Docteur CLEMENTINA LOPEZ MEDINA
121 publis sur 5 ans↘
✨ Profil synthétique
IA · 06/05/2026Le Docteur CLEMENTINA LOPEZ MEDINA est un rhumatologue avec une production scientifique significative, comme en témoignent ses 287 publications et un h-index de 25. Ses recherches se concentrent principalement sur les spondyloarthrites, l'arthrite rhumatoïde, le psoriasis, ainsi que les pathologies de la colonne vertébrale et les troubles auto-immuns. Ses travaux publiés sur PubMed couvrent l'épidémiologie, les spondyloarthrites, les traitements anti-IL-17 et anti-IL-23, ainsi que des aspects génétiques.
Expertises présumées
- Spondyloarthrite
- Arthrite rhumatoïde
- Psoriasis
- Pathologie de la colonne vertébrale
- Troubles auto-immuns
- Thérapies anti-IL-17
- Thérapies anti-IL-23
- Génétique des maladies rhumatismales
Synthèse automatique à partir des sources publiques (HAL, OpenAlex, theses.fr, ClinicalTrials.gov, FAI²R, ANS). Pas une évaluation clinique. Le médecin peut corriger via son compte.
Diplômes
🎓 DES & spécialité ordinale
- Rhumatologie (SM)
🎓 Diplômes
- Diplôme éq d'un pays de l'EEE profession Médecin
📝 Autres formations
- DEES Rhumatologie
Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.
Activité de recherche & publications
Source : bases de données publiques (OpenAlex, PubMed).
h-index
25
h articles cités ≥ h fois chacun. Un h de 25 = 25 publications avec 25+ citations.
Citations
3 139
Publications
287
i10-index
71
Thématiques principales
- Spondyloarthritis Studies and Treatments ×214
- Rheumatoid Arthritis Research and Therapies ×162
- Psoriasis: Treatment and Pathogenesis ×62
- Spine and Intervertebral Disc Pathology ×41
- Autoimmune and Inflammatory Disorders Research ×30
Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.
Bibliographie
Variability of Psoriatic Arthritis Impact of Disease questionnaire (PsAID12) thresholds in psoriatic arthritis: insights from the the observational ReFlaP study
2025ArticleRheumatology
Article published Joint Bone Spine Clinical enthesitis in patient with psoriatic arthritis, a systematic literature review with meta-analysis
2025ArticleJoint Bone Spine
Patient Profiles in Randomized Controlled Trials Versus a Real-World Study in Psoriatic Arthritis: Scoping Review and Metaanalysis
2025ArticleJournal of Rheumatology
Performance analysis of a deep-learning algorithm to detect the presence of inflammation in MRI of sacroiliac joints in patients with axial spondyloarthritis
2025ArticleAnnals of the Rheumatic Diseases
Ultrasonography for the assessment of enthesitis in psoriatic arthritis: systematic review with meta-analysis
2024ArticleRheumatology
Multi-domain effectiveness of guselkumab evaluated via composite indices through 1 year in patients with PsA and inadequate response to TNFi: post hoc analysis of COSMOS
2024ArticleRheumatology
Subclinical psoriatic arthritis and disease interception -where are we in 2024?
2024ArticleRheumatology
Disease activity and widespread pain are main contributors to patient-reported global health in axial spondyloarthritis: an analysis of 6064 patients
2024ArticleRheumatology International
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
Lieu de consultation
Tarifs & secteur de conventionnement
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Prendre rendez-vous & contact
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Top publications · les plus citées
- 1Subclinical psoriatic arthritis and disease interception-where are we in 2024?
