Docteur ERICK LEGRAND
Diplômes
🎓 DES & spécialité ordinale
- DES Rhumatologie
- Rhumatologie (SM)
🎓 Diplômes
- DE Docteur en médecine
Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.
Direction de thèses
🎓 1 thèse dirigéeSource theses.fr — signal de direction d'équipe / statut PU-PH (à confirmer via le site universitaire).
Activité de recherche & publications
Source : bases de données publiques (OpenAlex, PubMed).
h-index
35
h articles cités ≥ h fois chacun. Un h de 35 = 35 publications avec 35+ citations.
Citations
5 059
Publications
194
i10-index
73
Thématiques principales
- Bone health and osteoporosis research ×73
- Bone health and treatments ×44
- Bone Metabolism and Diseases ×31
- Vitamin D Research Studies ×24
- Musculoskeletal pain and rehabilitation ×17
Affiliations FR : Inserm · Université Nantes Angers Le Mans · Centre Hospitalier Universitaire d'Angers
Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.
Bibliographie
The cost of severe osteoporotic fractures
2024ArticleRevue du Rhumatisme
Development of a First‐in‐Class Unimolecular Dual GIP / GLP ‐2 Analogue, GL ‐0001, for the Treatment of Bone Fragility
2023ArticleJournal of Bone and Mineral Research
[Gly²]-GLP-2, But Not Glucagon or [D-Ala²]-GLP-1, Controls Collagen Crosslinking in Murine Osteoblast Cultures
2021ArticleFrontiers in Endocrinology
COVID-19 outcomes in patients with inflammatory rheumatic and musculoskeletal diseases treated with rituximab: a cohort study
2021ArticleThe Lancet Rheumatology
Osteoporosis in older adults
2021ArticleJoint Bone Spine
Recommandations françaises de la prise en charge et du traitement de l’ostéoporose masculine
2021ArticleRevue du Rhumatisme
Severity of COVID-19 and survival in patients with rheumatic and inflammatory diseases: data from the French RMD COVID-19 cohort of 694 patients
2020ArticleAnnals of the Rheumatic Diseases
Vitamin D Supplementation Associated to Better Survival in Hospitalized Frail Elderly COVID-19 Patients: The GERIA-COVID Quasi-Experimental Study
2020ArticleNutrients
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
Livres & ouvrages
Source : Google Books — filtre catégories médicales/santé/sciences.
Lieu de consultation
CHU ANGERS SITE LARREY
4 Rue LARREY, 49933 Angers
Tarifs & secteur de conventionnement
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Prendre rendez-vous & contact
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Articles de presse (6)
Source : Google News (recherche par nom complet — homonymes possibles, vérifier le contenu).
- Comment soigner le mal de dos - Les traitements physiques - Conseils - Que Choisir
📰 Que Choisir · 21/08/2025
<a href="https://news.google.com/rss/articles/CBMiogFBVV95cUxOOGpmUmNMQ2U4ZjFJZnE5Mk1OdjgxSVhHUXUxZGYtbHNCa3ZaSHBoc0ZGTXVleEREVkp1UTR5UEdrRV8wVk5FMzVVcUZYX1FTQ2hWU1QwSlpyVlJHNnlNYlBLMXdzVUJOVkh0dmNYWDJFY2YzZkxCaF8xMFFRbHg0UEl3dE5xWU9pTGJvMTk5NmliZG5iRGt1ZlR0cm9LN3AzMVE?oc=5" target="_blank">Comment
