📇 Rhumatologue · FORT DE FRANCE CEDEX · (972) · Mixte

M SERGE PIERRE-LOUIS

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Plateau technique de référence
Centre hospitalier universitaire (CHU) — équipements et expertise pointus pour les cas complexes
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9 articles scientifiques publiés — formation continue solide
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2 lieux d'exercice — choisissez celui qui vous arrange
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106.4 rhumatos / 100 000 hab. — département bien doté

Rhumatologue

📍 FORT DE FRANCE CEDEX (972)MixteRPPS 10001655116

🇫🇷 Publications académiques françaises (6)

✨ Génération du profil synthétique IA en cours…

Publications académiques en France

Articles déposés en accès libre sur l'archive ouverte des universités françaises (HAL) — gage d'activité de recherche en France.

Management of Major Orthopaedic Surgery in a Patient With the Rare Thrombomodulin c.1611C>a Mutation: A Case of an Uncommon Bleeding Disorder
2025
Article

Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.

Top publications · les plus citées

Hepatitis C virus (HCV) genotypes in the Caribbean island of Martinique: evidence for a large radiation of HCV-2 and for a recent introduction from Europe of HCV-4

Journal of clinical microbiology · 2004

📚 39 citations🎯 RCR 1.15🔓 Open Access

Lire l'abstract Crossref ↓

ABSTRACTMolecular epidemiological studies of hepatitis C virus (HCV) in the Caribbean may help to specify the origin and spread of HCV infection. Indeed, the Caribbean population is intermixed from European and African origins and geographically close to the American continent. We characterized HCV genotypes in the Caribbean island of Martinique. HCV genotypes were analyzed by sequencing or reverse hybridization in the 5′ noncoding region (5′NC) in 250 HCV-monoinfected and 85 HCV-human immunodeficiency virus (HIV)-coinfected patients. In addition, sequencing in the nonstructural 5B (NS5B) gene was required to determine the subtype or to perform phylogenetic analysis in selected samples. Genotypes 1 to 6 were found, respectively, in 84.4, 6.8, 5.2, 2.8, 0.4, and 0.4% of 250 HCV-monoinfected patients and in 71.7, 7.1, 15.3, 5.9, 0, and 0% of 85 HCV-HIV-coinfected patients. HCV-1b was found in 66.4% of the HCV-monoinfected patients and was associated with blood transfusion, whereas HCV-1a was detected in 41.2% of the HCV-HIV-coinfected patients and was associated with intravenous drug use (IVDU). The HCV-3 strains belonged to subtype 3a and were linked to IVDU. Phylogenetic analyses were focused on HCV-2 and HCV-4, which are common in Africa. Two opposite patterns were evidenced.NS5Bsequences from 19 HCV-2 isolates were affiliated with many different subtypes described either in Europe or in West Africa, suggesting an ancient radiation. In contrast, seven of the nine HCV-4NS5Bsequences ranged within HCV-4a and HCV-4d clusters spreading in continental France by the IVDU route. Epidemiological data demonstrate the recent introduction of HCV-4a and -4d subtypes into the Caribbean.

Seizure control and side-effect profile after switching adult epileptic patients from standard to extended-release divalproex sodium

Clinical neurology and neurosurgery · 2009

📚 12 citations🩺 Clinique

Study of HLA antigens in systemic lupus erythematosus in the French West Indies

Tissue antigens · 1988

📚 6 citations

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As incidence of SLE is high in Blacks, we studied HLA and SLE associations in the French West Indies, whose population is racially mixed. Forty‐seven coloured SLE patients have been typed in HLA A, B, C and DR. We observed B8 association in nearly all of the studies. B15 association, more frequent in Caucasians, was found, also B53 association, a Black variant of B5 more frequent in Blacks. We did not find any class II association.

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M SERGE PIERRE-LOUIS

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Publications académiques en France

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Top publications · les plus citées

Publications scientifiques (9) — classées par pathologie

Transversal8

Lupus1

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