Docteur MARIE CHRISTINE DE VERNEJOUL
✨ Profil synthétique
IA · 06/05/2026Le Docteur Marie Christine De Vernejoul est un rhumatologue avec une production scientifique significative, comme en témoignent son h-index de 33 et ses 97 publications. Ses recherches se concentrent principalement sur le métabolisme osseux, les maladies osseuses, la santé osseuse et l'ostéoporose, ainsi que sur les troubles du tissu conjonctif. Ses travaux académiques incluent également des études génétiques, épidémiologiques et des essais cliniques.
Expertises présumées
- Ostéoporose
- Maladies du métabolisme osseux
- Troubles parathyroïdiens
- Maladies du tissu conjonctif
- Génétique des maladies osseuses
- Épidémiologie des maladies rhumatismales
- Essais cliniques en rhumatologie
Synthèse automatique à partir des sources publiques (HAL, OpenAlex, theses.fr, ClinicalTrials.gov, FAI²R, ANS). Pas une évaluation clinique. Le médecin peut corriger via son compte.
Diplômes
🎓 DES & spécialité ordinale
- Rhumatologie (SM)
📚 CES (Certificat d'Études Spéciales)
- CES Rhumatologie
🎓 Diplômes
- DE Docteur en médecine
Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.
Activité de recherche & publications
Source : bases de données publiques (OpenAlex, PubMed).
h-index
33
h articles cités ≥ h fois chacun. Un h de 33 = 33 publications avec 33+ citations.
Citations
3 843
Publications
97
i10-index
58
Thématiques principales
- Bone Metabolism and Diseases ×30
- Bone health and osteoporosis research ×29
- Bone health and treatments ×29
- Parathyroid Disorders and Treatments ×16
- Connective tissue disorders research ×8
Affiliations FR : Inserm · Bioscar · Hôpital Lariboisière
Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.
Bibliographie
Compromised Volumetric Bone Density and Microarchitecture in Men With Congenital Hypogonadotropic Hypogonadism
2021ArticleJournal of Clinical Endocrinology and Metabolism
Role of the captured retroviral envelope syncytin-B gene in the fusion of osteoclast and giant cell precursors and in bone resorption, analyzed ex vivo and in vivo in syncytin-B knockout mice
2019ArticleBone Reports
Variations of SOST mRNA expression in human bone are associated with DNA polymorphism and DNA methylation in the SOST gene
2016ArticleBONE
Differentially expressed genes in autosomal dominant osteopetrosis type II osteoclasts reveal known and novel pathways for osteoclast biology
2014ArticleLaboratory Investigation
Serotonin 2B receptor (5-HT2B R) signals through prostacyclin and PPAR-ß/δ in osteoblasts.
2012ArticlePLoS ONE
Modifications osseuses chez les conjoints ayant partagé le même mode de vie pendant 40 ans
2011ArticleRevue du Rhumatisme
Bone changes in spouses having shared lifestyle for 40years
2011ArticleJoint Bone Spine
Strontium ranelate decreases the incidence of new caudal vertebral fractures in a growing mouse model with spontaneous fractures by improving bone microarchitecture
2011ArticleOsteoporosis International
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
Lieu de consultation
Tarifs & secteur de conventionnement
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Prendre rendez-vous & contact
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Top publications · les plus citées
- 1Strontium ranelate reduces the risk of nonvertebral fractures in postmenopausal women with osteoporosis: Treatment of Peripheral Osteoporosis (TROPOS) study
The Journal of clinical endocrinology and metabolism · 2005
- 2Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density
American journal of human genetics · 2003
- 3Strontium ranelate: dose-dependent effects in established postmenopausal vertebral osteoporosis--a 2-year randomized placebo controlled trial
The Journal of clinical endocrinology and metabolism · 2002
Publications scientifiques (50) — classées par pathologie
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Transversal45
▼
Transversal45
▼- Compromised Volumetric Bone Density and Microarchitecture in Men With Congenital Hypogonadotropic Hypogonadism
The Journal of clinical endocrinology and metabolism · 2021 · Journal Article
Ostertag A, Papadakis GE, Collet C, Trabado S, et al.
📚 17 cit.🎯 RCR 1.64🔬→🩺 Translationnel - Serotonin Is Involved in Autoimmune Arthritis through Th17 Immunity and Bone Resorption
The American journal of pathology · 2016 · Journal Article
Chabbi-Achengli Y, Coman T, Collet C, Callebert J, et al.
