Docteur FABIENNE LOUIS-SIDNEY

Thèses universitaires

• Pathologies rhumatologiques en population afro-descendante : exemple de la Martinique

  Recherche clinique, innovation technologique, sante publique🎓 Antilles

  Direction : Moustapha Dramé, Christophe Deligny

Source : catalogue national des thèses theses.fr (ABES). Ne couvre que les doctorats / HDR — les thèses d'exercice (DES) sont archivées dans les SCD universitaires.

Bibliographie

• Behçet’s Disease In Children And Adults Of Sub-Saharan Ancestry: A Systematic Review And Meta-Analysis

  2025

  ArticleClinical Reviews in Allergy & Immunology

• Lifetime clinical presentation of Still's disease in the Afro-descendant population of the French West Indies

  2025

  ArticleJoint Bone Spine

• Correspondence on “Epidemiology of rheumatic diseases in tropical populations” by Goyal andamp- Santhanam

  2025

  ArticleBest Practice and Research: Clinical Rheumatology

• 52431 Characteristics of adult-onset Still's disease eruption in individuals of African ancestry

  2024

  ArticleJournal of The American Academy of Dermatology

• Ethnicity also influences the clinical heterogeneity of mixed connective tissue disease of childhood onset: The French West Indies experience

  2024

  ArticleAutoimmunity Reviews

• Atteinte sévère de l’intestin grêle et pseudo-obstruction intestinale chronique au cours de la sclérodermie systémique : bases physiopathologiques, diagnostiques et thérapeutiques, dont la nutrition parentérale

  2024

  ArticleLa Revue de Médecine Interne

• Longitudinal follow-up of mixed connective tissue disease and overlapping autoimmune diseases of childhood onset in the Afro-descendant population of the French West Indies

  2024

  ArticlePediatric Rheumatology

• Juvenile Dermatomyositis in Afro-Caribbean children: a cohort study in the French West Indies

  2023

  ArticlePediatric Rheumatology

Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).

Lieu de consultation

• CHU DE MARTINIQUE SITE P.ZOBDA QUITMAN

  Quartier LA MEYNARD, 97261 Fort-de-France

  ☎ 0596552000Hospitalier🏥 Centre CHU ↗🏥 Voir cet établissement

Tarifs & secteur de conventionnement

Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).

Prendre rendez-vous & contact

Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Articles de presse (1)

Source : Google News (recherche par nom complet — homonymes possibles, vérifier le contenu).

• Trois étudiants majors en médecine honorés - martinique.franceantilles.fr

  📰 martinique.franceantilles.fr · 09/11/2014

  <a href="https://news.google.com/rss/articles/CBMitAFBVV95cUxNTG5jM3Y2TW5JQ2VQb0FHTXE3TW9zTXkzQlBQQ21JSTVyMVdlMkE4bVFobUhWOWpzajVaaWxnYmUyUW1EclU4UzVHZU9zNzZsSW0xRmRuX1pOQUNOT3dRblpWcHZHS3BCaWptRzBiTUtlUzZfQmR3MUtaM0NDZ0U2bUY0SkZZQ2FUZ1c3a0NpY1ExNmRXTFIyNUdQNkI4NG1rUEFKLU8zVmtXVTg4Q0lWeExfN0M?oc=5"

Top publications · les plus citées

• 1

  A Risk Score to Detect Subclinical Rheumatoid Arthritis-Associated Interstitial Lung Disease

  Arthritis & rheumatology (Hoboken, N.J.) · 2022

  📚 83 citations🎯 RCR 9.25Top 3% NIH🔓 Open Access📄 PDF gratuit ↗

  Lire l'abstract Crossref ↓

  ObjectivePatients at high risk of rheumatoid arthritis–associated interstitial lung disease (RA‐ILD) would benefit from being identified before the onset of respiratory symptoms; this can be done by screening patients with the use of chest high‐resolution computed tomography (HRCT). Our objective was to develop and validate a risk score for patients who have subclinical RA‐ILD.MethodsOur study included a discovery population and a replication population from 2 prospective RA cohorts (ESPOIR and TRANSLATE2, respectively) without pulmonary symptoms who had received chest HRCT scans. All patients were genotyped for MUC5B rs35705950. After multiple logistic regression, a risk score based on independent risk factors for subclinical RA‐ILD was developed in the discovery population and tested for validation in the replication population.ResultsThe discovery population included 163 patients with RA, and the replication population included 89 patients with RA. The prevalence of subclinical RA‐ILD was 19.0% and 16.9%, respectively. In the discovery population, independent risk factors for subclinical RA‐ILD were presence of the MUC5B rs35705950 T allele (odds ratio [OR] 3.74 [95% confidence interval (95% CI) 1.37, 10.39]), male sex (OR 3.93 [95% CI 1.40, 11.39]), older age at RA onset (for each year, OR 1.10 [95% CI 1.04, 1.16]), and increased mean Disease Activity Score in 28 joints using the erythrocyte sedimentation rate (for each unit, OR 2.03 [95% CI 1.24, 3.42]). We developed and validated a derived risk score with receiver operating characteristic areas under the curve of 0.82 (95% CI 0.70–0.94) for the discovery population and 0.78 (95% CI 0.65–0.92) for the replication population. Excluding MUC5B rs35705950 from the model provided a lower goodness of fit (likelihood ratio test, P = 0.01).ConclusionWe developed and validated a risk score that could help identify patients at high risk of subclinical RA‐ILD. Our findings support an important contribution of MUC5B rs35705950 to subclinical RA‐ILD risk.

