📇 Rhumatologue · ST NAZAIRE · (44) · Libéral
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2 raisons identifiées
Praticien-chercheur
8 articles scientifiques publiés — formation continue solide
Délais de RDV courts dans la région
129.9 rhumatos / 100 000 hab. — département bien doté
✨ Génération du profil synthétique IA en cours…
CABINET DU DR BENOIT LEGRAND
SOS MEDECINS 28 BOULEVARD DE L UNIVERSITE, 44600 ST NAZAIRE
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
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Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Critical care (London, England) · 2016
Critical care medicine · 2020
Objectives: Cancer affects up to 20% of critically ill patients, and sepsis is one of the leading reasons for ICU admission in this setting. Early signals suggested that survival might be increasing in this population. However, confirmation studies have been lacking. The goal of this study was to assess trends in survival rates over time in cancer patients admitted to the ICU for sepsis or septic shock over the last 2 decades. Data Source: Seven European ICUs. Study Selection: A hierarchical model taking into account the year of admission and the source dataset as random variables was used to identify risk factors for day 30 mortality. Data Extraction: Data from cancer patients admitted to ICUs for sepsis or septic shock were extracted from the Groupe de Recherche Respiratoire en Réanimation Onco-Hématologique database (1994–2015). Data Synthesis: Overall, 2,062 patients (62% men, median [interquartile range] age 59 yr [48–67 yr]) were included in the study. Underlying malignancies were solid tumors (n = 362; 17.6%) or hematologic malignancies (n = 1,700; 82.4%), including acute leukemia (n = 591; 28.7%), non-Hodgkin lymphoma (n = 461; 22.3%), and myeloma (n = 244; 11.8%). Two-hundred fifty patients (12%) underwent allogeneic hematopoietic stem cell transplantation and 640 (31.0%) were neutropenic at ICU admission. Day 30 mortality was 39.9% (823 deaths). The year of ICU admission was associated with significant decrease in day 30 mortality over time (odds ratio, 0.96; 95% CI, 0.93–0.98; p = 0.001). Mechanical ventilation (odds ratio, 3.25; 95% CI, 2.52–4.19; p < 0.01) and vasopressors use (odds ratio, 1.42; 95% CI, 1.10–1.83; p < 0.01) were independently associated with day 30 mortality, whereas underlying malignancy, allogeneic hematopoietic stem cell transplantation, and neutropenia were not. Conclusions: Survival in critically ill oncology and hematology patients with sepsis improved significantly over time. As outcomes improve, clinicians should consider updating admission policies and goals of care in this population.
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Critical care medicine · 2020 · Journal Article
Lemiale V, Pons S, Mirouse A, Tudesq JJ, et al.
Critical care (London, England) · 2016 · Published Erratum
Author et al, Bateman RM, Sharpe MD, Jagger JE, et al.
Critical care (London, England) · 2016 · Conference Proceedings
Bateman RM, Sharpe MD, Jagger JE, Ellis CG, et al.
Open forum infectious diseases · 2015 · Journal Article
Benoit A, Beran J, Devaster JM, Esen M, et al.
Kidney international · 2018 · Journal Article
Ashton EJ, Legrand A, Benoit V, Roncelin I, et al.
Annals of intensive care · 2016 · Journal Article
Schnell D, Azoulay E, Benoit D, Clouzeau B, et al.
Diabetes & metabolism · 2008 · Journal Article
Riveline JP, Jollois FX, Messaoudi N, Franc S, et al.
Expert review of clinical pharmacology · 2013 · Journal Article
Dewe W, Benoit A, Legrand C