Rheumatology (Oxford, England) · 2025
Lire l'abstract Crossref ↓
Abstract Psoriatic arthritis (PsA) is a chronic rheumatic disease that usually appears in patients with skin psoriasis, making it a model for detection of joint disease in the pre-clinical phases in a setting where therapy for cutaneous disease may ameliorate or prevent arthritis development. Such PsA prevention appears credible due to the increasingly recognized closely shared immunopathology between the skin and joints, especially the entheses. Recently, several initiatives have explored the concept of pre-clinical PsA, and nomenclatures have been developed with the recent EULAR nomenclature proposing a simplified three stages from psoriasis to clinical PsA development, namely at risk of PsA, subclinical PsA and early PsA. A better comprehension of early PsA and the identification of individuals predisposed to its development could enable interventions to ‘prevent’ the appearance of PsA. Several recent retrospective observational studies have demonstrated disease interception feasibility, i.e. treatment of people with psoriasis may prevent the appearance of PsA, in particular using biologic disease-modifying drugs. However, further data are urgently required due to unexpected findings in some studies where TNF inhibition for psoriasis does not reduce the rate of PsA development. In this review we address the current challenges in early PsA, including comparisons of pre-PsA nomenclature sets, its risk factors and the potential for disease interception.
- 2
- 3Ultrasonography for the assessment of enthesitis in psoriatic arthritis: systematic review with meta-analysis
Rheumatology (Oxford, England) · 2025
Lire l'abstract Crossref ↓
Abstract Objectives The specificity of US for enthesitis in PsA is unclear. The objective was to analyse the specificity of US enthesitis in Mode B and using power Doppler for the diagnosis of PsA through a systematic review with meta-analysis. Methods Systematic review in PubMed 2010 to June 2023 of studies of adult patients with confirmed PsA with or without a control group of non-PsA patients, reporting information on US enthesitis. Data were analysed on (i) the prevalence of US enthesitis (presence of at least one enthesitis) in PsA patients and non-PsA patients, (ii) specificity and sensitivity of US enthesitis and then specifically power Doppler for PsA diagnosis and (iii) most specific localizations of enthesitis in PsA patients. Pooled percentages and means were evaluated using univariate random effects meta-analysis. Results In 76 articles, 5927 patients with PsA were compared with 3423 controls (59.0% of whom had psoriasis). The prevalence of US enthesitis was 73.7% (95% CI 56.6–90.9%) in PsA patients vs 12.6% (2.6–22.3%) in controls. The pooled specificity and sensitivity of Mode B US were 73.2% (59.3–87.0%) and 62.1% (47.9–76.4%); and of power Doppler, were 97.9% (96.5–99.5%) and 14.7% (8.2–21.2%), respectively. The site most frequently involved in PsA but not in controls was the Achilles tendon, in which erosions and power Doppler activity were most discriminant. Conclusion In this systematic review, US enthesitis was highly prevalent in PsA patients. Evidencing enthesitis by US was found to be reasonably specific and could contribute to the diagnosis of PsA; power Doppler was highly specific, however it was rarely present.
Publications scientifiques (50) — classées par pathologie
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Transversal27
▼
Transversal27
▼- Frequency and characteristics of axial involvement in psoriatic arthritis: results from the International Multicentre AXIS Study
Annals of the rheumatic diseases · 2026 · Journal Article
Torgutalp M, Almodovar R, Azevedo VF, Baraliakos X, et al.
- Inflammatory protein profiling in immune cells identifies molecular signatures for enhanced diagnostic precision in psoriatic arthritis
Molecular biomedicine · 2026 · Journal Article
Martín-Salazar JE, Arias-de la Rosa I, López-Montilla MD, Ortiz-Buitrago P, et al.
- Development and validation of a Disease Activity index for PSoriatic Arthritis based on 44 joints (DAPSA44)
Annals of the rheumatic diseases · 2026 · Journal Article
Capelusnik D, Lopez-Medina C, van der Heijde D, Aletaha D, et al.
📚 1 cit.🔬→🩺 Translationnel - Transcriptomic and proteomic analysis stratifies patients with axial spondyloarthritis based on disease activity, structural damage and radiographic progression
RMD open · 2026 · Journal Article
Cuesta-López L, Arias-de la Rosa I, Pérez-Sánchez C, Barbera-Betancour A, et al.
- Global patterns and determinants of diagnostic delay in spondyloarthritis: insights from the ASAS-PerSpA international study
Rheumatology (Oxford, England) · 2026 · Journal Article
Aoun M, Gamal SM, Hmamouchi I, Lopez-Medina C, et al.
