Docteur ALAIN CLEMENT
✨ Profil synthétique
IA · 06/05/2026Le Docteur Alain Clément est un rhumatologue avec une production scientifique importante, comme en témoignent ses 213 publications et un h-index de 16. Ses recherches semblent cependant se concentrer davantage sur des domaines tels que l'histoire économique et sociale, les études urbaines et sociales françaises, ainsi que l'analyse de l'histoire politique européenne. Ses publications sur PubMed suggèrent une implication dans des études sur la pédiatrie, les traitements anti-IL-17 et la génétique.
Expertises présumées
- Pédiatrie
- Traitements anti-IL-17
- Génétique
- Rhumatologie pédiatrique
- Thérapies biologiques
- Génétique des maladies rhumatismales
- Pathologies auto-immunes
Synthèse automatique à partir des sources publiques (HAL, OpenAlex, theses.fr, ClinicalTrials.gov, FAI²R, ANS). Pas une évaluation clinique. Le médecin peut corriger via son compte.
Diplômes
🎓 DES & spécialité ordinale
- Rhumatologie (SM)
🎓 Diplômes
- DE Docteur en médecine
Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.
Activité de recherche & publications
Source : bases de données publiques (OpenAlex, PubMed).
h-index
16
h articles cités ≥ h fois chacun. Un h de 16 = 16 publications avec 16+ citations.
Citations
1 881
Publications
213
i10-index
23
Thématiques principales
- Historical Economic and Social Studies ×25
- French Urban and Social Studies ×23
- European Political History Analysis ×21
- Economic Theory and Institutions ×15
- Political Economy and Marxism ×15
Source : OpenAlex (CC0, OurResearch). Indicateurs académiques agrégés sur 250 M+ d'œuvres.
Bibliographie
Automatic Detection of Flavonoids from Spectroscopic Images by Fusion of Two-Dimensional Convolution Product with Multi-Scale Textural Descriptors
2026ArticleAdvances in Materials Physics and Chemistry
IDENTIFICATION OF MAJOR MINERALS IN IGNEOUS ROCK MICROSCOPIC IMAGES FROM THIN SECTIONS THROUGH DEEP NEURAL NETWORK ANALYSIS
2025ArticleArtificial Intelligence in Geosciences
Optimal Classification of Minerals by Microscopic Image Analysis Based on Seven-State “Deep Learning” Combined with Optimizers
2024ArticleOpen Journal of Applied Sciences
Quantitative Comparative Study of the Performance of Lossless Compression Methods Based on a Text Data Model
2024ArticleOpen Journal of Applied Sciences
Direction colloque Surveillance (35 intervenants), L. Laref, M. Laref
2023CongrèsL. Laref, M. Laref (dir.), Surveillance, Colloque des 6 et 7 avril 2023, organisé à la Faculté de droit de l'UCLille. Colloque organisé dans le cadre d’un projet de recherche INES, en partenariat avec les éditions Dalloz, les revues AJ Pénal Dalloz et Dalloz iP/iT, le Ministère de la Justice-Ecole Nationale d’Administration Pénitentiaire, le Centre Interdisciplinaire de Recherche Appliquée au champ Pénitentiaire (CIRAP), l’Institut des Hautes Etudes du Ministère de l’Intérieur (IHEMI) et avec le soutien du Centre de Recherche sur les Relations entre les Risques et le Droit (C3RD), l'UCLille, la Fondation de la catho, la région Haut-de-France. 35 intervenants.
Smoke and fire detection by a convolutional neural network based on a combinatorial model
2023ArticleInternational Journal of Innovation and Applied Studies
An alternative expression of the time domain free surface Green function for deep water
2023ArticleOcean Engineering
Method of Estimation of Chemical Compounds of a Solution by Analysis of Video Images of Titration from a Semi-Automatic Approach
2022ArticleOpen Journal of Applied Sciences
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
Lieu de consultation
Tarifs & secteur de conventionnement
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Prendre rendez-vous & contact
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
Articles de presse (2)
Source : Google News (recherche par nom complet — homonymes possibles, vérifier le contenu).
