Docteur HUBERT LATHELIZE

Bibliographie

• Chronic renoprotective effect of pulsatile perfusion machine RM3 and IGL-1 solution in a preclinical kidney transplantation model

  2012

  ArticleJournal of Translational Medicine

• A therapy to make borderline grafts suitable: curcumin supplementation optimises function recovery and outcome

  2011

  Congrès15. Congress of the ESOT

• Curcumin treatment during preservation improves long term graft outcome

  2010

  CongrèsXXIIIth International Congress of the Transplantation Society (TTS 2010 Congress)

• A Way to Better Grafts: Curcumin Supplementation Improves Graft Outcome

  2010

  Congrès2010 American Transplant Congress

Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).

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Top publications · les plus citées

• 1

  Chronic renoprotective effect of pulsatile perfusion machine RM3 and IGL-1 solution in a preclinical kidney transplantation model

  Journal of translational medicine · 2012

  📚 26 citations🔓 Open Access📄 PDF gratuit ↗

  Lire l'abstract Crossref ↓

  Abstract Background Machine perfusion (MP) of kidney graft provides benefits against preservation injury, however decreased graft quality requires optimization of the method. We examined the chronic benefits of MP on kidney grafts and the potential improvements provided by IGL-1 solution. Method We used an established autotransplantation pig kidney model to study the effects of MP against the deleterious effects of warm ischemia (WI: 60 minutes) followed by 22 hours of cold ischemia in MP or static cold storage (CS) followed by autotransplantation. MPS and IGL-1 solutions were compared. Results Animal survival was higher in MPS-MP and both IGL groups. Creatinine measurement did not discriminate between the groups, however MPS-MP and both IGL groups showed decreased proteinuria. Chronic fibrosis level was equivalent between the groups. RTqPCR and immunohistofluorescent evaluation showed that MP and IGL-1 provided some protection against epithelial to mesenchymal transition and chronic lesions. IGL-1 was protective with both MP and CS, particularly against chronic inflammation, with only small differences between the groups. Conclusion IGL-1 used in either machine or static preservation offers similar levels of protection than standard MP. The compatibility of IGL-1 with both machine perfusion and static storage could represent an advantage for clinical teams when choosing the correct solution to use for multi-organ collection. The path towards improving machine perfusion, and organ quality, may involve the optimization of the solution and the correct use of colloids.

• 2

  Follow-up of aortic stent grafts: comparison of the volumetric analysis of the aneurysm sac by ultrasound and CT

  Annals of vascular surgery · 2014

  📚 16 citations
• 3

  Leiomyosarcoma of the Great Saphenous Vein: Case Report and Literature Review

  Annals of vascular surgery · 2019

  📚 10 citations

Publications scientifiques (3) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

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