📇 Rhumatologue · FORT DE FRANCE · (972) · Libéral
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2 raisons identifiées
Praticien-chercheur
5 articles scientifiques publiés — formation continue solide
Délais de RDV courts dans la région
106.4 rhumatos / 100 000 hab. — département bien doté
✨ Génération du profil synthétique IA en cours…
Indicateurs publics agrégés sur 250 M+ d'œuvres scientifiques (OpenAlex, PubMed). Traduits ici en langage patient.
Influence scientifique
Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.
29
29 articles ont été cités au moins 29fois par d'autres chercheurs — preuve que ses travaux sont repris par la communauté médicale.
h-index
Total citations reçues
3 514
Nombre de fois où d'autres équipes ont mentionné ses publications dans leurs propres travaux.
Publications totales
143
Articles, revues et chapitres référencés dans les bases académiques internationales.
Articles influents
50
Publications ayant marqué leur domaine — chacune citée au moins 10 fois par d'autres chercheurs.
i10-index
Thématiques principales
Affiliations FR : CEA CESTA · Centre National de la Recherche Scientifique · Inserm
Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.
Articles déposés en accès libre sur l'archive ouverte des universités françaises (HAL) — gage d'activité de recherche en France.
FLASH: innovative integrated enzymatic-fluorescent labeling for automated muscle fiber typing, metabolic and morphometric analysis
2025ArticleSkeletal Muscle
Laser-activated nanoparticles rewire tumor microenvironment enhancing PD-1 blockade and T cell response in cholangiocarcinoma
2025ArticleHepatology
The enteric nervous system is 10 times stiffer than the brain
2025ArticleBiophysical Journal
Guide des bonnes pratiques pour la gestion des données de la recherche en BioImagerie
2025Ouvrage
Some practical methodologies to assess the overall high temperature (one-sided) steam oxidation protectiveness of chromium-based coatings on a zirconium-based substrate, as Enhanced – Accident Tolerant (Nuclear) Fuels (E-ATF) claddings
2025ArticleJournal of Nuclear Materials
The double-edged role of FASII regulator FabT in Streptococcus pyogenes infection
2024ArticleNature Communications
Exchanges networks and manufacturing techniques in the late medieval Aegean: a case study on the Chalcis Hoard
2024CongrèsArchaeometallurgy in Europe 2024
ARL5b inhibits human rhinovirus 16 propagation and impairs macrophage-mediated bacterial clearance
2024ArticleEMBO Reports
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
CABINET DU DR THOMAS GUILBERT
IM. OPALE SOS MEDECINS RUE ERNEST HEMINGWAY ZAC ETANG Z'ABRICOTS, 97200 FORT DE FRANCE
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
eLife · 2021
Only a fraction of cancer patients benefits from immune checkpoint inhibitors. This may be partly due to the dense extracellular matrix (ECM) that forms a barrier for T cells. Comparing five preclinical mouse tumor models with heterogeneous tumor microenvironments, we aimed to relate the rate of tumor stiffening with the remodeling of ECM architecture and to determine how these features affect intratumoral T cell migration. An ECM-targeted strategy, based on the inhibition of lysyl oxidase, was used. In vivo stiffness measurements were found to be strongly correlated with tumor growth and ECM crosslinking but negatively correlated with T cell migration. Interfering with collagen stabilization reduces ECM content and tumor stiffness leading to improved T cell migration and increased efficacy of anti-PD-1 blockade. This study highlights the rationale of mechanical characterizations in solid tumors to understand resistance to immunotherapy and of combining treatment strategies targeting the ECM with anti-PD-1 therapy.
Annals of the rheumatic diseases · 2016
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2016
ABSTRACT Claudin-16 protein (CLDN16) is a component of tight junctions (TJ) with a restrictive distribution so far demonstrated mainly in the kidney. Here, we demonstrate the expression of CLDN16 also in the tooth germ and show that claudin-16 gene (CLDN16) mutations result in amelogenesis imperfecta (AI) in the 5 studied patients with familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC). To investigate the role of CLDN16 in tooth formation, we studied a murine model of FHHNC and showed that CLDN16 deficiency led to altered secretory ameloblast TJ structure, lowering of extracellular pH in the forming enamel matrix, and abnormal enamel matrix protein processing, resulting in an enamel phenotype closely resembling human AI. This study unravels an association of FHHNC owing to CLDN16 mutations with AI, which is directly related to the loss of function of CLDN16 during amelogenesis. Overall, this study indicates for the first time the importance of a TJ protein in tooth formation and underlines the need to establish a specific dental follow-up for these patients. © 2015 American Society for Bone and Mineral Research.
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Journal of visualized experiments : JoVE · 2025 · Journal Article
Duperray-Susini A, Guilbert T, Fodor J, Lesieur J, et al.
eLife · 2021 · Journal Article
Nicolas-Boluda A, Vaquero J, Vimeux L, Guilbert T, et al.
Stem cells (Dayton, Ohio) · 2019 · Journal Article
Collignon AM, Castillo-Dali G, Gomez E, Guilbert T, et al.
Annals of the rheumatic diseases · 2016 · Journal Article
Ruzehaji N, Frantz C, Ponsoye M, Avouac J, et al.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2016 · Journal Article
Bardet C, Courson F, Wu Y, Khaddam M, et al.
Example Microscopy Metadata JSON files produced using Micro-Meta App to document example microscopy experiments performed at individual core facilities
Example <strong>Microscopy Metadata </strong>(Microscope.JSON and Settings.JSON)<strong> files </strong>produced using<strong> Micro-Meta App </strong>to document the <strong>Hardware Specifications</strong> of example M
Acute stress induces long-term metabolic, functional and structural remodeling of the heart
Takotsubo syndrome, a stress-induced cardiomyopathy mimicking an acute coronary syndrome but formerly considered a benign reversible disease, increases the risk of heart failure and cardiac death. Here, the authors show
Example Microscopy Metadata JSON files produced using Micro-Meta App to document example microscopy experiments performed at individual core facilities
Example <strong>Microscopy Metadata </strong>(Microscope.JSON and Settings.JSON)<strong> files </strong>produced using<strong> Micro-Meta App </strong>to document the <strong>Hardware Specifications</strong> of example M
Acute stress induces long-term metabolic, functional and structural remodeling of the heart
Takotsubo syndrome, a stress-induced cardiomyopathy mimicking an acute coronary syndrome but formerly considered a benign reversible disease, increases the risk of heart failure and cardiac death. Here, the authors show
MetroloJ_QC_Public_CID_OpenData
Public access to online raw data of the MetroloJ_QC project of the GT3M Quality Control working group of the RTmfm. You can download each part individually (archive file format) or the entire dataset (Public_Data_Metrol
The enteric nervous system is 10 times stiffer than the brain
Neural tissues of the central nervous system are among the softest and most fragile in the human body, protected from mechanical perturbation by the skull and the spine. In contrast, the enteric nervous system is embedde
Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).