- Bassin d’Arcachon : deux poètes qui font chanter les mots - Sud Ouest
📰 Sud Ouest · 14/10/2020
<a href="https://news.google.com/rss/articles/CBMirAFBVV95cUxORkw1c21GN08yWng0ZTRKbmRzVHYyQmItLUdDeHhEMmwyVzhaWEJxRGJXcHRXa3NaZktLMV9PcTZSTXJFMnR5WW1lbDJGSG0yOVczcWg1Q2ZnYTNkRDJEaVQ5SHZOX3pTV2F1bmhNZUNDTkZQZEJhcXNDZHdDcWdncG1IaEd1Wnd0NG83N1NWblg1QWVHQTRTanhaellXOWVya20ySmpaVXdxdy1y?oc=5" target="_bl
- Un après-midi de recueillement à Erquy - Ouest-France
📰 Ouest-France · 04/08/2014
<a href="https://news.google.com/rss/articles/CBMiiAFBVV95cUxOdzBKTW5kTFczVW9IUVhXTkhTZjd0N0xveml4THBZNGJ4cGdqRWVZdHlqUGRrM3g5X1lKVDFfMWJvV3RQSTl5MTJJTjhtVTdmbDJUSGFQNGdZMzJOQXg5WGM2c0stYnRUVjBDVTVHZjl0bUd5cHpLNGVRTnFhc1FocEJtSE9IOGtz?oc=5" target="_blank">Un après-midi de recueillement à Erquy</a>&
Top publications · les plus citées
- 1MUC5B Promoter Variant and Rheumatoid Arthritis with Interstitial Lung Disease
The New England journal of medicine · 2018
- 2Shared genetic predisposition in rheumatoid arthritis-interstitial lung disease and familial pulmonary fibrosis
The European respiratory journal · 2017
Lire l'abstract Crossref ↓
Despite its high prevalence and mortality, little is known about the pathogenesis of rheumatoid arthritis-associated interstitial lung disease (RA-ILD). Given that familial pulmonary fibrosis (FPF) and RA-ILD frequently share the usual pattern of interstitial pneumonia and common environmental risk factors, we hypothesised that the two diseases might share additional risk factors, including FPF-linked genes. Our aim was to identify coding mutations of FPF-risk genes associated with RA-ILD.We used whole exome sequencing (WES), followed by restricted analysis of a discrete number of FPF-linked genes and performed a burden test to assess the excess number of mutations in RA-ILD patients compared to controls.Among the 101 RA-ILD patients included, 12 (11.9%) had 13 WES-identified heterozygous mutations in theTERT,RTEL1,PARNorSFTPCcoding regions.The burden test, based on 81 RA-ILD patients and 1010 controls of European ancestry, revealed an excess ofTERT,RTEL1,PARNorSFTPCmutations in RA-ILD patients (OR 3.17, 95% CI 1.53–6.12; p=9.45×10−4). Telomeres were shorter in RA-ILD patients with aTERT,RTEL1orPARNmutation than in controls (p=2.87×10−2).Our results support the contribution of FPF-linked genes to RA-ILD susceptibility.
- 3Use of ruxolitinib in COPA syndrome manifesting as life-threatening alveolar haemorrhage
Thorax · 2020
Lire l'abstract Crossref ↓
COPA (coatomer subunit α) syndrome is a newly recognised cause of interstitial lung disease in children and adults, frequently associated with arthritis and renal dysfunction. We report a 11-year-old girl with disease limited to major pulmonary haemosiderosis manifesting at the age of 2 years, due to a heterozygous p.(Arg233His) mutation inCOPA. Her interferon (IFN) signature was elevated (10.312 and 12.429, healthy <2.466), as was the level of serum IFNα (211 fg/mL, healthy <10 fg/mL). STAT1 phosphorylation in T lymphocytes and monocytes was increased as compared with healthy controls. Based on these results she was treated with the JAK1/2 inhibitor ruxolitinib, which resulted in reduction in IFN signalling and appeared to be associated with partial though incomplete decrease in the severity of her pulmonary disease. Patients with alveolar haemorrhage of unknown origin should be considered forCOPAscreening. Functional tests can help to personalise patient therapy.
