Docteur LAURENCE HALIMI

Bibliographie

• Larger quality of life gains with asthma support app: a randomised controlled trial

  2025

  ArticleERJ Open Research

• Mid-Term Sequelae of Surviving Patients Hospitalized in Intensive Care Unit for COVID-19 Infection: The REHCOVER Study

  2023

  ArticleJournal of Clinical Medicine

• Health-related quality of life and disease progression in pulmonary arterial hypertension patients: a 3-year study

  2021

  ArticleERJ Open Research

• Will the asthma revolution fostered by biologics also benefit adult ICU patients?

  2021

  ArticleAllergy

• Patient distrust in pharmaceutical companies: an explanation for women under-representation in respiratory clinical trials?

  2020

  ArticleBMC Medical Ethics

• Adverse publicity of serious side effects to healthy volunteers has limited effect on willingness-to-participate in clinical trials

  2019

  ArticleClinical Trials

• Impact of psychological factors on the health-related quality of life of patients treated for pulmonary arterial hypertension

  2018

  ArticleJournal of Psychosomatic Research

• Future treatment for asthma

  2016

  ArticleEuropean Respiratory Review

Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).

Lieu de consultation

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Tarifs & secteur de conventionnement

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Prendre rendez-vous & contact

Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Top publications · les plus citées

• 1

  Patient distrust in pharmaceutical companies: an explanation for women under-representation in respiratory clinical trials?

  BMC medical ethics · 2020

  📚 28 citations🎯 RCR 1.59🔓 Open Access📄 PDF gratuit ↗

  Lire l'abstract Crossref ↓

  Abstract Background Patient skepticism concerning medical innovations can have major consequences for current public health and may threaten future progress, which greatly relies on clinical research. The primary objective of this study is to determine the variables associated with patient acceptation or refusal to participate in clinical research. Specifically, we sought to evaluate if distrust in pharmaceutical companies and associated psychosocial factors could represent a recruitment bias in clinical trials and thus threaten the applicability of their results. Methods This prospective, multicenter survey consisted in the administration of a self-questionnaire to patients during a pulmonology consultation. The 1025 questionnaires distributed collected demographics, socio-professional and basic health literacy characteristics. Patients were asked to rank their level of trust for pharmaceutical companies and indicate their willingness to participate in different categories of research (pre or post marketing, sponsored by an academic institution or pharmaceutical company). Logistic regression was used to determine factors contributing to “trust” versus “distrust” group membership and willingness to participate in each category of research. Results One thousand patients completed the survey, corresponding to a response rate of 97.5%. Data from 838 patients were analyzed in this study. 48.3% of respondents declared that they trusted pharmaceutical companies, while 35.5% declared distrust. Being female (p = 0.042), inactive in the employment market(p = 0.007), and not-knowing the name of one’s disease(p = 0.010) are factors related to declared distrust. Distrust-group membership is associated with unwillingness to participate in certain categories of trials such as pre-marketing and industry-sponsored trials. Conclusion Distrust in pharmaceutical companies is associated with a specific patient profile and with refusal to participate in certain subcategories of trials. This potential recruitment bias may explain the under-representation of certain categories of patients such as women in pre-marketing drug trials.

• 2

  Interference of psychological factors in difficult-to-control asthma

  Respiratory medicine · 2007

  📚 28 citations🎯 RCR 1.07🔓 Open Access📄 PDF gratuit ↗
• 3

  Impact of psychological factors on the health-related quality of life of patients treated for pulmonary arterial hypertension

  Journal of psychosomatic research · 2018

  📚 22 citations🎯 RCR 1.16🔓 Open Access

Publications scientifiques (12) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

Datasets & protocoles partagés

• Additional file 1 of Patient distrust in pharmaceutical companies: an explanation for women under-representation in respiratory clinical trials?

  Dataset2020figshare

  Additional file 1. Questionnaire PROTOACCEPT - French/English bilingual version.

• Patient distrust in pharmaceutical companies: an explanation for women under-representation in respiratory clinical trials?

  Collection2020figshare

  Abstract Background Patient skepticism concerning medical innovations can have major consequences for current public health and may threaten future progress, which greatly relies on clinical research. The primary objecti

• Additional file 1 of Patient distrust in pharmaceutical companies: an explanation for women under-representation in respiratory clinical trials?

  Dataset2020figshare

  Additional file 1. Questionnaire PROTOACCEPT - French/English bilingual version.

• Patient distrust in pharmaceutical companies: an explanation for women under-representation in respiratory clinical trials?

  Collection2020figshare

  Abstract Background Patient skepticism concerning medical innovations can have major consequences for current public health and may threaten future progress, which greatly relies on clinical research. The primary objecti

Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).

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