Docteur LAURENCE PAOLOZZI

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Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).

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Top publications · les plus citées

• 1

  Clinical profile, contemporary management and one-year mortality in patients with severe acute heart failure syndromes: The EFICA study

  European journal of heart failure · 2006

  📚 256 citations🎯 RCR 6.82Top 5% NIH

  Lire l'abstract Crossref ↓

  Abstract Background Little is known about the epidemiology of acute decompensated heart failure (ADHF) in patients admitted to intensive and coronary care units (ICU/CCU). Observational data may improve disease management and guide the design of clinical trials. Aims EFICA is an observational study of the clinical profile, management and survival of ADHF patients admitted to ICU/CCU. Methods The study included 599 patients admitted to 60 ICU/CCUs across France. Relevant data was recorded during hospitalisation. Survival was assessed at 4 weeks and 1 year. Results The main cause of ADHF was ischaemic heart disease (61%); 29% of patients had cardiogenic shock. Mortality was 27.4% at 4 weeks and 46.5% at 1 year, increasing to 43.2% and 62.5%, respectively, when including pre-admission deaths. Shock patients had the highest [57.8% vs. 15.2% without shock (p<0.001)] and patients with hypertension and pulmonary oedema had the lowest 4-week mortality: (7%). Pre-admission NYHA class III–IV heart failure, not initial clinical presentation, influenced 1-year mortality. Conclusion ADHF is a heterogeneous syndrome. Based on initial clinical presentation, three entities with distinct features and outcome may be described: cardiogenic shock, pulmonary oedema with hypertension, and ‘decompensated’ chronic heart failure. This should be taken into account in future observational studies, guidelines and clinical trials.

• 2

  Etanercept 50 mg once weekly is as effective as 25 mg twice weekly in patients with ankylosing spondylitis

  Annals of the rheumatic diseases · 2006

  📚 104 citations🎯 RCR 2.97Top 16% NIH🩺 Clinique🔓 Open Access
• 3

  Evaluation of the symptomatic and structural efficacy of a new hyaluronic acid compound, NRD101, in comparison with diacerein and placebo in a 1 year randomised controlled study in symptomatic knee osteoarthritis

  Annals of the rheumatic diseases · 2004

  📚 104 citations🎯 RCR 3.28Top 14% NIH🩺 Clinique🔓 Open Access📄 PDF gratuit ↗

Publications scientifiques (14) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

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