📇 Rhumatologue · POITIERS · (86) · Libéral

MME JANE DECOUST

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Auteur de référence en rhumatologie
21 articles scientifiques publiés — un praticien à la pointe de la recherche
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📍 POITIERS (86)LibéralRPPS 10100915262

✨ Génération du profil synthétique IA en cours…

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136 BIS RUE DE LA PIERRE LEVEE, 86000 POITIERS
☎ 0549613636Activité de soin et de pharmacie

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Top publications · les plus citées

The Theranostic Genome

Nature communications · 2024

📚 5 citations🔓 Open Access📄 PDF gratuit ↗

Cognitive processing therapy (CPT) versus individual drug counseling (IDC) for PTSD for veterans with opioid use disorder maintained on buprenorphine

The American journal on addictions · 2024

📚 3 citations🎯 RCR 1.01🩺 Clinique

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AbstractBackground and ObjectivesThere are high rates of comorbidity between posttraumatic stress disorder (PTSD) and opioid use disorder (OUD). Evidence‐based trauma‐focused psychotherapies such as Cognitive Processing Therapy (CPT) are a first‐line treatment for PTSD. Veterans with OUD are treated primarily in substance use disorder (SUD) clinics where the standard of care is drug counseling; they often do not have access to first‐line PTSD treatments. This study tested whether CPT can be conducted safely and effectively in veterans with comorbid OUD treated with buprenorphine.MethodsThis 12‐week, 2‐site, randomized clinical trial (RCT) included open‐label randomization to two groups: (a) CPT versus (b) Individual Drug Counselling (IDC) in veterans with PTSD and comorbid OUD who were maintained on buprenorphine (N = 38).ResultsVeterans randomized to either IDC (n = 18) or CPT (n = 20) showed a significant reduction in self‐reported PTSD symptoms over time as measured by the PTSD checklist (PCL‐5) but there were no treatment group differences; there was some indication that reduction in PTSD symptoms in the CPT group were sustained in contrast to the IDC group. Recruitment was significantly impacted by COVID‐19 pandemic, so this study serves as a proof‐of‐concept pilot study.Discussion and ConclusionsVeterans with OUD and PTSD can safely and effectively participate in evidence‐based therapy for PTSD; further work should confirm that trauma‐focused treatment may be more effective in leading to sustained remission of PTSD symptoms than drug counseling.Scientific SignificanceThis is the first study to evaluate CPT for PTSD in the context of buprenorphine treatment for OUD.

The Global Prevalence of Antibiotic Resistance and Shiga Toxin-Producing Escherichia coli in Chickens: A Systematic Review and Meta-Analysis (2011-2024)

Antibiotics (Basel, Switzerland) · 2025

📚 2 citations🔓 Open Access📄 PDF gratuit ↗

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Background: Shiga toxin-producing E. coli (STEC) are important foodborne pathogens that cause serious public health consequences worldwide. This study conducted a systematic review and meta-analysis of the global prevalence of antibiotic resistance and STEC in chickens. Methods: The assessment of previous study records was carried out following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Heterogeneity between studies was assessed using Cochrane’s Q test and I2 test statistics based on the random effects model, and comprehensive meta-analysis (CMA) software v4.0 was used to analyse the pooled prevalence estimate (PPE) of antibiotic resistance and STEC in chickens. Results: A total of 61 studies comprising 823 STEC from 18 countries were included in this study. The overall pooled prevalence of STEC was 8.9% (95% CI: 0.620–0.126). m-PCR assay showed the highest PPE of 21.0% (95%: 0.088–0.420). stx1 had the higher PPE of 12.9% (95%: 0.081–0.199), while stx2 had a PPE of 11.8% (95%: 0.077–0.176). Furthermore, the serotype O157 had the higher PPE of 80.5% (95%: 0.520–0.940). The isolates were resistant to the following antibiotics: amoxicillin and clavulanic acid, chloramphenicol, tetracycline, ciprofloxacin, gentamycin, ampicillin, neomycin, and amoxicillin. Conclusions: These findings may assist in the prevention and control of STEC in chickens globally. To minimise the spread of STEC and antibiotic resistance, future foodborne pathogen prevention and control programmes should prioritise increasing laboratory capacity for the early identification of antibiotic resistance.

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MME JANE DECOUST

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Top publications · les plus citées

Publications scientifiques (21) — classées par pathologie

Transversal7

Revue générale3

Santé mentale / fatigue3

Épidémiologie & registres2

Pédiatrie2

Revue / méta-analyse2

Génétique1

Gériatrie1

Lupus1

SAPL1

Vraie vie / RWE1

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