Docteur Marc LABROUSSE

Thèses universitaires

• Le contenu de l'angle ponto-cérébelleux : artères et mouvements : morphogenèse, anatomie statique et dynamique

  2011

  Cerebello-pontine angle content : Motions and arteries : Morphogenesis, static and dynamic anatomy

  Sciences de la Vie et de la Santé🎓 Nancy 1

  Direction : Marc Braun

Source : catalogue national des thèses theses.fr (ABES). Ne couvre que les doctorats / HDR — les thèses d'exercice (DES) sont archivées dans les SCD universitaires.

• Peut-on décrire une segmentation pancréatique?

  2019

  Doctorant·e : Yohann Renard

  Sciences de la vie et de la sante🎓 Université de Lorraine

Source theses.fr — signal de direction d'équipe / statut PU-PH (à confirmer via le site universitaire).

Publications académiques en France

Articles déposés en accès libre sur l'archive ouverte des universités françaises (HAL) — gage d'activité de recherche en France.

• Brain exposure to SARS-CoV-2 virions perturbs synaptic homeostasis

  2024

  ArticleNature Microbiology

• Carcinomas of the external auditory canal: Management and results: A multicenter REFCOR propensity score matching study

  2024

  ArticleEuropean Journal of Cancer

• Intra-parotid facial nerve path by MRI tractography: radio-clinical comparison in parotid tumors

  2023

  ArticleEuropean Archives of Oto-Rhino-Laryngology

• Assessment of peak inspiratory flow in the management of acute inspiratory dyspnoea

  2021

  ArticleEuropean Archives of Oto-Rhino-Laryngology

• Efficacy and Complications of Microsurgical Neurovascular Decompression in 55 Patients With Hemifacial Spasm

  2020

  ArticleArchives of Otolaryngology Head and Neck Surgery

• Predictive Value of Early Post-Treatment Diffusion-Weighted MRI for Recurrence or Tumor Progression of Head and Neck Squamous Cell Carcinoma Treated with Chemo-Radiotherapy

  2020

  ArticleCancers

• Exploration of peripancreatic lymphatic pathways in a live porcine model

  2019

  ArticleAnnals of Anatomy

• A radio-anatomical correlation study of the cisterna chyli

  2018

  ArticleJournal of Anatomy

Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).

Lieu de consultation

• HOPITAL PURPAN CHU TOULOUSE

  BAT PIERRE PAUL RIQUET — Place DU DR BAYLAC, 31059 Toulouse

  ☎ 0561772233Hospitalier🏥 Centre CHU ↗🏥 Voir cet établissement

Tarifs & secteur de conventionnement

Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).

Prendre rendez-vous & contact

Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Vidéos & interventions (6)

Source YouTube · recherche par nom (homonymes possibles).

• 6:56

  On vous répond : l'apnée du sommeil

  France 3 Grand Est · 688 vues

• 2:00

  SOS médecin 26 mn TF1 réalisation Jean Marc Labrousse

  KEYWESTPRODUCTION · 7 k vues

• 1:43

  Brigade accident 26 mn TF1 réalisation Jean Marc Labrousse

  KEYWESTPRODUCTION · 9 k vues

• 1:48

  Extrait SAMU pédiatrique 26 mn TF1 réalisation Jean Marc Labrousse : extrait

  KEYWESTPRODUCTION · 19 k vues

• 2:16

  Les Boers, la police des Taxis 52 mn W9 Enquête d'action réalisation "Jean Marc Labrousse"