- Angers. Mardis de la santé sur l’ostéoporose : les fractures qui doivent alerter - Ouest-France
📰 Ouest-France · 02/02/2020
<a href="https://news.google.com/rss/articles/CBMiggJBVV95cUxNWWpsRE9ZME9WOGhWRUh4RmVlVW53ejhqRjNqSmR5WUM1T1hJalBhRHJhRERPNlBlZ3ZzQ1J2dk5uMEZYOEFzem9LMWw3NVp4ZWg3SUo0bVFhMlRoOFBpM1gyeS00MzU5ajRIeUE3NjV1TEZwVHRfUzJjT2IycXRXcnR6YjBNQUdTYTMwenVDak5HQTEyM3VvVTBXLWdsRlltSkdiVG1ZLUkwdjlKdE94MURoQXhlMEw4Z0
- ENQUÊTE. Que fait le CHU d’Angers avec l’argent des labos pharmaceutiques ? - Ouest-France
📰 Ouest-France · 10/01/2020
<a href="https://news.google.com/rss/articles/CBMivwFBVV95cUxONmF5dnVUbGxRX0VxVlBhVlFldnRHUTh1V19QWDNrc0JfVUg4YzdKTjRGeUM5MVJBVjFDU3FKNzRLdnFRYlZCdklvaUNrTlBiWjd3VVVnbzlvdnF6N2V3M3ZCLWJGejFkQlBBdUN1TElmeDc1bmltTkt2STZtM2Nqam5hYUlUeXE0XzV3Z1QxWHRRN3VRQ2QxYzZBV3dEeHRhTk5tVXpZSVF6MlJWLXFHNGh2WEtBY29IRn
- Angers. Décès de Jean-Claude Antonini : l'hommage du CHU - Ouest-France
📰 Ouest-France · 08/02/2019
<a href="https://news.google.com/rss/articles/CBMi4AFBVV95cUxPTnR0NU83NTVPbEJuLVBLWGpXY2ZvMnc3azJiTlJ6dXFIekQ0bTVRQTNERVpCcGpsQ1ZoR0lISDg2QXBvUVVBbUFGcGQ5aWgwOTFSU0JOd05DZlptb3MyUms1d0dZdmZxeXhXeGU5Y203SzViX043Y19JejZlbHJnX3NMNHZ0WE40Y3F2VEdZY2Q5UzVZang4cjE0MC03Z2JCVlZHalJlMFk4TFB2b0k5MFlFcHNpbWJUVU
- Angers. Les clés pour vieillir en bonne santé - Maville Angers
📰 Maville Angers · 08/10/2018
<a href="https://news.google.com/rss/articles/CBMirgFBVV95cUxQQnpIWlNIWU04UUJDdjF5c1ZGVUlXZGNjUnh3RWxuUXpRdWhjVnJDc1B3ZG5XUG42cGo4U3pxWktVT0dpQVhSeTBoQ3dTMm5CSFRBQWtCellPRWh2UlBla3RMdjF3dFk1cWd4eWlKTXd4bWlFZnNYYlVYTWJod3c4bTBOa0JTVGVEMGxodFBiY2xhV0kycm9qdWt6M2pvSnREbGNsa3lvc25PaHl3b1E?oc=5" target="
- Angers. Le mal de dos au menu de ce Mardi de la santé à l'Institut municipal - Maville Angers
📰 Maville Angers · 10/10/2016
<a href="https://news.google.com/rss/articles/CBMi1wFBVV95cUxQRGtfaEcxeG9ZVmUxcE1HWl83M1BCQ21uaGZYWUhtbUx2TUEtMWxwd1piN2JraEtpMV9kdHRsbnM0QzhJQTVtZ1MybHoyYXpHRU10ajdvVU1iRTVmdXg5VWp1QTUyVTdWeEhjX3ZyTm5Fa2hiaXRiOGc4ZExJdWpVN1hXTG4zcjFhZ2NsN3I4NE1IeEhBYXZzWl9XdDRGTEFSUnVMWlRCckZKYnV2d3FzRm0xbmdGc3RITn
Top publications · les plus citées
- 1Psychosocial risk factors for chronic low back pain in primary care--a systematic review
Family practice · 2011
- 2Vitamin D Supplementation Associated to Better Survival in Hospitalized Frail Elderly COVID-19 Patients: The GERIA-COVID Quasi-Experimental Study
Nutrients · 2020
Lire l'abstract Crossref ↓
Background. The objective of this quasi-experimental study was to determine whether bolus vitamin D supplementation taken either regularly over the preceding year or after the diagnosis of COVID-19 was effective in improving survival among hospitalized frail elderly COVID-19 patients. Methods. Seventy-seven patients consecutively hospitalized for COVID-19 in a geriatric unit were included. Intervention groups were participants regularly supplemented with vitamin D over the preceding year (Group 1), and those supplemented with vitamin D after COVID-19 diagnosis (Group 2). The comparator group involved participants having