The recent analysis of 4 randomized controlled trials has confirmed the lower mortality risk for postdilution online hemodiafiltration (OL-HDF) compared to hemodialysis, and above all for patients with the highest delivered body surface area standardized convective volume (CV/BSA >23 L/1.73 m 2 /session). Since the impact of the dialyzers used in these trials has never been studied, we retrospectively analyzed clinical tests carried out with 19 commonly used dialyzers. The aim was to provide information on their performances and behavior to aid in an objective choice for therapies associated with OL-HDF. Methods “Efficiency” was evaluated by measuring the reduction ratio of beta-2 microglobulin (RRß2M) and myoglobin (RRmyo) for a CV/BSA between 0 and 30 L, extrapolating them at CV/BSA = 23 L “Safety” was defined by the safe CV (CVsafe), corresponding to the CV/BSA above which albumin loss is >5 g/session. Results: With CV/BSA = 23 L, all the dialyzers ensure an optimal ß2M extraction (RRß2M: 76%–84.5%). For myoglobin, efficiency disparities are bigger (RRmyo: 40%–85%). Above all, 4/19 dialyzers lose more than 5 g albumin and should not be used under these conditions. Conclusions It is recommended to prescribe dialyzers that are above all safe. Moreover, if one considers that the removal of middle molecule solutes prevails over the CV necessary for their transmembrane transport, some dialyzers that are more efficient with CV/BSA <23 L than others with CV/BSA >= 23 L might then be prescribed when the conditions do not permit the suggested CV/BSA goal to be achieved.
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2020 · Journal Article
Potier J, Dolley-Hitze T, Hamel D, Landru I, et al.
Nephrologie & therapeutique · 2019 · Case Reports
Beaumier M, Roger H, Sauneuf B, Dugardin F, et al.
The International journal of artificial organs · 2016 · Journal Article
Potier J, Queffeulou G, Bouet J
PloS one · 2016 · Journal Article
Audemard-Verger A, Martin Silva N, Verstuyft C, Costedoat-Chalumeau N, et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2012 · Journal Article
Cam G, Kwetcheu AT, Vigneau C, Siohan P, et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2002 · Case Reports
Philit JB, Queffeulou G, Walker F, Gubler MC, et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2002 · Journal Article
Mercadal L, Montcel ST, Nochy D, Queffeulou G, et al.
Journal of cell science · 2002 · Comparative Study
Runembert I, Queffeulou G, Federici P, Vrtovsnik F, et al.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis · 2002 · Journal Article
Vrtovsnik F, Porcher R, Michel C, Hufnagel G, et al.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 1998 · Case Reports
Queffeulou G, Berenbaum F, Michel C, Mougenot B, et al.