📚 2 cit.🔬→🩺 Translationnel - Impact of Social Factors on Visual Analog Scale Pain in Patients With Spondyloarthritis: A Propensity Score Matching Analysis
Arthritis care & research · 2026 · Journal Article
Calvo Pascual LÁ, Castro Corredor D, Collantes-Estévez E, López-Medina C
📚 1 cit. - From advanced imaging to molecular insights: the state of the art in omics for axial spondyloarthritis
Therapeutic advances in musculoskeletal disease · 2025 · Journal Article
Arias-de la Rosa I, Martín-Salazar JE, Cuesta-López L, López-Medina C C, et al.
- Clinical and molecular links between chronic systemic inflammation and structural damage in axial spondyloarthritis
Arthritis research & therapy · 2025 · Journal Article
Cuesta-López L, Arias-de la Rosa I, Ladehesa-Pineda ML, Puche-Larrubia MÁ, et al.
- Apremilast attenuates hepatic steatosis and metabolic dysfunction in a murine model of MASLD: Implications for patients with Psoriatic disease
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie · 2025 · Journal Article
Ruiz-Ponce M, Rodriguez-Cuenca S, Martin-Salazar JE, Pérez-Sánchez C, et al.
- Advancing Psoriatic Disease Knowledge: Highlights From the GRAPPA 2024 Trainee Symposium
The Journal of rheumatology · 2025 · Conference Proceedings
López-Medina C, Mulder M, Eder L, Husni ME
- Systemic sclerosis: bridging clinical and molecular insights: results from the PRECISESADS study
Journal of translational medicine · 2025 · Journal Article
Dans-Caballero S, Ortega-Castro R, López-Pedrera C, Escudero-Contreras A, et al.
- Disease phenotype and management of axial psoriatic arthritis in Japan compared with other regions, particularly other Asian countries: results of the ASAS-PerSpA study
BMC rheumatology · 2025 · Journal Article
Sawada H, Kishimoto M, Tada K, Deshpande GA, et al.
- Evaluation of spondyloarthritis-specific health utility based on ASAS health index (U-ASAS-HI) among the disease subtypes: an ancillary analysis from the ASAS-PerSpA study
RMD open · 2025 · Journal Article
Calixto OJ, Baraliakos X, Bautista-Molano W, Boonen A, et al.
- Uveitis in Longstanding Axial Spondyloarthritis and Its Association with Biologic Therapy Initiation: Data from the REGISPON-3 Cohort
Journal of clinical medicine · 2025 · Journal Article
Sánchez-León AM, Ladehesa-Pineda ML, Puche-Larrubia MÁ, Ábalos-Aguilera MC, et al.
- Seventeen-year reassessment of diagnostic transitions, biologic therapy initiation and mortality in spondyloarthritis: results from the REGISPON-3 study
RMD open · 2025 · Journal Article
Puche-Larrubia MÁ, Ladehesa-Pineda L, Ábalos-Aguilera MC, Ruiz-Vílchez D, et al.
📚 2 cit.🔬→🩺 Translationnel - Arthroscopic Repair Versus Conservative Treatment in Degenerative Cuff Tears: Midterm Results
Life (Basel, Switzerland) · 2025 · Journal Article
Camacho-Sanchez MR, Calzado-Alvarez I, Minarro JC, Dussan-Arango DM, et al.
📚 2 cit. - Evaluation of instruments assessing peripheral arthritis in spondyloarthritis: an analysis of the ASAS-PerSpA study
Annals of the rheumatic diseases · 2025 · Journal Article
Capelusnik D, Lopez-Medina C, van der Heijde D, Landewé R, et al.
📚 4 cit.🔬→🩺 Translationnel - Measurement properties of disease activity instruments in peripheral spondyloarthritis: a post-hoc analysis of the CRESPA trial
RMD open · 2025 · Journal Article
López-Medina C, Capelusnik D, Webers C, Van den Bosch F, et al.
📚 2 cit.🩺 Clinique - Adaptive immune responses to SARS-CoV-2 in DMARD-treated patients with chronic inflammatory rheumatisms
RMD open · 2025 · Journal Article
Beretta M, Martin E, Fogel O, López-Medina C, et al.