received no vitamin D supplements (Group 3). Outcomes were 14-day mortality and highest (worst) score on the ordinal scale for clinical improvement (OSCI) measured during COVID-19 acute phase. Potential confounders were age, gender, functional abilities, undernutrition, cancer, hypertension, cardiomyopathy, glycated hemoglobin, number of acute health issues at admission, hospital use of antibiotics, corticosteroids, and pharmacological treatments of respiratory disorders. Results. The three groups (n = 77; mean ± SD, 88 ± 5 years; 49% women) were similar at baseline (except for woman proportion, p = 0.02), as were the treatments used for COVID-19. In Group 1 (n = 29), 93.1% of COVID-19 participants survived at day 14, compared to 81.2% survivors in Group 2 (n = 16) (p = 0.33) and 68.7% survivors in Group 3 (n = 32) (p = 0.02). While considering Group 3 as reference (hazard ratio (HR) = 1), the fully-adjusted HR for 14-day mortality was HR = 0.07 (p = 0.017) for Group 1 and HR = 0.37 (p = 0.28) for Group 2. Group 1 had longer survival time than Group 3 (log-rank p = 0.015), although there was no difference between Groups 2 and 3 (log-rank p = 0.32). Group 1, but not Group 2 (p = 0.40), was associated with lower risk of OSCI score ≥5 compared to Group 3 (odds ratio = 0.08, p = 0.03). Conclusions. Regular bolus vitamin D supplementation was associated with less severe COVID-19 and better survival in frail elderly.
- 32018 update of French recommendations on the management of postmenopausal osteoporosis
Joint bone spine · 2018
Publications scientifiques (50) — classées par pathologie
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Transversal35
▼
Transversal35
▼- Development of a First-in-Class Unimolecular Dual GIP/GLP-2 Analogue, GL-0001, for the Treatment of Bone Fragility
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2023 · Journal Article
Gobron B, Couchot M, Irwin N, Legrand E, et al.
📚 20 cit.🎯 RCR 3.31 - Osteoporosis in older adults
Joint bone spine · 2021 · Journal Article
Bouvard B, Annweiler C, Legrand E
📚 57 cit.🎯 RCR 5.16🔬→🩺 Translationnel - [Gly²]-GLP-2, But Not Glucagon or [D-Ala²]-GLP-1, Controls Collagen Crosslinking in Murine Osteoblast Cultures
Frontiers in endocrinology · 2021 · Journal Article
Mieczkowska A, Bouvard B, Legrand E, Mabilleau G
📚 9 cit. - Enteroendocrine K Cells Exert Complementary Effects to Control Bone Quality and Mass in Mice
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2020 · Journal Article
Gobron B, Bouvard B, Vyavahare S, Blom LV, et al.
📚 16 cit. - GLP-2 administration in ovariectomized mice enhances collagen maturity but did not improve bone strength
Bone reports · 2020 · Journal Article
Gobron B, Bouvard B, Legrand E, Chappard D, et al.
📚 13 cit. - Bone lesions in systemic mastocytosis: Bone histomorphometry and histopathological mechanisms
Morphologie : bulletin de l'Association des anatomistes · 2020 · Journal Article
Bouvard B, Pascaretti-Grizon F, Legrand E, Lavigne C, et al.