📚 49 cit.🎯 RCR 1.71 - Ankle-brachial index and bone turnover in patients on dialysis
Journal of the American Society of Nephrology : JASN · 2015 · Journal Article
London GM, Marchais SJ, Guérin AP, de Vernejoul MC
📚 30 cit.🎯 RCR 1.22🔬→🩺 Translationnel - When, how, and why a bone biopsy should be performed in patients with chronic kidney disease
Seminars in nephrology · 2014 · Journal Article
Torres PU, Bover J, Mazzaferro S, de Vernejoul MC, et al.
📚 48 cit.🎯 RCR 2.02🔬→🩺 Translationnel - Bone status and fractures in 85 adults with Wilson's disease
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2014 · Journal Article
Quemeneur AS, Trocello JM, Ea HK, Ostertag A, et al.
📚 25 cit.🎯 RCR 1.17🔬→🩺 Translationnel - Cortical measurements of the tibia from high resolution peripheral quantitative computed tomography images: a comparison with synchrotron radiation micro-computed tomography
Bone · 2014 · Journal Article
Ostertag A, Peyrin F, Fernandez S, Laredo JD, et al.
📚 33 cit.🎯 RCR 1.56🔬→🩺 Translationnel - Serotonin 2B receptor (5-HT2B R) signals through prostacyclin and PPAR-ß/δ in osteoblasts
PloS one · 2013 · Journal Article
Chabbi-Achengli Y, Launay JM, Maroteaux L, de Vernejoul MC, et al.
📚 12 cit. - A case-control study of fractures in men with idiopathic osteoporosis: fractures are associated with older age and low cortical bone density
Bone · 2013 · Journal Article
Ostertag A, Collet C, Chappard C, Fernandez S, et al.
📚 20 cit.🔬→🩺 Translationnel - Osteoporosis in young adults: pathophysiology, diagnosis, and management
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2012 · Journal Article
Ferrari S, Bianchi ML, Eisman JA, Foldes AJ, et al.
📚 176 cit.🎯 RCR 7.01🔬→🩺 Translationnel - Targeting bone alleviates osteoarthritis in osteopenic mice and modulates cartilage catabolism
PloS one · 2012 · Journal Article
Funck-Brentano T, Lin H, Hay E, Ah Kioon MD, et al.
📚 43 cit.🎯 RCR 1.57🔬→🩺 Translationnel - Effects of risedronate in Runx2 overexpressing mice, an animal model for evaluation of treatment effects on bone quality and fractures
Calcified tissue international · 2011 · Evaluation Study
Geoffroy V, Paschalis EP, Libouban H, Blouin S, et al.
📚 3 cit. - Increased bone resorption and osteopenia in Dlx5 heterozygous mice
Journal of cellular biochemistry · 2009 · Journal Article
Samee N, Geoffroy V, Marty C, Schiltz C, et al.
📚 8 cit. - Bone mineral density in patients with rapidly destructive or common hip osteoarthritis
Clinical and experimental rheumatology · 2009 · Journal Article
Richette P, Vicaut E, de Vernejoul MC, Orcel P, et al.
📚 14 cit.🔬→🩺 Translationnel - Vertebral fractures are associated with increased cortical porosity in iliac crest bone biopsy of men with idiopathic osteoporosis
Bone · 2009 · Journal Article
Ostertag A, Cohen-Solal M, Audran M, Legrand E, et al.
📚 35 cit.🎯 RCR 1.11🔬→🩺 Translationnel - Geographical variation in DXA bone mineral density in young European men and women. Results from the Network in Europe on Male Osteoporosis (NEMO) study
Bone · 2008 · Journal Article
Kaptoge S, da Silva JA, Brixen K, Reid DM, et al.
📚 32 cit.🎯 RCR 1.24🔬→🩺 Translationnel - Sclerosing bone disorders
Best practice & research. Clinical rheumatology · 2008 · Journal Article
de Vernejoul MC
📚 45 cit.🎯 RCR 1.16🔬→🩺 Translationnel - The serotonin 5-HT2B receptor controls bone mass via osteoblast recruitment and proliferation
FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2008 · Journal Article
Collet C, Schiltz C, Geoffroy V, Maroteaux L, et al.
📚 92 cit.🎯 RCR 2.52🔬→🩺 Translationnel - Role of DLX regulatory proteins in osteogenesis and chondrogenesis
Critical reviews in eukaryotic gene expression · 2007 · Journal Article
Samee N, de Vernejoul MC, Levi G
📚 26 cit. - Complex segregation analysis accounting for GxE of bone mineral density in European pedigrees selected through a male proband with low BMD
Annals of human genetics · 2007 · Journal Article
Pelat C, Van Pottelbergh I, Cohen-Solal M, Ostertag A, et al.
