📇 Rhumatologue · CHERBOURG OCTEVILLE · (50) · Libéral
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2 raisons identifiées
Praticien-chercheur
19 articles scientifiques publiés — formation continue solide
Délais de RDV courts dans la région
107.5 rhumatos / 100 000 hab. — département bien doté
✨ Génération du profil synthétique IA en cours…
Indicateurs publics agrégés sur 250 M+ d'œuvres scientifiques (OpenAlex, PubMed). Traduits ici en langage patient.
Influence scientifique
Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.
53
53 articles ont été cités au moins 53fois par d'autres chercheurs — preuve que ses travaux sont repris par la communauté médicale.
h-index
Total citations reçues
11 402
Nombre de fois où d'autres équipes ont mentionné ses publications dans leurs propres travaux.
Publications totales
102
Articles, revues et chapitres référencés dans les bases académiques internationales.
Articles influents
81
Publications ayant marqué leur domaine — chacune citée au moins 10 fois par d'autres chercheurs.
i10-index
Thématiques principales
Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.
Articles déposés en accès libre sur l'archive ouverte des universités françaises (HAL) — gage d'activité de recherche en France.
Design and Micro Mechanical Modeling of Bio-fibre Reinforced Polymer Composites for Creep Resistant Piping Application
2025ArticleJournal of Engineering Research and Reports
Search for quantum black hole production in lepton+jet final states using proton-proton collisions at $\sqrt{s}$ = 13 TeV with the ATLAS detector
2024ArticlePhys.Rev.D
Food Preponderance Index and Feeding Habit of Macrognathus pancalus, (Hamilton, 1822) from Kotpally Reservoir Vikarabad District, Telangana State, India
2023ArticleUTTAR PRADESH JOURNAL OF ZOOLOGY
Observation of electroweak production of two jets and a $Z$-boson pair
2023ArticleNature Phys.
Measurement of cross-sections for production of a $Z$ boson in association with a flavor-inclusive or doubly $b$-tagged large-radius jet in proton-proton collisions at $\sqrt{s} = 13~$TeV with the ATLAS experiment
2023ArticlePhys.Rev.D
Measurements of jet observables sensitive to b-quark fragmentation in tt¯ events at the LHC with the ATLAS detector
2022ArticlePhys.Rev.D
Constraints on Higgs boson properties using $WW^{*}(\rightarrow e\nu \mu \nu )jj$ production in $36.1\,\mathrm{fb}^{-1}$ of $\sqrt{s}=13$ TeV pp collisions with the ATLAS detector
2022ArticleEur.Phys.J.C
Two-particle Bose–Einstein correlations in ${ pp }$ collisions at $\mathbf {\sqrt{s} = 13}$ TeV measured with the ATLAS detector at the LHC
2022ArticleEur.Phys.J.C
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
CABINET DU DR SAMUEL DAVID
2 RUE DU VIMEU, 50130 CHERBOURG OCTEVILLE
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Acta neuropathologica communications · 2018
Nature medicine · 2022
Abstract Cancers arising from germline DNA mismatch repair deficiency or polymerase proofreading deficiency (MMRD and PPD) in children harbour the highest mutational and microsatellite insertion–deletion (MS-indel) burden in humans. MMRD and PPD cancers are commonly lethal due to the inherent resistance to chemo-irradiation. Although immune checkpoint inhibitors (ICIs) have failed to benefit children in previous studies, we hypothesized that hypermutation caused by MMRD and PPD will improve outcomes following ICI treatment in these patients. Using an international consortium registry study, we report on the ICI treatment of 45 progressive or recurrent tumors from 38 patients. Durable objective responses were observed in most patients, culminating in a 3 year survival of 41.4%. High mutation burden predicted response for ultra-hypermutant cancers (>100 mutations per Mb) enriched for combined MMRD + PPD, while MS-indels predicted response in MMRD tumors with lower mutation burden (10–100 mutations per Mb). Furthermore, both mechanisms were associated with increased immune infiltration even in ‘immunologically cold’ tumors such as gliomas, contributing to the favorable response. Pseudo-progression (flare) was common and was associated with immune activation in the tumor microenvironment and systemically. Furthermore, patients with flare who continued ICI treatment achieved durable responses. This study demonstrates improved survival for patients with tumors not previously known to respond to ICI treatment, including central nervous system and synchronous cancers, and identifies the dual roles of mutation burden and MS-indels in predicting sustained response to immunotherapy.