  KEYWESTPRODUCTION · 5 k vues

• 5:41

  Key west Production Jean Marc Labrousse

  KEYWESTPRODUCTION · 300 vues

Top publications · les plus citées

• 1

  Genetics of Usher Syndrome: New Insights From a Meta-analysis

  Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2019

  📚 72 citations🎯 RCR 3.80Top 12% NIH

  Lire l'abstract Crossref ↓

  Objective: To describe the genetic and phenotypic spectrum of Usher syndrome after 6 years of studies by next-generation sequencing, and propose an up-to-date classification of Usher genes in patients with both visual and hearing impairments suggesting Usher syndrome, and in patients with seemingly isolated deafness. Study Design: The systematic review and meta-analysis protocol was based on Cochrane and Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. We performed 1) a meta-analysis of data from 11 next-generation sequencing studies in 684 patients with Usher syndrome; 2) a meta-analysis of data from 21 next-generation studies in 2,476 patients with seemingly isolated deafness, to assess the involvement of Usher genes in seemingly nonsyndromic hearing loss, and thus the proportion of patients at high risk of subsequent retinitis pigmentosa (RP); 3) a statistical analysis of differences between parts 1) and 2). Results: In patients with both visual and hearing impairments, the biallelic disease-causing mutation rate was assessed for each Usher gene to propose a classification by frequency: USH2A: 50% (341/684) of patients, MYO7A: 21% (144/684), CDH23: 6% (39/684), ADGRV1: 5% (35/684), PCDH15: 3% (21/684), USH1C: 2% (17/684), CLRN1: 2% (14/684), USH1G: 1% (9/684), WHRN: 0.4% (3/684), PDZD7 0.1% (1/684), CIB2 (0/684). In patients with seemingly isolated sensorineural deafness, 7.5% had disease-causing mutations in Usher genes, and are therefore at high risk of developing RP. These new findings provide evidence that usherome dysfunction is the second cause of genetic sensorineural hearing loss after connexin dysfunction. Conclusion: These results promote generalization of early molecular screening for Usher syndrome in deaf children.

• 2

  Interactions Between Odorants and Glutathione Transferases in the Human Olfactory Cleft

  Chemical senses · 2020

  📚 28 citations🎯 RCR 2.07

  Lire l'abstract Crossref ↓

  AbstractXenobiotic metabolizing enzymes and other proteins, including odorant-binding proteins located in the nasal epithelium and mucus, participate in a series of processes modulating the concentration of odorants in the environment of olfactory receptors (ORs) and finely impact odor perception. These enzymes and transporters are thought to participate in odorant degradation or transport. Odorant biotransformation results in 1) changes in the odorant quantity up to their clearance and the termination of signaling and 2) the formation of new odorant stimuli (metabolites). Enzymes, such as cytochrome P450 and glutathione transferases (GSTs), have been proposed to participate in odorant clearance in insects and mammals as odorant metabolizing enzymes. This study aims to explore the function of GSTs in human olfaction. Using immunohistochemical methods, GSTs were found to be localized in human tissues surrounding the olfactory epithelium. Then, the activity of 2 members of the GST family toward odorants was measured using heterologously expressed enzymes. The interactions/reactions with odorants were further characterized using a combination of enzymatic techniques. Furthermore, the structure of the complex between human GSTA1 and the glutathione conjugate of an odorant was determined by X-ray crystallography. Our results strongly suggest the role of human GSTs in the modulation of odorant availability to ORs in the peripheral olfactory process.

• 3

  Surgical therapy in intractable benign paroxysmal positional vertigo

  Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2007

  📚 26 citations🎯 RCR 1.41

  Lire l'abstract Crossref ↓

  OBJECTIVESBenign paroxysmal positional vertigo (BPPV) is the most frequent vestibular disorder. Although it is easily cured with canal repositioning maneuvers for the majority of patients, it can be disabling in rare cases. For these patients, surgical solutions may be proposed. The aim of this article is to review the techniques used, the reported cases in the literature, and to discuss their indication in intractable BPPV.STUDY DESIGNLiterature review.MATERIALS AND METHODSAll the articles from 1972 to 2005 that discussed a specific surgical therapy in BPPV were reviewed. Many of them reported cases of operated patients and described original techniques. Some others are anatomic studies that discussed the two techniques used: singular neurectomy and posterior semicircular canal occlusion.RESULTSSingular neurectomy (posterior ampullary nerve transsection) and posterior semicircular canal occlusion are the 2 specific techniques used in intractable BPPV surgery. The numbers of operated cases are 342 and 97, respectively. These small numbers indicate that the procedures are difficult and risk compromising hearing and that a very small population of patients require surgical treatment of BPPV. The operated cases have been decreasing since the early 1990s because of improved management in BPPV. This article summarizes the techniques and their results and proposes a currently recommended practice of surgical therapy in BPPV as well as new insights into intractable BPPVs’ physiopathology.

Publications scientifiques (34) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

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