• 2

  Systemic juvenile idiopathic arthritis in French Afro-Caribbean children, a retrospective cohort study

  Pediatric rheumatology online journal · 2022

  📚 10 citations🎯 RCR 1.13🔓 Open Access📄 PDF gratuit ↗

  Lire l'abstract Crossref ↓

  Abstract Introduction The epidemiology and clinical presentation of systemic juvenile idiopathic arthritis (sJIA) in the Afro-Caribbean population is not well described. Methods Retrospective study conducted between January 2000 and January 2022 in the French Overseas Departments of America. Clinical data were obtained from multiple sources: computerized hospital archives, registries of referring pediatricians, and the French National Registry for rare diseases. The disease studied was sJIA defined according to international criteria. Results Twenty-five patients were identified. Mean age at diagnosis was 7.5 years (range: 1.2—14.9 years) and mean duration of follow-up was 5.2 years (range: 0.5—16 years). All patients had joint involvement at diagnosis with 68% presenting inflammatory arthritis and 32% inflammatory joint pain. Sixteen percent had coronary involvement at onset. More than half (52%) suffered from macrophage activation syndrome (MAS) during childhood (32% at onset). The mean number of flares in childhood was 2 (Range: 1—5). Sixty-eight percent of patients had disease control during childhood without biotherapy. The most frequent second line treatment was anakinra (7/8). There was no difference in clinical or biological severity according to gender. The median duration of treatment during childhood was 5 months (range: 2—144) and 72% had a cumulative treatment duration of less than one year. Conclusion These patients of Afro-Caribbean origin suffering from sJIA showed some specificities, such as a higher rate of MAS and coronary involvement at onset. The incidence per year was stable over a 20-year period. Overall outcomes during childhood were similar to western countries.

• 3

  Good Long-Term Prognosis of Lupus Nephritis in the High-Income Afro-Caribbean Population of Martinique with Free Access to Healthcare

  Journal of clinical medicine · 2022

  📚 10 citations🎯 RCR 1.13🔓 Open Access📄 PDF gratuit ↗

  Lire l'abstract Crossref ↓

  Lupus nephritis (LN) has been described as having worse survival and renal outcomes in African-descent patients than Caucasians. We aimed to provide long-term population-based data in an Afro-descendant cohort of LN with high income and easy and free access to specialized healthcare. Study design: We performed a retrospective population-based analysis using data from 2002–2015 of 1140 renal biopsies at the University Hospital of Martinique (French West Indies). All systemic lupus erythematosus patients with a diagnosis of LN followed for at least 12 months in Martinique or who died during this period were included. Results: A total of 89 patients were included, of whom 68 (76.4%) had proliferative (class III or IV), 17 (19.1%) had membranous (class V), and 4 (4.5%) had class I or II lupus nephritis according to the ISN/RPS classification. At a mean follow-up of 118.3 months, 51.7% of patients were still in remission. The rates of end-stage renal disease were 13.5%, 19.1%, and 21.3% at 10, 15, and 20 years of follow-up, respectively, and mortality rates were 4.5%, 5.6%, and 7.9% at 10, 15, and 20 years of follow-up, respectively. Conclusions: The good survival of our Afro-descendant LN patients, similar to that observed in Caucasians, shades the burden of ethnicity but rather emphasizes and reinforces the importance of optimizing all modifiable factors associated with poor outcome, especially socioeconomics.

Publications scientifiques (15) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

Datasets & protocoles partagés

• Juvenile Dermatomyositis in Afro-Caribbean children: a cohort study in the French West Indies

  Collection2024figshare

  Abstract Introduction The epidemiology of Juvenile Dermatomyositis (JDM) in non-Caucasian population is poorly described. We performed a study of patients followed up in the French West Indies for JDM. We aimed to descri

• Juvenile Dermatomyositis in Afro-Caribbean children: a cohort study in the French West Indies

  Collection2024figshare

  Abstract Introduction The epidemiology of Juvenile Dermatomyositis (JDM) in non-Caucasian population is poorly described. We performed a study of patients followed up in the French West Indies for JDM. We aimed to descri

• Longitudinal follow-up of mixed connective tissue disease and overlapping autoimmune diseases of childhood onset in the Afro-descendant population of the French West Indies

  Collection2024figshare

  Abstract Introduction Overlap autoimmune syndromes (OAS) and mixed connective tissue disease (MCTD) are rare in children. We performed a retrospective, longitudinal and descriptive study of Afro-Caribbean patients from t

• Longitudinal follow-up of mixed connective tissue disease and overlapping autoimmune diseases of childhood onset in the Afro-descendant population of the French West Indies

  Collection2024figshare

  Abstract Introduction Overlap autoimmune syndromes (OAS) and mixed connective tissue disease (MCTD) are rare in children. We performed a retrospective, longitudinal and descriptive study of Afro-Caribbean patients from t

Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).

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