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2 raisons identifiées
Auteur de référence en rhumatologie
20 articles scientifiques publiés — un praticien à la pointe de la recherche
Délais de RDV courts dans la région
110.1 rhumatos / 100 000 hab. — département bien doté
✨ Génération du profil synthétique IA en cours…
Articles déposés en accès libre sur l'archive ouverte des universités françaises (HAL) — gage d'activité de recherche en France.
Données ANS publiques (Licence Ouverte 2.0) · Enrichissements MonRhumato 100 % opt-in · Toute personne référencée peut demander la suppression ou la rectification.
Source : HAL — archive ouverte CCSD/CNRS (couvre articles, chapitres EMC, communications congrès, thèses).
CABINET DU DR MARC BAUMANN
49 RUE DE BALE, 68100 MULHOUSE
Secteur de conventionnement non disponible (médecin hospitalier ou non présent dans l'Annuaire santé CNAM des libéraux conventionnés).
Lien Doctolib = recherche Google site:doctolib.fr (le 1er résultat est presque toujours le profil correct s'il existe).
The Knee · 2016
The Journal of clinical investigation · 2013
Acta neuropathologica communications · 2013
AbstractBackgroundThe Arctic mutation (p.E693G/p.E22G)fs within the β-amyloid (Aβ) region of the β-amyloid precursor protein gene causes an autosomal dominant disease with clinical picture of typical Alzheimer’s disease. Here we report the special character of Arctic AD neuropathology in four deceased patients.ResultsAβ deposition in the brains was wide-spread (Thal phase 5) and profuse. Virtually all parenchymal deposits were composed of non-fibrillar, Congo red negative Aβ aggregates. Congo red only stained angiopathic vessels. Mass spectrometric analyses showed that Aβ deposits contained variably truncated and modified wild type and mutated Aβ species. In three of four Arctic AD brains, most cerebral cortical plaques appeared targetoid with centres containing C-terminally (beyond aa 40) and variably N-terminally truncated Aβ surrounded by coronas immunopositive for Aβx-42. In the fourth patient plaque centres contained almost no Aβ making the plaques ring-shaped. The architectural pattern of plaques also varied between different anatomic regions. Tau pathology corresponded to Braak stage VI, and appeared mainly as delicate neuropil threads (NT) enriched within Aβ plaques. Dystrophic neurites were scarce, while neurofibrillary tangles were relatively common. Neuronal perikarya within the Aβ plaques appeared relatively intact.ConclusionsIn Arctic AD brain differentially truncated abundant Aβ is deposited in plaques of variable numbers and shapes in different regions of the brain (including exceptional targetoid plaques in neocortex). The extracellular non-fibrillar Aβ does not seem to cause overt damage to adjacent neurons or to induce formation of neurofibrillary tangles, supporting the view that intracellular Aβ oligomers are more neurotoxic than extracellular Aβ deposits. However, the enrichment of NTs within plaques suggests some degree of intra-plaque axonal damage including accumulation of hp-tau, which may impair axoplasmic transport, and thereby contribute to synaptic loss. Finally, similarly as the cotton wool plaques in AD resulting from exon 9 deletion in the presenilin-1 gene, the Arctic plaques induced only modest glial and inflammatory tissue reaction.
Source PubMed · Recherche par auteur (homonymes possibles, vérifier l'affiliation).
Nature communications · 2026 · Journal Article
Gholizadeh E, Zangene E, Vadadokhau U, Ritz D, et al.
Wiener medizinische Wochenschrift (1946) · 2026 · English Abstract
Obermayr V, Pichler I, Appelt D, Baumann M, et al.
Rheumatology (Oxford, England) · 2022 · Letter
Förger F, Raio L, Baumann M
Cell death discovery · 2020 · Journal Article
Doccini S, Morani F, Nesti C, Pezzini F, et al.
European journal of obstetrics, gynecology, and reproductive biology · 2019 · Journal Article
Trottmann F, Baumann M, Amylidi-Mohr S, Surbek D, et al.
Best practice & research. Clinical endocrinology & metabolism · 2019 · Journal Article
Hürter H, Vontelin van Breda S, Vokalova L, Brandl M, et al.
Neuromolecular medicine · 2016 · Journal Article
Tikka S, Monogioudi E, Gotsopoulos A, Soliymani R, et al.
Laboratory investigation; a journal of technical methods and pathology · 2014 · Comparative Study
Jain A, Schneider H, Aliyev E, Soydemir F, et al.
Acta neuropathologica communications · 2013 · Case Reports
Kalimo H, Lalowski M, Bogdanovic N, Philipson O, et al.
The Journal of clinical investigation · 2013 · Journal Article
Papacleovoulou G, Abu-Hayyeh S, Nikolopoulou E, Briz O, et al.
Journal of gynecologic oncology · 2013 · Journal Article
Fehr MK, Baumann M, Mueller M, Fink D, et al.
Journal inconnu · 1993 · Review
Adam MP, Bick S, Mirzaa GM, Pagon RA, et al.
Geburtshilfe und Frauenheilkunde · 2025 · Journal Article
Pecks U, Baumann M, Binder J, Contini C, et al.
The Knee · 2016 · Journal Article
Niemeyer P, Albrecht D, Andereya S, Angele P, et al.
Molecular pharmacology · 2021 · Journal Article
Gholizadeh E, Karbalaei R, Khaleghian A, Salimi M, et al.
Geburtshilfe und Frauenheilkunde · 2025 · Journal Article
Pecks U, Baumann M, Binder J, Contini C, et al.
Ginekologia polska · 2012 · Comparative Study
Mueller MM, Baumann MU, Mueller MD, Kuhn A
Acta obstetricia et gynecologica Scandinavica · 2021 · Evaluation Study
Trottmann F, Raio L, Amylidi-Mohr S, Mosimann B, et al.
Journal of cellular physiology · 2015 · Journal Article
Coe LM, Tekalur SA, Shu Y, Baumann MJ, et al.
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society · 2025 · Journal Article
Panagi M, Blaschek A, Selek A, Baumann M, et al.
Expert review of proteomics · 2017 · Journal Article
Scifo E, Calza G, Fuhrmann M, Soliymani R, et al.
Source : DataCite — DOIs pour datasets, logiciels, protocoles, registres patient. Hors articles (déjà couverts).