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Auteur de référence en rhumatologie
26 articles scientifiques publiés — un praticien à la pointe de la recherche
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120.1 rhumatos / 100 000 hab. — département bien doté
✨ Génération du profil synthétique IA en cours…
HOPITAL NORD - CHU38
BD DE LA CHANTOURNE, 38700 LA TRONCHE
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Oral oncology · 2019
Inflammatory bowel diseases · 2022
AbstractBackgroundAlthough histological healing is raising interest in ulcerative colitis to predict recurrence, its meaning in Crohn’s disease (CD) remains unknown. We aimed to study the performances of different histological indices to predict recurrence of CD patients with mucosal healing.MethodsCrohn’s disease patients with mucosal healing diagnosed between 2010 and 2018 were included if there was available clinical and endoscopical data. Nancy Histological index (NHI), Geboes score (GS), Robarts Histopathology index (RHI), Global Histological Disease Activity Score (GHAS), and Inflammatory Bowel Disease—Distribution Chronicity Activity score (IBD-DCA) were independently assessed by 3 pathologists.ResultsEighty-eight patients were included, of which 28 relapsed (32%) within 30.5 months. All 4 histological indices were associated with recurrence, with significant relapse risk (NHI, odds ratio [OR], 1.67; GHAS, OR, 2.33; RHI, OR, 1.19; GS, OR, 2.09; and IBD-DCA, OR, 2.14). Microscopic activity was significantly associated with relapse only with the IBD-DCA score. Predicting performances of all these scores were poor. Calibration curves indicate that the GHAS and IBD-DCA are the closest to the ideal predicted probability curve and thus could better predict recurrence than the other scores. Interobserver agreement varied from poor for GHAS (k = .39) to good for RHI (k = .68).ConclusionsHistological scores are valuable indicators to predict recurrence. Histological assessment of activity seems insufficient to predict CD course with most of the score evaluated, highlighting the need for new indices or adaptation of actual scores to CD specificities.
Trials · 2022
AbstractBackgroundThere is widespread agreement that the integration of cessation services in lung cancer screening (LCS) is essential for achieving the full benefits of LCS with low-dose computed tomography (LDCT). There is a formidable knowledge gap about how to best design feasible, effective, and scalable cessation services in LCS facilities. A collective of NCI-funded clinical trials addressing this gap is the Smoking Cessation at Lung Examination (SCALE) Collaboration.MethodsThe Cessation and Screening to Save Lives (CASTL) trial seeks to advance knowledge about the reach, effectiveness, and implementation of tobacco treatment in lung cancer screening. We describe the rationale, design, evaluation plan, and interventions tested in this multiphase optimization strategy trial (MOST). A total of 1152 screening-eligible current smokers are being recruited from 18 LCS sites (n= 64/site) in both academic and community settings across the USA. Participants receive enhanced standard care (cessation advice and referral to the national Quitline) and are randomized to receive additional tobacco treatment components (motivational counseling, nicotine replacement patches/lozenges, message framing). The primary outcome is biochemically validated, abstinence at 6 months follow-up. Secondary outcomes are self-reported smoking abstinence, quit attempts, and smoking reduction at 3 and 6 months. Guided by the Implementation Outcomes Framework (IOF), our evaluation includes measurement of implementation processes (reach, fidelity, acceptability, appropriateness, sustainability, and cost).ConclusionWe will identify effective treatment components for delivery by LCS sites. The findings will guide the assembly of an optimized smoking cessation package that achieves superior cessation outcomes. Future trials can examine the strategies for wider implementation of tobacco treatment in LDCT-LCS sites.Trial registrationClinicalTrials.govNCT03315910
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
The American journal of tropical medicine and hygiene · 2026 · Journal Article
Delcher C, Park C, Bae J, Pierre DM, et al.
Journal of gynecology obstetrics and human reproduction · 2025 · Journal Article
Adrien C, François M, Clotilde P, Camille A, et al.
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference · 2025 · Journal Article
G A, C G, C J M, B L, et al.
Neurobiology of disease · 2025 · Journal Article
Camille H, Pierre G
BMC emergency medicine · 2025 · Journal Article
Augustine L, Xavier F, Camille D, Mathilde Q
Innovations in pharmacy · 2024 · Journal Article
Yolene G, Ravenell J, Steptoe R, Douglas D, et al.
Annals of the rheumatic diseases · 2023 · Letter
C SK, Ahmed S, Shenoy V, Menon AR, et al.
Inflammatory bowel diseases · 2022 · Journal Article
Marion L, Amélie B, Zoubir D, Guillaume C, et al.
Trials · 2022 · Clinical Trial Protocol
Ostroff JS, Shelley DR, Chichester LA, King JC, et al.
Journal of the American Medical Directors Association · 2020 · Letter
Camille S, Patrick H, Clarisse D, Charifa N, et al.
Injury · 2020 · Journal Article
Camille C, Alexandre C, Vincent R, Kevin K, et al.
Oral oncology · 2019 · Clinical Trial, Phase III
Misiukiewicz K, Gupta V, Miles BA, Bakst R, et al.
Cureus · 2025 · Case Reports
C P, Ann Jose J, Verma G, Priya V L, et al.
Cureus · 2024 · Case Reports
Ramanan A, Balasubramanian V, C R, Sami P
JBJS case connector · 2024 · Case Reports
C A, Raju A, Meleppuram JJ, Nair AV, et al.
The American journal of case reports · 2023 · Case Reports
Inesse AA, Ilaria R, Camille O
Advances in protein chemistry and structural biology · 2026 · Journal Article
Loganathan T, Madhulekha S, Zayed H, C GPD
Lupus · 2023 · Journal Article
Patil A, Shobha V, Shenoy P, S C, et al.
Cureus · 2019 · Case Reports
Thomas M, Robert A, Kuruvilla N, C U
Complementary therapies in medicine · 2025 · Journal Article
Gan L, Tang Q, Zhang Z, Camille CR, et al.
Malaria journal · 2025 · Journal Article
Gutman JR, Onikpo F, Alao M, Niemczura J, et al.
European journal of pediatrics · 2024 · Journal Article
Yıldız Ç, Küçükali B, C SSB, Şenol PE, et al.
Journal of travel medicine · 2020 · Letter
Pauline V, Camille B, Philippe B, Vincent F, et al.
European journal of pediatrics · 2024 · Journal Article
Yıldız Ç, Küçükali B, C SSB, Şenol PE, et al.
European journal of obstetrics & gynecology and reproductive biology: X · 2025 · Journal Article
Perrine T, Camille B, Serge A, Serge D, et al.
Cureus · 2024 · Case Reports
Ramanan A, Balasubramanian V, C R, Sami P
Complementary therapies in medicine · 2025 · Journal Article
Gan L, Tang Q, Zhang Z, Camille CR, et al.
Cureus · 2025 · Case Reports
Lakshme I, C A, Senthil N, Pandurangan V
Cureus · 2026 · Case Reports
R S, Nanda M S, Adalarasan S, Subramanian Y, et al.