📚 10 cit. - Vitamin D Supplementation in France in patients with or at risk for osteoporosis: Recent data and new practices
Joint bone spine · 2020 · Journal Article
Souberbielle JC, Cormier C, Cavalier E, Breuil V, et al.
📚 11 cit.🔬→🩺 Translationnel - The prognosis of streptococcal prosthetic bone and joint infections depends on surgical management-A multicenter retrospective study
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2019 · Journal Article
Mahieu R, Dubée V, Seegers V, Lemarié C, et al.
📚 31 cit.🎯 RCR 2.24 - Osteoporosis treatment and 10 years' oestrogen receptor+ breast cancer outcome in postmenopausal women treated with aromatase inhibitors
European journal of cancer (Oxford, England : 1990) · 2018 · Journal Article
Bouvard B, Chatelais J, Soulié P, Hoppé E, et al.
📚 11 cit.🔬→🩺 Translationnel - 2018 update of French recommendations on the management of postmenopausal osteoporosis
Joint bone spine · 2018 · Journal Article
Briot K, Roux C, Thomas T, Blain H, et al.
📚 88 cit.🎯 RCR 4.81🔬→🩺 Translationnel - Osteoporosis in Stickler syndrome. A new family case with bone histology study
Morphologie : bulletin de l'Association des anatomistes · 2017 · Case Reports
Insalaco P, Legrand E, Bouvard B, Audran M
📚 2 cit. - Low-trauma fractures without osteoporosis
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2017 · Journal Article
Lespessailles E, Cortet B, Legrand E, Guggenbuhl P, et al.
📚 43 cit.🎯 RCR 2.34🔬→🩺 Translationnel - French law: what about a reasoned reimbursement of serum vitamin D assays?
Geriatrie et psychologie neuropsychiatrie du vieillissement · 2016 · Journal Article
Souberbielle JC, Benhamou CL, Cortet B, Rousière M, et al.
📚 7 cit. - Reimbursment of the serum CTX assay in France: the clinical biology nomenclature is incoherent
Annales de biologie clinique · 2016 · Editorial
Souberbielle JC, Bendavid S, Blain H, Bousson V, et al.
- Trabecular Bone Score: Where are we now?
Joint bone spine · 2015 · Journal Article
Bousson V, Bergot C, Sutter B, Thomas T, et al.
📚 37 cit.🎯 RCR 2.01🔬→🩺 Translationnel - Factors associated with an increased risk of vertebral fracture in monoclonal gammopathies of undetermined significance
Blood cancer journal · 2015 · Journal Article
Piot JM, Royer M, Schmidt-Tanguy A, Hoppé E, et al.
📚 18 cit.🔬→🩺 Translationnel - [Weakening osteopathies, chronic kidney disease, malabsorption, biological anomalies of calium/phosphorus metabolism: appropriate indications for a reasoned reimbursment of serum vitamin D measurement]
Annales de biologie clinique · 2014 · Editorial
Souberbielle JC, Benhamou CL, Cortet B, Rousière M, et al.
📚 3 cit. - [HAS report on vitamin D measurement: don't go from an extreme situation to another as extreme situation]
Presse medicale (Paris, France : 1983) · 2014 · Editorial
Souberbielle JC, Benhamou CL, Cortet B, Rousière M, et al.
📚 12 cit. - Difficulties in the diagnosis of vertebral fracture in men: agreement between doctors
Joint bone spine · 2014 · Journal Article
Fechtenbaum J, Briot K, Paternotte S, Audran M, et al.
📚 18 cit. - Is androgen therapy indicated in men with osteoporosis?
Joint bone spine · 2013 · Journal Article
Hoppé E, Bouvard B, Royer M, Chappard D, et al.
📚 8 cit. - Glucocorticoids reduce alveolar and trabecular bone in mice
Joint bone spine · 2013 · Journal Article
Bouvard B, Gallois Y, Legrand E, Audran M, et al.