- Molecular insights into the relationship between sustained CRP elevation and endothelial dysfunction in axial spondyloarthritis
RMD open · 2025 · Journal Article
Cuesta-López L, Arias-de la Rosa I, Martín-Salazar JE, Barranco AM, et al.
📚 6 cit.🎯 RCR 2.33 - Variability of Psoriatic Arthritis Impact of Disease questionnaire (PsAID12) thresholds in psoriatic arthritis: data from the ReFlaP study
Rheumatology (Oxford, England) · 2025 · Journal Article
López-Medina C, Gorlier C, Orbai AM, Coates LC, et al.
📚 1 cit.🩺 Clinique - Translation and cross-cultural adaptation of the Coping with Rheumatic Stressors (CORS) into French language
Joint bone spine · 2025 · Letter
López-Medina C, Ramiro S, van Durme C, Ez-Zaitouni Z, et al.
- Global health in axial spondyloarthritis: thresholds for the Assessment of SpondyloArthritis international Society Health Index and the EuroQol score: analysis of the ASAS-PerSpA study
Scandinavian journal of rheumatology · 2025 · Journal Article
Drouet J, López-Medina C, Molto A, Granger B, et al.
- Do Obesity and Adipose Tissue Cytokines Influence the Response to Janus Kinase Inhibitors in Rheumatoid Arthritis?
Nutrients · 2025 · Journal Article
Novella-Navarro M, Van Den Rym A, López-Pedrera C, Martínez-Feito A, et al.
📚 3 cit.🔬→🩺 Translationnel - [Treatment of psoriatic arthritis]
La Revue du praticien · 2025 · Journal Article
LópezMedina C, Gossec L
- Performance analysis of a deep-learning algorithm to detect the presence of inflammation in MRI of sacroiliac joints in patients with axial spondyloarthritis
Annals of the rheumatic diseases · 2025 · Journal Article
Nicolaes J, Tselenti E, Aouad T, López-Medina C, et al.
📚 12 cit.🎯 RCR 5.62🩺 Clinique - Subclinical psoriatic arthritis and disease interception-where are we in 2024?
Rheumatology (Oxford, England) · 2025 · Journal Article
López-Medina C, McGonagle D, Gossec L
📚 13 cit.🎯 RCR 5.80
Épidémiologie & registres6
▼
Épidémiologie & registres6
▼- The impact of structural damage and muscle properties on spinal mobility in axial spondyloarthritis: A sensor-based analysis from the CASTRO registry
The spine journal : official journal of the North American Spine Society · 2026 · Journal Article
Moldovan DMM, Aranda-Valera IC, Ladehesa-Pineda L, Ábalos-Aguilera MDC, et al.
- Sex-based differences in bDMARD initiation and persistence in spondyloarthritis: a 17-year follow-up study from the REGISPON-3 registry
Rheumatology (Oxford, England) · 2026 · Journal Article
Moldovan DMM, Ladehesa-Pineda L, Puche-Larrubia MÁ, Ábalos-Aguilera MC, et al.
🩺 Clinique - Prevalence and impact of suspected fibromyalgia on disease outcomes and treatment in axial spondyloarthritis: 10-year follow-up data from the DESIR cohort
Annals of the rheumatic diseases · 2026 · Journal Article
López-Medina C, Chevret S, Lukas C, Moltó A, et al.
- The association of cervical and lumbar mobility with functional ability in axial spondyloarthritis: Insights from the CASTRO registry using Inertial Measurement Unit system
Seminars in arthritis and rheumatism · 2025 · Journal Article
Moldovan DMM, Aranda-Valera IC, Ladehesa-Pineda L, Ábalos-Aguilera MC, et al.
📚 1 cit. - Prevalence and incidence of uveitis in patients with spondyloarthritis: the impact of the biologics era. Data from the international ASAS-COMOSPA study
Rheumatology (Oxford, England) · 2025 · Journal Article
Maldonado-Ficco H, López-Medina C, Perez-Alamino R, Waimann CA, et al.
