Docteur XAVIER GUENNOC

Bibliographie

• Efficacy and safety of combination targeted therapies in immune-mediated inflammatory disease: the COMBIO study

  2023

  ArticleDigestive and Liver Disease

• New-onset inflammatory bowel diseases among IL-17 inhibitor-treated patients: results from the case–control MISSIL study

  2022

  ArticleRheumatology

• Calcium pyrophosphate deposition (CPPD) in a liver transplant patient: are hypomagnesemia, tacrolimus or both guilty? A case-based literature review

  2022

  ArticleRheumatology International

• Ruling out septic arthritis risk in a few minutes using mid-infrared spectroscopy in synovial fluids

  2021

  ArticleRheumatology

• Musculoskeletal Symptoms in Patients With Cryopyrin-Associated Periodic Syndromes: A Large Database Study

  2015

  ArticleArthritis & rheumatology

• Is routine viral screening useful in patients with recent-onset polyarthritis of a duration of at least 6 weeks? Results from a nationwide longitudinal prospective cohort study.

  2011

  ArticleArthritis Care & Research = Arthritis Care and Research

• Is screening for hepatitis B and hepatitis C useful in patients with recent-onset polyarthritis? The ESPOIR cohort study.

  2009

  ArticleJournal of Rheumatology

Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).

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Top publications · les plus citées

• 1

  Alopecia areata occurring during anti-TNF therapy: a national multicenter prospective study

  Journal of the American Academy of Dermatology · 2014

  📚 53 citations🎯 RCR 2.28Top 23% NIH🔓 Open Access📄 PDF gratuit ↗
• 2

  Is routine viral screening useful in patients with recent-onset polyarthritis of a duration of at least 6 weeks? Results from a nationwide longitudinal prospective cohort study

  Arthritis care & research · 2011

  📚 26 citations🎯 RCR 1.10

  Lire l'abstract Crossref ↓

  AbstractObjectiveTo study the contribution of routine viral screening tests in patients with early rheumatoid arthritis (RA) or a potential for progressing to RA.MethodsEight hundred thirteen patients with swelling of at least 2 joints for at least 6 weeks and a symptom duration of less than 6 months in the ESPOIR cohort were screened for parvovirus B19 (IgG and IgM anti–parvovirus B19 antibodies), hepatitis B virus (HBV; hepatitis B surface antigen), hepatitis C virus (HCV; anti‐HCV antibodies), and human immunodeficiency virus (HIV; anti–HIV‐1 and ‐2 antibodies).ResultsParvovirus B19 testing was performed in 806 patients and showed longstanding immunity in 574 (71.2%) and no antibodies in 223 (27.7%). Among the 9 remaining patients (7 IgG positive/IgM positive, 1 IgG negative/IgM positive, and 1 IgG indeterminate/IgM positive), only 2 (0.25%; 95% confidence interval [95% CI] 0–0.99%) had a positive polymerase chain reaction test for parvovirus B19; these patients (women ages 34 and 40 years) had no extraarticular signs. HIV seroprevalence was 0.12% (n = 1 of 813; 95% CI 0.01–0.8%) and HCV seroprevalence was 0.86% (n = 7 of 808, 95% CI 0.38–1.86%). HCV‐related arthritis was diagnosed in 4 patients (0.5%). HCV‐seropositive patients had significantly higher transaminase levels than the other patients (P = 0.001), with no significant differences for the other laboratory data. HBV seroprevalence was 0.12% (n = 1 of 808; 95% CI 0.01–0.8%); the positive HBV status was known before study inclusion, and the patient had no diagnosis of HBV‐related arthritis. Finally, routine viral testing identified 2 patients with parvovirus B19 infection and 3 with HBV infection (0.6%; 95% CI 0.2–1.5%). Cost was €85.05 per patient (total €68,720).ConclusionRoutine serologic testing did not contribute substantially to the diagnosis in this context.

• 3

  Musculoskeletal symptoms in patients with cryopyrin-associated periodic syndromes: a large database study

  Arthritis & rheumatology (Hoboken, N.J.) · 2015

  📚 19 citations

  Lire l'abstract Crossref ↓

  ObjectiveTo determine the type and frequency of musculoskeletal symptoms at onset and during followup of cryopyrin‐associated periodic syndromes (CAPS).MethodsWe retrospectively recorded the articular and muscular symptoms of patients with CAPS followed up in French hospitals. Data were presented as frequencies or the median (range), and patient groups were compared using chi‐square test, Fisher's exact test, and Mann‐Whitney test.ResultsThe study included 133 patients (33 children), 20 with familial cold autoinflammatory syndrome, 88 with Muckle‐Wells syndrome, 22 with chronic infantile neurologic, cutaneous, articular syndrome, and 3 with unclassified CAPS. The median age was 35 years (range 0–78 years) at the time of the study, 1 year (range 0–41 years) at symptom onset, and 23 years (range 0–58 years) at diagnosis. The disease was sporadic in 17% of the patients. Cutaneous symptoms predominated at onset (77%), followed by articular symptoms (30%). The p.Thr348Met and p.Arg260Trp NLRP3 mutations were significantly associated with the presence and absence of articular symptoms at onset, respectively. During followup, 86% of the patients had musculoskeletal symptoms, 88% had arthralgia, and 58% had arthritis, but only 9% had joint destruction. Tendinopathies occurred in 21.5% of the patients, tender points in 16.5%, and myalgia in 33%. Only 3 patients had typical knee deformities. Radiographs were rarely obtained. Except for bone deformities, osteoarticular symptoms occurred at similar frequencies in the different CAPS phenotypes.ConclusionJoint manifestations were frequent in all CAPS phenotypes. Bone deformities were rare. Musculoskeletal manifestations varied within given families but tended to worsen over time.

Publications scientifiques (11) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

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