📚 24 cit.🎯 RCR 1.02 - Stress fractures in 2011: practical approach
Joint bone spine · 2012 · Journal Article
Royer M, Thomas T, Cesini J, Legrand E
📚 9 cit. - [Osteoporosis in men]
La Revue du praticien · 2012 · English Abstract
Legrand E, Hoppé E, Bouvard B, Audran M
- Is transiliac bone biopsy a painful procedure?
Clinical nephrology · 2012 · Journal Article
Audran M, Maury E, Bouvard B, Legrand E, et al.
📚 12 cit. - Validation of the adherence evaluation of osteoporosis treatment (ADEOS) questionnaire for osteoporotic post-menopausal women
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2012 · Journal Article
Breuil V, Cortet B, Cotté FE, Arnould B, et al.
📚 25 cit.🎯 RCR 1.22🔬→🩺 Translationnel - Management of male osteoporosis: lessons for clinical practice
Joint bone spine · 2011 · Editorial
Cortet B, Biver E, Borg S, Chopin F, et al.
📚 2 cit. - Profile of French community-dwelling older adults supplemented with vitamin D: findings and lessons
Advances in therapy · 2011 · Journal Article
Fantino B, Beauchet O, Savignat S, Bouvard B, et al.
📚 8 cit.🔬→🩺 Translationnel - Male osteoporosis: do sex steroids really benefit bone health in men?
Joint bone spine · 2011 · Editorial
Hoppé E, Morel G, Biver E, Borg S, et al.
📚 7 cit.🔬→🩺 Translationnel - Extraskeletal effects of vitamin D: facts, uncertainties, and controversies
Joint bone spine · 2011 · Journal Article
Bouvard B, Annweiler C, Sallé A, Beauchet O, et al.
📚 29 cit.🎯 RCR 1.02🔬→🩺 Translationnel - Computed microtomography of bone specimens for rapid analysis of bone changes associated with malignancy
Anatomical record (Hoboken, N.J. : 2007) · 2010 · Journal Article
Chappard D, Libouban H, Legrand E, Ifrah N, et al.
📚 16 cit. - Sex hormone-binding globulin in osteoporosis
Joint bone spine · 2010 · Journal Article
Hoppé E, Bouvard B, Royer M, Audran M, et al.
📚 55 cit.🎯 RCR 1.74🔬→🩺 Translationnel - The cathepsin K inhibitor AAE581 induces morphological changes in osteoclasts of treated patients
Microscopy research and technique · 2010 · Clinical Trial, Phase II
Chappard D, Libouban H, Mindeholm L, Baslé MF, et al.
📚 16 cit.🩺 Clinique - Severity of osteoporosis: what is the impact of co-morbidities?
Joint bone spine · 2010 · Journal Article
David C, Confavreux CB, Mehsen N, Paccou J, et al.
📚 27 cit.🔬→🩺 Translationnel - Severe osteoporosis: diagnosis and follow-up. Lessons for clinical practice
Joint bone spine · 2010 · Journal Article
Roux C, Confavreux CB, Cortet B, David C, et al.
📚 8 cit. - Monoclonal gammopathy of undetermined significance, multiple myeloma, and osteoporosis
Joint bone spine · 2010 · Journal Article
Bouvard B, Royer M, Chappard D, Audran M, et al.
📚 19 cit.
Épidémiologie & registres3
▼
Épidémiologie & registres3
▼- High Incidence of Amoxicillin-Induced Crystal Nephropathy in Patients Receiving High Dose of Intravenous Amoxicillin
Journal of clinical medicine · 2020 · Journal Article
Garnier AS, Dellamaggiore J, Brilland B, Lagarce L, et al.
📚 18 cit.🎯 RCR 1.40🔬→🩺 Translationnel - Prevalence of shoulder calcification in pseudoxanthoma elasticum patients
Joint bone spine · 2018 · Letter
Hoppé E, Etienne M, Legrand E, Rutsch F, et al.