📚 7 cit. - Over-expression of TIMP-1 in osteoblasts increases the anabolic response to PTH
Bone · 2007 · Journal Article
Merciris D, Schiltz C, Legoupil N, Marty-Morieux C, et al.
📚 20 cit. - Estradiol inhibits adhesion and promotes apoptosis in murine osteoclasts in vitro
The Journal of steroid biochemistry and molecular biology · 2006 · Journal Article
Saintier D, Khanine V, Uzan B, Ea HK, et al.
📚 43 cit.🎯 RCR 1.00 - [New therapeutic approaches to osteoporosis]
Annales d'endocrinologie · 2006 · Journal Article
de Vernejoul MC
- Looking at calcimimetics impact on hypercalcemia of immobilization: hypotheses and a case study
Hemodialysis international. International Symposium on Home Hemodialysis · 2006 · Case Reports
Roueff S, Saint Georges M, Chuong VT, Abbassi A, et al.
📚 1 cit.🔬→🩺 Translationnel - LRP5 gene polymorphisms and idiopathic osteoporosis in men
Bone · 2005 · Journal Article
Ferrari SL, Deutsch S, Baudoin C, Cohen-Solal M, et al.
📚 56 cit.🎯 RCR 1.37🔬→🩺 Translationnel - Cannabinoid receptor type 2 gene is associated with human osteoporosis
Human molecular genetics · 2005 · Comparative Study
Karsak M, Cohen-Solal M, Freudenberg J, Ostertag A, et al.
📚 157 cit.🎯 RCR 3.81 - LRP5 mutations in osteoporosis-pseudoglioma syndrome and high-bone-mass disorders
Joint bone spine · 2005 · Journal Article
Levasseur R, Lacombe D, de Vernejoul MC
📚 71 cit.🎯 RCR 1.51🔬→🩺 Translationnel - Strontium ranelate reduces the risk of nonvertebral fractures in postmenopausal women with osteoporosis: Treatment of Peripheral Osteoporosis (TROPOS) study
The Journal of clinical endocrinology and metabolism · 2005 · Clinical Trial
Reginster JY, Seeman E, De Vernejoul MC, Adami S, et al.
📚 682 cit.🎯 RCR 20.93🩺 Clinique - [Genetics of osteoporosis]
La Revue de medecine interne · 2004 · English Abstract
Cohen-Solal M, de Vernejoul MC
📚 2 cit. - TNF-alpha antibodies and osteoprotegerin decrease systemic bone loss associated with inflammation through distinct mechanisms in collagen-induced arthritis
Bone · 2004 · Journal Article
Saidenberg-Kermanac'h N, Corrado A, Lemeiter D, deVernejoul MC, et al.
📚 95 cit.🎯 RCR 2.29🔬→🩺 Translationnel - Severe osteopenia in CFTR-null mice
Bone · 2004 · Comparative Study
Dif F, Marty C, Baudoin C, de Vernejoul MC, et al.
📚 68 cit.🎯 RCR 1.72🔬→🩺 Translationnel - Interleukin-4 cellular gene therapy and osteoprotegerin decrease inflammation-associated bone resorption in collagen-induced arthritis
Journal of clinical immunology · 2004 · Journal Article
Saidenberg-Kermanac'h N, Bessis N, Lemeiter D, de Vernejoul MC, et al.
📚 34 cit. - In vivo inhibition of osteoblastic metalloproteinases leads to increased trabecular bone mass
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2004 · Comparative Study
Geoffroy V, Marty-Morieux C, Le Goupil N, Clement-Lacroix P, et al.
📚 54 cit.🎯 RCR 1.29🔬→🩺 Translationnel - BMD is reduced in HIV-infected men irrespective of treatment
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2004 · Journal Article
Amiel C, Ostertag A, Slama L, Baudoin C, et al.
📚 117 cit.🎯 RCR 3.11🔬→🩺 Translationnel - 17beta-estradiol downregulates beta3-integrin expression in differentiating and mature human osteoclasts
Journal of cellular physiology · 2004 · Comparative Study
Saintier D, Burde MA, Rey JM, Maudelonde T, et al.
📚 18 cit.🔬→🩺 Translationnel - Role for osteoprotegerin in rheumatoid inflammation
Joint bone spine · 2004 · Journal Article
Saidenberg-Kermanac'h N, Cohen-Solal M, Bessis N, De Vernejoul MC, et al.
