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Rhumatologue

Docteur ALAIN DUVAL

RPPS 10002614237
📊 Reconnaissance scientifique : 16/100📝 111 articles publiés📚 HAL (8)

Diplômes

🎓 DES & spécialité ordinale

  • Rhumatologie (SM)

📚 CES (Certificat d'Études Spéciales)

  • CES Rhumatologie

🎓 Diplômes

  • DE Docteur en médecine

Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.

Activité de recherche & publications

Source : bases de données publiques (OpenAlex, PubMed).

h-index

16

h articles cités ≥ h fois chacun. Un h de 16 = 16 publications avec 16+ citations.

Citations

781

Publications

111

i10-index

27

Thématiques principales

  • Ancient and Medieval Archaeology Studies ×30
  • Laser-Plasma Interactions and Diagnostics ×22
  • Cultural Heritage Materials Analysis ×16
  • Laser-induced spectroscopy and plasma ×14
  • Ancient Mediterranean Archaeology and History ×14

Affiliations FR : Commissariat à l'Énergie Atomique et aux Énergies Alternatives · CEA DAM Île-de-France

Voir sur OpenAlex ↗

Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.

Bibliographie

Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).

Lieu de consultation

Tarifs & secteur de conventionnement

Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).

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Prendre rendez-vous & contact

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Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Articles de presse (7)

Source : Google News (recherche par nom complet — homonymes possibles, vérifier le contenu).

Top publications · les plus citées

  • 1
    Humoral Response after SARS-CoV-2 mRNA Vaccination in a Cohort of Hemodialysis Patients and Kidney Transplant Recipients

    Journal of the American Society of Nephrology : JASN · 2021

    📚 137 citations🎯 RCR 6.91Top 5% NIH🔓 Open Access
    Lire l'abstract Crossref ↓

    Significance Statement Data are lacking on the humoral response to COVID-19 vaccination in kidney transplant recipients and patients on hemodialysis. This study of humoral response to an mRNA vaccine in 78 patients undergoing hemodialysis, 74 kidney transplant recipients, and seven healthy controls found that anti–SARS-CoV-2 antibodies peaked at day 36 postvaccination among controls, whereas patients on hemodialysis had lower titers that peaked at day 58, and only three patients who received kidney transplant exhibited detectable antibody levels. Among patients on hemodialysis, age <75 years, serum albumin, and Kt/V were positively correlated with serological response; those who were nonresponders to the HBV vaccine had the lowest anti–SARS-CoV-2 antibody titers. These findings suggest that postvaccination humoral response is strongly inhibited by immunosuppressant therapy in kidney transplant recipients and is reduced by the uremic condition in patients on hemodialysis. Background Kidney transplant recipients and patients receiving hemodialysis are immunocompromised populations that are prioritized for COVID-19 vaccination but were excluded from clinical trials of SARS-CoV-2 mRNA vaccines. Antibody titers and rates of seroconversion after vaccination are lower among patients with CKD and those taking immunosuppressants compared with controls. Data are lacking regarding their humoral response to vaccination to prevent COVID-19. Methods This investigation of early serological response after COVID-19 vaccination with the Pfizer/BioNTech (BNT162b2) mRNA vaccine included 78 patients undergoing hemodialysis, 74 kidney transplant recipients, and seven healthy controls. We recorded data from the medical file for various clinical parameters, including response to hepatitis B vaccination, and measured antibody titers against SARS-CoV-2 at 0, 14, 28, 36, and 58 days after the first injection. Results In controls, we detected antibodies at a positive level (>13 arbitrary units per ml; AU/ml) at day 14 postinjection, which increased progressively to peak at day 36 (1082 AU/ml; interquartile range [IQR], 735.0–1662.0). Patients undergoing hemodialysis had lower titers that peaked at day 58 (276 AU/ml; IQR, 83.4–526.0). We detected a positive antibody level in only three transplant recipients at day 36. In patients on hemodialysis, those aged <75 years had a higher antibody response versus those aged >75 years, and serum albumin and Kt/V were positively correlated with serological response (P<0.04 and P<0.0, respectively); nonresponders to HBV vaccine had the lowest anti–SARS-CoV-2 antibody titers. Conclusions Our results suggest that the postvaccination humoral response is strongly inhibited by immunosuppressant therapy in kidney transplant recipients, and is reduced by the uremic condition in patients undergoing hemodialysis.

  • 2
    Clinical characteristics and outcome of respiratory syncytial virus infection among adults hospitalized with influenza-like illness in France

    Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2017

    📚 93 citations🎯 RCR 4.15Top 10% NIH🔓 Open Access📄 PDF gratuit ↗
  • 3
    Endothelial dysfunction in systemic lupus patients with low disease activity: evaluation by quantification and characterization of circulating endothelial microparticles, role of anti-endothelial cell antibodies

    Rheumatology (Oxford, England) · 2010

    📚 44 citations🎯 RCR 1.31

Publications scientifiques (17) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

Transversal14

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Lupus2

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Biomarqueurs / Auto-Ac1

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Datasets & protocoles partagés

Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).

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