📇 Rhumatologue · POITIERS · (86) · Salarié
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Auteur de référence en rhumatologie
24 articles scientifiques publiés — un praticien à la pointe de la recherche
Délais de RDV courts dans la région
124.6 rhumatos / 100 000 hab. — département bien doté
✨ Génération du profil synthétique IA en cours…
CDS - SERVICE DE SANTÉ ETUDIANTE - SSE
CAMPUS UNIVERSITAIRE - BAT. C 4 4 ALL JEAN MONNET, 86000 POITIERS
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Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
BMC genomics · 2013
Abstract Background Aspartic proteases (APs) are a large family of proteolytic enzymes found in almost all organisms. In plants, they are involved in many biological processes, such as senescence, stress responses, programmed cell death, and reproduction. Prior to the present study, no grape AP gene(s) had been reported, and their research on woody species was very limited. Results In this study, a total of 50 AP genes (VvAP) were identified in the grape genome, among which 30 contained the complete ASP domain. Synteny analysis within grape indicated that segmental and tandem duplication events contributed to the expansion of the grape AP family. Additional analysis between grape and Arabidopsis demonstrated that several grape AP genes were found in the corresponding syntenic blocks of Arabidopsis, suggesting that these genes arose before the divergence of grape and Arabidopsis. Phylogenetic relationships of the 30 VvAPs with the complete ASP domain and their Arabidopsis orthologs, as well as their gene and protein features were analyzed and their cellular localization was predicted. Moreover, expression profiles of VvAP genes in six different tissues were determined, and their transcript abundance under various stresses and hormone treatments were measured. Twenty-seven VvAP genes were expressed in at least one of the six tissues examined; nineteen VvAPs responded to at least one abiotic stress, 12 VvAPs responded to powdery mildew infection, and most of the VvAPs responded to SA and ABA treatments. Furthermore, integrated synteny and phylogenetic analysis identified orthologous AP genes between grape and Arabidopsis, providing a unique starting point for investigating the function of grape AP genes. Conclusions The genome-wide identification, evolutionary and expression analyses of grape AP genes provide a framework for future analysis of AP genes in defining their roles during stress response. Integrated synteny and phylogenetic analyses provide novel insight into the functions of less well-studied genes using information from their better understood orthologs.
The Annals of thoracic surgery · 2006
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Cureus · 2025 · Case Reports
C P, Ann Jose J, Verma G, Priya V L, et al.
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Ramanan A, Balasubramanian V, C R, Sami P
JBJS case connector · 2024 · Case Reports
C A, Raju A, Meleppuram JJ, Nair AV, et al.
Journal of orthopaedic case reports · 2016 · Case Reports
Nekkanti S, C V, Js ST, R R, et al.
Journal of orthopaedic case reports · 2016 · Case Reports
Ay GR, D SR, T C, C K, et al.
La Tunisie medicale · 2005 · Case Reports
Aïda AK, Sana BS, Essia S, Carole GB, et al.
Advances in protein chemistry and structural biology · 2026 · Journal Article
Loganathan T, Madhulekha S, Zayed H, C GPD
Lupus · 2023 · Journal Article
Patil A, Shobha V, Shenoy P, S C, et al.
Cureus · 2019 · Case Reports
Thomas M, Robert A, Kuruvilla N, C U
Current genomics · 2014 · Journal Article
J de AS, C A, P SG, S C
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2025 · Journal Article
G A, C G, C J M, B L, et al.
Annals of the rheumatic diseases · 2023 · Letter
C SK, Ahmed S, Shenoy V, Menon AR, et al.
Le Mali medical · 2022 · English Abstract
Kouakou BDM, Konaté I, Florent KA, Bonfils KKP, et al.
Critical care nursing clinics of North America · 2003 · Journal Article
Sendelbach S, Carole L, Lapensky J, Kshettry V
Vaccine · 2026 · Journal Article
Stefania B, Flavia P, Antonio P, Emanuele P, et al.
Cureus · 2024 · Case Reports
Ramanan A, Balasubramanian V, C R, Sami P
Journal of orthopaedic case reports · 2016 · Case Reports
Nekkanti S, C V, Js ST, R R, et al.
L'Encephale · 2022 · English Abstract
Bergheul S, Carole C, Augustin E, Oscar L, et al.
BMC health services research · 2022 · Journal Article
Winifred AD, Jane RL, Brian K, Amponsah-Tawiah K, et al.
Psychological reports · 2021 · Journal Article
Elise B, Eynde SV, Egée N, Lamotte M, et al.
BMC genomics · 2013 · Journal Article
Guo R, Xu X, Carole B, Li X, et al.
Biochimie · 1999 · Journal Article
Dassain M, Leroy A, Colosetti L, Carolé S, et al.
European journal of pediatrics · 2024 · Journal Article
Yıldız Ç, Küçükali B, C SSB, Şenol PE, et al.
European journal of pediatrics · 2024 · Journal Article
Yıldız Ç, Küçükali B, C SSB, Şenol PE, et al.
The Annals of thoracic surgery · 2006 · Comparative Study
Kshettry VR, Carole LF, Henly SJ, Sendelbach S, et al.
Vaccine · 2026 · Journal Article
Stefania B, Flavia P, Antonio P, Emanuele P, et al.
Cureus · 2025 · Case Reports
Lakshme I, C A, Senthil N, Pandurangan V
Cureus · 2026 · Case Reports
R S, Nanda M S, Adalarasan S, Subramanian Y, et al.