📚 6 cit.🎯 RCR 2.72 - Association Between Diagnostic Delay and Short-Term Outcomes in Patients with Radiographic Axial Spondyloarthritis: Results from the Regisponser-AS Registry
Journal of clinical medicine · 2025 · Journal Article
Ladehesa-Pineda ML, Ruiz-Vilchez D, Barranco AM, Puche-Larrubia MÁ, et al.
📚 3 cit.🔬→🩺 Translationnel
Spondyloarthrite3
▼
Spondyloarthrite3
▼- Sustained resolution of enthesitis and peripheral arthritis over 104 weeks with bimekizumab in axial spondyloarthritis
RMD open · 2025 · Clinical Trial, Phase III
Ramiro S, Poddubnyy D, Mease PJ, López-Medina C, et al.
📚 1 cit.🩺 Clinique - Ultrasonography for the assessment of enthesitis in psoriatic arthritis: systematic review with meta-analysis
Rheumatology (Oxford, England) · 2025 · Journal Article
Bibas N, Pignon C, Lopez-Medina C, Gandjbakhch F, et al.
📚 8 cit.🎯 RCR 3.74🔬→🩺 Translationnel - Clinical enthesitis in patient with psoriatic arthritis, a systematic literature review with metaanalysis
Joint bone spine · 2025 · Journal Article
Pignon C, Bibas N, Lopez-Medina C, Fautrel B, et al.
📚 4 cit.🔬→🩺 Translationnel
Anti-IL-172
▼
Anti-IL-172
▼- Circulating IL-17A accumulation reflects effective target blockade with secukinumab in spondyloarthritis
Frontiers in immunology · 2026 · Journal Article
Martínez-Moreno JM, Llamas-Urbano A, Romero-Zurita L, Hanaee Y, et al.
- One-year retention rate of ixekizumab in patients with psoriatic arthritis and axial spondyloarthritis: Real-world data from the BIOBADASER registry
Reumatologia clinica · 2025 · Journal Article
López-Medina C, Otero-Varela L, Sánchez-Alonso F, Jovaní V, et al.
📚 1 cit.🩺 Clinique
Génétique2
▼
Génétique2
▼- Clinical Expression of Radiographic Axial Spondyloarthritis and Its Association With HLA-B27 in European and Ibero-American Populations
The Journal of rheumatology · 2025 · Journal Article
Puche-Larrubia MÁ, Ladehesa-Pineda L, Font-Ugalde P, Burgos-Vargas R, et al.
🩺 Clinique - Clinical Expression of Radiographic Axial Spondyloarthritis and Its Association With HLA-B27 in European and Ibero-American Populations
The Journal of rheumatology · 2025 · Journal Article
Puche-Larrubia MÁ, Ladehesa-Pineda L, Font-Ugalde P, Burgos-Vargas R, et al.
Revue générale2
▼
Revue générale2
▼- Peripheral manifestations in spondyloarthritis: a systematic literature review on their assessment and the effect of biological/targeted synthetic DMARDs
Rheumatology (Oxford, England) · 2026 · Journal Article
Webers C, Ortolan A, Nikiphorou E, Sepriano A, et al.
- Patient Profiles in Randomized Controlled Trials Versus a Real-World Study in Psoriatic Arthritis: Scoping Review and Metaanalysis
The Journal of rheumatology · 2025 · Journal Article
Alle G, Lopez-Medina C, Siebert S, Lavie F, et al.
📚 4 cit.🔬→🩺 Translationnel
Anti-IL-231
▼
Anti-IL-231
▼- Multi-domain effectiveness of guselkumab evaluated via composite indices through 1 year in patients with PsA and inadequate response to TNFi: post hoc analysis of COSMOS
Rheumatology (Oxford, England) · 2025 · Journal Article
Gossec L, Baraliakos X, Aletaha D, Sharaf M, et al.
📚 2 cit.🩺 Clinique
Anti-TNF1
▼
Anti-TNF1
▼- Inflammatory activity levels on patients with anti-TNF therapy: most important factors and a decision tree model based on REGISPONSER and RESPONDIA registries
Therapeutic advances in musculoskeletal disease · 2025 · Journal Article
Castro Corredor D, Calvo Pascual LÁ, Collantes-Estévez E, López-Medina C
📚 2 cit.
