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Rhumatologue

Docteur Romane BOUCHARDIE

📍 Saint-Aignan (41)HospitalierRPPS 10101945417

✨ Profil synthétique

IA · 01/05/2026

Le Docteur Romane BOUCHARDIE est un rhumatologue hospitalier à Saint-Aignan. Ses publications sur PubMed couvrent divers aspects de la rhumatologie, notamment les vascularites des gros vaisseaux et les biomarqueurs. Ses travaux incluent également des revues générales, des méta-analyses et des études épidémiologiques.

Expertises présumées

  • Vascularites des gros vaisseaux
  • Biomarqueurs en rhumatologie
  • Épidémiologie des maladies rhumatismales
  • Auto-anticorps
  • Revue systématique et méta-analyse
  • Étude de cas en rhumatologie
  • Registres de maladies rhumatismales

Synthèse automatique à partir des sources publiques (HAL, OpenAlex, theses.fr, ClinicalTrials.gov, FAI²R, ANS). Pas une évaluation clinique. Le médecin peut corriger via son compte.

Diplômes

🎓 DES & spécialité ordinale

  • DES Rhumatologie
  • Rhumatologie (SM)

🎓 Diplômes

  • DE Docteur en médecine

Source : Annuaire Santé ANS (FHIR Practitioner.qualification) · Mises à jour quotidiennes.

Localisation

Adresses géocodées via la Base Adresse Nationale (api-adresse.data.gouv.fr). Précision indicative.

Lieu de consultation

Tarifs & secteur de conventionnement

Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).

Prendre rendez-vous & contact

Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).

Top publications · les plus citées

  • 1
    Circulatory Glutamine/Glucose ratio for evaluating disease activity in Takayasu arteritis: A NMR based serum metabolomics study

    Journal of pharmaceutical and biomedical analysis · 2020

    📚 36 citations🎯 RCR 2.67Top 19% NIH🔓 Open Access
  • 2
    Molecular basis of RNA-binding and autoregulation by the cancer-associated splicing factor RBM39

    Nature communications · 2023

    📚 29 citations🎯 RCR 2.59Top 19% NIH🔓 Open Access📄 PDF gratuit ↗
    Lire l'abstract Crossref ↓

    AbstractPharmacologic depletion of RNA-binding motif 39 (RBM39) using aryl sulfonamides represents a promising anti-cancer therapy but requires high levels of the adaptor protein DCAF15. Consequently, novel approaches to deplete RBM39 in an DCAF15-independent manner are required. Here, we uncover that RBM39 autoregulates via the inclusion of a poison exon into its own pre-mRNA and identify the cis-acting elements that govern this regulation. We also determine the NMR solution structures of RBM39’s tandem RNA recognition motifs (RRM1 and RRM2) bound to their respective RNA targets, revealing how RRM1 recognises RNA stem loops whereas RRM2 binds specifically to single-stranded N(G/U)NUUUG. Our results support a model where RRM2 selects the 3’-splice site of a poison exon and the RRM3 and RS domain stabilise the U2 snRNP at the branchpoint. Our work provides molecular insights into RBM39-dependent 3’-splice site selection and constitutes a solid basis to design alternative anti-cancer therapies.

  • 3
    Hip abductor strengthening in patients diagnosed with knee osteoarthritis - a systematic review and meta-analysis

    BMC musculoskeletal disorders · 2022

    📚 27 citations🎯 RCR 4.34Top 10% NIH🔓 Open Access📄 PDF gratuit ↗
    Lire l'abstract Crossref ↓

    Abstract Background Globally osteoarthritis of the knee is a leading cause of disability. Hip abductor strength and activation are essential for maintaining postural balance during transfers and are related to joint loading and progression during weight-bearing activities. Strength deficits in the hip abductors might cause a reduction in the lower extremity force generation, thereby causing stress on the medial tibiofemoral joint. The aim of this systematic review is to assess the effectiveness of hip abductor strengthening on knee joint loading, knee pain and functional outcome measures in patients with knee osteoarthritis. Methods Database such as Scopus, PubMed, EMBASE, Cochrane Central Register of Controlled Trials (CENTRAL) database and PEDro were reviewed to recognize the trials published in English from inception to December 2020. Randomized controlled trials that studied the effectiveness of hip abductor strengthening in subjects with knee osteoarthritis and its impact on knee joint loading, knee pain and functional outcome measures were included. RevMan 5.4 was used for meta-analysis and forest plot construction. Quality assessment of the included studies was carried out using the PEDro scale. Results and discussion The search yielded 260 results of which 29 full-text articles were screened. The review includes 7 randomized controlled trials and 3 studies with good methodological quality were included for meta-analysis. The meta-analysis of the articles favored hip abductor strengthening intervention over the control group. Hip abductor strengthening had significantly reduced the VAS [ SMD = -0.60[-0.88, -0.33] p < 0.0001]at 95% CI and improved the WOMAC scores [SMD – 0.75[-1.05,-0.45] p < 0.0001] at 95% CI. All of the included studies concluded that strengthening the hip abductor muscle had a positive impact on knee pain and functional outcomes. Conclusion The current study found high-quality evidence to support the use of hip abductor muscle strengthening exercises as a rehabilitative treatment for subjects with knee osteoarthritis. Trial registration CRD42021256251.

Publications scientifiques (50) — classées par pathologie

Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).

Transversal31

Revue générale7

Revue / méta-analyse3

Épidémiologie & registres2

Vascularites des gros vaisseaux2

Biomarqueurs / Auto-Ac1

Case report / série1

csDMARDs1

Essai clinique1

Génétique1

Ostéoporose1

Santé mentale / fatigue1

SAPL1

Sclérodermie1

Vraie vie / RWE1

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