📚 71 cit.🎯 RCR 1.66🔬→🩺 Translationnel - Osteoporosis in patients on long-term home parenteral nutrition: a longitudinal study
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2003 · Journal Article
Cohen-Solal M, Baudoin C, Joly F, Vahedi K, et al.
📚 54 cit.🎯 RCR 1.99🔬→🩺 Translationnel - Bone mineral density, biochemical markers and skeletal fractures in haemodialysis patients
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2003 · Evaluation Study
Ureña P, Bernard-Poenaru O, Ostertag A, Baudoin C, et al.
📚 120 cit.🎯 RCR 3.54🔬→🩺 Translationnel - Bone mineral measurements in mice: comparison of two devices
Journal of clinical densitometry : the official journal of the International Society for Clinical Densitometry · 2003 · Comparative Study
Kolta S, De Vernejoul MC, Meneton P, Fechtenbaum J, et al.
📚 14 cit. - [Bone remodeling]
Therapie · 2003 · English Abstract
Cohen-Solal M, de Vernejoul MC
📚 1 cit. - [Estrogens, androgens, and osteoporosis in men]
Annales d'endocrinologie · 2003 · English Abstract
de Vernejoul MC, Cohen Solal M
📚 4 cit. - Six novel missense mutations in the LDL receptor-related protein 5 (LRP5) gene in different conditions with an increased bone density
American journal of human genetics · 2003 · Journal Article
Van Wesenbeeck L, Cleiren E, Gram J, Beals RK, et al.
📚 419 cit.🎯 RCR 8.29🔬→🩺 Translationnel - Reduced bone mineral density in postmenopausal women self-reporting premenopausal wrist fractures
Bone · 2002 · Comparative Study
Fiorano-Charlier C, Ostertag A, Aquino JP, de Vernejoul MC, et al.
📚 18 cit.🔬→🩺 Translationnel - Osteoprotegerin and inflammation
European cytokine network · 2002 · Journal Article
Saidenberg Kermanac'h N, Bessis N, Cohen-Solal M, De Vernejoul MC, et al.
📚 49 cit.🎯 RCR 1.19🔬→🩺 Translationnel - Bones, genes and fractures: workshop on the genetics of osteoporosis: from basic to clinical research
EMBO reports · 2002 · Journal Article
Levi G, Geoffroy V, Palmisano G, de Vernejoul MC
📚 12 cit. - [Pathophysiology and genetics of osteoporosis]
Annales de medecine interne · 2000 · Journal Article
Cohen-Solal M, Marie P, De Vernejoul MC
📚 1 cit.
Génétique2
▼
Génétique2
▼- Genome-wide linkage screen of bone mineral density (BMD) in European pedigrees ascertained through a male relative with low BMD values: evidence for quantitative trait loci on 17q21-23, 11q12-13, 13q12-14, and 22q11
The Journal of clinical endocrinology and metabolism · 2008 · Journal Article
Kaufman JM, Ostertag A, Saint-Pierre A, Cohen-Solal M, et al.
📚 31 cit.🔬→🩺 Translationnel - Genetic and environmental factors affect bone density variances of families of men and women with osteoporosis
The Journal of clinical endocrinology and metabolism · 2002 · Journal Article
Baudoin C, Cohen-Solal ME, Beaudreuil J, De Vernejoul MC
📚 21 cit.
Épidémiologie & registres1
▼
Épidémiologie & registres1
▼- Relationship between change in femoral neck bone mineral density and hip fracture incidence during treatment with strontium ranelate
Current medical research and opinion · 2007 · Journal Article
Bruyère O, Roux C, Badurski J, Isaia G, et al.
📚 39 cit.🎯 RCR 1.13🔬→🩺 Translationnel
Essai clinique1
▼
Essai clinique1
▼- Strontium ranelate: dose-dependent effects in established postmenopausal vertebral osteoporosis--a 2-year randomized placebo controlled trial
The Journal of clinical endocrinology and metabolism · 2002 · Clinical Trial
Meunier PJ, Slosman DO, Delmas PD, Sebert JL, et al.
📚 223 cit.🎯 RCR 6.24🩺 Clinique
Recommandations1
▼
Recommandations1
▼- Comparison of four morphometric definitions and a semiquantitative consensus reading for assessing prevalent vertebral fractures
Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA · 2001 · Comparative Study
Grados F, Roux C, de Vernejoul MC, Utard G, et al.
📚 81 cit.🎯 RCR 2.72🔬→🩺 Translationnel