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Docteur CLAUDE MARREQUESTE

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1 raison identifiée

  • Auteur de référence en rhumatologie

    50 articles scientifiques publiés — un praticien à la pointe de la recherche

Rhumatologue
RPPS 10002854577

Diplômes

🎓 DES & spécialité ordinale

  • Rhumatologie (SM)

📚 CES (Certificat d'Études Spéciales)

  • CES Rhumatologie

🎓 Diplômes

  • DE Docteur en médecine

Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.

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Top publications · les plus citées

  • 1
    The emergence and diversification of dog morphology

    Science (New York, N.Y.) · 2025

    📚 4 citations🔓 Open Access📄 PDF gratuit ↗
    Lire l'abstract Crossref ↓

    Dogs exhibit an exceptional range of morphological diversity as a result of their long-term association with humans. Attempts to identify when dog morphological variation began to expand have been constrained by the limited number of Pleistocene specimens, the fragmentary nature of remains, and difficulties in distinguishing early dogs from wolves on the basis of skeletal morphology. In this study, we used three-dimensional geometric morphometrics to analyze the size and shape of 643 canid crania spanning the past 50,000 years. Our analyses show that a distinctive dog morphology first appeared at about 11,000 calibrated years before present, and substantial phenotypic diversity already existed in early Holocene dogs. Thus, this variation emerged many millennia before the intense human-mediated selection shaping modern dog breeds beginning in the 19th century.

  • 2
    Using CE to confirm the activity of fluorescent miRFP670-LIMK1 protein produced for MST assays directly in cell lysate

    Analytica chimica acta · 2025

    📚 3 citations🔓 Open Access
  • 3
    Re-assessment of the risks to public health related to the genotoxicity of styrene present in plastic food contact materials

    EFSA journal. European Food Safety Authority · 2025

    📚 3 citations🔓 Open Access
    Lire l'abstract Crossref ↓

    Abstract The EFSA Panel on Food Contact Materials (FCM) was requested by the European Commission to re‐evaluate the potential genotoxicity of styrene after oral exposure and its safety for use in plastic FCM with a specific migration limit (SML) of 40 μg/kg food. A rigorous assessment of the in vivo genotoxicity studies (i) provided by third parties, (ii) identified by a targeted literature search and (iii) reported in the 2019 IARC Monograph was performed. All studies were assessed for reliability and relevance and the results integrated in the weight of evidence. The results provided by reliable in vivo oral genotoxicity studies, covering different genetic endpoints and target tissues, including liver, the primary site of metabolism, demonstrated that the oral administration of styrene in mice and rats up to the maximum tolerated dose (300 and 500 mg/kg body weight (bw), respectively) did not induce genotoxic effects. The Panel concluded that there was no evidence that styrene is genotoxic following oral exposure. For substances demonstrated to be non‐genotoxic, according to the EFSA Note for Guidance for FCM, an SML up to 50 μg/kg food would not be of safety concern. Consequently, the use of styrene in the manufacture of FCM respecting the SML of 40 μg/kg food proposed by the European Commission is not of safety concern.

Publications scientifiques (50) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

Transversal32

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Pharmacovigilance4

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Revue générale4

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Pédiatrie3

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Génétique2

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Biothérapies non-anti-TNF1

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Case report / série1

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Épidémiologie & registres1

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Essai clinique1

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Revue / méta-analyse1

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SAPL1

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Vascularites des gros vaisseaux1

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