Publications scientifiques (16) — classées par pathologie
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Transversal12
▼
Transversal12
▼- Secondary Linburg-Comstock syndrome post-trapeziectomy surgery
BMJ case reports · 2024 · Journal Article
Lim B, Clement A, Sen S
- COPB2 loss of function causes a coatopathy with osteoporosis and developmental delay
American journal of human genetics · 2021 · Journal Article
Marom R, Burrage LC, Venditti R, Clément A, et al.
📚 34 cit.🎯 RCR 2.05 - Evaluating the maternal and perinatal sequelae of severe gestational hypertension
American journal of obstetrics & gynecology MFM · 2021 · Journal Article
Kumar NR, Grobman WA, Barry O, Clement AC, et al.
📚 6 cit.🔬→🩺 Translationnel - Use of ruxolitinib in COPA syndrome manifesting as life-threatening alveolar haemorrhage
Thorax · 2020 · Case Reports
Frémond ML, Legendre M, Fayon M, Clement A, et al.
📚 41 cit.🎯 RCR 1.89 - Pilot experience of multidisciplinary team discussion dedicated to inherited pulmonary fibrosis
Orphanet journal of rare diseases · 2019 · Journal Article
Borie R, Kannengiesser C, Gouya L, Dupin C, et al.
📚 28 cit.🎯 RCR 1.32🔬→🩺 Translationnel - MUC5B Promoter Variant and Rheumatoid Arthritis with Interstitial Lung Disease
The New England journal of medicine · 2018 · Journal Article
Juge PA, Lee JS, Ebstein E, Furukawa H, et al.
📚 395 cit.🎯 RCR 18.18🔬→🩺 Translationnel - Evaluation of automatic feature detection algorithms in EEG: application to interburst intervals
Computers in biology and medicine · 2014 · Journal Article
Chauvet PE, Tich SN, Schang D, Clément A
📚 6 cit. - Research in progress: put the orphanage out of business
Thorax · 2013 · Journal Article
Bush A, Anthony G, Barbato A, Cunningham S, et al.
📚 24 cit.🔬→🩺 Translationnel - Cholesterol-like effects of selective cyclooxygenase inhibitors and fibrates on cellular membranes and amyloid-beta production
Molecular pharmacology · 2007 · Journal Article
Gamerdinger M, Clement AB, Behl C
📚 30 cit. - Advanced in the treatment of the menopause and osteoporosis
British journal of obstetrics and gynaecology · 1994 · Conference Proceedings
Clement A
📚 2 cit. - Peripheral neuropathy with essential mixed cryoglobulinemia: biopsies from 5 cases
Acta neuropathologica · 1988 · Case Reports
Vital C, Deminière C, Lagueny A, Bergouignan FX, et al.
📚 36 cit.🎯 RCR 1.83 - [Osmic acid synoviorthesis in non-tuberculous osteoarticular infections]
Revue du rhumatisme et des maladies osteo-articulaires · 1981 · Journal Article
Desproges-Gotteron R, Labrousse C, Treves R, Dibon JM, et al.
📚 1 cit.
Pédiatrie2
▼
Pédiatrie2
▼- Pulmonary hemosiderosis in children with Down syndrome: a national experience
Orphanet journal of rare diseases · 2018 · Journal Article
Alimi A, Taytard J, Abou Taam R, Houdouin V, et al.
📚 36 cit.🎯 RCR 2.45🔬→🩺 Translationnel - Paediatric sarcoidosis
Paediatric respiratory reviews · 2005 · Journal Article
Fauroux B, Clément A
📚 36 cit.🎯 RCR 1.27
Anti-IL-171
▼
Anti-IL-171
▼- Negative association between autoantibodies against IL-17, IL-17/anti-IL-17 antibody immune complexes and destruction in rheumatoid arthritis
Annals of the rheumatic diseases · 2016 · Comparative Study
Ndongo-Thiam N, Clement A, Pin JJ, Razanajaona-Doll D, et al.
📚 13 cit.
Génétique1
▼
Génétique1
▼- Shared genetic predisposition in rheumatoid arthritis-interstitial lung disease and familial pulmonary fibrosis
The European respiratory journal · 2017 · Journal Article
Juge PA, Borie R, Kannengiesser C, Gazal S, et al.
📚 186 cit.🎯 RCR 7.39🔬→🩺 Translationnel
Datasets & protocoles partagés
Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).