Biomarqueurs / Auto-Ac1
▼
Biomarqueurs / Auto-Ac1
▼- Impact of ACPA and RF titers and their reduction on therapeutic response after one year in rheumatoid arthritis patients
ARP rheumatology · 2025 · Journal Article
Garcia-Salinas R, Perez R, Ruta S, Arguello J, et al.
Économie santé1
▼
Économie santé1
▼- Obesity and its associations with clinical manifestations and disease burden of patients with spondyloarthritis: An ancillary study from the ASAS-PerSpA project
Seminars in arthritis and rheumatism · 2026 · Journal Article
Duruöz MT, Acer Kasman S, Gezer HH, López-Medina C, et al.
Essai clinique1
▼
Essai clinique1
▼- Patient Profiles in Randomized Controlled Trials Versus a Real-World Study in Psoriatic Arthritis: Scoping Review and Metaanalysis
The Journal of rheumatology · 2025 · Journal Article
Alle G, Lopez-Medina C, Siebert S, Lavie F, et al.
📚 4 cit.🔬→🩺 Translationnel
Ostéoporose1
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Ostéoporose1
▼- Bisphosphonate drug holidays in osteoporosis according to fracture risk profile
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2025 · Journal Article
Salmoral A, Peris P, López Medina C, Flórez H, et al.
📚 2 cit.🩺 Clinique
Pharmacovigilance1
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Pharmacovigilance1
▼- Impact of a clinical pharmacist consultation on enhancing knowledge and safety skills in patients with chronic inflammatory arthritis treated with bDMARDs
Clinical and experimental rheumatology · 2025 · Journal Article
Bottois C, Lopez Medina C, Dumas S, Hubert J, et al.
Recommandations1
▼
Recommandations1
▼- Diagnosis and therapeutic management of psoriatic arthritis: summary of 2024 update of the Spanish clinical practice guideline (ESPOGUIA)
Therapeutic advances in musculoskeletal disease · 2026 · Journal Article
Ramírez J, López-Medina C, Montilla C, Moreno M, et al.
Rhumatisme psoriasique1
▼
Rhumatisme psoriasique1
▼- Multi-domain effectiveness of guselkumab evaluated via composite indices through 1 year in patients with PsA and inadequate response to TNFi: post hoc analysis of COSMOS
Rheumatology (Oxford, England) · 2025 · Journal Article
Gossec L, Baraliakos X, Aletaha D, Sharaf M, et al.
📚 2 cit.🩺 Clinique
Tendinopathies & SCC1
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Tendinopathies & SCC1
▼- Comparison of Ligament Z-Plasty and Conventional Surgery for the Treatment of Carpal Tunnel Syndrome: A Randomized Clinical Trial
Plastic and reconstructive surgery · 2025 · Journal Article
Calzado-Alvarez I, Camacho-Sanchez MR, Carpintero-Lluch R, Muñoz-Luna F, et al.
📚 2 cit.🩺 Clinique
Vraie vie / RWE1
▼
Vraie vie / RWE1
▼- Patient Profiles in Randomized Controlled Trials Versus a Real-World Study in Psoriatic Arthritis: Scoping Review and Metaanalysis
The Journal of rheumatology · 2025 · Journal Article
Alle G, Lopez-Medina C, Siebert S, Lavie F, et al.
📚 4 cit.🔬→🩺 Translationnel
Datasets & protocoles partagés
Enhanced NETosis generation in radiographic axial spondyloarthritis: utility as biomarker for disease activity and anti-TNF-α therapy effectiveness
Collection2020figshareAbstract Background Radiographic axial spondyloarthritis (r-axSpA) is a chronic inflammatory form of arthritis in which tumor necrosis factor (TNF)-α, a potent inducer of inflammatory response and a key regulator of inna
Enhanced NETosis generation in radiographic axial spondyloarthritis: utility as biomarker for disease activity and anti-TNF-α therapy effectiveness
Collection2020figshareAbstract Background Radiographic axial spondyloarthritis (r-axSpA) is a chronic inflammatory form of arthritis in which tumor necrosis factor (TNF)-α, a potent inducer of inflammatory response and a key regulator of inna
Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).