📚 3 cit.🔬→🩺 Translationnel - Fracture incidence after 3 years of aromatase inhibitor therapy
Annals of oncology : official journal of the European Society for Medical Oncology · 2014 · Journal Article
Bouvard B, Soulié P, Hoppé E, Georgin-Mege M, et al.
📚 29 cit.🔬→🩺 Translationnel
Gériatrie3
▼
Gériatrie3
▼- Vitamin D Supplementation Associated to Better Survival in Hospitalized Frail Elderly COVID-19 Patients: The GERIA-COVID Quasi-Experimental Study
Nutrients · 2020 · Journal Article
Annweiler G, Corvaisier M, Gautier J, Dubée V, et al.
📚 186 cit.🎯 RCR 11.23🔬→🩺 Translationnel - High parathyroid hormone, but not low vitamin D concentrations, expose elderly inpatients to hypertension
Geriatrics & gerontology international · 2013 · Comparative Study
Mateus-Hamdan L, Beauchet O, Bouvard B, Legrand E, et al.
📚 16 cit.🔬→🩺 Translationnel - Serum vitamin D concentration and short-term mortality among geriatric inpatients in acute care settings
Advances in therapy · 2010 · Journal Article
Annweiler C, Pochic S, Fantino B, Legrand E, et al.
📚 23 cit.🔬→🩺 Translationnel
Corticothérapie2
▼
Corticothérapie2
▼- 2014 update of recommendations on the prevention and treatment of glucocorticoid-induced osteoporosis
Joint bone spine · 2014 · Journal Article
Briot K, Cortet B, Roux C, Fardet L, et al.
📚 73 cit.🎯 RCR 2.86🩺 Clinique - Management of glucocorticoid-induced osteoporosis: lessons for clinical practice
Joint bone spine · 2011 · Editorial
Roux C, Rajzbaum G, Morel G, Legrand E, et al.
📚 2 cit.
Lombalgie2
▼
Lombalgie2
▼- Psychosocial risk factors for chronic low back pain in primary care--a systematic review
Family practice · 2011 · Journal Article
Ramond A, Bouton C, Richard I, Roquelaure Y, et al.
📚 258 cit.🎯 RCR 12.55🔬→🩺 Translationnel - Multidisciplinary intensive functional restoration versus outpatient active physiotherapy in chronic low back pain: a randomized controlled trial
Spine · 2011 · Journal Article
Roche-Leboucher G, Petit-Lemanac'h A, Bontoux L, Dubus-Bausière V, et al.
📚 53 cit.🎯 RCR 2.68🩺 Clinique
Anti-TNF1
▼
Anti-TNF1
▼- [Severe hypercalcemia revealing sarcoidosis precipitated by etanercept]
Revue des maladies respiratoires · 2014 · Case Reports
Watrin A, Royer M, Legrand E, Gagnadoux F
📚 7 cit.
Essai clinique1
▼
Essai clinique1
▼- Caregiver placebo effects
Journal of the American Veterinary Medical Association · 2013 · Letter
LeGrand EK
Qualité de vie / PROMs1
▼
Qualité de vie / PROMs1
▼- Accuracy of patient-reported height loss and risk factors for height loss among postmenopausal women
CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2010 · Journal Article
Briot K, Legrand E, Pouchain D, Monnier S, et al.
📚 33 cit.🎯 RCR 1.20🔬→🩺 Translationnel
Revue générale1
▼
Revue générale1
▼- Vitamin D in adults: update on testing and supplementation
Geriatrie et psychologie neuropsychiatrie du vieillissement · 2018 · Journal Article
Annweiler C, Legrand E, Souberbielle JC
📚 13 cit.🔬→🩺 Translationnel
Vraie vie / RWE1
▼
Vraie vie / RWE1
▼- Cost-effectiveness model of using zoledronic acid once a year versus current treatment strategies in postmenopausal osteoporosis
Joint bone spine · 2010 · Comparative Study
Fardellone P, Cortet B, Legrand E, Bresse X, et al.
📚 12 cit.