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Clinical biomechanics (Bristol, Avon) · 2026 · Journal Article
Hansen L, Ebbecke J, David S, Rogoschin J, et al.
The Lancet. Respiratory medicine · 2026 · Journal Article
Azoulay E, McEvoy C, Castro P, Hssain AA, et al.
Theranostics · 2023 · Journal Article
Oprişoreanu AM, Ryan F, Richmond C, Dzekhtsiarova Y, et al.
Journal of clinical medicine · 2023 · Journal Article
Ring A, Sieber WA, Studt JD, Schuepbach RA, et al.
Journal of menopausal medicine · 2022 · Journal Article
Gandhi K, Manales NJ, Garza J, David S, et al.
Gynecologic oncology · 2019 · Journal Article
Samuel D, Vilardo N, Isani SS, Kuo DYS, et al.
The Lancet. Oncology · 2024 · Journal Article
Ercan AB, Aronson M, Fernandez NR, Chang Y, et al.
Journal of hematology & oncology · 2024 · Research Support, Non-U.S. Gov't
Kastellan S, Kalb R, Sajjad B, McReynolds LJ, et al.
The Lancet. Oncology · 2018 · Journal Article
Waszak SM, Northcott PA, Buchhalter I, Robinson GW, et al.
Acta neuropathologica · 2019 · Journal Article
López GY, Van Ziffle J, Onodera C, Grenert JP, et al.
Acta neuropathologica communications · 2018 · Journal Article
Pekmezci M, Villanueva-Meyer JE, Goode B, Van Ziffle J, et al.
The Lancet. Oncology · 2018 · Journal Article
Waszak SM, Northcott PA, Buchhalter I, Robinson GW, et al.
NPJ precision oncology · 2023 · Journal Article
Sievers P, Sill M, Schrimpf D, Abdullaev Z, et al.
Frontiers in oncology · 2022 · Journal Article
Kline C, Stoller S, Byer L, Samuel D, et al.
Nature medicine · 2022 · Journal Article
Das A, Sudhaman S, Morgenstern D, Coblentz A, et al.
The Lancet. Oncology · 2018 · Journal Article
Waszak SM, Northcott PA, Buchhalter I, Robinson GW, et al.
World neurosurgery: X · 2024 · Journal Article
Olukoya O, Osunronbi T, Jesuyajolu DA, Uwaga BC, et al.
Cureus · 2022 · Case Reports
David S, Davidson SO, Grigorian R
Cancer medicine · 2025 · Journal Article
Chan Sanchez SK, David SV, Polychronopoulou E, Raji M, et al.
BMJ open · 2023 · Journal Article
Ikwuegbuenyi CA, Ooi SZY, Takoutsing BD, Jesuyajolu DA, et al.
BMJ case reports · 2025 · Journal Article
Jackson-Cross HJ, David S
Cancer medicine · 2025 · Journal Article
Chan Sanchez SK, David SV, Polychronopoulou E, Raji M, et al.
Additional file 4 of Ferroptosis induces detrimental effects in chronic EAE and its implications for progressive MS
Additional file 4: Figure 4. Quantification of double immunofluorescence labelled cells of Human tissue sections.
Ferroptosis induces detrimental effects in chronic EAE and its implications for progressive MS
Abstract Ferroptosis is a form of lipid peroxidation-mediated cell death and damage triggered by excess iron and insufficiency in the glutathione antioxidant pathway. Oxidative stress is thought to play a crucial role in
Additional file 3 of Ferroptosis induces detrimental effects in chronic EAE and its implications for progressive MS
Additional file 3: Figure 3. LHE-ORO staining and iron histochemistry of human MS tissue sections.
Additional file 2 of Ferroptosis induces detrimental effects in chronic EAE and its implications for progressive MS
Additional file 2: Figure 2. Western blots.
Additional file 2 of Ferroptosis induces detrimental effects in chronic EAE and its implications for progressive MS
Additional file 2: Figure 2. Western blots.
Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).